GELRAFT ORAL SUSPENSION 150 ML

How GELRAFT ORAL SUSPENSION 150 ML Works

• GELRAFT ORAL SUSPENSION 150 ML is a medication primarily used to treat ulcers in the stomach and esophagus. Its effectiveness stems from its unique mechanism of action, which involves creating a protective barrier over the ulcer and promoting healing. The key ingredient in GELRAFT is sucralfate, a complex salt of sucrose octasulfate and aluminum hydroxide. Here's a detailed breakdown of how GELRAFT works:
• **1. Formation of a Protective Barrier:** When GELRAFT is ingested, sucralfate reacts with the hydrochloric acid present in the stomach. This reaction leads to the polymerization of sucralfate, forming a viscous, sticky substance. This substance adheres strongly to the ulcer site, creating a physical barrier that protects the ulcer from further damage caused by stomach acid, pepsin (a digestive enzyme), and bile acids. Think of it as a bandage that covers the wound inside your stomach or esophagus.
• **2. Selective Binding to Ulcerated Tissue:** Sucralfate has a unique affinity for damaged tissue, particularly ulcerated areas. It preferentially binds to the positively charged proteins that are exposed at the ulcer site. This targeted binding ensures that the protective barrier is formed precisely where it's needed most, maximizing its effectiveness.
• **3. Inhibition of Pepsin Activity:** Pepsin is a powerful enzyme that breaks down proteins and can exacerbate ulcers. Sucralfate has been shown to inhibit the activity of pepsin, reducing its ability to further erode the ulcerated tissue. By reducing pepsin's activity, GELRAFT provides an environment conducive to healing.
• **4. Stimulation of Prostaglandin Production:** Prostaglandins are hormone-like substances that play a crucial role in protecting the stomach lining. They stimulate the secretion of mucus and bicarbonate, which neutralize stomach acid and protect the cells of the stomach lining. Sucralfate can stimulate the production of prostaglandins, further enhancing the protective mechanisms of the stomach.
• **5. Binding of Bile Acids:** Bile acids, which are produced by the liver to aid in fat digestion, can sometimes reflux into the stomach and contribute to ulcer formation. Sucralfate can bind to bile acids, preventing them from irritating the ulcerated tissue.
• In essence, GELRAFT works by creating a multi-faceted defense system that protects the ulcer from the harsh environment of the stomach, inhibits damaging enzymes, and promotes the natural healing processes of the body. It does not reduce the production of acid; instead, it shields the ulcer from its harmful effects, making it an effective treatment for peptic ulcers and other related conditions. The aluminum hydroxide component may also have some antacid properties, further contributing to relief. Always follow your doctor's instructions on how to use GELRAFT oral suspension for best results.

Like all medicines, GELRAFT ORAL SUSPENSION 150 ML can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Constipation * Dry mouth * Nausea * Vomiting * Stomach upset * Indigestion * Skin rash * Itching **Uncommon Side Effects (may affect up to 1 in 100 people):** * Diarrhea * Dizziness * Drowsiness * Back pain **Rare Side Effects (may affect up to 1 in 1,000 people):** * Allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat) * Difficulty swallowing **Other possible side effects:** * Aluminum toxicity (in patients with kidney problems) * Bezoar formation (a hard mass of trapped material in the stomach, especially in patients who are dehydrated or have difficulty emptying their stomach)

• If you miss a dose of GELRAFT ORAL SUSPENSION, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Keep GELRAFT ORAL SUSPENSION 150ML away from the reach of children and pets.
• Store GELRAFT ORAL SUSPENSION 150ML at room temperature.

• Take GELRAFT ORAL SUSPENSION exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration of treatment. This medication is often taken before meals, as directed by your physician, to create a protective layer in the stomach.
• Shake the GELRAFT ORAL SUSPENSION well before each use to ensure that the medication is evenly distributed. This ensures you receive the correct dose and maximizes its effectiveness in treating your condition.
• For optimal results, avoid taking antacids or other medications that affect stomach acidity within 30 minutes before or after taking GELRAFT ORAL SUSPENSION. These medications can interfere with GELRAFT's mechanism of action and reduce its efficacy.
• Inform your doctor about all other medications you are currently taking, including over-the-counter drugs, herbal remedies, and supplements, to prevent potential drug interactions. Certain medications may interact with GELRAFT ORAL SUSPENSION, affecting its effectiveness or increasing the risk of side effects.
• If you experience any persistent or bothersome side effects, such as constipation, dry mouth, or nausea, consult your doctor promptly. While GELRAFT ORAL SUSPENSION is generally well-tolerated, some individuals may experience side effects that require medical attention. Contact your healthcare provider for guidance and management of these side effects.
• Store GELRAFT ORAL SUSPENSION at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use to maintain the medication's stability and prevent degradation. Ensure it is stored out of reach of children and pets.

• It is advisable to take GELRAFT ORAL SUSPENSION 150 ML on an empty stomach, at least 30 minutes before meals. Food may decrease the absorption of sucralfate, reducing its effectiveness. Avoid taking antacids within 30 minutes before or after taking GELRAFT ORAL SUSPENSION 150 ML.