GEMER PL 1MG TABLET 10'S
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GEMER PL 1MG TABLET 10'S
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GEMER PL 1MG TABLET 10'S

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GEMER PL 1MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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65

₹55.25

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About GEMER PL 1MG TABLET 10'S

  • GEMER PL 1MG TABLET is a combination medication designed to help adults manage their type 2 diabetes effectively. It contains three active ingredients: glimepiride, pioglitazone, and metformin. This triple-action formula works synergistically to control blood sugar levels through different mechanisms, offering a comprehensive approach to diabetes management.
  • Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells where it can be used for energy. Pioglitazone is a thiazolidinedione that improves the body's sensitivity to insulin, allowing it to use insulin more effectively. Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity in the muscles. It also slows down the absorption of glucose from the intestines.
  • This combination therapy is typically prescribed when diet, exercise, and single-agent medications are not sufficient to achieve adequate glycemic control. GEMER PL 1MG TABLET helps to lower both fasting and postprandial (after-meal) blood sugar levels. By addressing insulin secretion, insulin resistance, and glucose production, it provides a multifaceted approach to managing blood glucose.
  • It is important to take GEMER PL 1MG TABLET as directed by your doctor. The dosage and timing will depend on your individual needs and other medications you may be taking. Common side effects may include nausea, diarrhea, headache, and hypoglycemia (low blood sugar). It is crucial to monitor blood sugar levels regularly and be aware of the symptoms of hypoglycemia, such as sweating, shakiness, and confusion. Always consult your healthcare provider for any questions or concerns regarding this medication.
  • GEMER PL 1MG TABLET should be used in conjunction with a healthy diet and regular exercise program to achieve optimal blood sugar control and reduce the risk of long-term complications associated with diabetes.

Uses of GEMER PL 1MG TABLET 10'S

  • Treatment of Type 2 Diabetes Mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Combination therapy with sulfonylureas and metformin

How GEMER PL 1MG TABLET 10'S Works

  • GEMER PL 1MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Glimepiride, Pioglitazone, and Metformin. Each component works through different mechanisms to lower blood glucose levels and improve glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into the body's cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps to lower blood sugar levels, especially after meals.
  • Pioglitazone is a thiazolidinedione (TZD) that improves insulin sensitivity in the body. It works by making muscle, fat, and liver cells more responsive to insulin. This allows these cells to take up glucose from the blood more effectively, reducing insulin resistance. Pioglitazone also helps to decrease glucose production in the liver. It impacts gene expression related to glucose and lipid metabolism via activation of PPARγ(peroxisome proliferator-activated receptor gamma).
  • Metformin is a biguanide that works mainly by reducing glucose production in the liver and improving insulin sensitivity. It decreases the amount of glucose the liver releases into the bloodstream and helps muscle cells use insulin more efficiently. Metformin also slows down the absorption of glucose from the intestines after a meal. Metformin primarily activates AMPK(Adenosine Monophosphate-activated Protein Kinase), a central regulator of energy metabolism.
  • In summary, GEMER PL 1MG TABLET 10'S works through a triple-action mechanism: Glimepiride stimulates insulin release, Pioglitazone enhances insulin sensitivity, and Metformin reduces glucose production in the liver and improves insulin utilization. This combination approach helps to maintain stable blood sugar levels throughout the day and night, providing comprehensive control over type 2 diabetes. Always take this medication as prescribed by your doctor to achieve the best possible results.

Side Effects of GEMER PL 1MG TABLET 10'SArrow

Common side effects of GEMER PL 1MG TABLET may include: Hypoglycemia (low blood sugar), Nausea, Diarrhea, Abdominal pain, Vomiting, Taste disturbance. Less common but potentially serious side effects include: Allergic reactions (rash, itching, swelling), Liver problems (jaundice, dark urine), Blood disorders (anemia, low white blood cell count, low platelet count), Lactic acidosis (muscle cramps, rapid breathing), Visual disturbances, Headache, Dizziness, Constipation, Heartburn, Weakness, Fatigue. This is not an exhaustive list. If you experience any unusual symptoms while taking GEMER PL 1MG TABLET, consult your doctor immediately.

Safety Advice for GEMER PL 1MG TABLET 10'SArrow

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Allergies

Consult a Doctor

Do not take Gemer PL 1MG Tablet 10's if you are allergic to it.

Dosage of GEMER PL 1MG TABLET 10'SArrow

  • The recommended dosage of GEMER PL 1MG TABLET 10'S varies depending on individual patient needs, blood glucose levels, and response to treatment. Your physician will determine the appropriate dosage for you. Generally, the starting dose is low and gradually increased to avoid hypoglycemia. It is crucial to follow your doctor’s instructions precisely.
  • Typically, GEMER PL 1MG TABLET 10'S is taken once daily, preferably with the first main meal of the day. This helps to coincide the medication's peak effect with the post-meal rise in blood sugar. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects, particularly hypoglycemia.
  • Regular monitoring of blood glucose levels is essential while taking GEMER PL 1MG TABLET 10'S. This will help your doctor adjust your dosage as needed and ensure that your blood sugar levels are well-controlled. Your doctor may also recommend periodic blood tests to monitor your kidney and liver function.
  • It is important to maintain a healthy lifestyle, including a balanced diet and regular exercise, while taking GEMER PL 1MG TABLET 10'S. This will help to improve your overall health and blood sugar control.
  • Take 'GEMER PL 1MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of GEMER PL 1MG TABLET 10'S?Arrow

  • If you miss a dose of GEMER PL 1MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GEMER PL 1MG TABLET 10'S?Arrow

  • Keep GEMER PL 1MG TAB 1X10 away from the reach of children and pets.
  • Store GEMER PL 1MG TAB 1X10 at room temperature.

Benefits of GEMER PL 1MG TABLET 10'SArrow

  • GEMER PL 1MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise are not enough to control blood sugar levels. It effectively lowers blood glucose levels and helps improve the body's response to insulin. This multi-pronged approach offers several key benefits for managing diabetes:
  • <b>Improved Blood Sugar Control:</b> The primary benefit of GEMER PL 1MG TABLET 10'S is its ability to significantly lower blood sugar levels. By combining three different medications, it targets multiple pathways involved in glucose regulation, leading to more stable and controlled blood sugar throughout the day.
  • <b>Enhanced Insulin Sensitivity:</b> This medication helps improve the body's sensitivity to insulin. Insulin is a hormone that allows glucose to enter cells for energy. In type 2 diabetes, the body becomes resistant to insulin, leading to high blood sugar. GEMER PL 1MG TABLET 10'S helps overcome this resistance, allowing insulin to work more effectively.
  • <b>Reduced Risk of Diabetes Complications:</b> By maintaining healthy blood sugar levels, GEMER PL 1MG TABLET 10'S can help reduce the risk of long-term complications associated with diabetes. These complications can include cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and foot problems.
  • <b>Convenient Once-Daily Dosage:</b> GEMER PL 1MG TABLET 10'S is typically taken once daily, making it a convenient option for managing diabetes. This can improve adherence to the medication regimen and simplify diabetes management.
  • <b>Weight Management:</b> Some components of GEMER PL 1MG TABLET 10'S may help with weight management, which is often a challenge for individuals with type 2 diabetes. Maintaining a healthy weight can further improve blood sugar control and reduce the risk of complications.
  • <b>Improved Lipid Profile:</b> This medication can also have a positive impact on lipid profiles, such as cholesterol and triglycerides. This is important because individuals with diabetes are at an increased risk of cardiovascular disease.
  • <b>Overall Improved Quality of Life:</b> By effectively managing blood sugar levels and reducing the risk of complications, GEMER PL 1MG TABLET 10'S can contribute to an overall improvement in the quality of life for individuals with type 2 diabetes. This includes increased energy levels, reduced fatigue, and improved overall well-being.
  • <b>Comprehensive Glycemic Control:</b> The combination of Glimepiride, Metformin, and Pioglitazone addresses multiple aspects of blood sugar regulation, offering more comprehensive glycemic control compared to single-agent therapy.
  • <b>Reduced Risk of Hypoglycemia Compared to Sulfonylureas Alone:</b> While Glimepiride can cause hypoglycemia, the combination with Metformin and Pioglitazone may reduce the risk of low blood sugar compared to taking Glimepiride (a sulfonylurea) alone. However, it is still important to monitor blood sugar levels regularly and be aware of the symptoms of hypoglycemia.

How to use GEMER PL 1MG TABLET 10'SArrow

  • GEMER PL 1MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It is crucial to take this medication exactly as prescribed by your doctor. Typically, it is taken orally, once daily, preferably with your first main meal to minimize the risk of stomach upset and to aid in consistent absorption. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect how the medication is released into your system.
  • The dosage of GEMER PL 1MG TABLET 10'S will vary depending on your individual needs, blood sugar levels, and response to treatment. Your doctor will determine the appropriate dosage for you. It is important to monitor your blood sugar regularly, as directed by your physician or diabetes educator, especially when starting this medication or if your dosage is adjusted. This will help ensure that the medication is working effectively and will allow your doctor to make any necessary changes to your treatment plan.
  • While taking GEMER PL 1MG TABLET 10'S, it is essential to follow a healthy diet and exercise regularly. This will help improve your blood sugar control and overall health. Avoid consuming excessive amounts of alcohol, as it can interact with this medication and increase the risk of side effects, such as hypoglycemia (low blood sugar). Be aware of the symptoms of hypoglycemia, which may include shakiness, sweating, dizziness, and confusion. If you experience these symptoms, consume a fast-acting source of sugar, such as glucose tablets or fruit juice, and contact your doctor immediately.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with GEMER PL 1MG TABLET 10'S. This is particularly important for medications that affect blood sugar levels, such as other diabetes medications, corticosteroids, or thyroid hormones. Do not stop taking this medication without consulting your doctor, even if you feel well, as abruptly discontinuing it can cause your blood sugar to rise. Regular check-ups with your doctor are important to monitor your condition and adjust your treatment plan as needed.

Quick Tips for GEMER PL 1MG TABLET 10'SArrow

  • Take GEMER PL 1MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key for optimal blood sugar control. Missing doses can lead to fluctuations in blood sugar levels, increasing the risk of complications. Set a daily reminder if needed.
  • GEMER PL 1MG TABLET 10'S is most effective when taken with meals. This helps to regulate the absorption of glucose and prevent sudden spikes in blood sugar. Follow the dietary recommendations provided by your doctor or a registered dietitian. A balanced diet, rich in fiber, whole grains, and lean protein, is crucial for managing diabetes and maximizing the benefits of GEMER PL.
  • Regular blood glucose monitoring is essential while taking GEMER PL 1MG TABLET 10'S. Keep a log of your blood sugar levels and share it with your doctor during check-ups. This helps them assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. Familiarize yourself with the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar), and know how to respond accordingly.
  • Be aware of potential side effects of GEMER PL 1MG TABLET 10'S, such as hypoglycemia, nausea, and weight gain. If you experience any bothersome or persistent side effects, inform your doctor promptly. Hypoglycemia can be particularly dangerous, so always carry a source of fast-acting glucose, such as glucose tablets or fruit juice, in case your blood sugar drops too low. Learn to recognize the early warning signs of low blood sugar, such as shakiness, sweating, and confusion.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting GEMER PL 1MG TABLET 10'S. Certain medications can interact with GEMER PL and affect its effectiveness or increase the risk of side effects. This includes over-the-counter drugs, vitamins, and herbal products. Always keep your healthcare provider informed about any changes to your medication regimen.

Food Interactions with GEMER PL 1MG TABLET 10'SArrow

  • GEMER PL 1MG TABLET 10'S should be taken as directed by your doctor. Generally, it is recommended to take it with or immediately after a meal to help prevent stomach upset. Consistent timing with meals is important for maintaining stable blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar).

FAQs

What is GEMER PL 1MG TABLET 10'S used for?Arrow

GEMER PL 1MG TABLET 10'S is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does GEMER PL 1MG TABLET 10'S work?Arrow

GEMER PL 1MG TABLET 10'S is a combination of three medicines: Glimepiride, Pioglitazone and Metformin. Glimepiride is a sulfonylurea which lowers blood glucose by increasing the release of insulin from the pancreas. Pioglitazone is a thiazolidinedione which improves insulin sensitivity. Metformin is a biguanide which decreases glucose production in the liver and improves insulin sensitivity.

What are the common side effects of GEMER PL 1MG TABLET 10'S?Arrow

The common side effects of GEMER PL 1MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness.

Is GEMER PL 1MG TABLET 10'S safe during pregnancy?Arrow

The safety of GEMER PL 1MG TABLET 10'S during pregnancy is not established. Therefore, it should not be used during pregnancy unless considered clearly necessary by the doctor.

Is GEMER PL 1MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether GEMER PL 1MG TABLET 10'S is excreted in human milk. Therefore, it should not be used during breastfeeding.

Can GEMER PL 1MG TABLET 10'S cause weight gain?Arrow

Yes, GEMER PL 1MG TABLET 10'S can cause weight gain.

What is the dosage of GEMER PL 1MG TABLET 10'S?Arrow

The dosage of GEMER PL 1MG TABLET 10'S will be determined by the doctor. The dosage will be based on your medical condition and response to treatment.

What happens if I miss a dose of GEMER PL 1MG TABLET 10'S?Arrow

If you miss a dose of GEMER PL 1MG TABLET 10'S, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can GEMER PL 1MG TABLET 10'S interact with other medications?Arrow

Yes, GEMER PL 1MG TABLET 10'S can interact with other medications. Therefore, it is important to tell your doctor about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.

Should I avoid alcohol while taking GEMER PL 1MG TABLET 10'S?Arrow

Drinking alcohol while taking GEMER PL 1MG TABLET 10'S can lower your blood sugar levels. Therefore, you should avoid drinking alcohol while taking GEMER PL 1MG TABLET 10'S.

How to store GEMER PL 1MG TABLET 10'S?Arrow

Store GEMER PL 1MG TABLET 10'S at room temperature, away from heat and moisture. Keep out of reach of children.

Can GEMER PL 1MG TABLET 10'S cause hypoglycemia?Arrow

Yes, GEMER PL 1MG TABLET 10'S can cause hypoglycemia (low blood sugar), especially if you are taking other antidiabetic medications or skipping meals.

What to do in case of an overdose of GEMER PL 1MG TABLET 10'S?Arrow

In case of an overdose of GEMER PL 1MG TABLET 10'S, contact a doctor immediately or go to the nearest hospital.

Is GEMER PL 1MG TABLET 10'S safe for people with kidney disease?Arrow

GEMER PL 1MG TABLET 10'S should be used with caution in people with kidney disease. The dosage may need to be adjusted according to kidney function.

Is GEMER PL 1MG TABLET 10'S safe for people with heart disease?Arrow

GEMER PL 1MG TABLET 10'S should be used with caution in people with heart disease, as it may increase the risk of heart failure.

References

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FDA - AMARYL (glimepiride) tablets. Prescribing information. Describes usage, dosage, side effects, and interactions. Though this refers to Amaryl, glimepiride is the active ingredient in Gemer PL.

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DrugBank - Glimepiride. Detailed chemical and pharmacological information about glimepiride.

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National Center for Biotechnology Information (NCBI) - Glimepiride: Evidence-Based Facts, Comparisons and Prescribing Recommendations. A peer-reviewed article providing evidence-based information on glimepiride.

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National Center for Biotechnology Information (NCBI) - Glimepiride. LiverTox resource providing information on glimepiride's potential hepatotoxicity.

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FDA - Metformin Hydrochloride Tablets, USP. Prescribing information for metformin hydrochloride, an ingredient sometimes combined with glimepiride.

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DrugBank - Metformin. Detailed chemical and pharmacological information about Metformin.

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Marketer / Manufacturer Details

SUN PHARMACEUTICAL INDUSTRIES LTD

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