IMFINZI 120MG/2.4ML INJECTION
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IMFINZI 120MG/2.4ML INJECTION
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IMFINZI 120MG/2.4ML INJECTION

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IMFINZI 120MG/2.4ML INJECTION

By ASTRAZENECA PHARMA INDIA LIMITED

MRP

45500

₹34760

23.6 % OFF

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Product DetailsArrow

About IMFINZI 120MG/2.4ML INJECTION

  • IMFINZI 120MG/2.4ML INJECTION contains Durvalumab, an active ingredient that belongs to the Anti-PD-1 monoclonal antibodies class of anticancer drugs. It is prescribed for the treatment of non-small cell lung cancer (when it hasn't spread beyond the chest), small cell lung cancer (when it has spread within the lungs), and biliary tract cancers (cancers affecting the bile ducts). Prior to starting this injection, inform your healthcare provider if you have a history of organ transplant, liver conditions, lung or breathing difficulties, or autoimmune disorders (where the immune system mistakenly attacks the body's own cells).
  • Common side effects associated with this injection may include cough, upper respiratory tract infections, fatigue, shortness of breath, lung inflammation, and skin rash. This medication may elevate the risk of immune-mediated adverse reactions such as pneumonitis, colitis, hepatitis, endocrinopathies, and nephritis. Regular monitoring and communication with your doctor are essential to manage potential side effects effectively.
  • This medication is not suitable for adolescents and children under 18 years of age. During treatment with IMFINZI 120MG/2.4ML INJECTION, your doctor will conduct routine monitoring of white blood cell counts, platelets, blood sugar levels, electrolytes, and kidney function to proactively identify and manage any potential complications. It is frequently administered alongside carboplatin or cisplatin for treating small-cell lung cancer, and in conjunction with gemcitabine for biliary tract cancer. This medicine carries a risk of kidney-related issues, so it's crucial to inform your doctor about any pre-existing kidney disorders, heart failure, elevated blood cholesterol, or hypertension before initiating treatment.

Uses of IMFINZI 120MG/2.4ML INJECTION

  • Non-Small Cell Lung Cancer: This refers to a group of lung cancers that behave similarly and are treated similarly. It is the most common type of lung cancer. Therapies like IMFINZI 120MG/2.4ML INJECTION are often part of the treatment plan.
  • Small Cell Lung Cancer: This is a fast-growing type of lung cancer that often requires aggressive treatment. While IMFINZI 120MG/2.4ML INJECTION might not be a primary treatment, it could be used in certain combinations or circumstances.
  • Biliary Tract Cancer: This cancer affects the bile ducts, which connect the liver and gallbladder to the small intestine. Treatment options can include surgery, chemotherapy, and radiation, and in some cases, immunotherapy involving drugs like IMFINZI 120MG/2.4ML INJECTION.

Side Effects of IMFINZI 120MG/2.4ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Serious side effects may include infection (chills, increased temperature), serious lung infections (pneumonia), fungal infection in the mouth, tooth and mouth soft tissue infections, flu-like illness, overactive thyroid gland that can cause fast heart rate or weight loss, inflammation of the lungs (pneumonitis), hoarse voice (dysphonia), abnormal liver tests (aspartate aminotransferase increased; alanine aminotransferase increased), night sweats, muscle pain (myalgia), abnormal kidney function tests (blood creatinine increased), painful urination, swelling of the legs (oedema peripheral), and reaction to the infusion of the medicine that can cause fever or flushing. Common side effects include cough, upper respiratory tract infections, feeling tired, shortness of breath, inflammation in the lungs, and rash.

  • Infection (chills, increased temperature)
  • serious lung infections (pneumonia)
  • fungal infection in the mouth
  • tooth and mouth soft tissue infections
  • flu-like illness
  • overactive thyroid gland that can cause fast heart rate or weight loss
  • inflammation of the lungs (pneumonitis)
  • hoarse voice (dysphonia)
  • abnormal liver tests (aspartate aminotransferase increased; alanine aminotransferase increased)
  • night sweats
  • muscle pain (myalgia)
  • abnormal kidney function tests (blood creatinine increased)
  • painful urination
  • swelling of the legs (oedema peripheral)
  • reaction to the infusion of the medicine that can cause fever or flushing
  • Cough
  • upper respiratory tract infections
  • feeling tired
  • shortness of breath
  • inflammation in the lungs
  • rash

Safety Advice for IMFINZI 120MG/2.4ML INJECTIONArrow

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Pregnancy

UNSAFE

IMFINZI 120MG/2.4ML INJECTION is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of IMFINZI 120MG/2.4ML INJECTIONArrow

  • IMFINZI 120MG/2.4ML INJECTION is a prescription medication administered via intravenous injection, meaning it's delivered directly into a vein. This procedure will be performed by a qualified healthcare professional in a hospital or clinical setting. It is crucial not to attempt self-administration of this medicine.
  • Your doctor will determine the appropriate dosage of IMFINZI based on your specific medical condition, overall health, and other individual factors. This ensures you receive the most effective treatment while minimizing potential side effects.
  • Throughout the infusion process, you will be closely monitored by medical staff for any adverse reactions or side effects related to the medication. This allows for immediate intervention if needed. The infusion typically takes several hours to complete, and the treatment plan may involve multiple infusions administered over a period of weeks, as determined by your physician. It is important to adhere to the prescribed schedule for optimal results.
  • Prior to each infusion, inform your doctor about any pre-existing conditions, medications you are currently taking (including over-the-counter drugs and supplements), and any allergies you may have. This information will help the doctor ensure the safe and effective administration of IMFINZI.

How to store IMFINZI 120MG/2.4ML INJECTION?Arrow

  • Keep IMFINZI 120MG INJ 2.4ML away from the reach of children and pets.
  • Store IMFINZI 120MG INJ 2.4ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of IMFINZI 120MG/2.4ML INJECTIONArrow

  • IMFINZI 120MG/2.4ML INJECTION is a targeted immunotherapy that empowers your body's natural defenses to fight cancer. Cancer cells sometimes use a sneaky tactic: they produce a protein called Programmed Death-Ligand 1 (PD-L1) on their surface.
  • This PD-L1 protein acts like a shield, binding to receptors on your immune system's T cells. This binding sends a signal that essentially tells the T cells to ignore the cancer cells, preventing them from attacking and destroying the tumor.
  • IMFINZI 120MG/2.4ML INJECTION works by blocking this PD-L1 protein. By preventing PD-L1 from binding to T cell receptors, the drug removes the 'invisibility cloak' from the cancer cells. This allows your T cells to recognize the cancer cells as a threat.
  • Once the T cells are activated, they can launch an immune response against the cancer, directly attacking and killing the cancer cells. This can lead to a slowing down or even a stopping of cancer growth, offering a significant advantage in the fight against the disease.
  • In essence, IMFINZI 120MG/2.4ML INJECTION unleashes the power of your own immune system to target and destroy cancer cells, offering a powerful and precise approach to cancer treatment.

How to use IMFINZI 120MG/2.4ML INJECTIONArrow

  • IMFINZI 120MG/2.4ML INJECTION is a prescription medication administered via intravenous infusion. This means it is injected directly into a vein in your arm or hand. This procedure will always be performed by a trained healthcare professional in a hospital or clinical setting. It is crucial that you do not attempt to self-administer this medication.
  • Your doctor will determine the precise dosage of IMFINZI 120MG/2.4ML INJECTION based on your specific medical condition, overall health, and other individual factors. They will carefully assess your needs to ensure the treatment is tailored to you.
  • During each infusion, the medical staff will closely monitor you for any potential side effects or reactions to the medication. This allows them to address any concerns promptly and ensure your safety and comfort throughout the process. The infusion can take several hours to complete, and the total treatment plan may involve multiple infusions scheduled over several weeks or months, depending on your condition and response to the therapy. It's essential to adhere to the prescribed schedule to achieve the best possible outcome. Remember to discuss any questions or concerns you have with your healthcare provider.

FAQs

How will I receive IMFINZI 120MG/2.4ML INJECTION?

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IMFINZI 120MG/2.4ML INJECTION is administered intravenously into a vein in your arm or hand by a healthcare professional.

How does IMFINZI 120MG/2.4ML INJECTION work?

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It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system's ability to recognize and attack cancer cells. By blocking the interaction between PD-L1 and its receptor, This medicine allows T cells to recognize and attack cancer cells more effectively. This drug helps the immune system to fight the cancer and potentially slow or stop its growth.

Can IMFINZI 120MG/2.4ML INJECTION be used in combination with other drugs?

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Yes, IMFINZI 120MG/2.4ML INJECTION is often used in combination with other immunotherapy drugs, such as tremelimumab, to boost the immune response against cancer cells.

Whether IMFINZI 120MG/2.4ML INJECTION is safe to use during pregnancy?

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IMFINZI 120MG/2.4ML INJECTION is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Who should not take a IMFINZI 120MG/2.4ML INJECTION?

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This drug is not recommended in patients with autoimmune diseases, such as lupus, rheumatoid arthritis, or multiple sclerosis, who may be at an increased risk of side effects from IMFINZI 120MG/2.4ML INJECTION, and it should be used with caution in these patients.

Does IMFINZI 120MG/2.4ML INJECTION interact with other drugs?

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There is no known interaction of IMFINZI 120MG/2.4ML INJECTION with other drugs.

What advice should I follow for using IMFINZI 120MG/2.4ML INJECTION?

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IMFINZI 120MG/2.4ML INJECTION has the tendency to cause harm to unborn fetus. Inform your healthcare provider before starting this treatment if you are pregnant, or have a partner who can become pregnant. Your healthcare provider will conduct a pregnancy test before you start treatment with this drug. Discuss effective birth control methods with your healthcare provider and use them during treatment and for 8 weeks after your last dose. It is not known if this drug passes into breast milk. Hence, it is not recommended to breastfeed during this treatment. This drug can increase your risk of sunburn and skin damage, so it is important to wear protective clothing and sunscreen while moving outdoors. If you experience any gastrointestinal symptoms, such as diarrhea, abdominal pain, or nausea, be sure to inform your doctor immediately so that he may prescribe you antiemetic medicines also to prevent the symptoms.

What molecule/combination is used for making IMFINZI 120MG/2.4ML INJECTION?

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DURVALUMAB is molecule/combination used for making IMFINZI 120MG/2.4ML INJECTION.

For what ailments/diseases/conditions is IMFINZI 120MG/2.4ML INJECTION prescribed?

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IMFINZI 120MG/2.4ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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AstraZeneca Pharmaceuticals LP, US Food and Drug Administration

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AstraZeneca UK Limited, Electronic medicines compendium (EMC)

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Ema (2022) Imfinzi, European Medicines Agency

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Reviewed on 18-01-2024

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(5/5)


Marketer / Manufacturer Details

ASTRAZENECA PHARMA INDIA LIMITED

Country of Origin -

India

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IMFINZI 120MG/2.4ML INJECTION

IMFINZI 120MG/2.4ML INJECTION

MRP

45500

₹34760

23.6 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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