IBUGESIC PLUS SUSPENSION 60 ML

How IBUGESIC PLUS SUSPENSION 60 ML Works

• IBUGESIC PLUS SUSPENSION 60 ML is a widely used medication formulated to alleviate pain and reduce fever, especially in children. Its effectiveness stems from the synergistic action of its two active ingredients: Ibuprofen and Paracetamol (Acetaminophen). Understanding how each component works is crucial to appreciating the overall mechanism of this suspension.
• Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), primarily functions by inhibiting the production of prostaglandins. Prostaglandins are hormone-like substances that contribute to inflammation, pain, and fever. They are synthesized by an enzyme called cyclooxygenase (COX). Ibuprofen works by blocking both COX-1 and COX-2 enzymes. By inhibiting these enzymes, Ibuprofen reduces the synthesis of prostaglandins, thereby diminishing inflammation, pain, and fever. The reduction in prostaglandin levels helps to alleviate discomfort associated with conditions like headaches, toothaches, muscle aches, and arthritis.
• Paracetamol (Acetaminophen), on the other hand, has a different mechanism of action. While the exact mechanism is not fully understood, it is believed to primarily act within the central nervous system (CNS). Paracetamol is thought to inhibit prostaglandin synthesis in the brain, which contributes to its antipyretic (fever-reducing) and analgesic (pain-relieving) effects. Unlike NSAIDs, Paracetamol has minimal anti-inflammatory effects because it weakly inhibits COX enzymes in the peripheral tissues. This explains why it's often preferred for pain and fever relief without the anti-inflammatory benefits of drugs like Ibuprofen.
• The combination of Ibuprofen and Paracetamol in IBUGESIC PLUS SUSPENSION provides a multi-pronged approach to managing pain and fever. Ibuprofen tackles inflammation and pain peripherally by reducing prostaglandin production at the site of injury or inflammation. Meanwhile, Paracetamol acts centrally to reduce fever and pain perception in the brain. This dual action often results in more effective relief than using either medication alone, particularly in cases where both inflammation and pain are prominent.
• In summary, IBUGESIC PLUS SUSPENSION 60 ML works by leveraging the distinct yet complementary actions of Ibuprofen and Paracetamol. Ibuprofen inhibits prostaglandin synthesis via COX enzyme blockade, reducing inflammation and pain. Paracetamol primarily acts within the central nervous system to alleviate fever and pain. Together, they provide comprehensive relief from a range of conditions characterized by pain, fever, and inflammation, making it a valuable option for managing discomfort, especially in pediatric care.

IBUGESIC PLUS SUSPENSION 60 ML, like other medications, can cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, and indigestion. Some individuals might experience dizziness, drowsiness, headache, or blurred vision. Less common but potentially serious side effects could involve allergic reactions (rash, itching, swelling), difficulty breathing, high blood pressure, liver problems (yellowing of skin/eyes), kidney problems (changes in urine output), or signs of bleeding (bloody/black stools, unusual bruising). In rare cases, IBUGESIC PLUS SUSPENSION 60 ML can lead to more severe issues such as stomach ulcers, gastrointestinal bleeding, or heart problems. If you experience any persistent or worsening side effects, or if you notice signs of a serious allergic reaction or other concerning symptoms, discontinue use and seek immediate medical attention. This is not an exhaustive list, and it's crucial to consult the product leaflet or a healthcare professional for a complete understanding of potential side effects and their management. Long-term use may increase the risk of certain side effects.

• If you miss a dose of IBUGESIC PLUS SUSPENSION, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

• Keep IBUGESIC PLUS SUSPENSION 60ML away from the reach of children and pets.
• Store IBUGESIC PLUS SUSPENSION 60ML at room temperature.

• Shake Well Before Use: Always shake the IBUGESIC PLUS suspension bottle well before each use to ensure the medicine is properly mixed and that each dose contains the correct amount of medication. This ensures consistent and effective relief from fever and pain.
• Administer with a Measuring Device: Use the provided measuring cup or dropper to administer the correct dose. Household spoons can vary in size and may lead to inaccurate dosing, which can be harmful, especially for children. Accurate dosing ensures the medication works as intended.
• Give with Food if Needed: If your child experiences stomach upset after taking IBUGESIC PLUS, administer the dose with or shortly after a meal. This can help reduce the risk of nausea, vomiting, or stomach pain. However, consult your doctor if stomach upset persists.
• Monitor for Allergic Reactions: Watch for signs of an allergic reaction, such as rash, itching, swelling (especially of the face, tongue, or throat), or difficulty breathing. If any of these symptoms occur, seek immediate medical attention. Early detection and treatment of allergic reactions are crucial.
• Do Not Exceed Recommended Dosage: Never exceed the recommended dose or frequency of IBUGESIC PLUS. Overdosing can lead to serious side effects, including liver damage. If the fever or pain persists despite following the recommended dosage, consult your doctor instead of increasing the dose.
• Store Properly: Store IBUGESIC PLUS suspension in a cool, dry place, away from direct sunlight and heat. Keep the bottle tightly closed and out of reach of children. Proper storage helps maintain the medication's effectiveness and prevents accidental ingestion.

• IBUGESIC PLUS SUSPENSION 60 ML can be taken with or without food. However, giving it with food may help to prevent stomach upset. Follow your doctor's instructions regarding the timing of administration.