FREXT CR 100MG TABLET 10'S

How FREXT CR 100MG TABLET 10'S Works

• FREXT CR 100MG TABLET 10'S is a medication primarily used to manage and treat epilepsy, a neurological disorder characterized by recurrent seizures. It contains two active ingredients: Pregabalin and Methylcobalamin. Understanding how each component works is crucial to appreciating the overall therapeutic effect of FREXT CR.
• Pregabalin, an analog of gamma-aminobutyric acid (GABA), plays a significant role in reducing neuronal excitability. It binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium ions into nerve terminals. This action has several downstream effects that contribute to its anticonvulsant and analgesic properties. Specifically, it reduces the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals and the initiation and spread of seizures. By decreasing their release, Pregabalin helps to stabilize neuronal activity, reducing the likelihood of seizures and alleviating neuropathic pain.
• Methylcobalamin, a form of vitamin B12, supports nerve health and function. It acts as a cofactor for methionine synthase, an enzyme essential for the synthesis of methionine from homocysteine. Methionine is then converted to S-adenosylmethionine (SAMe), a methyl donor involved in numerous biochemical reactions, including the synthesis of neurotransmitters and the maintenance of myelin, the protective sheath around nerve fibers. Methylcobalamin’s role in these processes helps to improve nerve conduction velocity and overall nerve function. In the context of epilepsy management, maintaining healthy nerve function can help to reduce the frequency and severity of seizures, as well as mitigate some of the neurological complications associated with epilepsy.
• The combination of Pregabalin and Methylcobalamin in FREXT CR 100MG TABLET 10'S offers a synergistic effect. Pregabalin directly reduces neuronal excitability by modulating calcium channel activity and neurotransmitter release, while Methylcobalamin supports the overall health and function of nerves. This dual action helps to control seizures more effectively than either component alone. Additionally, Methylcobalamin can help to counteract some of the potential side effects of Pregabalin, such as peripheral neuropathy, by promoting nerve regeneration and function.
• In summary, FREXT CR 100MG TABLET 10'S works by utilizing Pregabalin to reduce the overactivity of nerves that can lead to seizures and neuropathic pain, while Methylcobalamin supports and maintains the health of these nerves. This comprehensive approach makes it an effective treatment for managing epilepsy and related neurological conditions.

Common side effects of FREXT CR 100MG TABLET may include nausea, vomiting, diarrhea, constipation, stomach pain, loss of appetite, dry mouth, headache, dizziness, drowsiness, insomnia, anxiety, nervousness, tremor, sweating, blurred vision, ringing in the ears (tinnitus), skin rash, itching, and fatigue. Less common but potentially serious side effects can include: Serotonin Syndrome (symptoms may include high fever, agitation, confusion, tremors, muscle spasms), Neuroleptic Malignant Syndrome (symptoms may include high fever, rigid muscles, altered mental status), seizures, abnormal heart rhythm, changes in blood pressure, liver problems (symptoms may include jaundice, dark urine, abdominal pain), low sodium levels in the blood (symptoms may include headache, weakness, muscle cramps), unusual bleeding or bruising, and allergic reactions (symptoms may include rash, itching, swelling, difficulty breathing). Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of FREXT CR 100MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep FREXT CR 100MG TAB 1X10 away from the reach of children and pets.
• Store FREXT CR 100MG TAB 1X10 at room temperature.

• Take FREXT CR 100MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this medication is designed for controlled release and consistent blood levels.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can disrupt the controlled-release mechanism and lead to potential side effects or reduced efficacy.
• FREXT CR 100MG TABLET 10'S is often taken with food to minimize stomach upset. Follow your doctor's recommendations regarding food intake. If you experience persistent nausea or digestive issues, inform your healthcare provider.
• Be consistent with the timing of your doses. Aim to take the tablet at the same time(s) each day to maintain a steady level of medication in your system. This consistency is crucial for optimal therapeutic effects. Setting a daily reminder can be helpful.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Drug interactions can affect how FREXT CR 100MG TABLET 10'S works or increase the risk of side effects. Especially important are other medications affecting the central nervous system.
• Avoid alcohol consumption while taking FREXT CR 100MG TABLET 10'S, as it can intensify sedative effects and potentially lead to dangerous interactions. Alcohol can also interfere with the medication's effectiveness.
• If you miss a dose of FREXT CR 100MG TABLET 10'S, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Store FREXT CR 100MG TABLET 10'S at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Proper storage helps maintain the drug's integrity and effectiveness.
• Do not abruptly stop taking FREXT CR 100MG TABLET 10'S without consulting your doctor, especially if you have been taking it for an extended period. Sudden discontinuation can lead to withdrawal symptoms or a worsening of your condition. Your doctor will guide you on how to safely taper off the medication if needed.
• Be aware of potential side effects, such as drowsiness, dizziness, or gastrointestinal issues. If side effects persist or become bothersome, consult your doctor. They can provide guidance on managing these effects or adjust your treatment plan if necessary.

• FREXT CR 100MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent levels of the medicine in your body. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it may increase the risk of side effects.