GEMER SITA IR 50MG/1000MG/2MG TABLET 10'S

How GEMER SITA IR 50MG/1000MG/2MG TABLET 10'S Works

• GEMER SITA IR 50MG/1000MG/2MG TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It brings together the complementary actions of three active ingredients: Sitagliptin, Metformin, and Glimepiride, each working through distinct mechanisms to achieve comprehensive glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood sugar levels are high and suppress glucagon secretion from the pancreas, which reduces glucose production by the liver. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to increased insulin secretion in response to meals and decreased glucagon secretion, both of which help lower blood sugar levels. Sitagliptin's action is glucose-dependent, meaning it primarily works when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin is a biguanide that works primarily by reducing glucose production in the liver. The liver is a major source of glucose in the body, and in individuals with type 2 diabetes, it often produces excessive amounts of glucose. Metformin inhibits hepatic glucose production by suppressing gluconeogenesis (the formation of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. This reduces insulin resistance, a common problem in type 2 diabetes. Metformin may also slow down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effects. Unlike some other diabetes medications, Metformin does not stimulate insulin secretion directly, so it carries a lower risk of causing hypoglycemia when used alone.
• Glimepiride is a sulfonylurea that stimulates the release of insulin from the beta cells in the pancreas. It works by binding to specific receptors on the beta cells, which triggers a series of intracellular events leading to the secretion of insulin. Glimepiride is a potent insulin secretagogue, meaning it can effectively lower blood sugar levels by increasing insulin release. However, because it directly stimulates insulin secretion, there is a risk of hypoglycemia, particularly if meals are skipped or if the dose is too high. Glimepiride also appears to improve insulin sensitivity to some extent. The combined action of Sitagliptin, Metformin and Glimepiride addresses multiple aspects of type 2 diabetes, improving insulin secretion and sensitivity and reducing glucose production. Regular blood sugar monitoring and adherence to diet and exercise recommendations are important for maximizing the benefits of this medication.

Common side effects of GEMER SITA IR 50MG/1000MG/2MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, and upper respiratory tract infection. Less common but potentially serious side effects could involve lactic acidosis, pancreatitis, severe allergic reactions (rash, itching, swelling), liver problems, and blood disorders. Consult your doctor immediately if you experience persistent or severe side effects.

• If you miss a dose of GEMER SITA IR 50MG/1000MG/2MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.

• Keep GEMER SITA IR 50/1000/2MG TAB 1X10 away from the reach of children and pets.
• Store GEMER SITA IR 50/1000/2MG TAB 1X10 at room temperature.

• Take GEMER SITA IR as prescribed by your doctor, usually once or twice daily with meals to avoid stomach upset. Consistent timing is key for optimal blood sugar control.
• GEMER SITA IR combines three medications to effectively lower blood sugar. Continue following your diet and exercise plan while taking this medication for best results. Do not discontinue medicine without consulting with doctor.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. Share these readings with your doctor to help them adjust your dosage of GEMER SITA IR if needed.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, or confusion. Carry a source of quick-acting sugar, like glucose tablets or juice, with you at all times.
• Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with GEMER SITA IR. Pay special attention to medications that also lower blood sugar, as combining them can increase your risk of hypoglycemia.