GLURA MP 1000 TABLET 10'S

How GLURA MP 1000 TABLET 10'S Works

• GLURA MP 1000 Tablet is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Metformin, Pioglitazone, and Glimepiride, each working through different mechanisms to achieve comprehensive glycemic control.
• Metformin, a cornerstone in diabetes treatment, primarily reduces glucose production in the liver. It achieves this by inhibiting hepatic gluconeogenesis, the process where the liver generates glucose from non-carbohydrate sources. Additionally, Metformin enhances insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines, further contributing to lower blood sugar levels. Metformin's action doesn't typically cause hypoglycemia (low blood sugar) when used alone, which is a significant advantage.
• Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It primarily works by improving insulin sensitivity in peripheral tissues, including fat and muscle. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor that plays a crucial role in glucose and lipid metabolism. By activating PPARγ, Pioglitazone enhances the uptake and utilization of glucose in these tissues, effectively lowering blood glucose levels. It also helps reduce insulin resistance, a common problem in type 2 diabetes.
• Glimepiride is a sulfonylurea, a class of drugs that stimulates the pancreas to release more insulin. It works by binding to specific receptors on pancreatic beta cells, leading to the closure of potassium channels and subsequent depolarization of the cell membrane. This depolarization triggers the opening of calcium channels, resulting in an influx of calcium ions. The increased intracellular calcium concentration stimulates the release of insulin from the beta cells. Glimepiride's action is dependent on the presence of functional beta cells in the pancreas.
• By combining these three medications, GLURA MP 1000 Tablet addresses multiple aspects of type 2 diabetes. Metformin reduces glucose production and improves insulin sensitivity, Pioglitazone further enhances insulin sensitivity, and Glimepiride stimulates insulin release. This multi-pronged approach often results in better blood sugar control compared to using any of these medications alone. Regular monitoring of blood sugar levels and adherence to a healthy lifestyle, including diet and exercise, are essential for maximizing the benefits of GLURA MP 1000 Tablet.

Possible side effects of GLURA MP 1000 Tablet may include:\n\n* **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness.\n* **Uncommon:** Skin rash, itching, urticaria (hives), weakness, fatigue, constipation, flatulence, abnormal liver function tests, vitamin B12 deficiency (with long-term use), lactic acidosis (rare but serious). Signs of lactic acidosis include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness, or lightheadedness, and a slow or irregular heartbeat.\n* **Rare:** Allergic reactions (swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing), liver problems (hepatitis), blood disorders (anemia, leukopenia, thrombocytopenia).

• If you miss a dose of GLURA MP 1000 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep GLURA MP 1000MG TAB 1X10 away from the reach of children and pets.
• Store GLURA MP 1000MG TAB 1X10 at room temperature.

• Take GLURA MP 1000 Tablet 10'S as prescribed by your doctor, usually once or twice daily with meals. Consistency in timing helps maintain stable blood sugar levels.
• GLURA MP 1000 Tablet 10'S combines metformin and another antidiabetic medicine. It is crucial to adhere to your diet and exercise plan while taking this medication to maximize its effectiveness in managing type 2 diabetes.
• Inform your doctor about all other medications, including herbal supplements, you're currently taking before starting GLURA MP 1000 Tablet 10'S to avoid potential drug interactions. Some medicines can affect blood sugar levels.
• Monitor your blood sugar levels regularly as directed by your doctor while on GLURA MP 1000 Tablet 10'S. Keep a record of your readings to share with your healthcare provider during appointments, it will help doctor determine effectiveness of medicine.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, to treat it promptly. Consult your doctor to adjust dosage if hypoglycemia occurs frequently.
• Stay hydrated by drinking plenty of water throughout the day while taking GLURA MP 1000 Tablet 10'S, especially if you experience gastrointestinal side effects such as nausea or diarrhea. Dehydration can affect blood sugar levels.
• If you are scheduled for any surgery or medical procedure involving contrast dye, inform your doctor that you are taking GLURA MP 1000 Tablet 10'S. You may need to temporarily discontinue the medication to prevent kidney problems.
• While on GLURA MP 1000 Tablet 10'S, pay attention to your feet and practice good foot care. Inspect your feet daily for any cuts, blisters, or infections, and seek immediate medical attention if you notice anything unusual, as diabetes can impair healing.

• It is advisable to take GLURA MP 1000 TABLET 10'S with food to minimize the risk of gastrointestinal side effects like nausea, vomiting, and diarrhea.
• Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of lactic acidosis.