GRAFTSOL SOLUTION 500 ML
GRAFTSOL SOLUTION 500 ML
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GRAFTSOL SOLUTION 500 ML

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GRAFTSOL SOLUTION 500 ML

By GENNOVA BIOPHARMACEUTICALS LTD

MRP

7693

₹6923.7

10 % OFF

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Product DetailsArrow

About GRAFTSOL SOLUTION 500 ML

  • GRAFTSOL SOLUTION 500 ML is a specialized organ preservation solution designed to maintain the viability and functionality of organs outside the body during transplantation procedures. Organ transplantation offers a lifeline for individuals with end-stage organ failure, and the success of this complex procedure hinges on several critical factors, including effective organ preservation. This solution plays a vital role in bridging the gap between organ retrieval from the donor and transplantation into the recipient.
  • The primary purpose of GRAFTSOL SOLUTION 500 ML is to ensure that organs remain in optimal condition during the crucial period between removal from the donor and implantation into the recipient. This interval can be significant, and without proper preservation, organs can suffer damage that compromises their functionality. By using GRAFTSOL SOLUTION 500 ML, medical professionals can minimize this damage and maintain the organ's viability, increasing the likelihood of a successful transplant.
  • The selection of an appropriate organ preservation solution is paramount and depends on the specific organ being preserved, as well as the unique requirements of the transplantation process. GRAFTSOL SOLUTION 500 ML is formulated to meet these stringent requirements, providing a stable environment that slows metabolic processes and prevents cellular degradation. While generally safe, physicians will monitor for potential overdose symptoms, such as electrolyte imbalances or elevated amino acid and histidine levels.
  • In essence, GRAFTSOL SOLUTION 500 ML is an integral component of the organ transplantation process, contributing significantly to the preservation of organs and ultimately improving patient outcomes. Its use allows for a more controlled and effective transplantation procedure, offering hope and a chance at a healthier life for those in need of organ replacement.

Uses of GRAFTSOL SOLUTION 500 ML

  • GRAFTSOL SOLUTION 500 ML is employed to maintain the viability of donor organs, including the heart, kidneys, pancreas, and liver, in conjunction with their associated veins and arteries, prior to the transplantation procedure. It helps to ensure the organs remain in optimal condition for successful transplantation.

Side Effects of GRAFTSOL SOLUTION 500 MLArrow

Like all medications, GRAFTSOL SOLUTION 500 ML can cause side effects, although not everyone will experience them.

  • Allergic reactions
  • Metabolic imbalances
  • Thrombosis (formation of blood clots)
  • Infection
  • Swelling or edema
  • Changes in organ function
  • Bleeding or hemorrhage
  • Transient changes in electrolyte levels

Safety Advice for GRAFTSOL SOLUTION 500 MLArrow

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Pregnancy

CONSULT YOUR DOCTOR

Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.

Dosage of GRAFTSOL SOLUTION 500 MLArrow

  • Begin by meticulously preparing GRAFTSOL SOLUTION 500 ML following the precise guidelines provided by the manufacturer. This step is critical; ensure accurate dilution if the solution concentrate requires it. The concentration directly impacts the solution's efficacy in preserving the organ.
  • Pay close attention to the temperature of the GRAFTSOL SOLUTION 500 ML. The optimal temperature range is typically between 0°C and 8°C. Maintaining this temperature range is essential for slowing down metabolic processes and minimizing cellular damage during organ preservation. Use a calibrated thermometer to verify the temperature.
  • Select a container or bag appropriate for the size and shape of the organ to be preserved. The container should be sterile and designed to hold liquid without leaking. Gently place the organ inside the container.
  • Carefully pour the prepared GRAFTSOL SOLUTION 500 ML into the container until the organ is completely submerged. Ensure there are no air pockets around the organ, as these can lead to uneven preservation. The solution should fully envelop the organ to provide consistent cooling and preservation.
  • Securely close the container to prevent any leakage or contamination during transport. Use a tight-fitting lid or sealable bag. Double-check the seal to ensure it is airtight.
  • During transportation, rigorously maintain the recommended temperature range of 0°C to 8°C. Utilize appropriate cooling methods, such as ice packs or specialized refrigeration units designed for medical transport. Monitor the temperature regularly using a reliable thermometer to ensure it remains within the acceptable range. Consistent temperature control is vital for successful organ preservation and transplantation.

How to store GRAFTSOL SOLUTION 500 ML?Arrow

  • Keep GRAFTSOL SOLUTION 500ML away from the reach of children and pets.
  • Store GRAFTSOL SOLUTION 500ML at room temperature.

Benefits of GRAFTSOL SOLUTION 500 MLArrow

  • GRAFTSOL SOLUTION 500 ML plays a crucial role in preserving organs intended for transplantation. Its therapeutic benefit stems from its unique ability to sustain the health and functionality of these organs while they are outside the body.
  • By creating an environment that closely mimics the organ's natural conditions, GRAFTSOL SOLUTION 500 ML effectively extends the period during which the organ remains viable and suitable for transplantation. This extended shelf life significantly increases the chances of a successful transplant outcome.
  • The solution works by minimizing the damage that can occur during the preservation process, such as cellular degradation and tissue injury. It achieves this through a carefully balanced formulation that provides essential nutrients, buffers pH levels, and reduces oxidative stress.
  • Furthermore, GRAFTSOL SOLUTION 500 ML aids in reducing the risk of reperfusion injury, which can occur when the preserved organ is reintroduced to the recipient's blood supply. By mitigating these potential complications, it helps to ensure optimal organ function post-transplantation and improve patient outcomes.
  • Overall, GRAFTSOL SOLUTION 500 ML acts as a vital bridge between organ donation and transplantation, significantly improving the odds of successful transplantation and ultimately saving lives.

How to use GRAFTSOL SOLUTION 500 MLArrow

  • Prepare GRAFTSOL SOLUTION 500 ML according to the manufacturer's instructions. Pay close attention to the dilution requirements to ensure the solution is at the correct concentration for optimal organ preservation. If dilution is needed, use sterile techniques and appropriate sterile solutions to maintain the integrity of the GRAFTSOL SOLUTION 500 ML.
  • Once prepared, ensure the solution is at the recommended temperature, typically between 0°C and 8°C. Use a calibrated thermometer to verify the temperature. Maintaining this temperature range is critical for slowing down metabolic processes and minimizing cellular damage during preservation.
  • Next, carefully place the organ in a suitable sterile container or bag that is specifically designed for organ preservation. The container should be appropriately sized to hold the organ and the GRAFTSOL SOLUTION 500 ML without causing undue stress or compression.
  • Immerse the organ completely in the GRAFTSOL SOLUTION 500 ML, ensuring it is fully covered. Avoid air pockets or areas where the solution does not make direct contact with the organ's surface. Gentle agitation may be necessary to remove any trapped air.
  • Close the container securely to prevent leakage or contamination. Use a sealing method that is appropriate for the container type and ensures a tight, leak-proof closure. Label the container clearly with the organ type, date, and time of preservation.
  • During transportation, strictly maintain the recommended temperature range by using validated cooling methods, such as ice packs or refrigeration units. Monitor the temperature regularly using a data logger or thermometer to ensure it remains within the acceptable range throughout the transportation process. Document all temperature readings.
  • Handle the container with care during transport to prevent physical damage to the organ. Avoid sudden movements or impacts that could compromise the organ's integrity. Ensure the container is securely packed to prevent movement within the transport vehicle.

FAQs

Can GRAFTSOL SOLUTION 500 ML be used for preserving other biological tissues besides organs?Arrow

GRAFTSOL SOLUTION 500 ML is primarily designed and optimized for organ preservation. It is best to consult with healthcare professionals or researchers specialized in tissue preservation for specific recommendations.

Are there any alternative methods to GRAFTSOL SOLUTION 500 ML?Arrow

While GRAFTSOL SOLUTION 500 ML is the standard method for preserving organs, there is ongoing research into alternative preservation techniques. However, the use of such alternative methods may be limited to specific circumstances or still under investigation.

Can GRAFTSOL SOLUTION 500 ML reverse organ damage or restore organ function?Arrow

GRAFTSOL SOLUTION 500 ML is primarily used to maintain the viability and function of organs during the preservation period. They cannot reverse pre-existing organ damage or restore organ function independently.

Can GRAFTSOL SOLUTION 500 ML be reused or recycled?Arrow

GRAFTSOL SOLUTION 500 ML is typically single-use and designed for a specific preservation period. They are not intended to be reused or recycled due to the potential risk of contamination and reduced effectiveness.

Can GRAFTSOL SOLUTION 500 ML be stored for an extended period?Arrow

GRAFTSOL SOLUTION 500 ML have a limited shelf life and are usually stored under specific temperature conditions. It is important to check the expiration date and follow the manufacturer's guidelines for storage. Using expired solutions or improperly stored solutions may compromise their effectiveness and increase the risk of complications during transplantation.

What is the impact of GRAFTSOL SOLUTION 500 ML on the duration of organ preservation?Arrow

GRAFTSOL SOLUTION 500 ML is designed to extend the preservation time of organs outside the body, allowing for safe transportation and transplantation. The goal is to preserve the organ's viability for as long as necessary to ensure successful transplantation, but the duration can vary for different organs.

NULL interaction of GRAFTSOL SOLUTION 500 ML with other drungsArrow

There are no known interactions of GRAFTSOL SOLUTION 500 ML with other drugs.

What advice should I follow when using GRAFTSOL SOLUTION 500 ML?Arrow

If you are involved in organ transplantation procedures or considering the use of GRAFTSOL SOLUTION 500 ML, it is crucial to prioritize patient safety and follow proper guidelines and protocols. Always consult with experienced healthcare professionals, such as transplant specialists and medical experts, who can provide accurate and up-to-date information, guidance, and supervision throughout the process. A person should be cautious about overdose symptoms such as electrolyte imbalance, elevation of amino acids, and histidine levels in the plasma. Adhering to recommended practices, closely monitoring patients, and promptly addressing any concerns or complications will help ensure the best possible outcomes for donors and recipients.

What molecule/combination is used for making GRAFTSOL SOLUTION 500 ML?Arrow

ORGAN PRESERVATIVE SOLUTION is molecule/combination used for making GRAFTSOL SOLUTION 500 ML.

References

Book Icon

Methapharm Inc.

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Book Icon

Jing L et al, Organ preservation: from the past to the future, Acta Pharmacologica Sinica, 2018, 39: 845–857

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Reviewed on 24-05-2023

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Marketer / Manufacturer Details

GENNOVA BIOPHARMACEUTICALS LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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