GLIMICURE M 4MG TABLET 15'S
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GLIMICURE M 4MG TABLET 15'SGLIMICURE M 4MG TABLET 15'SGLIMICURE M 4MG TABLET 15'S
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GLIMICURE M 4MG TABLET 15'S

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GLIMICURE M 4MG TABLET 15'S

By HBC LIFESCIENCES PRIVATE LIMITED

MRP

206.3

₹175.36

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About GLIMICURE M 4MG TABLET 15'S

  • GLIMICURE M 4MG TABLET 15'S is a combination medicine used to treat type 2 diabetes mellitus in adults. It combines two oral antidiabetic drugs: Glimepiride and Metformin. By improving insulin sensitivity and lowering blood glucose levels, it helps control blood sugar effectively.
  • Glimepiride is a sulfonylurea that works by stimulating the release of insulin from the pancreas. This helps lower blood glucose levels, particularly after meals. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in the body's tissues. This allows cells to utilize glucose more efficiently, further lowering blood sugar levels.
  • This combination offers a dual-pronged approach to managing blood sugar, addressing both insulin secretion and insulin resistance. It is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels. GLIMICURE M 4MG TABLET 15'S is usually taken once or twice daily with meals, as directed by your doctor. It's crucial to follow your doctor's instructions regarding dosage and timing to achieve optimal results and minimize potential side effects. Common side effects may include nausea, diarrhea, and abdominal discomfort. Hypoglycemia (low blood sugar) is also a potential risk, especially when taken with other diabetes medications or if meals are skipped. Regular monitoring of blood sugar levels is essential while taking this medication.
  • Before starting GLIMICURE M 4MG TABLET 15'S, inform your doctor about any other medical conditions you have, especially kidney or liver problems. Also, disclose all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. This medication is not recommended for pregnant or breastfeeding women. A healthy diet, regular exercise, and adherence to your doctor's instructions are crucial for effectively managing diabetes and preventing long-term complications. Store in a cool, dry place away from direct sunlight and moisture.

Uses of GLIMICURE M 4MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control along with diet and exercise
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Reducing the risk of cardiovascular complications in patients who have both type 2 diabetes and heart disease

How GLIMICURE M 4MG TABLET 15'S Works

  • GLIMICURE M 4MG TABLET 15'S is a combination medication designed to manage type 2 diabetes mellitus. It contains two active ingredients: Glimipiride and Metformin. These components work synergistically to lower blood glucose levels through different mechanisms.
  • Glimipiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the release of insulin from the beta cells in the pancreas. Insulin is a hormone that helps glucose (sugar) move from the blood into the body's cells, where it can be used for energy. By increasing insulin secretion, Glimipiride helps lower blood sugar levels, particularly after meals.
  • Metformin, on the other hand, is a biguanide. Its primary action is to reduce glucose production in the liver. The liver is a major source of glucose in the body, and Metformin helps to decrease the amount of glucose released into the bloodstream. Additionally, Metformin improves the body's sensitivity to insulin, allowing cells to use insulin more effectively. This means that the cells are better able to take up glucose from the blood, further contributing to lower blood sugar levels.
  • The combination of Glimipiride and Metformin addresses multiple aspects of type 2 diabetes. Glimipiride boosts insulin secretion to handle post-meal glucose spikes, while Metformin reduces hepatic glucose output and improves insulin sensitivity for overall blood sugar control. This dual action helps to maintain stable blood glucose levels throughout the day.
  • Specifically, Glimipiride binds to the sulfonylurea receptor on pancreatic beta cells. This binding triggers a cascade of events that ultimately lead to the exocytosis (release) of insulin granules. The released insulin then facilitates glucose uptake by muscle and adipose tissue, lowering blood glucose.
  • Metformin's mechanism is more complex and not fully understood, but it is known to activate an enzyme called AMP-activated protein kinase (AMPK). AMPK activation in the liver reduces glucose production by inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin enhances glucose uptake and utilization in peripheral tissues such as muscle by increasing the number and activity of glucose transporters (GLUTs).
  • In summary, GLIMICURE M 4MG TABLET 15'S effectively manages blood sugar by using Glimipiride to stimulate insulin release and Metformin to reduce glucose production and improve insulin sensitivity. This combined approach provides a comprehensive strategy for controlling hyperglycemia in patients with type 2 diabetes, helping to minimize the risk of long-term complications associated with elevated blood sugar levels.

Side Effects of GLIMICURE M 4MG TABLET 15'SArrow

Possible side effects of GLIMICURE M 4MG TABLET may include: * Hypoglycemia (low blood sugar): This is the most common side effect, characterized by symptoms like shakiness, sweating, anxiety, blurred vision, rapid heartbeat, headache, and confusion. * Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite can occur. * Metallic taste * Skin reactions: Rash, itching, redness, and hives are possible. * Headache * Dizziness * Visual disturbances: Blurred vision can occur, especially at the start of treatment. * Changes in blood cell counts: In rare cases, this medication can affect blood cell production. * Liver problems: Liver dysfunction and jaundice (yellowing of the skin and eyes) are rare but serious side effects. * Weight gain * Weakness * Fatigue * Fluid retention/Edema This is not an exhaustive list, and other side effects may occur. It's important to contact your doctor immediately if you experience any unusual or severe symptoms while taking this medication.

Safety Advice for GLIMICURE M 4MG TABLET 15'SArrow

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Dosage of GLIMICURE M 4MG TABLET 15'SArrow

  • The recommended dosage of 'GLIMICURE M 4MG TABLET 15'S' varies depending on individual patient needs, blood glucose levels, and response to treatment. It is crucial to follow your doctor's instructions precisely. Typically, the starting dose is low and gradually increased to achieve optimal glycemic control.
  • The usual starting dose for adults is 1mg to 2mg of glimepiride (the active ingredient in 'GLIMICURE M 4MG TABLET 15'S') once daily, taken with breakfast or the first main meal. The dosage may be adjusted by your doctor every 1-2 weeks based on your blood glucose readings. The maximum recommended daily dose is generally 8mg.
  • Metformin, another active ingredient, is usually started at a dose of 500mg once or twice daily with meals. This may also be gradually increased under medical supervision to a maximum of 2000mg per day, divided into multiple doses.
  • It's essential to monitor your blood glucose levels regularly as directed by your healthcare provider. This will help determine if the dosage needs adjustment. Factors like diet, exercise, and other medications can influence your blood sugar control, so inform your doctor about any changes in these areas.
  • If you miss a dose of 'GLIMICURE M 4MG TABLET 15'S', take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Take 'GLIMICURE M 4MG TABLET 15'S' only as per the prescription by your physician only.

What if I miss my dose of GLIMICURE M 4MG TABLET 15'S?Arrow

  • If you miss a dose of GLIMICURE M 4MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLIMICURE M 4MG TABLET 15'S?Arrow

  • Keep GLIMICURE M 4MG TAB 1X15 away from the reach of children and pets.
  • Store GLIMICURE M 4MG TAB 1X15 at room temperature.

Benefits of GLIMICURE M 4MG TABLET 15'SArrow

  • GLIMICURE M 4MG TABLET 15'S is a combination medicine primarily used to manage type 2 diabetes mellitus. Its dual-action mechanism helps lower blood sugar levels effectively, providing comprehensive glycemic control.
  • The primary benefit of GLIMICURE M 4MG TABLET 15'S lies in its ability to improve insulin sensitivity. Metformin, one of its key components, reduces insulin resistance, allowing your body to use insulin more efficiently. This, in turn, helps lower blood glucose levels.
  • Gliclazide, the other active ingredient, stimulates the release of insulin from the pancreas. This insulin secretion helps in managing post-meal blood sugar spikes, ensuring stable blood sugar levels throughout the day.
  • By effectively controlling blood sugar, GLIMICURE M 4MG TABLET 15'S reduces the risk of long-term complications associated with diabetes, such as kidney damage (nephropathy), nerve damage (neuropathy), eye damage (retinopathy), and cardiovascular problems.
  • Regular use of this medication helps maintain stable HbA1c levels. HbA1c is a measure of average blood sugar control over the past 2-3 months. Keeping HbA1c within the target range is crucial for preventing diabetic complications.
  • GLIMICURE M 4MG TABLET 15'S can also aid in weight management. Metformin has been shown to have a modest effect on weight loss or weight stabilization, which is beneficial for many individuals with type 2 diabetes who are often overweight or obese.
  • The combination of gliclazide and metformin in GLIMICURE M 4MG TABLET 15'S offers a synergistic effect, meaning that the two drugs work together to provide better blood sugar control than either drug could achieve alone. This can simplify your diabetes management regimen.
  • GLIMICURE M 4MG TABLET 15'S may also improve lipid profiles in some individuals. It can help lower triglycerides and LDL (bad) cholesterol levels, thereby reducing the risk of heart disease.
  • This medication is typically taken once or twice daily with meals, making it convenient to incorporate into your daily routine. Consistent timing with meals ensures optimal absorption and blood sugar control.
  • Consult your doctor for personalized advice on diet and exercise. Remember that GLIMICURE M 4MG TABLET 15'S works best when combined with a healthy lifestyle, including regular physical activity and a balanced diet. Regular monitoring by a healthcare provider is essential while taking this medication to ensure its effectiveness and to monitor for any potential side effects.
  • Taking GLIMICURE M 4MG TABLET 15'S consistently as prescribed will significantly help in overall diabetes management, improving your quality of life and reducing the risk of serious health complications associated with poorly controlled blood sugar levels. Always follow your doctor's instructions and attend regular check-ups to ensure optimal health outcomes.

How to use GLIMICURE M 4MG TABLET 15'SArrow

  • GLIMICURE M 4MG TABLET 15'S is a medication prescribed to manage blood sugar levels in individuals with type 2 diabetes. It's crucial to follow your doctor's instructions precisely regarding dosage and timing. Typically, this medication is taken orally, usually once or twice daily, with meals to minimize the risk of stomach upset. Swallow the tablet whole with a full glass of water, and do not crush, chew, or break it, as this can affect how the medication is released and absorbed.
  • Consistency is key for optimal results. Try to take GLIMICURE M 4MG TABLET 15'S at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • While taking GLIMICURE M 4MG TABLET 15'S, it's important to monitor your blood sugar levels regularly as directed by your healthcare provider. This will help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan. Also, adhere to a healthy diet and exercise regularly. GLIMICURE M 4MG TABLET 15'S works best when combined with lifestyle modifications. Limit your intake of sugary foods and drinks, and engage in regular physical activity to improve your body's response to insulin.
  • Be aware of potential side effects, such as hypoglycemia (low blood sugar). Symptoms of hypoglycemia may include shakiness, sweating, dizziness, confusion, and rapid heartbeat. If you experience these symptoms, consume a quick source of sugar, such as glucose tablets, fruit juice, or a sugary snack. It's also important to inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with GLIMICURE M 4MG TABLET 15'S.

Quick Tips for GLIMICURE M 4MG TABLET 15'SArrow

  • Take GLIMICURE M 4MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking it without consulting your physician. Consistent adherence ensures optimal blood sugar control and minimizes the risk of complications associated with diabetes. Remember, regular monitoring of blood glucose levels is crucial while on this medication to assess its effectiveness and make necessary adjustments.
  • GLIMICURE M 4MG TABLET 15'S is typically taken with meals to help manage blood sugar spikes after eating. It's best to take it at the same time each day to maintain a consistent level of medication in your body. This helps in better glucose regulation and reduces the chances of experiencing hypoglycemia (low blood sugar). Make sure to coordinate with your doctor or dietician for specific dietary guidelines to complement the medication's effects.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting GLIMICURE M 4MG TABLET 15'S. Certain medications can interact with this drug, potentially altering its effectiveness or increasing the risk of side effects. Common culprits include certain antibiotics, antifungals, and medications affecting kidney function. Transparency with your healthcare provider ensures safe and effective treatment.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) while taking GLIMICURE M 4MG TABLET 15'S. These symptoms can include shakiness, sweating, dizziness, hunger, and confusion. Always carry a source of fast-acting glucose, such as glucose tablets or fruit juice, to quickly raise your blood sugar if hypoglycemia occurs. Understanding and managing hypoglycemia is a critical part of diabetes management.
  • Maintain a healthy lifestyle while taking GLIMICURE M 4MG TABLET 15'S. This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. Lifestyle modifications, combined with medication, can significantly improve blood sugar control and overall health. Consult with your doctor or a certified diabetes educator for personalized guidance on diet and exercise.

Food Interactions with GLIMICURE M 4MG TABLET 15'SArrow

  • Glimicure M 4mg Tablet 15'S should be taken with food to avoid stomach upset. Maintain a consistent meal schedule.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar).
  • Inform your doctor about your dietary habits, especially if you are on a special diet (e.g., low-carb, ketogenic).
  • Monitor your blood sugar levels regularly, especially after meals, to understand how Glimicure M 4mg Tablet 15'S interacts with your diet.
  • Be cautious about consuming large amounts of sugary foods or drinks, as they can affect your blood sugar control.

FAQs

What is GLIMICURE M 4MG TABLET 15'S and what is it used for?Arrow

GLIMICURE M 4MG TABLET 15'S is a medication used to control high blood sugar levels in people with type 2 diabetes mellitus. It is a combination of two medicines, Glimepiride and Metformin.

How does GLIMICURE M 4MG TABLET 15'S work?Arrow

GLIMICURE M 4MG TABLET 15'S works in two ways: Glimepiride increases the amount of insulin that the pancreas releases, and Metformin helps your body respond better to insulin.

What are the common side effects of GLIMICURE M 4MG TABLET 15'S?Arrow

The common side effects of GLIMICURE M 4MG TABLET 15'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

Should GLIMICURE M 4MG TABLET 15'S be taken with food?Arrow

GLIMICURE M 4MG TABLET 15'S is generally recommended to be taken with food, especially with breakfast, to minimize the chance of stomach upset.

Is GLIMICURE M 4MG TABLET 15'S safe for kidneys?Arrow

GLIMICURE M 4MG TABLET 15'S should be used with caution in patients with kidney disease. Dosage adjustment may be needed. Please consult your doctor.

How to store GLIMICURE M 4MG TABLET 15'S?Arrow

Store GLIMICURE M 4MG TABLET 15'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Is GLIMICURE M 4MG TABLET 15'S safe during pregnancy?Arrow

GLIMICURE M 4MG TABLET 15'S is not recommended during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.

Is GLIMICURE M 4MG TABLET 15'S safe during breastfeeding?Arrow

GLIMICURE M 4MG TABLET 15'S is not recommended during breastfeeding. Consult your doctor if you are breastfeeding.

Does GLIMICURE M 4MG TABLET 15'S interact with alcohol?Arrow

Alcohol can increase the risk of side effects of GLIMICURE M 4MG TABLET 15'S, such as low blood sugar. Use caution when consuming alcohol with this medication.

What are the symptoms of an overdose of GLIMICURE M 4MG TABLET 15'S?Arrow

Symptoms of an overdose of GLIMICURE M 4MG TABLET 15'S may include low blood sugar (sweating, shaking, confusion), nausea, vomiting, and abdominal pain.

Can GLIMICURE M 4MG TABLET 15'S interact with other medications?Arrow

GLIMICURE M 4MG TABLET 15'S can interact with many other medications. Make sure you tell your doctor about all the medications you are taking, including over-the-counter medicines and herbal supplements.

What are the alternatives to GLIMICURE M 4MG TABLET 15'S?Arrow

Alternatives to GLIMICURE M 4MG TABLET 15'S include other combination medications containing Glimepiride and Metformin, or taking each medication separately. Your doctor can determine the best option for you.

Does GLIMICURE M 4MG TABLET 15'S cause weight gain?Arrow

GLIMICURE M 4MG TABLET 15'S can cause weight gain in some patients. A healthy diet and regular exercise can help manage weight.

Can I drive while taking GLIMICURE M 4MG TABLET 15'S?Arrow

GLIMICURE M 4MG TABLET 15'S can cause low blood sugar, which may affect your ability to drive. Do not drive if you feel dizzy, confused, or shaky.

What happens if I miss a dose of GLIMICURE M 4MG TABLET 15'S?Arrow

If you miss a dose of GLIMICURE M 4MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Is GLIMICURE M 4MG TABLET 15'S safe for long-term use?Arrow

GLIMICURE M 4MG TABLET 15'S can be used long-term as directed by your doctor. It is important to monitor your blood sugar levels and kidney function regularly.

References

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DrugBank: Glimipiride. Provides detailed chemical, pharmacological, and clinical information on glimepiride, one of the active ingredients in Glimicure M.

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FDA Label: Amaryl (glimepiride) tablets. Contains prescribing information, including pharmacology, clinical studies, and safety data for glimepiride.

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National Center for Biotechnology Information (NCBI): Efficacy and Safety of Teneligliptin Plus Metformin as a First-Line Treatment Option in Patients with Newly Diagnosed Type 2 Diabetes Mellitus. A study that can also contain details on metformin

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DrugBank: Metformin. Provides detailed chemical, pharmacological, and clinical information on metformin, one of the active ingredients in Glimicure M.

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FDA Label: Glucophage (metformin hydrochloride) tablets. Contains prescribing information, including pharmacology, clinical studies, and safety data for metformin.

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European Medicines Agency (EMA): Metformin-containing medicinal products. Provides European regulatory information and scientific assessment reports related to metformin.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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