GLUCONORM Z XR 60 TABLET 15'S
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GLUCONORM Z XR 60 TABLET 15'S
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GLUCONORM Z XR 60 TABLET 15'S

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GLUCONORM Z XR 60 TABLET 15'S

By LUPIN LIMITED

MRP

233.5

₹198.48

15 % OFF

₹13.23 Only /

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10

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Product DetailsArrow

About GLUCONORM Z XR 60 TABLET 15'S

  • GLUCONORM Z XR 60 Tablet is a combination medicine used to treat type 2 diabetes mellitus in adults. It combines two active ingredients, providing a dual approach to managing blood sugar levels. This medication is designed to be taken once daily, offering a convenient way to maintain glycemic control.
  • The primary ingredient in GLUCONORM Z XR is Metformin, a well-established biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. By reducing hepatic glucose output, Metformin helps lower fasting blood sugar levels. Simultaneously, it enhances the utilization of glucose by muscles and other tissues, further contributing to blood sugar control.
  • The secondary ingredient is a Sulfonylurea, which stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose enter cells from the bloodstream, thereby lowering blood sugar levels. By promoting insulin secretion, this component of GLUCONORM Z XR helps manage post-meal blood sugar spikes.
  • This extended-release (XR) formulation ensures a gradual release of the medication over an extended period, typically 24 hours. This helps in maintaining steady blood sugar levels throughout the day and reduces the risk of sudden drops in blood sugar (hypoglycemia). The XR formulation also often leads to better gastrointestinal tolerance compared to immediate-release formulations.
  • GLUCONORM Z XR is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels. It is important to take this medication as directed by your healthcare provider. Regular monitoring of blood sugar levels is crucial to assess the effectiveness of the treatment and make any necessary adjustments to the dosage. Like all medications, GLUCONORM Z XR may cause side effects, and it's important to discuss any concerns or symptoms with your doctor.

Uses of GLUCONORM Z XR 60 TABLET 15'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering blood sugar levels
  • Improving insulin sensitivity
  • Improving ovulation in polycystic ovary syndrome (PCOS) (in some cases)
  • Reducing the risk of heart disease (according to some studies)
  • Prevention of diabetic complications
  • Controlling post-meal blood sugar levels

How GLUCONORM Z XR 60 TABLET 15'S Works

  • GLUCONORM Z XR 60 Tablet 15's is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Metformin, Glimepiride, and Voglibose. Each component works through different mechanisms to lower blood glucose levels, providing comprehensive glycemic control.
  • Metformin, a biguanide, is the cornerstone of treatment for type 2 diabetes. It primarily works by decreasing glucose production in the liver. It reduces hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Additionally, Metformin enhances insulin sensitivity in peripheral tissues such as muscle and fat. This means that cells become more responsive to insulin, allowing them to uptake glucose more efficiently from the bloodstream. Metformin also slows down the absorption of glucose from the intestines, further contributing to its blood glucose-lowering effect. Importantly, Metformin does not stimulate insulin secretion, which minimizes the risk of hypoglycemia (low blood sugar) when used alone.
  • Glimepiride, a sulfonylurea, functions by stimulating the release of insulin from the beta cells in the pancreas. It binds to specific receptors on these cells, triggering a cascade of events that lead to the secretion of insulin. Insulin then facilitates the uptake of glucose by cells, lowering blood glucose levels. Glimepiride is particularly effective at reducing postprandial (after-meal) glucose spikes. However, because it directly stimulates insulin release, there is a risk of hypoglycemia, especially if meals are skipped or if the dosage is not appropriately adjusted.
  • Voglibose, an alpha-glucosidase inhibitor, works in the small intestine to delay the absorption of carbohydrates. It inhibits the action of alpha-glucosidase enzymes, which are responsible for breaking down complex carbohydrates into simpler sugars like glucose. By slowing down carbohydrate digestion, Voglibose reduces the postprandial rise in blood glucose levels. This mechanism is particularly useful for managing blood sugar after meals. Voglibose's effect is localized to the gut, and it does not significantly affect insulin secretion or sensitivity.
  • In combination, these three medications provide a multi-faceted approach to managing blood glucose. Metformin reduces glucose production and improves insulin sensitivity, Glimepiride stimulates insulin release, and Voglibose delays carbohydrate absorption. This synergistic action helps to maintain stable blood glucose levels throughout the day, reducing both fasting and postprandial hyperglycemia. Regular monitoring of blood glucose levels and adherence to a healthy diet and exercise plan are essential for optimizing the effectiveness of GLUCONORM Z XR 60 Tablet 15's.

Side Effects of GLUCONORM Z XR 60 TABLET 15'SArrow

Common side effects of GLUCONORM Z XR 60 Tablet 15'S may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Less common side effects can include hypoglycemia (low blood sugar), dizziness, headache, constipation, and skin rashes. Rare but serious side effects may involve lactic acidosis (build-up of lactic acid in the blood), liver problems, and allergic reactions. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for GLUCONORM Z XR 60 TABLET 15'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of GLUCONORM Z XR 60 TABLET 15'SArrow

  • The recommended dosage of GLUCONORM Z XR 60 TABLET 15'S should be determined by your physician based on your individual needs and response to treatment. It's typically taken once daily, preferably with the evening meal, to maximize its effectiveness in controlling blood sugar levels throughout the night and morning.
  • The starting dose may vary depending on your current medications and blood sugar levels. Your doctor may start you on a lower dose and gradually increase it as needed to achieve optimal glycemic control. It is crucial to adhere to your doctor's instructions regarding dosage adjustments.
  • GLUCONORM Z XR 60 TABLET 15'S is an extended-release formulation, meaning it releases the medication slowly over time. Therefore, it's important to swallow the tablet whole and not to crush, chew, or break it, as this could affect the drug's absorption and effectiveness.
  • If you miss a dose of GLUCONORM Z XR 60 TABLET 15'S, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It's important to monitor your blood sugar levels regularly while taking GLUCONORM Z XR 60 TABLET 15'S, as directed by your physician. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Remember that GLUCONORM Z XR 60 TABLET 15'S is most effective when used in conjunction with a healthy diet and regular exercise. Following a balanced meal plan and engaging in physical activity can significantly improve your blood sugar control.
  • Take 'GLUCONORM Z XR 60 TABLET 15'S' only as per the prescription by your physician only

What if I miss my dose of GLUCONORM Z XR 60 TABLET 15'S?Arrow

  • If you miss a dose of GLUCONORM Z XR 60 TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLUCONORM Z XR 60 TABLET 15'S?Arrow

  • Keep GLUCONORM Z XR 60MG TAB 1X15 away from the reach of children and pets.
  • Store GLUCONORM Z XR 60MG TAB 1X15 at room temperature.

Benefits of GLUCONORM Z XR 60 TABLET 15'SArrow

  • GLUCONORM Z XR 60 TABLET 15'S is a combination medicine used to effectively manage type 2 diabetes mellitus. It brings together the power of two active ingredients to offer comprehensive glycemic control, helping patients lead healthier lives.
  • This medication works through multiple mechanisms to lower blood glucose levels. Metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity in the body's tissues, allowing cells to utilize glucose more efficiently. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. This dual action ensures better control over blood sugar levels, particularly after meals.
  • One of the primary benefits of GLUCONORM Z XR is its ability to provide sustained release of the medication. The 'XR' in its name stands for extended release, meaning the drug is released slowly into the bloodstream over a longer period. This helps to maintain stable blood sugar levels throughout the day and reduces the risk of sudden spikes and drops.
  • Improved glycemic control achieved with GLUCONORM Z XR can significantly reduce the risk of long-term complications associated with diabetes. These complications include cardiovascular diseases, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). By keeping blood sugar levels within the target range, patients can protect their vital organs and improve their overall quality of life.
  • GLUCONORM Z XR is also beneficial because it simplifies the treatment regimen. Instead of taking multiple medications at different times, patients can often manage their condition with a single tablet taken once or twice daily. This improves adherence to the prescribed treatment plan, leading to better outcomes.
  • Furthermore, GLUCONORM Z XR can lead to improvements in other metabolic parameters. Some patients may experience a reduction in triglycerides and modest weight loss, which are additional benefits for those managing type 2 diabetes. However, it’s crucial to maintain a healthy diet and exercise regularly while taking this medication to maximize its effectiveness.
  • The combination of metformin and glimepiride in GLUCONORM Z XR offers a synergistic effect, meaning they work together to achieve better blood sugar control than either medication could achieve alone. This makes it a valuable option for patients who need more intensive therapy to reach their glycemic goals.
  • GLUCONORM Z XR contributes to enhanced energy levels and reduced fatigue often associated with poorly controlled diabetes. By stabilizing blood sugar, patients may experience improved physical and mental well-being, allowing them to engage in daily activities with greater ease.
  • It is essential to note that while GLUCONORM Z XR offers numerous benefits, it should always be taken under the guidance of a healthcare professional. Regular monitoring of blood sugar levels and kidney function is necessary to ensure the medication is both safe and effective. Potential side effects should be discussed with a doctor, and any concerns should be promptly addressed.

How to use GLUCONORM Z XR 60 TABLET 15'SArrow

  • GLUCONORM Z XR 60 Tablet is designed for oral administration and should be taken exactly as prescribed by your doctor. The typical starting dose is usually one tablet daily, but your doctor may adjust this based on your blood glucose levels and overall response to the medication. It's crucial to adhere to the prescribed dosage and not to alter it without consulting your healthcare provider.
  • This medication is best taken with food to help reduce the risk of stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system and potentially lead to adverse effects. It is generally recommended to take this medicine at the same time each day to maintain consistent blood levels.
  • Consistency is key to effectively managing your blood sugar. Try to incorporate GLUCONORM Z XR 60 Tablet into your daily routine, such as taking it with breakfast or dinner. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking GLUCONORM Z XR 60 Tablet, it's essential to monitor your blood glucose levels regularly, as directed by your doctor or diabetes educator. This will help you and your healthcare team assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep track of your blood sugar readings and share them with your doctor during your appointments.
  • It is crucial to maintain a healthy lifestyle while on this medication, including following a balanced diet and engaging in regular physical activity. These habits can significantly enhance the effectiveness of GLUCONORM Z XR 60 Tablet in controlling your blood sugar levels. Also, inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with this medication.

Quick Tips for GLUCONORM Z XR 60 TABLET 15'SArrow

  • Take GLUCONORM Z XR 60 Tablet 15'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It's best to take it with food to minimize stomach upset and help your body absorb the medication effectively. Consistency is key for managing your blood sugar levels, so try to take it at the same time each day.
  • Monitor your blood sugar regularly as directed by your healthcare provider while taking GLUCONORM Z XR 60 Tablet 15'S. Keep a record of your blood sugar readings to share with your doctor during your appointments. This will help them assess how well the medication is working for you and make any necessary adjustments to your treatment plan. Regular monitoring ensures you stay within your target blood sugar range.
  • Follow a healthy diet and exercise plan while taking GLUCONORM Z XR 60 Tablet 15'S. Focus on eating balanced meals with plenty of fruits, vegetables, and whole grains. Limit your intake of sugary and processed foods. Engage in regular physical activity, such as brisk walking, cycling, or swimming, for at least 30 minutes most days of the week. A healthy lifestyle complements the medication's effects in controlling blood sugar.
  • Be aware of the potential side effects of GLUCONORM Z XR 60 Tablet 15'S and what to do if they occur. Common side effects may include nausea, diarrhea, or stomach upset. If you experience any severe or persistent side effects, such as severe abdominal pain, yellowing of the skin or eyes, or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention. Knowing what to expect can help you manage your health proactively.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting GLUCONORM Z XR 60 Tablet 15'S. Certain medications can interact with GLUCONORM Z XR 60 Tablet 15'S, affecting its effectiveness or increasing the risk of side effects. This includes over-the-counter drugs, vitamins, and herbal remedies. Providing a complete medication list ensures your doctor can make informed decisions about your treatment.

Food Interactions with GLUCONORM Z XR 60 TABLET 15'SArrow

  • GLUCONORM Z XR 60 TABLET 15'S should be taken preferably with or immediately after meals to minimize gastrointestinal side effects. Consistent timing with meals is important for optimal blood sugar control.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar) and lactic acidosis.
  • Inform your doctor about your dietary habits, especially if you are on a specific diabetic diet, to ensure proper management of your blood sugar levels.

FAQs

What is Gluconorm Z XR 60 Tablet 15'S?Arrow

Gluconorm Z XR 60 Tablet 15'S is a combination of two medicines used to control high blood sugar levels in people with type 2 diabetes mellitus.

What is Gluconorm Z XR 60 Tablet 15'S used for?Arrow

Gluconorm Z XR 60 Tablet 15'S is used to treat type 2 diabetes mellitus, especially when diet and exercise alone are not enough to control blood sugar levels adequately.

How does Gluconorm Z XR 60 Tablet 15'S work?Arrow

Gluconorm Z XR 60 Tablet 15'S works by combining two medications: Metformin, which reduces glucose production in the liver, and Glimepiride, which lowers blood sugar by increasing the release of insulin.

What are the common side effects of Gluconorm Z XR 60 Tablet 15'S?Arrow

Common side effects of Gluconorm Z XR 60 Tablet 15'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is Gluconorm Z XR 60 Tablet 15'S safe for people with kidney problems?Arrow

Gluconorm Z XR 60 Tablet 15'S should be used with caution in people with kidney problems, as it can worsen kidney function. Dosage adjustment may be needed.

Is Gluconorm Z XR 60 Tablet 15'S safe during pregnancy?Arrow

Gluconorm Z XR 60 Tablet 15'S is not recommended during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.

Is Gluconorm Z XR 60 Tablet 15'S safe during breastfeeding?Arrow

Gluconorm Z XR 60 Tablet 15'S is not recommended during breastfeeding. Consult your doctor if you need to take this medication while breastfeeding.

Can I drink alcohol with Gluconorm Z XR 60 Tablet 15'S?Arrow

Drinking alcohol with Gluconorm Z XR 60 Tablet 15'S is not recommended, as it can increase the risk of low blood sugar and increase the side effects of the medication.

How to store Gluconorm Z XR 60 Tablet 15'S?Arrow

Store Gluconorm Z XR 60 Tablet 15'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

What happens if I miss a dose of Gluconorm Z XR 60 Tablet 15'S?Arrow

If you miss a dose of Gluconorm Z XR 60 Tablet 15'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Does Gluconorm Z XR 60 Tablet 15'S cause weight gain?Arrow

Gluconorm Z XR 60 Tablet 15'S may cause weight gain in some patients. Monitor your weight and consult your doctor if you notice any significant changes.

Can Gluconorm Z XR 60 Tablet 15'S cause low blood sugar (hypoglycemia)?Arrow

Yes, Gluconorm Z XR 60 Tablet 15'S can cause low blood sugar (hypoglycemia), especially if taken with other diabetes medications or if you skip meals.

What foods should I avoid while taking Gluconorm Z XR 60 Tablet 15'S?Arrow

While taking Gluconorm Z XR 60 Tablet 15'S, avoid high sugar and high-fat foods. Consult your doctor or a dietician for advice on maintaining a healthy diet.

Can Gluconorm Z XR 60 Tablet 15'S interact with other medications?Arrow

Yes, Gluconorm Z XR 60 Tablet 15'S can interact with certain other medications, such as some antibiotics, antifungals, and heart medications. Inform your doctor about all your medications before starting this medicine.

What are the alternatives to Gluconorm Z XR 60 Tablet 15'S?Arrow

Alternatives to Gluconorm Z XR 60 Tablet 15'S include single entities of Metformin, Glimepiride, or other anti-diabetic medications. Consult your doctor to find the best option for you.

References

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DrugBank: Metformin. Describes metformin's mechanism of action, pharmacology, and uses. Gluconorm Z XR contains metformin.

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FDA label for Metformin Hydrochloride Extended-Release Tablets. Provides detailed information on metformin, including its clinical pharmacology, indications, and dosage.

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The effect of metformin on vitamin B12 levels in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Discusses the potential impact of metformin on vitamin B12 levels.

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European Medicines Agency (EMA) - Metformin-containing medicinal products: Questions and answers on the review of metformin medicines. Addresses issues related to metformin medications.

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UpToDate: Metformin drug information. Provides comprehensive drug information on metformin, including side effects, interactions, and monitoring.

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Marketer / Manufacturer Details

LUPIN LIMITED

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India

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