HAEMACCEL INJECTION 500 ML

How HAEMACCEL INJECTION 500 ML Works

• HAEMACCEL INJECTION 500 ML is a plasma volume expander used to treat and prevent hypovolemia. Hypovolemia is a condition where there is a decreased volume of circulating blood in the body. It contains a combination of electrolytes and colloids, specifically polygeline. Polygeline is a modified gelatin molecule that acts as a plasma substitute. It works by increasing the osmotic pressure of the blood, which helps to draw fluid from the interstitial space (the space between cells) into the bloodstream, thereby increasing the circulating blood volume.
• The polygeline molecules in HAEMACCEL are large and remain in the bloodstream for a relatively long time, providing sustained volume expansion. This is crucial in situations where rapid restoration of blood volume is needed, such as in cases of severe bleeding, trauma, or surgery. The electrolytes present in the solution help to maintain the electrolyte balance in the body, which can be disrupted during hypovolemia.
• When HAEMACCEL is administered intravenously, the polygeline component exerts an oncotic effect, meaning it attracts water into the circulatory system. This immediate increase in blood volume helps to improve blood pressure and cardiac output, ensuring adequate oxygen delivery to vital organs. The expanded blood volume also aids in improving microcirculation, ensuring that oxygen and nutrients reach the tissues effectively. Over time, the polygeline molecules are broken down and eliminated from the body via the kidneys. It is a temporary solution to restore and maintain circulating blood volume while addressing the underlying cause of hypovolemia is essential.
• In essence, HAEMACCEL works by rapidly increasing the volume of fluid in your bloodstream. The polygeline within Haemaccel acts like a sponge, attracting water from other areas of the body into the circulation. This increased volume helps to improve blood pressure and ensures that vital organs receive the oxygen they need. Simultaneously, the balanced electrolyte solution within Haemaccel helps to correct any electrolyte imbalances that might accompany the fluid loss, contributing to overall stabilization of the patient's condition. The effect is temporary, providing crucial support while other treatments address the root cause of the hypovolemia.

Like all medicines, Haemaccel can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Skin reactions, such as hives (urticaria), itching (pruritus), and flushing (redness of the skin). * Mild to moderate decrease in blood pressure (hypotension). * Slowing of the heart rate (bradycardia). **Uncommon Side Effects (may affect up to 1 in 100 people):** * Nausea, vomiting * Shortness of breath (dyspnea). **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe allergic reactions (anaphylactic reactions) with symptoms such as: * Difficulty breathing, wheezing * Swelling of the face, lips, tongue, or throat * Rapid heart rate * Loss of consciousness * Increase in body temperature (fever) * Shivering (chills) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Cardiac arrest * Bronchospasm (narrowing of the airways) **Frequency not known (cannot be estimated from the available data):** * Disturbances of blood coagulation * Fluid overload (hypervolemia)

• As HAEMACCEL INJECTION 500 ML is administered by a healthcare professional, the chances of missing a dose are low. However, if you believe you may have missed a dose, inform your doctor or healthcare provider immediately. Do not attempt to self-administer if you think a dose was missed.

• Keep HAEMACCEL INJ 500ML away from the reach of children and pets.
• Store HAEMACCEL INJ 500ML at room temperature.

• **Maintain Adequate Hydration:** HAEMACCEL INJECTION 500 ML is often administered to restore blood volume. Ensure you maintain adequate hydration by drinking plenty of fluids as advised by your healthcare provider, especially after the infusion, to support optimal recovery and prevent dehydration-related complications. Staying well-hydrated helps your body adjust to the increased blood volume and promotes overall well-being.
• **Monitor for Allergic Reactions:** Although rare, allergic reactions can occur with HAEMACCEL INJECTION 500 ML. Watch closely for any signs of allergic reaction such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing. Report any such symptoms to your healthcare provider immediately. Prompt medical attention is crucial to manage allergic reactions effectively and prevent serious complications.
• **Follow Post-Infusion Instructions Carefully:** Your healthcare provider will provide specific instructions to follow after receiving HAEMACCEL INJECTION 500 ML. Adhere to these instructions meticulously, which may include monitoring your blood pressure, heart rate, and urine output. These parameters help assess your response to the treatment and identify any potential issues early on. Regular follow-up appointments are also important to ensure continued monitoring and optimal outcomes.
• **Understand Potential Side Effects:** Be aware of potential side effects associated with HAEMACCEL INJECTION 500 ML, such as fever, chills, nausea, or headache. While most side effects are mild and transient, it's important to be informed and recognize when medical attention may be necessary. Discuss any concerns or unexpected symptoms with your doctor or nurse promptly. They can provide guidance on managing side effects and ensuring your comfort.
• **Inform Your Healthcare Provider About Existing Conditions and Medications:** Before receiving HAEMACCEL INJECTION 500 ML, inform your healthcare provider about all existing medical conditions, especially heart, kidney, or lung problems, as well as any medications you are currently taking, including over-the-counter drugs and herbal supplements. This information is crucial for your healthcare provider to assess potential risks and interactions and ensure the safe and effective administration of HAEMACCEL INJECTION 500 ML. This will help in personalizing your treatment plan and maximizing its benefits.

• HAEMACCEL INJECTION 500 ML is generally administered by a healthcare professional and is unlikely to be affected by food intake. No specific food interactions have been identified. Patients can maintain their regular diet unless otherwise advised by their doctor.