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Content Reviewed By:
Dr. Amit Patel
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
FOLSAFE L TABLET 15'S is generally well-tolerated, but some individuals may experience side effects. These can include: * Nausea * Vomiting * Diarrhea * Constipation * Stomach upset * Loss of appetite * Bloating * Gas * Skin rash * Itching * Allergic reactions (rare)

General Safety and Monitoring
Use under medical supervisionFolsafe L Tablet should be used under the guidance of a qualified healthcare professional, particularly when prescribed for anemia, neuropathy, or documented vitamin deficiency.
FOLSAFE L TABLET is a combination of folic acid and L-Methylfolate, primarily used to treat and prevent folic acid deficiency and is also used in certain types of anemia. It also helps prevent certain birth defects in infants during pregnancy.
The main ingredients in FOLSAFE L TABLET are folic acid and L-Methylfolate.
Common side effects of FOLSAFE L TABLET may include nausea, vomiting, diarrhea, and stomach pain. Consult a doctor if any side effects persist or worsen.
Store FOLSAFE L TABLET at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
Yes, FOLSAFE L TABLET is generally safe for pregnant women as it provides folic acid, which helps prevent birth defects in infants during pregnancy. However, it is important to consult a doctor before taking it.
It is important to consult a doctor before taking FOLSAFE L TABLET with other medications, as it may interact with certain drugs.
The recommended dosage of FOLSAFE L TABLET is usually one tablet once a day, but it should always be taken as directed by a doctor.
Serious side effects of FOLSAFE L TABLET are rare, but may include allergic reactions (such as skin rash, itching, swelling), difficulty breathing, and severe stomach pain. Seek immediate medical attention if you experience any of these symptoms.
FOLSAFE L TABLET works by providing folic acid and L-Methylfolate, which are essential for the production of red blood cells and healthy cell growth in the body.
If you miss a dose of FOLSAFE L TABLET, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
FOLSAFE L TABLET can be taken with or without food. If you experience stomach upset, it is recommended to take it with food.
FOLSAFE L TABLET should be used in children only under the advice of a doctor. The dosage and duration of use will be determined by the doctor.
Alternatives to FOLSAFE L TABLET may include other folic acid supplements and L-Methylfolate supplements. Consult a doctor to determine the most suitable option for you.
The duration for which FOLSAFE L TABLET should be taken will be determined by your doctor. In some cases, it may need to be taken for a long time. Follow your doctor's instructions.
Before taking FOLSAFE L TABLET, tell your doctor about all your medical conditions, allergies, and all the medications you are taking, including vitamins and herbal supplements.
Folsafe L Tablet is generally used as a nutritional supplement in conditions associated with folate and vitamin B12 deficiency. It may be prescribed in certain types of anemia (such as megaloblastic anemia due to deficiency of these vitamins), in individuals with poor dietary intake or malabsorption, and in situations where the body’s requirement for folate and vitamin B12 is increased, such as pregnancy or chronic illness. The exact indication for use should be confirmed with the prescribing doctor.
Folsafe L Tablet should be taken exactly as directed by your doctor. It is usually swallowed whole with water and may be taken with or without food, depending on your doctor’s advice and your tolerance. Do not crush, chew, or break the tablet unless your doctor or pharmacist specifically instructs you to do so. Do not adjust the dose or duration on your own; follow the prescribed regimen and consult your doctor if you miss doses frequently or have difficulty taking the medicine.
Folate supplementation is commonly recommended during pregnancy to support normal fetal development and reduce the risk of neural tube defects. Folsafe L Tablet contains folate-related ingredients and vitamin B12, which may be beneficial in pregnancy when prescribed by a doctor. However, the exact dose and duration must be individualized. Do not start or continue Folsafe L Tablet in pregnancy without consulting your obstetrician or healthcare provider, as excessive or inappropriate dosing may not be advisable.
Folate and vitamin B12 are naturally present in breast milk and are important for the health of both mother and baby. In general, usual supplemental doses of these vitamins are considered compatible with breastfeeding. However, Folsafe L Tablet may contain specific forms and strengths of these nutrients, and safety should be assessed by your doctor based on your clinical condition, nutritional status, and any other medicines you are taking. Always seek medical advice before using this product while breastfeeding.
Folsafe L Tablet is usually well tolerated, but some people may experience mild side effects such as nausea, abdominal discomfort, bloating, loss of appetite, or a feeling of fullness. Headache, dizziness, or a metallic taste in the mouth can also occur. Rarely, allergic reactions such as rash, itching, swelling of the face, lips, or throat, or difficulty breathing may develop and require immediate medical attention. If you notice any unusual or persistent symptoms after starting Folsafe L Tablet, contact your doctor.
Folsafe L Tablet can interact with certain medicines. High-dose folate may reduce the effectiveness of some anticonvulsants, and folate or vitamin B12 supplements may interact with drugs such as methotrexate, chloramphenicol, and some other chemotherapeutic or immunosuppressive agents. To minimize the risk of interactions, inform your doctor and pharmacist about all prescription medicines, over-the-counter products, vitamin supplements, and herbal preparations you are using before starting Folsafe L Tablet. Do not start or stop any medicine without medical guidance.
If you miss a dose of Folsafe L Tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and take the next dose at the regular time. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects without additional benefit. If you frequently forget doses, discuss this with your doctor, who may suggest strategies to improve adherence or adjust your regimen.
Caution is advised in individuals with a history of vitamin B12 deficiency or pernicious anemia, as high folate intake can mask the blood-related signs of B12 deficiency while allowing nerve damage to progress. People with kidney or liver impairment, those with a history of allergic reactions to vitamin preparations, and patients taking medicines that interact with folate or vitamin B12 should also use Folsafe L Tablet only under close medical supervision. Elderly patients and those with long-standing neurological symptoms should be carefully evaluated before and during therapy.
Folsafe L Tablet is not generally known to impair alertness or coordination. However, some individuals may experience dizziness, headache, or fatigue, which could affect the ability to drive or operate machinery safely. If you feel dizzy, unusually tired, or otherwise unwell after taking the tablet, avoid driving, using heavy machinery, or performing tasks that require full concentration until you feel normal again. If such symptoms persist, consult your doctor.
The duration of treatment with Folsafe L Tablet depends on the underlying condition, the severity of deficiency, and your response to therapy. Some people may need it for a defined short course, while others with chronic conditions or ongoing risk factors may require longer-term supplementation as advised by their doctor. Do not stop the medicine abruptly without consulting your healthcare provider, especially if it was prescribed for a documented deficiency or anemia. Regular follow-up and laboratory monitoring may be recommended to decide when to adjust or discontinue therapy.
Folsafe L Tablet is formulated specifically to provide folate-related compounds and vitamin B12, and it may contain these nutrients in doses higher than those found in standard multivitamins. It is not intended to replace a balanced diet or a general multivitamin unless your doctor has recommended it for a particular deficiency or clinical condition. Using it on your own as a routine daily supplement without medical indication may not be necessary and could potentially mask other health issues, such as vitamin B12 deficiency. Always seek professional advice before long-term use.
Folsafe L Tablet 15's is used for folate supplementation, including where conversion of folic acid is impaired; used alongside some antidepressant and prenatal regimens; correcting or preventing vitamin B12 deficiency; supporting nerve function in B12-deficiency-related neuropathy; megaloblastic anaemia due to B12 deficiency; and vitamin B6 supplementation, including where conversion of pyridoxine is impaired. Folsafe L Tablet 15's contains L-methylfolate 1 MG + Methylcobalamin B12 1500 MCG + Pyridoxal 5-PHOSPHATE 0.5 MG. Always use Folsafe L Tablet 15's as advised by your doctor.
Folsafe L Tablet 15's contains L-methylfolate 1 MG + Methylcobalamin B12 1500 MCG + Pyridoxal 5-PHOSPHATE 0.5 MG. It is a active (reduced) form of folate; vitamin B12 (cobalamin) supplement; and active form of vitamin B6.
Commonly reported side effects of Folsafe L Tablet 15's include generally well tolerated; and well tolerated at usual doses. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.
Folsafe L Tablet 15's is listed at Rs. 276.86 on Medkart. Prices can change — check the product page for the current price and pack size.
Like folic acid, it can mask vitamin B12 deficiency while nerve damage progresses — B12 should be assessed; B12 deficiency can mask or coexist with folate deficiency — both should be assessed; and As with pyridoxine, prolonged high-dose use can cause peripheral neuropathy. Tell your doctor about all other medicines you take before starting Folsafe L Tablet 15's.
The dose of Folsafe L Tablet 15's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.
A generic medicine is one with the same active composition as the branded product — for Folsafe L Tablet 15's that is L-methylfolate 1 MG + Methylcobalamin B12 1500 MCG + Pyridoxal 5-PHOSPHATE 0.5 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Folsafe L Tablet 15's.
Folsafe L Tablet 15's contains L-methylfolate 1 MG + Methylcobalamin B12 1500 MCG + Pyridoxal 5-PHOSPHATE 0.5 MG, a active (reduced) form of folate; vitamin B12 (cobalamin) supplement; and active form of vitamin B6. It is used for folate supplementation, including where conversion of folic acid is impaired.
Folsafe L Tablet 15's is listed as not requiring a prescription. Check with your pharmacist if unsure.
Folsafe L Tablet 15's is manufactured by Zydus Lifesciences Limited.
Folsafe L Tablet 15's is supplied as a tablet and is taken by the oral route.
Folsafe L Tablet 15's contains L-methylfolate 1 MG + Methylcobalamin B12 1500 MCG + Pyridoxal 5-PHOSPHATE 0.5 MG. It is used for folate supplementation, including where conversion of folic acid is impaired; used alongside some antidepressant and prenatal regimens; correcting or preventing vitamin B12 deficiency; supporting nerve function in B12-deficiency-related neuropathy; megaloblastic anaemia due to B12 deficiency; and vitamin B6 supplementation, including where conversion of pyridoxine is impaired. The benefit you get depends on the condition your doctor prescribed Folsafe L Tablet 15's for.
Whether Folsafe L Tablet 15's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Folsafe L Tablet 15's on your own.
The timing of Folsafe L Tablet 15's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.
Folsafe L Tablet 15's is listed as not requiring a prescription, but it is still safest to check with a doctor or pharmacist before taking it, especially alongside other medicines.
Do not take Folsafe L Tablet 15's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.
Check with your doctor before drinking alcohol while taking Folsafe L Tablet 15's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.
Store Folsafe L Tablet 15's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.
Folsafe L Tablet 15's is marked discontinued on Medkart and cannot be ordered. Speak to your doctor or pharmacist about alternatives with the same composition.
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Generic medicines at reasonable rates.
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India

MRP
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₹276.86
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