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HEPCINAT LP TABLET 28'S

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HEPCINAT LP TABLET 28'S

By NATCO PHARMA LIMITED

MRP

25000

₹17067

31.73 % OFF

₹609.54 Only /

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About HEPCINAT LP TABLET 28'S

  • HEPCINAT LP is a prescription medication used to treat chronic Hepatitis C infection. It contains a combination of two powerful antiviral drugs: Sofosbuvir and Ledipasvir. This medication works by directly interfering with the Hepatitis C virus's ability to replicate, reducing the viral load in the body and helping to prevent further liver damage.
  • Sofosbuvir is a nucleotide analog inhibitor that blocks the action of the Hepatitis C virus RNA polymerase, an enzyme crucial for viral replication. Ledipasvir, on the other hand, is an NS5A inhibitor, which targets a protein also essential for the virus to multiply. By combining these two drugs, HEPCINAT LP provides a potent and comprehensive approach to fighting the Hepatitis C virus.
  • HEPCINAT LP is typically taken once daily, with or without food, as directed by your healthcare provider. It is crucial to adhere to the prescribed dosage and treatment duration to achieve the best possible outcome. The length of treatment can vary depending on individual factors, such as the genotype of the Hepatitis C virus and the presence of cirrhosis.
  • Before starting HEPCINAT LP, inform your doctor about any pre-existing medical conditions, allergies, and medications you are currently taking, including over-the-counter drugs and herbal supplements. This is essential to prevent potential drug interactions and ensure the safe and effective use of HEPCINAT LP. Common side effects may include fatigue, headache, nausea, and insomnia. Contact your healthcare provider if you experience any severe or persistent side effects.
  • HEPCINAT LP has demonstrated high cure rates for chronic Hepatitis C infection in clinical trials. It offers a well-tolerated and convenient treatment option for many patients. Regular monitoring and follow-up with your healthcare provider are important throughout the treatment course to assess your response and manage any potential side effects. Always store HEPCINAT LP in a cool, dry place, away from direct sunlight and out of reach of children.

Uses of HEPCINAT LP TABLET 28'S

  • Treatment of Hepatitis C Virus (HCV) infection
  • Treatment of chronic hepatitis C
  • Treatment of genotype 1, 4, 5 and 6 hepatitis C infections
  • Treatment of hepatitis C in patients with cirrhosis
  • Treatment of hepatitis C in patients with decompensated cirrhosis (in some cases)

How HEPCINAT LP TABLET 28'S Works

  • HEPCINAT LP TABLET 28'S is a combination medicine containing Ledipasvir and Sofosbuvir, both antiviral medications, primarily used to treat chronic Hepatitis C virus (HCV) infection. Hepatitis C is a viral infection that causes inflammation of the liver, and if left untreated, it can lead to serious liver damage, cirrhosis, liver cancer, or even liver failure. HEPCINAT LP works by directly interfering with the HCV replication process, thereby reducing the viral load in the body and helping to clear the infection over time.
  • Ledipasvir inhibits a protein called NS5A, which is essential for HCV replication and assembly. By blocking NS5A, Ledipasvir prevents the virus from multiplying and spreading to new cells within the liver. It disrupts the virus's ability to create new copies of itself, effectively halting the progression of the infection.
  • Sofosbuvir, on the other hand, is a nucleotide analog inhibitor that targets the HCV NS5B RNA-dependent RNA polymerase. This enzyme is crucial for the virus to replicate its RNA, which is its genetic material. Sofosbuvir gets incorporated into the viral RNA during replication, causing chain termination. This means that when the virus tries to copy its RNA, the presence of Sofosbuvir stops the process, preventing the formation of new viral particles. By inhibiting this key enzyme, Sofosbuvir effectively stops the virus from replicating.
  • The combination of Ledipasvir and Sofosbuvir in HEPCINAT LP offers a highly effective approach to treating Hepatitis C. Ledipasvir targets the NS5A protein, while Sofosbuvir targets the NS5B polymerase. By attacking the virus at two different points in its replication cycle, HEPCINAT LP significantly increases the chances of viral clearance. This dual mechanism of action makes HEPCINAT LP a potent and efficient treatment option for chronic HCV infection. The treatment regimen typically lasts for 12 weeks, and many patients achieve a sustained virologic response (SVR), which means the virus is no longer detectable in their blood after treatment, effectively curing the infection. It's crucial to take HEPCINAT LP exactly as prescribed by your doctor to ensure the best possible outcome.

Side Effects of HEPCINAT LP TABLET 28'SArrow

Common side effects of Hepcinat LP Tablet may include: * Fatigue * Headache * Nausea * Insomnia (trouble sleeping) * Diarrhea * Weakness * Irritability * Muscle aches (myalgia) Less common, but potentially serious side effects may include: * Depression or mood changes * Anxiety * Difficulty concentrating * Memory problems * Skin rash or itching * Shortness of breath * Chest pain It is important to contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for HEPCINAT LP TABLET 28'SArrow

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Allergies

Allergies

Inform your doctor if you are allergic to HEPCINAT LP TABLET 28'S or any of its ingredients.

Dosage of HEPCINAT LP TABLET 28'SArrow

  • The recommended dosage of HEPCINAT LP TABLET 28'S is one tablet taken orally once daily. It is crucial to adhere to this regimen consistently for the entire duration prescribed by your healthcare provider. Typically, the treatment course lasts for 12 weeks, but this can vary depending on the specific genotype of the hepatitis C virus (HCV) and the presence of cirrhosis. Do not alter the dosage or discontinue the medication prematurely, even if you start feeling better, without consulting your doctor. Premature discontinuation can lead to treatment failure and the development of drug resistance.
  • HEPCINAT LP TABLET 28'S can be taken with or without food, but it's generally recommended to take it at the same time each day to maintain a consistent level of the medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any concerns about missed doses, consult your physician or pharmacist.
  • Before starting HEPCINAT LP TABLET 28'S, inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications can interact with HEPCINAT LP TABLET 28'S, potentially affecting its efficacy or increasing the risk of side effects. Your doctor may need to adjust the dosages of your other medications or monitor you more closely for side effects. Regular blood tests will be required during treatment to monitor your liver function and the levels of HCV in your blood. These tests help your doctor assess how well the treatment is working and whether any adjustments are needed.
  • Take 'HEPCINAT LP TABLET 28'S' only as per the prescription by your physician only

What if I miss my dose of HEPCINAT LP TABLET 28'S?Arrow

  • If you miss a dose of Hepcinat LP, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store HEPCINAT LP TABLET 28'S?Arrow

  • Keep HEPCINAT LP TAB 1X28 away from the reach of children and pets.
  • Store HEPCINAT LP TAB 1X28 at room temperature.

Benefits of HEPCINAT LP TABLET 28'SArrow

  • HEPCINAT LP TABLET 28'S is a combination medicine used in the treatment of chronic hepatitis C virus (HCV) infection. It contains two active ingredients: Ledipasvir and Sofosbuvir. This medication works by inhibiting the replication of the HCV virus, effectively reducing the viral load in the body and slowing down the progression of liver damage.
  • Ledipasvir works by targeting the NS5A protein, which is essential for the replication of the hepatitis C virus. By inhibiting this protein, Ledipasvir prevents the virus from multiplying and infecting new liver cells.
  • Sofosbuvir inhibits the NS5B RNA-dependent RNA polymerase, another crucial enzyme for HCV replication. By blocking this enzyme, Sofosbuvir prevents the virus from making copies of itself, thereby reducing the viral load.
  • The combination of Ledipasvir and Sofosbuvir in HEPCINAT LP provides a synergistic effect, leading to a higher rate of sustained virologic response (SVR), which means the virus is undetectable in the blood after treatment. This significantly improves the chances of a complete cure.
  • HEPCINAT LP is a direct-acting antiviral (DAA) medication, meaning it directly targets the virus rather than boosting the immune system. This results in a more effective and targeted treatment with fewer side effects compared to older interferon-based therapies.
  • Clinical trials have demonstrated high cure rates (often exceeding 90%) with HEPCINAT LP, regardless of the HCV genotype (specific strain of the virus). This makes it a versatile treatment option for a wide range of patients.
  • Compared to older treatments for hepatitis C, HEPCINAT LP typically has a shorter treatment duration, often lasting only 12 weeks. This reduces the burden on patients and improves adherence to the treatment regimen.
  • HEPCINAT LP is generally well-tolerated, with most patients experiencing mild or no side effects. Common side effects may include fatigue, headache, nausea, and insomnia, but these are usually manageable and resolve quickly.
  • By effectively treating and curing hepatitis C, HEPCINAT LP can prevent the long-term complications associated with the infection, such as cirrhosis (scarring of the liver), liver failure, and liver cancer. Early treatment with HEPCINAT LP can significantly improve a patient's long-term health and quality of life.
  • HEPCINAT LP can also improve liver function in patients with hepatitis C. As the virus is eliminated, the liver can begin to heal and regenerate, leading to improved liver enzyme levels and overall liver health.
  • Treatment with HEPCINAT LP can reduce the risk of transmitting the hepatitis C virus to others. By achieving viral suppression, patients become non-infectious, helping to prevent the spread of the virus within the community.
  • HEPCINAT LP offers a convenient once-daily oral administration, making it easy for patients to incorporate into their daily routine. This improves adherence and ensures consistent medication levels in the body for optimal antiviral activity.
  • HEPCINAT LP can reduce the need for liver transplantation in patients with advanced liver disease caused by hepatitis C. By halting the progression of liver damage, the medication can prevent the need for this major surgical procedure.
  • HEPCINAT LP is suitable for many patients, including those with compensated cirrhosis (early-stage liver damage). However, it is essential to consult with a healthcare professional to determine if HEPCINAT LP is the right treatment option for your specific situation.
  • HEPCINAT LP can lead to significant cost savings in the long run by preventing the need for expensive treatments associated with advanced liver disease, such as liver transplantation and management of complications.
  • HEPCINAT LP improves the overall quality of life for individuals infected with chronic hepatitis C. By eradicating the virus, it can reduce fatigue, improve energy levels, and enhance overall well-being, allowing individuals to lead more active and fulfilling lives.
  • HEPCINAT LP helps to prevent the development of hepatocellular carcinoma (HCC), a type of liver cancer, in individuals with chronic hepatitis C infection. By eliminating the virus, it significantly reduces the risk of developing this serious complication.
  • HEPCINAT LP reduces inflammation in the liver, preventing further damage to liver cells and tissues. This can help to slow down the progression of liver disease and improve liver function.
  • HEPCINAT LP contributes to the global effort to eliminate hepatitis C as a public health threat. By providing an effective and accessible treatment option, it helps to reduce the burden of this infectious disease worldwide.
  • HEPCINAT LP is designed to be used as part of a comprehensive treatment plan, which may include lifestyle modifications, regular monitoring, and other supportive therapies. A holistic approach to care can further improve treatment outcomes and overall health.

How to use HEPCINAT LP TABLET 28'SArrow

  • HEPCINAT LP TABLET 28'S is a prescription medication used to treat chronic hepatitis C infection. It is crucial to take this medication exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, even if you feel better. Typically, HEPCINAT LP is taken orally once daily, with or without food. Try to take it at the same time each day to maintain a consistent level of the medication in your body.
  • Before starting HEPCINAT LP, inform your doctor about any other medical conditions you have, especially liver problems other than hepatitis C, kidney problems, or HIV infection. Also, disclose all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, as drug interactions can occur. Certain medications may need to be adjusted or avoided while you are taking HEPCINAT LP.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. During treatment with HEPCINAT LP, it's important to follow up with your doctor regularly for blood tests to monitor your liver function and the effectiveness of the treatment. Your doctor will advise you on the duration of treatment, which can vary depending on the severity of your condition and your response to the medication. Adhering to the full course of treatment is essential for achieving the best possible outcome.
  • Store HEPCINAT LP TABLET 28'S at room temperature, away from heat, light, and moisture. Keep the medication out of reach of children and pets. If you experience any unusual or severe side effects, such as fatigue, nausea, headache, or skin rash, contact your doctor immediately.

Quick Tips for HEPCINAT LP TABLET 28'SArrow

  • Take HEPCINAT LP TABLET 28'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could affect the treatment's effectiveness in managing your hepatitis C infection.
  • HEPCINAT LP is most effective when taken at the same time each day. This helps maintain a consistent level of the medication in your body, which is crucial for optimal viral suppression. Set a daily reminder if needed to help you adhere to the schedule.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. Certain substances can interact with HEPCINAT LP, potentially altering its effectiveness or increasing the risk of side effects. This includes over-the-counter drugs.
  • While taking HEPCINAT LP, regular blood tests are necessary to monitor your liver function and the levels of the hepatitis C virus in your blood. These tests help your doctor assess how well the treatment is working and adjust it if needed.
  • Be aware of potential side effects, such as fatigue, headache, nausea, or insomnia. If you experience any severe or persistent side effects, contact your doctor immediately. They can provide guidance on managing these effects and ensuring your comfort during treatment.
  • Store HEPCINAT LP at room temperature, away from moisture and heat. Keep the medication in its original container and out of reach of children. Proper storage ensures the medication remains effective throughout the treatment period.
  • Avoid alcohol consumption while taking HEPCINAT LP. Alcohol can further damage your liver and interfere with the medication's ability to effectively treat hepatitis C. Consult your doctor about safe lifestyle choices during treatment.

Food Interactions with HEPCINAT LP TABLET 28'SArrow

  • HEPCINAT LP TABLET 28'S can be taken with or without food. However, it is important to take the medicine at the same time each day to maintain consistent blood levels. Avoid taking HEPCINAT LP TABLET 28'S with antacids containing aluminum or magnesium, as they can decrease the absorption of the medication. If you need to take antacids, take them at least 4 hours before or 4 hours after taking HEPCINAT LP TABLET 28'S. There are no specific food restrictions while taking this medication, but it is always recommended to maintain a healthy diet.

FAQs

What is Hepcinat LP Tablet?Arrow

Hepcinat LP Tablet is an antiviral medicine used to treat chronic Hepatitis C infection. It contains two medicines: Ledipasvir and Sofosbuvir.

What is Hepcinat LP Tablet used for?Arrow

Hepcinat LP Tablet is used to treat Hepatitis C virus (HCV) infection.

How does Hepcinat LP Tablet work?Arrow

Hepcinat LP Tablet works by preventing the Hepatitis C virus from multiplying, helping to clear the virus from the body.

What is the common dosage of Hepcinat LP Tablet?Arrow

The usual dosage is one tablet daily, as directed by your doctor.

What are the side effects of Hepcinat LP Tablet?Arrow

Common side effects may include fatigue, headache, nausea, and difficulty sleeping.

Can Hepcinat LP Tablet be taken with or without food?Arrow

Hepcinat LP Tablet can be taken with or without food, but it is best to take it at the same time each day.

How should Hepcinat LP Tablet be stored?Arrow

Hepcinat LP Tablet should be stored at room temperature, away from moisture and heat.

Does Hepcinat LP Tablet interact with other medications?Arrow

Hepcinat LP Tablet can interact with certain medications, so it is important to tell your doctor about all the medications you are taking.

How long does treatment with Hepcinat LP Tablet last?Arrow

The duration of treatment is typically 12 weeks, but it will be determined by your doctor.

What happens if I miss a dose of Hepcinat LP Tablet?Arrow

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Is it safe to drink alcohol while taking Hepcinat LP Tablet?Arrow

It is best to avoid drinking alcohol while taking Hepcinat LP Tablet, as it can increase the risk of liver problems.

Can pregnant women take Hepcinat LP Tablet?Arrow

Hepcinat LP Tablet is not recommended during pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant.

Can breastfeeding women take Hepcinat LP Tablet?Arrow

It is not known whether Hepcinat LP Tablet passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

Does Hepcinat LP Tablet cause hair loss?Arrow

Hair loss is not a common side effect of Hepcinat LP Tablet. If you experience hair loss, talk to your doctor.

Is Velpatasvir and Sofosbuvir the same as Hepcinat LP Tablet?Arrow

Hepcinat LP Tablet contains Ledipasvir and Sofosbuvir, while Velpatasvir and Sofosbuvir is another combination medication used to treat Hepatitis C. Your doctor will determine the most appropriate option for you.

References

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European Medicines Agency (EMA) - Harvoni (ledipasvir / sofosbuvir) EPAR. While not directly Hepcinat LP, Harvoni contains Ledipasvir and Sofosbuvir, the same active ingredients, and the EPAR provides extensive technical information.

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FDA - HARVONI (ledipasvir and sofosbuvir) tablets label. Official US FDA label for Harvoni, containing detailed pharmacological and clinical trial information for ledipasvir and sofosbuvir.

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Sofosbuvir and Ledipasvir: A New Chapter in the Treatment of Chronic Hepatitis C. A review article from the National Center for Biotechnology Information (NCBI) discussing the efficacy and safety of sofosbuvir and ledipasvir combination therapy.

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EASL Recommendations on Treatment of Hepatitis C 2018. Clinical practice guidelines from the European Association for the Study of the Liver (EASL) regarding the treatment of Hepatitis C, including regimens containing sofosbuvir and ledipasvir.

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WHO Expert Committee on Specifications for Pharmaceutical Preparations. Fifty-first Report. This report from the World Health Organization (WHO) may contain information about quality control and specifications for pharmaceutical preparations including antivirals. Sofosbuvir is listed in the WHO Model List of Essential Medicines.

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DrugBank - Sofosbuvir. A comprehensive drug information resource containing chemical structures, mechanisms of action, and pharmacokinetic data for Sofosbuvir.

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DrugBank - Ledipasvir. A comprehensive drug information resource containing chemical structures, mechanisms of action, and pharmacokinetic data for Ledipasvir.

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NCBI PubMed. Search for specific research articles on Ledipasvir and Sofosbuvir. Example search terms: 'Ledipasvir pharmacokinetics', 'Sofosbuvir clinical trials'.

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Marketer / Manufacturer Details

NATCO PHARMA LIMITED

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India

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HEPCINAT LP TABLET 28'S

MRP

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₹17067

31.73 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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