ISTAMET G IR 50/500/1 TABLET 10'S
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ISTAMET G IR 50/500/1 TABLET 10'S
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ISTAMET G IR 50/500/1 TABLET 10'S

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ISTAMET G IR 50/500/1 TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

132.19

₹112.36

15 % OFF

₹11.24 Only /

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10

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ISTAMET G IR 50/500/1 TABLET 10'S

  • ISTAMET G IR 50/500/1 TABLET is a triple-combination medicine used, together with diet and exercise, to improve blood-sugar control in adults with type 2 diabetes. It contains three active ingredients that lower glucose by different mechanisms — Sitagliptin 50 mg, Metformin Hydrochloride 500 mg and Glimepiride 1 mg — giving comprehensive control when fewer medicines are not enough. The '50/500/1' refers to the amount of each ingredient, and 'IR' means immediate release, so the medicine is released into the bloodstream relatively quickly for control that includes the after-meal period.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors; it works by increasing the release of insulin from the pancreas after meals and reducing the amount of sugar the liver produces. Metformin is a biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin, so cells use glucose more effectively. Glimepiride belongs to the sulfonylurea group; it stimulates the pancreas to release more insulin, helping lower blood sugar. Together, these three ingredients act on several pathways at once for a synergistic effect. People search for this medicine under terms such as sitagliptin metformin glimepiride tablet, triple combination diabetes medicine, type 2 diabetes with three drugs and high blood sugar control.
  • ISTAMET G IR is usually taken by mouth once or twice daily, with meals to reduce stomach upset. It is important to follow your doctor's instructions on dose and timing, and it is usually prescribed when diabetes cannot be controlled with metformin or sitagliptin alone. Regular monitoring of blood sugar and kidney function is recommended, and lifestyle measures — a healthy diet and regular exercise — should be continued throughout.
  • Common side effects may include nausea, diarrhoea, stomach pain and headache. Because it contains glimepiride, low blood sugar (hypoglycaemia) can occur, especially if a meal is missed or with other diabetes medicines, so learn the warning signs — sweating, shakiness, a fast heartbeat and confusion — and keep a fast-acting sugar source handy. In rare cases, more serious effects such as lactic acidosis (from metformin) or pancreatitis (from sitagliptin) can occur, so seek urgent care for deep or rapid breathing, severe weakness, or severe, persistent stomach pain.
  • Before starting ISTAMET G IR, discuss any existing medical conditions and all your medicines with your doctor, especially kidney or liver problems, heart failure or a history of pancreatitis, and mention if you are due for surgery or a scan using contrast dye. Consult your doctor if you are pregnant or breastfeeding. This is a prescription medicine to be used under professional guidance; consistent adherence to your treatment plan — medication, diet and exercise — is key to good control and to preventing long-term complications.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Istamet G IR 50/500/1 Tablet 10's that is Sitagliptin 50 Mg+glimepiride 1 Mg+metformin Hydrochloride 500 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of ISTAMET G IR 50/500/1 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Management of insulin resistance associated with polycystic ovary syndrome (PCOS)

How ISTAMET G IR 50/500/1 TABLET 10'S Works

  • ISTAMET G IR 50/500/1 Tablet is a combination medication containing three active ingredients: Sitagliptin, Metformin, and Glimepiride. Each component works through different mechanisms to lower blood glucose levels in individuals with type 2 diabetes mellitus. This comprehensive approach addresses multiple aspects of the disease.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of incretin hormones released in the gut. These hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), stimulate insulin release from the pancreas when blood glucose levels are high and decrease glucagon secretion (a hormone that raises blood glucose) when blood glucose levels are high or normal. By enhancing incretin activity, sitagliptin helps to regulate blood glucose levels without causing hypoglycemia (low blood sugar) when used alone.
  • Metformin is a biguanide that primarily works by decreasing glucose production in the liver (hepatic gluconeogenesis). It also improves insulin sensitivity in muscle tissue, allowing cells to use glucose more effectively. In addition, metformin slows down the absorption of glucose from the intestines. Unlike some other diabetes medications, metformin does not stimulate insulin release directly, so it carries a lower risk of hypoglycemia when used alone. Metformin is often considered a first-line treatment for type 2 diabetes due to its effectiveness and relatively low cost.
  • Glimepiride is a sulfonylurea. It stimulates the beta cells in the pancreas to release more insulin. Insulin helps glucose enter cells from the bloodstream, thus lowering blood sugar levels. While Glimepiride is effective at lowering blood sugar, it can carry a risk of hypoglycemia, especially if meals are skipped, during exercise, or when used in combination with other medications that lower blood sugar.
  • The combination of Sitagliptin, Metformin, and Glimepiride in ISTAMET G IR provides a synergistic effect. Sitagliptin enhances insulin secretion in a glucose-dependent manner and suppresses glucagon secretion. Metformin reduces hepatic glucose production and improves insulin sensitivity. Glimepiride stimulates insulin release from the pancreas. Together, these three medications work to control blood glucose levels effectively in people with type 2 diabetes, targeting different pathways involved in glucose regulation. This combination is particularly useful when blood sugar is not adequately controlled with diet, exercise, and single or dual therapy.
  • It is important to take ISTAMET G IR as prescribed by your doctor, along with following a healthy diet and exercise program. Regular monitoring of blood glucose levels is necessary to ensure the medication is working effectively and to adjust the dosage as needed. Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shaking, dizziness, and confusion, and know how to treat it. Also, notify your doctor immediately if you experience any unusual or severe side effects.

Side Effects of ISTAMET G IR 50/500/1 TABLET 10'SArrow

Possible side effects of ISTAMET G IR 50/500/1 Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), weakness, headache, dizziness, constipation, skin rash, itching, and in rare cases, lactic acidosis, vitamin B12 deficiency, or liver problems. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for ISTAMET G IR 50/500/1 TABLET 10'SArrow

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Allergies

Allergies

Do not use ISTAMET G IR 50/500/1 TABLET 10'S if you are allergic to it.

Dosage of ISTAMET G IR 50/500/1 TABLET 10'SArrow

  • The dosage of 'ISTAMET G IR 50/500/1 TABLET 10'S' is highly individualized and depends on several factors, including your blood glucose levels, overall health condition, kidney function, and response to treatment. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Do not self-adjust the dosage, as this could lead to adverse effects or ineffective blood sugar control.
  • Typically, 'ISTAMET G IR 50/500/1 TABLET 10'S' is initiated at a low dose to minimize the risk of gastrointestinal side effects associated with metformin, one of its active ingredients. The dosage is then gradually increased based on your glycemic control and tolerance. Your doctor will monitor your blood sugar levels regularly to determine the optimal dosage for you.
  • The usual starting dose might be one tablet once or twice daily, taken with meals. The maximum recommended daily dose should not be exceeded. It's essential to take 'ISTAMET G IR 50/500/1 TABLET 10'S' with food to help reduce stomach upset. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Regular monitoring of kidney function is important while taking 'ISTAMET G IR 50/500/1 TABLET 10'S', especially in elderly patients. Your doctor may adjust the dosage or discontinue the medication if your kidney function deteriorates. It's important to inform your doctor about all other medications you are taking, as some drugs can interact with 'ISTAMET G IR 50/500/1 TABLET 10'S' and affect its efficacy or increase the risk of side effects.
  • Take 'ISTAMET G IR 50/500/1 TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of ISTAMET G IR 50/500/1 TABLET 10'S?Arrow

  • If you miss a dose of ISTAMET G IR 50/500/1 TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ISTAMET G IR 50/500/1 TABLET 10'S?Arrow

  • Keep ISTAMET G IR 50/500/1MG TAB 1X10 away from the reach of children and pets.
  • Store ISTAMET G IR 50/500/1MG TAB 1X10 at room temperature.

Benefits of ISTAMET G IR 50/500/1 TABLET 10'SArrow

  • ISTAMET G IR 50/500/1 Tablet 10'S is a combination medication designed to effectively manage type 2 diabetes mellitus. It combines three active ingredients: sitagliptin, metformin, and glimepiride, each working through different mechanisms to control blood sugar levels. This multi-pronged approach offers comprehensive glycemic control for patients who may not achieve adequate results with a single medication.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the levels of incretin hormones, which stimulate insulin release and decrease glucagon secretion. Insulin helps to move sugar from the blood into cells for energy, while glucagon tells the liver to release stored sugar into the blood. By enhancing insulin and suppressing glucagon, sitagliptin helps lower blood sugar levels, particularly after meals.
  • Metformin is a biguanide that primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of sugar released by the liver and helps cells use insulin more effectively, allowing them to take up more glucose from the bloodstream. Metformin also has a modest effect on reducing intestinal glucose absorption.
  • Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. It works by binding to specific receptors on pancreatic beta cells, triggering the release of insulin, regardless of blood sugar levels. This helps to lower blood sugar levels, especially before meals.
  • The combined action of these three medications provides several key benefits. Firstly, it offers improved glycemic control by targeting multiple pathways involved in blood sugar regulation. Secondly, it simplifies the treatment regimen for patients who would otherwise need to take multiple medications separately. This can improve adherence and overall treatment outcomes.
  • ISTAMET G IR 50/500/1 Tablet 10'S effectively lowers both fasting and postprandial (after-meal) blood sugar levels. This helps to maintain more stable blood sugar levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).
  • By controlling blood sugar levels, ISTAMET G IR 50/500/1 Tablet 10'S helps to reduce the long-term complications of diabetes, such as heart disease, kidney disease, nerve damage (neuropathy), and eye damage (retinopathy). Effective blood sugar management is crucial for preventing or delaying the onset and progression of these complications.
  • ISTAMET G IR 50/500/1 Tablet 10'S is generally well-tolerated, but as with any medication, it can cause side effects. Common side effects may include nausea, diarrhea, abdominal discomfort, and headache. It is important to discuss any potential side effects with your doctor and to follow their instructions carefully.
  • This medication offers a convenient once- or twice-daily dosing schedule, which can improve patient compliance. This simplified regimen can help patients better manage their condition and improve their overall quality of life. Regular monitoring of blood sugar levels and kidney function is important while taking ISTAMET G IR 50/500/1 Tablet 10'S to ensure optimal safety and effectiveness.
  • ISTAMET G IR 50/500/1 Tablet 10'S provides a comprehensive approach to managing type 2 diabetes, offering benefits in terms of glycemic control, simplification of treatment, and reduction of long-term complications. It is important to use this medication under the guidance of a healthcare professional and to follow their recommendations for diet, exercise, and blood sugar monitoring.

How to use ISTAMET G IR 50/500/1 TABLET 10'SArrow

  • ISTAMET G IR 50/500/1 Tablet 10'S should be taken orally, precisely as your doctor prescribes. It is typically recommended to take this medication with meals to minimize the risk of stomach upset. The dosage and frequency will depend on your blood sugar levels and how your body responds to the treatment. Always follow your doctor's instructions carefully and do not adjust the dosage without consulting them.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Consistency is key, so try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is crucial to maintain a healthy lifestyle while taking ISTAMET G IR. This includes following a balanced diet, engaging in regular physical activity, and monitoring your blood sugar levels regularly as directed by your healthcare provider. Inform your doctor about all other medications, supplements, and herbal remedies you are taking to avoid potential drug interactions. Regular check-ups with your doctor are essential to monitor your progress and adjust your treatment plan as needed. Watch out for symptoms of low blood sugar (hypoglycemia) such as sweating, shakiness, rapid heartbeat, dizziness, and hunger. If you experience these, consume a quick source of sugar and seek medical advice.
  • Store ISTAMET G IR 50/500/1 Tablet 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children. If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or abdominal discomfort, consult your doctor promptly.

Quick Tips for ISTAMET G IR 50/500/1 TABLET 10'SArrow

  • Take ISTAMET G IR 50/500/1 Tablet exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood sugar levels and overall health. Consistency is key for optimal results.
  • It is crucial to take ISTAMET G IR 50/500/1 Tablet with meals to help prevent stomach upset and improve the absorption of the medication. This also helps to manage blood sugar levels effectively after eating. Try to take it at the same time each day to maintain a steady level of medication in your system.
  • While taking ISTAMET G IR 50/500/1 Tablet, monitor your blood sugar levels regularly as directed by your doctor. Keeping a record of your blood sugar readings can help you and your healthcare provider adjust your treatment plan as needed. Regular monitoring can also help you understand how different foods and activities affect your blood sugar.
  • ISTAMET G IR 50/500/1 Tablet can sometimes cause low blood sugar (hypoglycemia). Be aware of the symptoms, such as sweating, shaking, rapid heartbeat, and confusion. Carry a source of quick-acting sugar, like glucose tablets or fruit juice, with you at all times to treat low blood sugar immediately. Inform your family and friends about the signs of hypoglycemia and how to assist you if needed.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting ISTAMET G IR 50/500/1 Tablet. Certain medications can interact with this medicine, affecting its effectiveness or increasing the risk of side effects. This includes over-the-counter drugs and even some herbal remedies. A complete medication list helps your doctor manage your treatment safely and effectively.

Food Interactions with ISTAMET G IR 50/500/1 TABLET 10'SArrow

  • ISTAMET G IR 50/500/1 Tablet 10'S should be taken with food to minimize the risk of gastrointestinal side effects such as nausea, vomiting, and diarrhea. Consistent timing with meals is recommended to maintain stable blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis and interfere with blood sugar control. Consult your doctor or pharmacist for specific dietary advice.

FAQs

What is ISTAMET G IR 50/500/1 Tablet used for?Arrow

ISTAMET G IR 50/500/1 Tablet is used to treat type 2 diabetes mellitus in adults, improving blood sugar control when diet and exercise are not enough.

How should I take ISTAMET G IR 50/500/1 Tablet?Arrow

Take ISTAMET G IR 50/500/1 Tablet as prescribed by your doctor. Usually, it is taken with food to avoid stomach upset. Follow the dosage instructions carefully.

What are the common side effects of ISTAMET G IR 50/500/1 Tablet?Arrow

Common side effects include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. Consult your doctor if these persist or worsen.

Can I stop taking ISTAMET G IR 50/500/1 Tablet on my own?Arrow

Do not stop taking ISTAMET G IR 50/500/1 Tablet without consulting your doctor. Suddenly stopping the medication can lead to uncontrolled blood sugar levels.

What should I do if I miss a dose of ISTAMET G IR 50/500/1 Tablet?Arrow

If you miss a dose, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can ISTAMET G IR 50/500/1 Tablet be used during pregnancy or breastfeeding?Arrow

ISTAMET G IR 50/500/1 Tablet is generally not recommended during pregnancy or breastfeeding. Consult your doctor for alternative treatments.

What are the ingredients of ISTAMET G IR 50/500/1 Tablet?Arrow

ISTAMET G IR 50/500/1 Tablet contains Sitagliptin, Metformin, and Glimepiride as active ingredients.

Can ISTAMET G IR 50/500/1 Tablet cause hypoglycemia?Arrow

Yes, ISTAMET G IR 50/500/1 Tablet can cause hypoglycemia, especially when taken with other diabetes medications or if you skip meals. Be aware of the symptoms of low blood sugar.

What should I avoid while taking ISTAMET G IR 50/500/1 Tablet?Arrow

Avoid excessive alcohol consumption, as it can affect blood sugar levels. Also, maintain a healthy diet and exercise regularly.

Does ISTAMET G IR 50/500/1 Tablet interact with other medications?Arrow

Yes, ISTAMET G IR 50/500/1 Tablet can interact with certain medications. Inform your doctor about all the medicines you are taking, including over-the-counter drugs and herbal supplements.

How should ISTAMET G IR 50/500/1 Tablet be stored?Arrow

Store ISTAMET G IR 50/500/1 Tablet at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

What should I do in case of an overdose of ISTAMET G IR 50/500/1 Tablet?Arrow

In case of an overdose, seek immediate medical attention. Symptoms may include severe hypoglycemia.

Can ISTAMET G IR 50/500/1 Tablet affect kidney function?Arrow

In rare cases, ISTAMET G IR 50/500/1 Tablet can affect kidney function, especially in individuals with pre-existing kidney problems. Regular monitoring of kidney function may be required.

Are there any specific dietary recommendations while taking ISTAMET G IR 50/500/1 Tablet?Arrow

Follow a balanced diet with controlled carbohydrate intake. Regular meal timings are important to prevent hypoglycemia.

Can I drive or operate machinery while taking ISTAMET G IR 50/500/1 Tablet?Arrow

ISTAMET G IR 50/500/1 Tablet can cause dizziness or hypoglycemia, which may impair your ability to drive or operate machinery. Exercise caution until you know how the medication affects you.

What is Istamet G Ir 50/500/1 Tablet 10's used for?Arrow

Istamet G Ir 50/500/1 Tablet 10's is used for management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines; and first-line management of type 2 diabetes mellitus, usually alongside diet and exercise. Istamet G Ir 50/500/1 Tablet 10's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG + Sitagliptin 50 MG. Always use Istamet G Ir 50/500/1 Tablet 10's as advised by your doctor.

What is the composition of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Istamet G Ir 50/500/1 Tablet 10's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG + Sitagliptin 50 MG. It is a sulfonylurea antidiabetic; biguanide antidiabetic; and DPP-4 inhibitor antidiabetic.

What are the side effects of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Commonly reported side effects of Istamet G Ir 50/500/1 Tablet 10's include hypoglycaemia (low blood sugar), weight gain, nausea, headache, dizziness; diarrhoea, nausea, abdominal discomfort, metallic taste, loss of appetite — often improve with time or when taken with food; and headache, upper respiratory symptoms, nasal congestion, sore throat. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Istamet G Ir 50/500/1 Tablet 10's is listed at Rs. 112.36 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Istamet G Ir 50/500/1 Tablet 10's?Arrow

Hypoglycaemia can be prolonged and serious, especially in the elderly, with kidney impairment, missed meals or alcohol; Rare but serious risk of lactic acidosis, particularly with kidney impairment, dehydration, acute illness or excess alcohol; and Rare reports of acute pancreatitis — stop and seek care for severe persistent abdominal pain. Tell your doctor about all other medicines you take before starting Istamet G Ir 50/500/1 Tablet 10's.

What is the correct dosage of Istamet G Ir 50/500/1 Tablet 10's?Arrow

The dose of Istamet G Ir 50/500/1 Tablet 10's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Istamet G Ir 50/500/1 Tablet 10's?Arrow

A generic medicine is one with the same active composition as the branded product — for Istamet G Ir 50/500/1 Tablet 10's that is Glimepiride 1 MG + Metformin Hydrochloride 500 MG + Sitagliptin 50 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Istamet G Ir 50/500/1 Tablet 10's.

How does Istamet G Ir 50/500/1 Tablet 10's work?Arrow

Istamet G Ir 50/500/1 Tablet 10's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG + Sitagliptin 50 MG, a sulfonylurea antidiabetic; biguanide antidiabetic; and DPP-4 inhibitor antidiabetic. It is used for management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines.

Is Istamet G Ir 50/500/1 Tablet 10's a prescription medicine?Arrow

Yes. Istamet G Ir 50/500/1 Tablet 10's requires a valid doctor's prescription.

Who is the manufacturer of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Istamet G Ir 50/500/1 Tablet 10's is manufactured by Sun Pharmaceutical Industries Ltd.

What is the dosage form of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Istamet G Ir 50/500/1 Tablet 10's is supplied as a tablet and is taken by the oral route.

What are the benefits of Istamet G Ir 50/500/1 Tablet 10's?Arrow

Istamet G Ir 50/500/1 Tablet 10's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG + Sitagliptin 50 MG. It is used for management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines; and first-line management of type 2 diabetes mellitus, usually alongside diet and exercise. The benefit you get depends on the condition your doctor prescribed Istamet G Ir 50/500/1 Tablet 10's for.

Is Istamet G Ir 50/500/1 Tablet 10's safe to take daily?Arrow

Whether Istamet G Ir 50/500/1 Tablet 10's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Istamet G Ir 50/500/1 Tablet 10's on your own.

When should Istamet G Ir 50/500/1 Tablet 10's be taken — morning or night?Arrow

The timing of Istamet G Ir 50/500/1 Tablet 10's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Istamet G Ir 50/500/1 Tablet 10's without a doctor's consultation?Arrow

No. Istamet G Ir 50/500/1 Tablet 10's is a prescription medicine and should only be taken on a doctor's advice.

Can Istamet G Ir 50/500/1 Tablet 10's be taken during pregnancy or breastfeeding?Arrow

Do not take Istamet G Ir 50/500/1 Tablet 10's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Istamet G Ir 50/500/1 Tablet 10's?Arrow

Check with your doctor before drinking alcohol while taking Istamet G Ir 50/500/1 Tablet 10's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Istamet G Ir 50/500/1 Tablet 10's be stored?Arrow

Store Istamet G Ir 50/500/1 Tablet 10's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

Book Icon

FDA label for Metformin Hydrochloride and Sitagliptin Phosphate combination product. This document provides detailed information on the drug's composition, clinical pharmacology, indications, dosage, contraindications, warnings, precautions, adverse reactions, and drug interactions. This is relevant as ISTAMET G IR 50/500/1 TABLET contains Sitagliptin and Metformin.

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DrugBank entry for Metformin. This database entry offers comprehensive information about Metformin, including its mechanism of action, pharmacokinetics, indications, contraindications, and drug interactions. This is relevant as ISTAMET G IR 50/500/1 TABLET contains Metformin.

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Book Icon

DrugBank entry for Sitagliptin. This database entry provides detailed information about Sitagliptin, its mechanism of action, pharmacokinetics, indications, contraindications, and drug interactions. This is relevant as ISTAMET G IR 50/500/1 TABLET contains Sitagliptin.

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DeFronzo RA, et al. 'Combination therapy with sitagliptin and metformin is superior to monotherapy with either agent alone in patients with type 2 diabetes mellitus'. Diabetes Care. 2011 Jun;34(6):1230-6. This research article discusses the efficacy and safety of combining Sitagliptin and Metformin for treating type 2 diabetes. Relevant as ISTAMET G IR 50/500/1 TABLET contains Sitagliptin and Metformin.

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European Medicines Agency (EMA) Summary of Product Characteristics for Janumet (Sitagliptin/Metformin). This document provides detailed information on the drug's properties, clinical trials, and usage guidelines within the European Union. This is a relevant reference, since Janumet is a combination of Sitagliptin and Metformin.

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Staf behaviour and madicine knowledge was good.

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Nice experience, always!

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Marketer / Manufacturer Details

SUN PHARMACEUTICAL INDUSTRIES LTD

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India

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ISTAMET G IR 50/500/1 TABLET 10'S

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