FOLITRAX 10MG TABLET 10'S
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FOLITRAX 10MG TABLET 10'S
FOLITRAX 10MG TABLET 10'S
FOLITRAX 10MG TABLET 10'S
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FOLITRAX 10MG TABLET 10'S

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FOLITRAX 10MG TABLET 10'S

By IPCA LABORATORIES LIMITED

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139.55

₹118.62

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About FOLITRAX 10MG TABLET 10'S

  • FOLITRAX 10MG TABLET 10'S is a medication prescribed for the treatment of various cancers, including those affecting the breasts, head, neck, lungs, blood, bone, lymph nodes, and uterus. It is also used in the management of rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
  • FOLITRAX 10MG TABLET 10'S can be administered as a single agent or in conjunction with other medications, depending on the specific treatment plan determined by your doctor. It is crucial to adhere to your doctor's instructions regarding dosage and administration. Exceeding the prescribed dose can lead to serious adverse effects. While it may take several weeks or months to experience the full therapeutic benefits, it is essential to continue taking the medication as directed unless otherwise instructed by your physician. It is strongly advised to avoid alcohol consumption during treatment with this medicine, as it may elevate the risk of liver damage.
  • Common side effects associated with FOLITRAX 10MG TABLET 10'S include ulcerative stomatitis (mouth sores), hair loss, decreased blood cell counts, elevated liver enzyme levels, nausea, and abdominal discomfort. Your doctor may recommend folic acid supplementation to mitigate some of these side effects. If these side effects persist or worsen, promptly inform your doctor. There may be strategies available to prevent or alleviate these effects. This medication may compromise your body's ability to fight infections and potentially cause issues with your blood, liver, or kidneys. To monitor for these potential complications, your doctor may conduct regular blood tests, X-rays, and physical examinations before and during treatment with FOLITRAX 10MG TABLET 10'S.
  • Before initiating treatment with FOLITRAX 10MG TABLET 10'S, inform your doctor if you have any pre-existing conditions affecting the stomach, liver, or kidneys, or if you are currently taking any medications for infections. It's important to disclose all medications you are taking to your healthcare team, as many drugs can interact with FOLITRAX 10MG TABLET 10'S, either affecting its efficacy or increasing the risk of side effects. This medicine is generally not recommended for use during pregnancy or while breastfeeding, as it may pose a risk to the developing baby.
  • Furthermore, it's important to maintain open communication with your healthcare provider regarding any changes in your health status or any new medications you may be prescribed during your treatment with FOLITRAX 10MG TABLET 10'S. Regular monitoring and proactive management of potential side effects can help ensure the safest and most effective treatment outcome.

Uses of FOLITRAX 10MG TABLET 10'S

  • Treatment of Cancer involves a multifaceted approach aimed at eliminating cancerous cells and preventing their spread throughout the body.
  • Treatment of Rheumatoid arthritis focuses on alleviating pain, reducing inflammation, and slowing down the progression of joint damage caused by the autoimmune disorder.
  • Treatment of Psoriasis aims to manage skin inflammation, reduce scaling and itching, and improve the overall appearance and comfort of the skin affected by the chronic condition.
  • Treatment of Crohn’s disease involves managing inflammation in the digestive tract, relieving symptoms such as abdominal pain and diarrhea, and preventing complications associated with the inflammatory bowel disease.

How FOLITRAX 10MG TABLET 10'S Works

  • FOLITRAX 10MG TABLET 10'S works by inhibiting an enzyme called dihydrofolate reductase. This enzyme is crucial for cell division and growth. By blocking this enzyme, FOLITRAX 10MG TABLET 10'S effectively prevents cells from dividing and multiplying rapidly. This action also contributes to its anti-inflammatory properties, helping to reduce swelling and discomfort.
  • In the context of cancer treatment, FOLITRAX 10MG TABLET 10'S targets cancer cells by disrupting their ability to synthesize DNA. Since DNA is essential for cell replication, inhibiting its production effectively halts the growth and spread of cancerous cells. This mechanism makes FOLITRAX 10MG TABLET 10'S a valuable tool in chemotherapy regimens.
  • For individuals with psoriasis, FOLITRAX 10MG TABLET 10'S helps to manage the condition by slowing down the overproduction of skin cells. Psoriasis is characterized by rapid skin cell turnover, leading to the formation of thick, scaly patches. By inhibiting cell division, FOLITRAX 10MG TABLET 10'S reduces the rate at which these skin cells are produced, alleviating the symptoms of psoriasis. Additionally, its anti-inflammatory effects further soothe the affected skin.
  • In the treatment of rheumatoid arthritis, FOLITRAX 10MG TABLET 10'S acts as an immunosuppressant. It works by suppressing the activity of the immune system, preventing it from mistakenly attacking the body's own tissues. This helps to reduce the inflammation that causes swollen, stiff joints, characteristic of rheumatoid arthritis. Similarly, in Crohn's disease, FOLITRAX 10MG TABLET 10'S can help to reduce inflammation and damage to the bowel by modulating the immune response.

Side Effects of FOLITRAX 10MG TABLET 10'S
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In most instances, the side effects listed do not necessitate medical intervention and typically subside as the body adapts to the medication. However, it is advisable to seek medical advice if these effects persist or if you have any concerns.

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

Safety Advice for FOLITRAX 10MG TABLET 10'S
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Liver Function

Caution

FOLITRAX 10MG TABLET 10'S should be used with caution in patients with liver disease. Dose adjustment of FOLITRAX 10MG TABLET 10'S may be needed. Please consult your doctor.

Dosage of FOLITRAX 10MG TABLET 10'S
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  • For Children: The dosage for children is based on their body surface area (BSA) or weight. Typically, the starting dose ranges from 10 to 20 mg/m² per week, divided into several smaller doses. The dosage may be adjusted based on the child's response to treatment and any potential side effects.
  • For Adults: For adults, the dosage of FOLITRAX 10MG TABLET 10'S can vary depending on the condition being treated. For certain cancers, the typical starting dose ranges from 10 to 25 mg/m² per week, divided into several smaller doses. In the case of rheumatoid arthritis, the initial dosage is often lower, usually starting with 7.5 mg per week, which may be increased gradually.

How to store FOLITRAX 10MG TABLET 10'S?
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  • Keep FOLITRAX 10MG TAB 1X10 away from the reach of children and pets.
  • Store FOLITRAX 10MG TAB 1X10 at room temperature.

Benefits of FOLITRAX 10MG TABLET 10'S
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  • <b>Treatment of Cancer</b><br>FOLITRAX 10MG TABLET 10'S works by slowing down the proliferation of cancer cells within the body. It is indicated for the management of various malignancies, including acute leukemias, non-Hodgkin’s lymphoma, and solid tumors affecting the breast, lung, bladder, head, neck, cervix, ovaries, and testicles. This medication may be administered as a single agent or in conjunction with other chemotherapeutic drugs. Given its potency and potential toxicity, a thorough discussion of the risks and benefits with your healthcare provider is essential before initiating treatment. It is crucial to abstain from alcohol consumption during treatment and maintain adequate hydration by drinking plenty of water. Regular monitoring and adherence to your doctor's instructions are vital for managing potential side effects and optimizing treatment outcomes.
  • <b>Treatment of Rheumatoid Arthritis</b><br>FOLITRAX 10MG TABLET 10'S is classified as an antimetabolite and may be considered for the treatment of severe rheumatoid arthritis when other therapeutic options have proven ineffective. It is not typically used as a first-line treatment. Its mechanism of action involves suppressing the body's immune system, which subsequently reduces swelling, alleviates pain and stiffness, and enhances joint function. For optimal results, it is imperative to adhere strictly to the prescribed dosage and duration of treatment. Avoid exceeding the recommended dose. The full therapeutic effects may not be evident for several months.
  • <b>Treatment of Psoriasis</b><br>FOLITRAX 10MG TABLET 10'S, an antimetabolite, may be prescribed for the management of severe psoriasis in cases where other treatments have been unsuccessful. Psoriasis is characterized by the rapid proliferation of skin cells. FOLITRAX 10MG TABLET 10'S functions by targeting and eliminating these rapidly dividing cells. Due to its potency and potential toxicity, a comprehensive discussion of the risks and benefits with your physician is crucial. It is essential to follow the prescribed dosage and treatment duration meticulously to maximize benefits. Do not exceed the recommended dosage. Full therapeutic effects may take several months to manifest. Abstain from alcohol consumption during treatment and ensure adequate hydration by drinking plenty of water.
  • <b>Treatment of Crohn’s Disease</b><br>Crohn’s disease is a chronic inflammatory condition affecting the intestines. Common symptoms include diarrhea and abdominal pain. FOLITRAX 10MG TABLET 10'S aids in reducing inflammation, alleviating symptoms, and preventing disease recurrence. It helps in managing the overactive immune response that contributes to the inflammation in the digestive tract, thus providing relief and improving the patient's quality of life.

How to use FOLITRAX 10MG TABLET 10'S
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  • Always adhere to your doctor's instructions regarding the dosage and duration of FOLITRAX 10MG TABLET 10'S. It is crucial to follow their recommendations for optimal results and to minimize potential side effects.
  • Swallow the tablet whole with a glass of water. Avoid altering the tablet's form by chewing, crushing, or breaking it, as this can affect how the medication is absorbed into your system. Maintaining the integrity of the tablet ensures that the medication is released properly.
  • FOLITRAX 10MG TABLET 10'S can be taken either with or without food. However, for the sake of consistency and to help you remember, it is advisable to take it at a fixed time each day. This regular schedule helps maintain a steady level of the medication in your body, which can improve its effectiveness.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. This is to avoid any potential overdose.
  • If you have any discomfort or reactions after taking the medicine, consult the doctor immediately.

Quick Tips for FOLITRAX 10MG TABLET 10'S
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  • Stay well-hydrated by drinking plenty of fluids while using FOLITRAX 10MG TABLET 10'S. Adequate hydration can help minimize potential side effects and support overall well-being during treatment. Aim for water, herbal teas, or diluted juices throughout the day.
  • If your doctor recommends it, take folic acid supplements. Folic acid can help mitigate some of the side effects associated with FOLITRAX 10MG TABLET 10'S, promoting a more comfortable experience. Adhere strictly to your doctor's prescribed dosage.
  • FOLITRAX 10MG TABLET 10'S may require several weeks or even months to produce noticeable effects. It's crucial to adhere to your prescribed dosage and continue taking the medication consistently, even if you don't see immediate improvements. Do not alter the dosage or discontinue use without consulting your physician.
  • Your doctor will likely schedule regular blood tests to monitor your kidney and liver function, as well as the levels of blood cells in your blood. These tests are vital for detecting any potential adverse effects early on and ensuring the medication is being properly metabolized. Attend all scheduled appointments and discuss any concerns you may have with your doctor.
  • Avoid consuming alcohol while taking FOLITRAX 10MG TABLET 10'S, as it can significantly increase the risk of side effects. Alcohol can interact negatively with the medication and exacerbate potential complications. It is best to abstain from alcohol during the course of treatment.
  • FOLITRAX 10MG TABLET 10'S can potentially harm an unborn baby. Women of childbearing age should avoid pregnancy for at least 6 months after the last dose. Use effective contraception methods during treatment and for the specified period afterward. Consult your doctor for suitable birth control options.
  • Maintain open communication with your healthcare provider throughout your treatment with FOLITRAX 10MG TABLET 10'S. Report any unusual symptoms, side effects, or concerns you may experience. Prompt communication allows for timely adjustments to your treatment plan and ensures the best possible outcome.
  • Store FOLITRAX 10MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage helps maintain the effectiveness and safety of the medication.

FAQs

Can FOLITRAX 10MG TABLET 10'S cause mouth ulcers?

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Yes, FOLITRAX 10MG TABLET 10'S can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Why do I have to take folic acid with FOLITRAX 10MG TABLET 10'S?

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Folic acid is required to make new cells in the body and FOLITRAX 10MG TABLET 10'S decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of FOLITRAX 10MG TABLET 10'S such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Why do I need to take regular blood tests while taking FOLITRAX 10MG TABLET 10'S?

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Regular blood tests will help your doctor to check your response to FOLITRAX 10MG TABLET 10'S and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Can FOLITRAX 10MG TABLET 10'S use make me more prone to infections?

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FOLITRAX 10MG TABLET 10'S may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with FOLITRAX 10MG TABLET 10'S use. If you have an active infection, FOLITRAX 10MG TABLET 10'S should be used with extreme caution.

Can FOLITRAX 10MG TABLET 10'S affect fertility?

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Yes, FOLITRAX 10MG TABLET 10'S may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

What to do if I am planning to become pregnant and my husband is taking FOLITRAX 10MG TABLET 10'S?

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You should avoid pregnancy if your husband is taking FOLITRAX 10MG TABLET 10'S. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

References

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Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. (online) Available from:

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Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. (online) Available from:

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Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 (online) Available from:

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Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. (online) Available from:

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Crohn's & Colitis, UK. Methotrexate [Information Sheet]. (online) Available from:

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CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019]. (online) Available from:

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IPCA LABORATORIES LIMITED

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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