GENXVAST F TABLET 10'S
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GENXVAST F TABLET 10'S

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GENXVAST F TABLET 10'S

By HETERO DRUGS LIMITED

MRP

46.5

₹39.52

15.01 % OFF

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About GENXVAST F TABLET 10'S

  • GENXVAST F TABLET 10'S is a combination medication formulated to effectively manage cholesterol levels and reduce the risk of cardiovascular diseases. It combines two active ingredients, Atorvastatin and Fenofibrate, working synergistically to address multiple lipid parameters.
  • Atorvastatin belongs to a class of drugs known as statins. It primarily functions by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol synthesis within the liver. By reducing cholesterol production, Atorvastatin lowers LDL-cholesterol (bad cholesterol) levels in the blood. Additionally, it can modestly increase HDL-cholesterol (good cholesterol) and lower triglyceride levels.
  • Fenofibrate, on the other hand, is a fibric acid derivative. Its main mechanism of action involves activating peroxisome proliferator-activated receptor alpha (PPARα). This activation leads to increased breakdown and elimination of triglycerides from the blood, as well as an increase in HDL-cholesterol. Fenofibrate also has a beneficial effect on LDL particle size, converting small, dense LDL particles (which are more atherogenic) into larger, more buoyant LDL particles.
  • The combination of Atorvastatin and Fenofibrate in GENXVAST F TABLET 10'S provides a comprehensive approach to lipid management. It effectively lowers LDL-cholesterol, triglycerides, and increases HDL-cholesterol, addressing multiple aspects of dyslipidemia. This makes it a valuable treatment option for patients at high risk of cardiovascular events, such as those with diabetes, metabolic syndrome, or a history of heart disease.
  • GENXVAST F TABLET 10'S should be used in conjunction with a healthy lifestyle, including a balanced diet, regular exercise, and smoking cessation. It is crucial to follow your doctor's instructions regarding dosage and administration. Regular monitoring of liver function and lipid levels is also recommended while taking this medication.

Uses of GENXVAST F TABLET 10'S

  • Treatment of High Cholesterol
  • Treatment of Mixed Dyslipidemia
  • Lowering Triglycerides
  • Prevention of Cardiovascular Diseases
  • Prevention of Stroke
  • Prevention of Heart Attack

How GENXVAST F TABLET 10'S Works

  • GENXVAST F TABLET 10'S is a combination medication designed to manage cholesterol levels and reduce the risk of cardiovascular diseases. It combines two active ingredients: Atorvastatin and Fenofibrate, each working through different mechanisms to achieve comprehensive lipid control.
  • Atorvastatin belongs to a class of drugs called statins, or HMG-CoA reductase inhibitors. It primarily works by blocking the action of HMG-CoA reductase, an enzyme crucial for cholesterol production in the liver. By inhibiting this enzyme, Atorvastatin reduces the synthesis of cholesterol, particularly low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol. Lowering LDL cholesterol helps prevent the buildup of plaque in the arteries, reducing the risk of atherosclerosis, heart attack, and stroke.
  • Fenofibrate, on the other hand, is a fibric acid derivative. It primarily works by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activation leads to increased breakdown and elimination of triglyceride-rich lipoproteins from the bloodstream. It also helps in increasing the levels of high-density lipoprotein (HDL) cholesterol, known as 'good' cholesterol. By reducing triglycerides and increasing HDL cholesterol, Fenofibrate complements the action of Atorvastatin in improving overall lipid profile.
  • The synergistic action of Atorvastatin and Fenofibrate in GENXVAST F TABLET 10'S provides a comprehensive approach to managing dyslipidemia (abnormal blood lipid levels). Atorvastatin primarily targets LDL cholesterol, while Fenofibrate focuses on triglycerides and HDL cholesterol. This combination is particularly beneficial for individuals with mixed hyperlipidemia, characterized by elevated LDL cholesterol, elevated triglycerides, and low HDL cholesterol levels.
  • By effectively managing lipid levels, GENXVAST F TABLET 10'S helps to reduce the risk of cardiovascular events such as heart attack, stroke, and peripheral artery disease. Regular use of this medication, in conjunction with a healthy diet and lifestyle modifications, can significantly improve cardiovascular health.
  • It's important to note that GENXVAST F TABLET 10'S should be taken as prescribed by a healthcare professional. The dosage and duration of treatment will depend on individual lipid levels, overall health status, and response to therapy. Regular monitoring of lipid levels and liver function is recommended during treatment with this medication.

Side Effects of GENXVAST F TABLET 10'SArrow

GENXVAST F TABLET 10'S, like all medications, can cause side effects, although not everyone experiences them. Common side effects may include headache, muscle pain or weakness, stomach upset, nausea, diarrhea, constipation, and gas. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, or persistent fatigue), muscle damage (rhabdomyolysis, indicated by severe muscle pain and weakness), allergic reactions (rash, itching, swelling, difficulty breathing), and increased blood sugar levels. Other reported side effects are dizziness, blurred vision, difficulty sleeping (insomnia), and skin reactions. This is not an exhaustive list, and it's important to consult your doctor or pharmacist for a complete list and to report any unusual symptoms.

Safety Advice for GENXVAST F TABLET 10'SArrow

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Allergies

Allergies

Do not use GENXVAST F TABLET 10'S if you are allergic to it.

Dosage of GENXVAST F TABLET 10'SArrow

  • The recommended dosage of GENXVAST F TABLET 10'S is typically one tablet daily, taken orally with water. However, the precise dosage and timing should be determined by your physician based on your individual medical condition, cholesterol levels, and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage. Do not exceed the prescribed dose or discontinue the medication without consulting your healthcare provider, as this could negatively impact your health.
  • GENXVAST F TABLET 10'S can be taken with or without food, but consistency in timing is advisable. Taking the tablet at the same time each day helps maintain a steady level of the medication in your bloodstream, which can improve its effectiveness. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
  • Before starting GENXVAST F TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications can interact with GENXVAST F TABLET 10'S, potentially affecting its efficacy or increasing the risk of side effects. Regular monitoring of your liver function and lipid levels may be necessary while taking this medication to ensure its safety and effectiveness. Take 'GENXVAST F TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of GENXVAST F TABLET 10'S?Arrow

  • If you miss a dose of GENXVAST F TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GENXVAST F TABLET 10'S?Arrow

  • Keep GENXVAST F TAB 1X10 away from the reach of children and pets.
  • Store GENXVAST F TAB 1X10 at room temperature.

Benefits of GENXVAST F TABLET 10'SArrow

  • GENXVAST F Tablet 10'S offers a dual-action approach to managing cholesterol and reducing the risk of cardiovascular events. This combination medication contains both a statin (atorvastatin) and a fibrate (fenofibrate), providing comprehensive lipid management.
  • Atorvastatin, the statin component, primarily works by inhibiting the enzyme HMG-CoA reductase in the liver. This enzyme is crucial for cholesterol production. By blocking this enzyme, atorvastatin effectively lowers LDL-cholesterol (bad cholesterol) levels in the blood. Lowering LDL-cholesterol is vital for preventing the buildup of plaque in the arteries, a process known as atherosclerosis. Atherosclerosis can lead to heart attacks, strokes, and other cardiovascular complications. Statins like atorvastatin are also known to modestly increase HDL-cholesterol (good cholesterol) levels, which further contributes to cardiovascular protection.
  • Fenofibrate, the fibrate component, primarily works by activating peroxisome proliferator-activated receptor alpha (PPARα). This activation leads to a cascade of effects that improve lipid profiles. Fenofibrate significantly lowers triglyceride levels, another type of fat in the blood that contributes to cardiovascular risk. Elevated triglycerides are often associated with insulin resistance and metabolic syndrome. In addition to lowering triglycerides, fenofibrate also increases HDL-cholesterol levels, further enhancing its cardioprotective effects. It also helps in reducing the levels of small, dense LDL particles, which are considered more atherogenic than larger LDL particles.
  • The combination of atorvastatin and fenofibrate in GENXVAST F Tablet 10'S is particularly beneficial for individuals with mixed dyslipidemia, a condition characterized by high LDL-cholesterol, high triglycerides, and low HDL-cholesterol. By addressing all three lipid abnormalities, this medication provides a more comprehensive approach to lipid management than either a statin or a fibrate alone.
  • GENXVAST F Tablet 10'S helps in preventing cardiovascular diseases. By effectively managing cholesterol and triglyceride levels, it reduces the risk of heart attacks, strokes, angina (chest pain), and peripheral artery disease. This medicine is prescribed to people who are at high risk of cardiovascular events, particularly those with multiple risk factors such as high blood pressure, diabetes, smoking, and a family history of heart disease.
  • Beyond lipid management, some studies suggest that fenofibrate may have additional benefits, such as reducing inflammation and improving insulin sensitivity. These effects can further contribute to overall cardiovascular health and reduce the risk of diabetes-related complications.
  • GENXVAST F Tablet 10'S is an effective treatment for hyperlipidemia and hypertriglyceridemia, thereby preventing serious health issues.

How to use GENXVAST F TABLET 10'SArrow

  • GENXVAST F TABLET 10'S should be taken orally, exactly as prescribed by your doctor. Typically, it's taken once daily, preferably in the evening, but follow your doctor's specific instructions regarding timing. Consistency is key; try to take it at the same time each day to maintain a steady level of medication in your body. This helps ensure the medication works effectively.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist; they may be able to suggest alternative formulations or techniques to make it easier.
  • GENXVAST F TABLET 10'S can be taken with or without food, but it's important to maintain a consistent dietary pattern. Avoid consuming large amounts of grapefruit or grapefruit juice, as it can interact with the medication and increase the risk of side effects. Also, limit your alcohol intake, as alcohol can worsen certain side effects and may interfere with the medication's effectiveness.
  • Continue taking GENXVAST F TABLET 10'S even if you feel well. Many people with high cholesterol or triglyceride levels don't experience any symptoms, so it's crucial to stick to your prescribed treatment plan. Do not stop taking the medication without consulting your doctor, as your cholesterol levels may increase.
  • If you miss a dose of GENXVAST F TABLET 10'S, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you have any questions about what to do if you miss a dose, ask your doctor or pharmacist.

Quick Tips for GENXVAST F TABLET 10'SArrow

  • Take GENXVAST F TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, even if you feel better. Consistency is key to its effectiveness in managing cholesterol and triglyceride levels.
  • GENXVAST F TABLET 10'S is typically taken once daily in the evening. This is because cholesterol production in the body is higher at night. Following a consistent schedule will help you remember to take your medication and maximize its benefits.
  • Avoid consuming large amounts of grapefruit or grapefruit juice while taking GENXVAST F TABLET 10'S. Grapefruit can interfere with the metabolism of the drug, potentially increasing the risk of side effects. Consult your doctor or pharmacist for more information.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting GENXVAST F TABLET 10'S. Drug interactions can occur, affecting the effectiveness of the medication or increasing the risk of adverse effects. This includes over-the-counter medications.
  • If you experience any unusual muscle pain, tenderness, or weakness while taking GENXVAST F TABLET 10'S, contact your doctor immediately. These could be signs of a rare but serious side effect called myopathy or rhabdomyolysis. Early detection and treatment can prevent serious complications.
  • Maintain a healthy lifestyle while taking GENXVAST F TABLET 10'S. This includes following a balanced diet low in saturated and trans fats, exercising regularly, and avoiding smoking. These lifestyle changes can enhance the effectiveness of the medication and improve your overall cardiovascular health.

Food Interactions with GENXVAST F TABLET 10'SArrow

  • GENXVAST F TABLET 10'S can be taken with or without food. However, it is important to take it at the same time each day for consistent absorption and effectiveness. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it can increase the level of the drug in your body and potentially lead to side effects. Consult your doctor or pharmacist for further guidance on specific dietary restrictions.

FAQs

What is GENXVAST F Tablet 10'S and what is it used for?Arrow

GENXVAST F Tablet 10'S is a combination medicine primarily used to lower high levels of cholesterol and triglycerides, reducing the risk of heart diseases.

What are the active ingredients in GENXVAST F Tablet 10'S?Arrow

GENXVAST F Tablet 10'S typically contains Atorvastatin (a statin) and Fenofibrate.

What are the common side effects of GENXVAST F Tablet 10'S?Arrow

Common side effects may include muscle pain, abdominal pain, nausea, headache, and elevated liver enzymes.

Is GENXVAST F Tablet 10'S safe for pregnant women?Arrow

No, GENXVAST F Tablet 10'S is generally not recommended during pregnancy as it can harm the developing fetus.

How should I store GENXVAST F Tablet 10'S?Arrow

Store it at room temperature, away from direct sunlight and moisture. Keep out of reach of children.

Can GENXVAST F Tablet 10'S be taken with or without food?Arrow

It is generally recommended to take it with food, but follow your doctor's instructions.

What happens if I miss a dose of GENXVAST F Tablet 10'S?Arrow

Take the missed dose as soon as you remember. However, if it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can GENXVAST F Tablet 10'S interact with other medications?Arrow

Yes, GENXVAST F Tablet 10'S can interact with certain medications, such as anticoagulants, some antifungals, and antibiotics. Tell your doctor about all the medications you are taking.

What should I tell my doctor before using GENXVAST F Tablet 10'S?Arrow

Tell your doctor about all your medical conditions, allergies, and all the medications you are taking.

Can GENXVAST F Tablet 10'S cause liver damage?Arrow

In rare cases, GENXVAST F Tablet 10'S can cause liver damage. Your doctor may monitor your liver function regularly during treatment.

Can GENXVAST F Tablet 10'S cause muscle pain?Arrow

Yes, GENXVAST F Tablet 10'S can cause muscle pain or weakness. Tell your doctor if you experience unexplained muscle pain.

Is it safe to drink alcohol with GENXVAST F Tablet 10'S?Arrow

Consuming alcohol with GENXVAST F Tablet 10'S may increase the risk of liver problems. Consult your doctor before drinking alcohol.

How long does it take for GENXVAST F Tablet 10'S to work?Arrow

It may take a few weeks for GENXVAST F Tablet 10'S to show improvement in cholesterol and triglyceride levels.

Can I stop taking GENXVAST F Tablet 10'S once my cholesterol levels are normal?Arrow

Do not stop taking GENXVAST F Tablet 10'S without consulting your doctor. Stopping the medication may cause your cholesterol levels to rise again.

Can GENXVAST F Tablet 10'S be used in children?Arrow

GENXVAST F Tablet 10'S is generally not recommended for children unless specifically directed by a doctor.

References

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DrugBank: Tenofovir alafenamide

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DrugBank: Emtricitabine

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FDA Label: GENVOYA (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) tablets, for oral use

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PubMed: Search engine for biomedical literature.

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European Medicines Agency (EMA): Genvoya assessment report

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HETERO DRUGS LIMITED

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India

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