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INSUMAN COMB 50 PENFILL 3 ML
INSUMAN COMB 50 PENFILL 3 ML
By SANOFI INDIA LIMITED
MRP
₹
333.8
₹283.73
15 % OFF
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Composition
Product Details
About INSUMAN COMB 50 PENFILL 3 ML
- INSUMAN COMB 50 PENFILL 3 ML is a rapid-acting insulin formulation utilized in the management of both type 1 and type 2 diabetes mellitus. It plays a crucial role, alongside a balanced diet and consistent physical activity, in maintaining optimal blood sugar control after meals. This proactive management significantly reduces the risk of severe diabetes-related complications, including kidney damage and vision impairment.
- Typically, INSUMAN COMB 50 PENFILL 3 ML is prescribed in conjunction with a longer-acting insulin or other antidiabetic medications to provide comprehensive glycemic control. Your healthcare provider will provide detailed instructions on the correct subcutaneous injection technique. It is essential to administer the injection 20 to 30 minutes before consuming a meal and to adhere to the prescribed regimen consistently unless otherwise directed by your physician. Remember that this medication is an integral part of a holistic treatment plan, which should encompass a healthy dietary approach, regular exercise, and weight management as advised by your healthcare professional.
- Regular blood sugar monitoring is vital. Maintain a meticulous record of your blood glucose levels and share these readings with your doctor. This information is crucial for determining the appropriate dosage of INSUMAN COMB 50 PENFILL 3 ML tailored to your specific needs. It's also important to understand potential side effects.
- The most frequently observed side effect is hypoglycemia (low blood sugar), which can manifest as injection site reactions, cold sweats, anxiety, tremors, hunger, a rapid heartbeat, headache, and nervousness. Hypoglycemia is more likely to occur if you delay eating after injecting this rapid-acting insulin. To mitigate this risk, always administer the precise prescribed dose, maintain a consistent meal schedule, and monitor your blood sugar levels diligently. Excessive alcohol consumption can also precipitate a drop in blood sugar. Other potential side effects include injection site reactions like redness or swelling. Some individuals may experience weight gain while using insulin therapy.
- Do not administer INSUMAN COMB 50 PENFILL 3 ML if you are experiencing hypoglycemia. Inform your doctor about any pre-existing kidney, liver, or heart conditions before commencing treatment. Pregnant or breastfeeding women should consult their doctor, as dosage adjustments may be necessary.
Uses of INSUMAN COMB 50 PENFILL 3 ML
- Diabetes is a condition where your blood sugar levels become too high; it requires careful management and lifestyle adjustments.
How INSUMAN COMB 50 PENFILL 3 ML Works
- INSUMAN COMB 50 PENFILL 3 ML is a rapid-acting insulin formulation designed to help manage blood sugar levels. Following injection, it typically begins to work within approximately 30 minutes. This medication functions in a similar manner to the natural insulin produced by your body, playing a crucial role in regulating glucose metabolism.
- Insulin's primary function is to facilitate the absorption of sugar (glucose) from the bloodstream into muscle and fat cells. This process provides these cells with the energy they need to function properly. By enabling glucose uptake, INSUMAN COMB 50 PENFILL 3 ML helps to lower blood sugar levels, preventing them from becoming dangerously high.
- In addition to promoting glucose uptake, INSUMAN COMB 50 PENFILL 3 ML also helps to control blood sugar by suppressing the liver's production of glucose. The liver naturally produces glucose, but in individuals with diabetes, this production can be excessive, leading to elevated blood sugar levels. By inhibiting this process, INSUMAN COMB 50 PENFILL 3 ML further contributes to maintaining healthy blood sugar levels throughout the day.
Side Effects of INSUMAN COMB 50 PENFILL 3 ML
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
- Hypoglycemia (low blood glucose level)
- Weight gain
- Injection site reactions (pain, swelling, redness)
- Cold sweat
- Anxiety
- Shakiness
- Hunger pangs
- Fast heart rate
- Headache
- Nervousness
Safety Advice for INSUMAN COMB 50 PENFILL 3 ML

Liver Function
CautionINSUMAN COMB 50 PENFILL 3 ML should be used with caution in patients with liver disease. Dose adjustment of INSUMAN COMB 50 PENFILL 3 ML may be needed. Please consult your doctor.
How to store INSUMAN COMB 50 PENFILL 3 ML?
- Keep INSUMAN COMB 50 PENFILL 3ML away from the reach of children and pets.
- Store INSUMAN COMB 50 PENFILL 3ML in a refrigerator (2 - 8°C). Do not freeze.
Benefits of INSUMAN COMB 50 PENFILL 3 ML
- <b>Diabetes Management with INSUMAN COMB 50 PENFILL 3 ML</b><br>INSUMAN COMB 50 PENFILL 3 ML is a rapid-acting insulin analog designed to help manage blood sugar levels, typically used in conjunction with other diabetes medications. It effectively supplements or replaces the insulin that your body should be producing naturally. This insulin facilitates the movement of glucose from the bloodstream into muscle and fat cells, where it can be used as energy, and also helps to reduce glucose production in the liver.
- By maintaining optimal blood sugar levels, INSUMAN COMB 50 PENFILL 3 ML significantly reduces the risk of long-term diabetes complications, including kidney damage (nephropathy), eye damage (retinopathy), nerve problems (neuropathy), and the potential for limb loss. It is crucial to understand the correct injection technique, including where and when to administer the insulin, to maximize its effectiveness.
- For best results and a healthier life, incorporate INSUMAN COMB 50 PENFILL 3 ML into a consistent routine that includes a balanced diet and regular exercise. Regular monitoring of blood glucose levels is essential to adjust insulin dosages as needed and in consultation with your healthcare provider.
- INSUMAN COMB 50 PENFILL 3 ML starts working faster than regular human insulin. But it may take around 4-5 hours to stop working.
How to use INSUMAN COMB 50 PENFILL 3 ML
- Your doctor or nurse will provide you with detailed instructions on how to use INSUMAN COMB 50 PENFILL 3 ML. It is crucial to follow their guidance precisely to ensure you are administering the correct dose and using the pen device properly. Do not attempt to use the pen until you fully understand the instructions. If you have any questions or uncertainties, do not hesitate to ask your healthcare provider for clarification. They can demonstrate the correct technique and address any concerns you may have.
- Typically, you will need to prime the pen before each injection to ensure proper function and accurate dosing. This involves expelling a small amount of insulin to remove any air bubbles from the needle. Your healthcare provider will show you how to do this correctly. They will also explain how to select the appropriate dose using the pen's dial and how to inject the insulin subcutaneously (under the skin).
- The injection site should be rotated with each injection to prevent skin problems such as lipodystrophy (changes in fat tissue). Your doctor or nurse can advise you on suitable injection sites and how to rotate them effectively. Remember to always use a new needle for each injection to maintain sterility and prevent infection. Proper disposal of used needles is also essential for safety. Your healthcare provider will provide instructions on safe disposal methods, such as using a sharps container.
Quick Tips for INSUMAN COMB 50 PENFILL 3 ML
- Administer INSUMAN COMB 50 PENFILL 3 ML approximately 20 to 30 minutes before consuming a meal to ensure optimal blood sugar control. Consistency in timing relative to meals is crucial for managing your glucose levels effectively.
- Be vigilant about the potential for hypoglycemia (low blood sugar). Familiarize yourself with the symptoms, which include sweating, a rapid heartbeat, feelings of weakness, blurred vision, and headaches. Educate your family and close contacts on how to recognize and respond to these symptoms in case you are unable to assist yourself. Always carry a readily available source of fast-acting sugar, such as glucose tablets or juice.
- The speed at which your body absorbs INSUMAN COMB 50 PENFILL 3 ML can vary depending on the injection site. Injecting into the abdomen generally leads to faster absorption compared to other areas of the body. Consult your healthcare provider for advice on the best injection sites for your individual needs.
- To prevent the development of lipohypertrophy (hard lumps under the skin) and ensure consistent absorption, it is essential to rotate injection sites regularly. Keep a record of where you injected, and systematically move to different locations within the recommended areas. Talk to your doctor or diabetes educator about proper injection techniques and rotation strategies.
- Proper storage is crucial to maintain the efficacy of INSUMAN COMB 50 PENFILL 3 ML. Opened vials or cartridges can be stored at room temperature for up to 4 weeks. Unopened vials must be stored in the refrigerator at a temperature between 2°C and 8°C (36°F-46°F). Always check the expiration date before use and discard any vials or cartridges that have expired or been stored improperly.
- It is important to monitor your blood sugar levels regularly, as directed by your healthcare provider, to ensure that INSUMAN COMB 50 PENFILL 3 ML is effectively managing your diabetes. Keep a log of your blood sugar readings, insulin dosages, and meals to help identify any patterns or trends that may require adjustments to your treatment plan.
- Before using INSUMAN COMB 50 PENFILL 3 ML, carefully read the product label and any accompanying instructions. If you have any questions or concerns about how to use the medication, talk to your doctor or pharmacist.
- Always inform your healthcare provider about any other medications you are taking, including over-the-counter drugs and herbal supplements, as these may interact with INSUMAN COMB 50 PENFILL 3 ML and affect your blood sugar levels.
- If you experience any unexpected side effects or have concerns about your diabetes management, contact your healthcare provider immediately.
FAQs
Will I need INSUMAN COMB 50 PENFILL 3 ML for the rest of my life?

If you are a type 1 diabetes patient, then yes, you have to take INSUMAN COMB 50 PENFILL 3 ML for the rest of your life because your body is unable to produce sufficient insulin. Therefore, you would need INSUMAN COMB 50 PENFILL 3 ML as an external source of insulin. However, if you are a type 2 diabetes patient, sometimes your doctor may ask you to stop INSUMAN COMB 50 PENFILL 3 ML if you are able to manage your diabetes with proper exercise, diet and oral medicines.
Can INSUMAN COMB 50 PENFILL 3 ML be used with other diabetes medicine?

Yes, INSUMAN COMB 50 PENFILL 3 ML can be used alone or in combination with other diabetes medicines like long-acting insulin or oral diabetes medicines, along with proper diet and exercise. Follow your doctor’s advice and treatment plan to get the maximum benefit.
How should INSUMAN COMB 50 PENFILL 3 ML be used?

INSUMAN COMB 50 PENFILL 3 ML is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks. You can then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.
Is INSUMAN COMB 50 PENFILL 3 ML safe to use in pregnancy?

Yes. INSUMAN COMB 50 PENFILL 3 ML is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning pregnancy or breastfeeding before using INSUMAN COMB 50 PENFILL 3 ML. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefits.
Is INSUMAN COMB 50 PENFILL 3 ML safe to use in type 2 diabetes?

Yes, insulin is safe to use in type 2 diabetes if used according to your doctor's advice. Keep monitoring your blood sugar levels regularly as advised. Your dosage may need to be adjusted as per your needs. Follow the lifestyle changes as advised by your doctor. Talk to your doctor about the side effects and ways to prevent and manage them.
What are the side effects of INSUMAN COMB 50 PENFILL 3 ML? How to prevent them?

The side effects of INSUMAN COMB 50 PENFILL 3 ML are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
Can INSUMAN COMB 50 PENFILL 3 ML cause hypoglycemia? How do I prevent it?

Yes, the most common side effect of INSUMAN COMB 50 PENFILL 3 ML is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, do not skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose/glucon-D or fruit juice with you. Take all the medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.
Is INSUMAN COMB 50 PENFILL 3 ML given as an injection into a vein (intravenous)?

Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, INSUMAN COMB 50 PENFILL 3 ML may be given as an injection into a vein (intravenous). However, in such cases, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.
When does the dosage of INSUMAN COMB 50 PENFILL 3 ML need to be changed?

You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant for certain side effects that you may experience while using INSUMAN COMB 50 PENFILL 3 ML. Your doctor will tell you ways to prevent them. These side effects are usually temporary but if they are very severe, you may need dose modifications.
Does INSUMAN COMB 50 PENFILL 3 ML need to be refrigerated?

INSUMAN COMB 50 PENFILL 3 ML needs to be refrigerated before its first use. Unopened cartridges and unused pre-filled pens of Humalog must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use INSUMAN COMB 50 PENFILL 3 ML if it has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if they still contain INSUMAN COMB 50 PENFILL 3 ML.
What is INSUMAN COMB 50 PENFILL 3 ML? How is it made?

INSUMAN COMB 50 PENFILL 3 ML is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.
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Marketer / Manufacturer Details
SANOFI INDIA LIMITED
Country of Origin -
India
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