HUMAPEN ERGO

How HUMAPEN ERGO Works

• HUMAPEN ERGO is a sophisticated insulin pen designed for convenient and precise insulin delivery. Its mechanism of action is intricately linked to the type of insulin it contains, typically a rapid-acting or long-acting insulin analog. Let's break down how it works:
• The insulin within HUMAPEN ERGO mimics the action of naturally produced insulin in the body. Insulin's primary role is to regulate blood glucose levels by enabling glucose uptake from the bloodstream into cells, where it can be used for energy. In individuals with diabetes, either the pancreas doesn't produce enough insulin (Type 1 diabetes) or the body becomes resistant to insulin's effects (Type 2 diabetes). HUMAPEN ERGO provides a means to supplement or replace the body's own insulin.
• When you inject insulin using HUMAPEN ERGO, the insulin is absorbed into the bloodstream. Rapid-acting insulin analogs begin to work within 15 minutes, peaking in about an hour, and lasting for 2-4 hours. These are typically used before meals to cover the rise in blood glucose from the food you eat. Long-acting insulin analogs, on the other hand, are designed to release insulin slowly and steadily over a period of 24 hours or more. They provide a basal level of insulin to keep blood glucose levels stable between meals and overnight.
• HUMAPEN ERGO allows for precise dosing, enabling you to administer the exact amount of insulin prescribed by your doctor. The pen features a dial that allows you to select the desired dose in units of insulin. Once the dose is selected, you insert the needle into a subcutaneous (under the skin) injection site, typically in the abdomen, thigh, or upper arm, and press the injection button. The insulin is then delivered into the subcutaneous tissue, from where it is absorbed into the bloodstream.
• The effectiveness of HUMAPEN ERGO depends on several factors, including the type of insulin used, the dosage, the timing of injections, your diet, and your activity level. It's crucial to work closely with your healthcare provider to determine the appropriate insulin regimen and to monitor your blood glucose levels regularly to ensure that you are achieving optimal glycemic control. Proper injection technique and site rotation are also important to prevent skin problems and ensure consistent insulin absorption.

Like all medicines, HUMAPEN ERGO can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): Symptoms may include shakiness, sweating, anxiety, blurred vision, tingling lips, paleness, headache, change in heart rate and confusion. Severe hypoglycemia can lead to unconsciousness and, in very rare circumstances, be fatal. * Injection site reactions: Redness, swelling, itching, or pain at the injection site. * Lipodystrophy: Changes in fat tissue at the injection site (lipoatrophy - thinning of fat or lipohypertrophy - thickening of fat) can occur if injections are repeatedly given in the same area. Keep rotating injection sites to avoid these skin changes. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Allergic reactions: Skin rash, itching, hives. * Edema: Swelling of ankles and feet due to fluid retention. **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe allergic reaction (anaphylaxis): Symptoms may include generalized skin reactions, difficulty breathing, wheezing, drop in blood pressure, fast pulse, or sweating. Seek immediate medical attention. **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Visual disturbances: Temporary visual impairment may occur at the beginning of insulin therapy. * Myalgia: Muscle pain. **Other possible side effects:** * Weight gain * Peripheral neuropathy (nerve damage causing pain, numbness, and tingling) **Important Considerations:** * This is not a complete list of side effects. Tell your doctor or pharmacist if you notice any other side effects. * Reported side effects may also depend on other factors like other underlying medical conditions or medicines the patient is already taking. * Always consult with your healthcare provider for personalized advice about managing side effects.

• If you miss a dose of Humapen Ergo, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• It is important to maintain consistent blood sugar levels. Try to take Humapen Ergo at the same times each day to avoid missed doses.
• If you frequently miss doses, discuss strategies with your doctor or pharmacist to help you remember.

• Keep HUMAPEN ERGO away from the reach of children and pets.
• Store HUMAPEN ERGO at room temperature.

• Always wash your hands thoroughly before using HumaPen Ergo. This helps prevent infection at the injection site and ensures a clean administration process.
• Inspect the insulin cartridge in your HumaPen Ergo before each use. Look for any discoloration, cloudiness, or particles. If you notice any of these, do not use the pen and use a new cartridge. Insulin should be clear and colorless (except for NPH insulin, which is cloudy).
• Prime your HumaPen Ergo before each injection, even if it's a new pen or cartridge. Priming removes air bubbles from the needle and ensures you get the correct dose of insulin. Dial up 2 units and inject into the air until insulin comes out.
• Rotate your injection sites regularly to prevent lipohypertrophy (lumps under the skin). Choose a different area each time you inject, such as your abdomen, thigh, or upper arm, and keep a record of where you last injected.
• Use a new needle for each injection with your HumaPen Ergo. Reusing needles can dull the needle tip, making injections more painful, and increases the risk of infection. Dispose of used needles safely in a sharps container.
• When dialing your dose on HumaPen Ergo, double-check the number in the dose window to ensure you've selected the correct amount of insulin. Accurate dosing is crucial for managing your blood sugar levels effectively.
• After injecting your insulin with HumaPen Ergo, hold the needle in place for at least 10 seconds before removing it. This ensures that the full dose of insulin is delivered and prevents leakage.
• Store your HumaPen Ergo and insulin cartridges properly. Unopened cartridges should be stored in the refrigerator, while the pen in use can be kept at room temperature for up to 28 days, away from direct sunlight and heat.
• If you travel with your HumaPen Ergo, keep it with you in your carry-on luggage. Extreme temperatures in checked baggage can damage the insulin. Also, carry a copy of your prescription in case you need to replace your insulin.
• Regularly monitor your blood sugar levels as directed by your healthcare provider. This helps you understand how your insulin dose is affecting your blood sugar and allows you to make adjustments as needed in consultation with your doctor.

• There are no known direct interactions between HUMAPEN ERGO and food. You can take HUMAPEN ERGO regardless of your meals. However, maintaining a consistent dietary pattern is important for overall diabetes management. Consult your healthcare provider for personalized advice regarding diet and HUMAPEN ERGO.