JARDIANCE MET 12.5/1000MG TABLET 10'S
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JARDIANCE MET 12.5/1000MG TABLET 10'S
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JARDIANCE MET 12.5/1000MG TABLET 10'S

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JARDIANCE MET 12.5/1000MG TABLET 10'S

By BOEHRINGER INGELHEIM INDIA PVT LTD

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About JARDIANCE MET 12.5/1000MG TABLET 10'S

  • JARDIANCE MET 12.5/1000MG TABLET is a prescription medication used to manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: empagliflozin and metformin hydrochloride. Empagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while metformin is a biguanide.
  • Empagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. This allows excess glucose to be eliminated from the body through urine, thereby lowering blood sugar levels. Metformin, on the other hand, reduces glucose production in the liver and improves the body's sensitivity to insulin. Insulin is a hormone that helps glucose get from your blood into your cells for energy.
  • By combining these two medications, JARDIANCE MET offers a dual-action approach to managing type 2 diabetes. It helps lower blood sugar levels through different mechanisms, providing better glycemic control than either medication alone. JARDIANCE MET is typically taken orally, once or twice daily, with meals. The dosage is determined by your doctor based on your individual needs and response to treatment.
  • It's crucial to use JARDIANCE MET exactly as prescribed by your healthcare provider. Regular monitoring of blood sugar levels is also essential to ensure the medication is working effectively. JARDIANCE MET is most effective when used in conjunction with a healthy diet and regular exercise program. Discuss any concerns or side effects with your doctor.
  • JARDIANCE MET 12.5/1000MG TABLET is available in a pack of 10 tablets. This medication is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both empagliflozin and metformin is appropriate.
  • The 12.5/1000mg strength indicates that each tablet contains 12.5mg of empagliflozin and 1000mg of metformin hydrochloride. This combination provides a convenient way to take both medications in a single tablet, simplifying the treatment regimen for many patients.
  • Please note that this information is for general knowledge and does not substitute professional medical advice. Always consult with your doctor or pharmacist for personalized guidance regarding your specific health condition and medication.

Uses of JARDIANCE MET 12.5/1000MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Helps to control blood sugar levels
  • May help reduce the risk of heart disease in adults with type 2 diabetes and established cardiovascular disease
  • Helps prevent complications associated with high blood sugar
  • Used in conjunction with a healthy diet and regular exercise
  • Can be used in obese patients with type 2 diabetes
  • Can be used with other diabetes medications as part of a comprehensive treatment plan

How JARDIANCE MET 12.5/1000MG TABLET 10'S Works

  • JARDIANCE MET 12.5/1000MG TABLET 10'S is a combination medication containing two active ingredients: empagliflozin and metformin hydrochloride. These components work synergistically to effectively manage blood sugar levels in individuals with type 2 diabetes.
  • Empagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. SGLT2 inhibitors work in the kidneys by blocking the reabsorption of glucose back into the bloodstream. When the kidney filters blood, glucose is normally reabsorbed. Empagliflozin prevents this reabsorption. As a result, excess glucose is excreted through urine, thus lowering blood glucose levels. This mechanism is independent of insulin, meaning it can work even if the body isn't producing enough insulin or is resistant to it.
  • Metformin, on the other hand, is a biguanide. It primarily works in the liver to reduce the production of glucose. The liver is capable of producing glucose, even when you are not eating, and this can be a problem for people with diabetes. Metformin suppresses this excess glucose production. In addition, Metformin improves insulin sensitivity in peripheral tissues (like muscles), allowing cells to use glucose more effectively. It also slows down the absorption of glucose from the intestines after meals, preventing sharp spikes in blood sugar.
  • The combination of empagliflozin and metformin in JARDIANCE MET addresses multiple aspects of blood sugar control. Empagliflozin removes excess glucose through the kidneys, while metformin reduces glucose production in the liver, enhances insulin sensitivity, and reduces glucose absorption from the gut. By targeting these different mechanisms, JARDIANCE MET provides more comprehensive blood sugar management than either drug could achieve alone. This dual action helps to lower HbA1c levels (a measure of long-term blood sugar control) and improve overall glycemic control in individuals with type 2 diabetes. Always take JARDIANCE MET as prescribed by your healthcare provider for optimal results.

Side Effects of JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

- Nausea - Vomiting - Diarrhea - Abdominal pain - Loss of appetite - Metallic taste - Hypoglycemia (low blood sugar), especially when used with other diabetes medications like insulin and sulfonylureas - Genital yeast infections (in both men and women) - Urinary tract infections (UTIs) - Increased urination - Thirst - Dehydration - Dizziness - Headache - Lactic acidosis (rare but serious). Symptoms include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat. - Allergic reactions (rash, itching, swelling) - Vitamin B12 deficiency (with long-term use of metformin) - Ketoacidosis (increased ketones in your blood or urine) - Necrotizing fasciitis of the perineum (Fournier's gangrene) - a rare but serious infection - Upper respiratory tract infection

Safety Advice for JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

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Dosage of JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

  • The recommended dosage of JARDIANCE MET 12.5/1000MG TABLET 10'S varies depending on individual patient needs, tolerability, and prior glycemic control. Typically, the starting dose is one tablet once or twice daily, taken with meals to reduce gastrointestinal side effects. The specific strength (12.5/1000mg) indicates the amount of each active ingredient, empagliflozin and metformin, respectively. Your doctor will determine the most appropriate starting dose based on your current medications and blood sugar levels.
  • Dosage adjustments are made gradually, usually in increments, to find the lowest dose that effectively controls your blood sugar without causing unacceptable side effects. The maximum daily dose should not exceed the maximum recommended daily dose of either empagliflozin or metformin, which your healthcare provider will advise you on. It's crucial to adhere to the prescribed dosage and schedule, as inconsistent use can affect the medication's efficacy.
  • It's important to note that JARDIANCE MET is usually part of a comprehensive diabetes management plan that includes diet and exercise. Your doctor will provide specific guidance on these lifestyle modifications. Regular monitoring of blood sugar levels is also essential to assess your response to the medication and guide further dosage adjustments. Never adjust the dosage on your own without consulting your physician. Take 'JARDIANCE MET 12.5/1000MG TABLET 10'S' only as per the prescription by your physician only
  • If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult your doctor or pharmacist if you have any questions about your dosage or how to take JARDIANCE MET.

What if I miss my dose of JARDIANCE MET 12.5/1000MG TABLET 10'S?Arrow

  • If you miss a dose of JARDIANCE MET 12.5/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store JARDIANCE MET 12.5/1000MG TABLET 10'S?Arrow

  • Keep JARDIANCE MET 12.5/1000MG TAB 1X10 away from the reach of children and pets.
  • Store JARDIANCE MET 12.5/1000MG TAB 1X10 at room temperature.

Benefits of JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

  • JARDIANCE MET 12.5/1000MG TABLET 10'S is a combination medication containing empagliflozin and metformin, designed to manage type 2 diabetes effectively. Empagliflozin belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, while metformin is a biguanide. This dual action helps control blood sugar levels through different mechanisms, offering comprehensive glycemic control.
  • One of the primary benefits of JARDIANCE MET is its ability to lower blood sugar levels. Empagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, thereby reducing blood glucose levels. Metformin, on the other hand, decreases glucose production in the liver and improves the body's sensitivity to insulin, allowing cells to use glucose more effectively. The combination of these two drugs results in significant improvements in blood sugar control compared to using either medication alone.
  • Beyond glycemic control, JARDIANCE MET offers cardiovascular benefits. Studies have shown that empagliflozin can reduce the risk of cardiovascular events, such as heart attack and stroke, in patients with type 2 diabetes and established cardiovascular disease. This is a significant advantage, as cardiovascular complications are a leading cause of mortality in diabetic patients. Metformin also contributes to heart health by improving cholesterol levels and reducing inflammation.
  • JARDIANCE MET can also aid in weight management. Empagliflozin promotes the excretion of glucose through urine, which results in a loss of calories. This can lead to modest weight loss in some individuals. Metformin has also been shown to have a mild weight-reducing effect. While JARDIANCE MET is not specifically a weight-loss medication, its potential to assist in weight management can be a welcome benefit for many patients with type 2 diabetes.
  • This medication can also improve blood pressure control. Studies have indicated that empagliflozin can lead to a reduction in systolic blood pressure. This is beneficial for individuals with diabetes who also have hypertension, as managing blood pressure is crucial for preventing cardiovascular and kidney complications.
  • JARDIANCE MET offers a convenient way to manage type 2 diabetes by combining two medications into a single tablet. This can simplify the treatment regimen and improve adherence, as patients only need to take one medication instead of two. Improved adherence can lead to better overall health outcomes.
  • Furthermore, JARDIANCE MET has been shown to have protective effects on the kidneys. Empagliflozin can slow the progression of diabetic kidney disease, a common complication of diabetes. By reducing glucose levels and blood pressure, JARDIANCE MET helps preserve kidney function and reduce the risk of kidney failure.
  • Finally, JARDIANCE MET can lead to improved overall well-being. By effectively managing blood sugar levels, reducing cardiovascular risks, and potentially aiding in weight management and blood pressure control, this medication can help patients with type 2 diabetes lead healthier and more fulfilling lives. It is important to use JARDIANCE MET as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring of blood sugar levels.

How to use JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

  • JARDIANCE MET 12.5/1000MG TABLET 10'S is an oral medication combining two active ingredients designed to help manage blood sugar levels in adults with type 2 diabetes. It should be used in conjunction with diet and exercise to achieve optimal glycemic control. Always take this medication exactly as prescribed by your doctor. Do not exceed the recommended dosage or change the dosing schedule without consulting your healthcare provider.
  • The typical starting dose varies depending on your current medications and individual needs. Your doctor will determine the most appropriate dose for you. JARDIANCE MET 12.5/1000MG is usually taken twice daily, with meals, to minimize stomach upset. Swallow the tablets whole with a full glass of water. Do not crush, chew, or break the tablets.
  • Consistency is key for optimal results. Try to take JARDIANCE MET 12.5/1000MG at the same times each day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's crucial to monitor your blood sugar levels regularly as directed by your doctor or diabetes educator, especially when starting JARDIANCE MET 12.5/1000MG. This will help you and your doctor assess how well the medication is working and adjust your treatment plan if needed. Report any unusual symptoms or side effects to your healthcare provider promptly.
  • Keep JARDIANCE MET 12.5/1000MG stored at room temperature, away from moisture and heat. Do not store it in the bathroom. Keep out of reach of children. It is important to continue following your diet and exercise plan while taking this medication. Regular follow-up appointments with your doctor are essential to monitor your progress and ensure the medication is working effectively.

Quick Tips for JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

  • Take JARDIANCE MET 12.5/1000MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting them, as this can affect your blood sugar levels and overall health. Adherence to the prescribed regimen is crucial for optimal results.
  • It's best to take JARDIANCE MET 12.5/1000MG TABLET 10'S with food to minimize the risk of stomach upset. Metformin, one of the active ingredients, can sometimes cause nausea or diarrhea, and taking it with meals can help alleviate these side effects. Consistent timing with meals is also helpful.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider. This helps you understand how JARDIANCE MET 12.5/1000MG TABLET 10'S is working for you and allows your doctor to make necessary adjustments to your treatment plan. Keep a log of your readings to share during appointments.
  • Stay hydrated by drinking plenty of water throughout the day while taking JARDIANCE MET 12.5/1000MG TABLET 10'S. Adequate hydration supports kidney function and helps your body eliminate excess glucose effectively. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some medications can interact with JARDIANCE MET 12.5/1000MG TABLET 10'S, potentially affecting its efficacy or increasing the risk of side effects. A complete medication list ensures your doctor can make informed decisions about your care.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, dizziness, and confusion. JARDIANCE MET, when combined with other diabetes medications, can increase the risk of hypoglycemia. Carry a source of fast-acting sugar (e.g., glucose tablets, juice) with you and know how to treat a hypoglycemic episode. Discuss your risk of hypoglycemia with your doctor and develop a plan for managing it.
  • Engage in regular physical activity. Exercise helps improve insulin sensitivity and lowers blood sugar levels. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Consult your doctor before starting any new exercise program, especially if you have other health conditions.
  • Follow a balanced diet that is low in sugar and processed foods. A healthy diet is an essential part of managing diabetes. Work with a registered dietitian or certified diabetes educator to develop a meal plan that meets your individual needs and preferences. Focus on whole grains, fruits, vegetables, and lean protein.
  • Avoid excessive alcohol consumption while taking JARDIANCE MET 12.5/1000MG TABLET 10'S. Alcohol can interfere with blood sugar control and increase the risk of side effects, particularly hypoglycemia. If you choose to drink alcohol, do so in moderation and with food.
  • If you are scheduled for any surgery or medical procedure involving contrast dye, inform your doctor that you are taking JARDIANCE MET 12.5/1000MG TABLET 10'S. Metformin may need to be temporarily discontinued to prevent kidney complications related to the contrast dye. Follow your doctor's instructions carefully before and after the procedure.

Food Interactions with JARDIANCE MET 12.5/1000MG TABLET 10'SArrow

  • JARDIANCE MET 12.5/1000MG TABLET 10'S can be taken with or without food. However, it is generally recommended to take it with meals to reduce the risk of stomach upset, which is a common side effect of metformin. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a serious side effect.

FAQs

What is the use of Jardiance Met 12.5/1000mg Tablet?Arrow

Jardiance Met 12.5/1000mg Tablet is used to treat type 2 diabetes mellitus, especially in patients whose blood sugar cannot be controlled by diet and exercise alone.

How does Jardiance Met 12.5/1000mg Tablet work?Arrow

Jardiance Met 12.5/1000mg Tablet is a combination of two medicines, empagliflozin and metformin. Empagliflozin reduces reabsorption of glucose from the kidneys, leading to more glucose being excreted in the urine. Metformin decreases glucose production in the liver and improves insulin sensitivity.

What are the common side effects of Jardiance Met 12.5/1000mg Tablet?Arrow

Common side effects of Jardiance Met 12.5/1000mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, and genital infections.

Is Jardiance Met 12.5/1000mg Tablet safe for the kidneys?Arrow

Jardiance Met 12.5/1000mg Tablet should be used with caution in patients with kidney disease, and is not recommended in patients with severe kidney disease.

How to store Jardiance Met 12.5/1000mg Tablet?Arrow

Store Jardiance Met 12.5/1000mg Tablet at room temperature, away from direct sunlight and moisture.

Does Jardiance Met 12.5/1000mg Tablet cause weight loss?Arrow

Jardiance Met 12.5/1000mg Tablet may cause slight weight loss in some patients, but this is not the primary use of the medication.

Is Jardiance Met 12.5/1000mg Tablet safe during pregnancy?Arrow

The safety of Jardiance Met 12.5/1000mg Tablet during pregnancy has not been established, and it should only be used if the benefit outweighs the risk.

Can Jardiance Met 12.5/1000mg Tablet be taken with alcohol?Arrow

Avoid taking Jardiance Met 12.5/1000mg Tablet with alcohol, as it can increase the risk of lactic acidosis, which is a serious side effect.

What happens if I miss a dose of Jardiance Met 12.5/1000mg Tablet?Arrow

If you miss a dose of Jardiance Met 12.5/1000mg Tablet, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Jardiance Met 12.5/1000mg Tablet interact with other medications?Arrow

Jardiance Met 12.5/1000mg Tablet can interact with certain other medications, such as insulin and some diuretics. It is important to tell your doctor about all the medications you are taking.

What are the symptoms of an overdose of Jardiance Met 12.5/1000mg Tablet?Arrow

Symptoms of an overdose of Jardiance Met 12.5/1000mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, and lactic acidosis.

Is Jardiance Met 12.5/1000mg Tablet safe for children?Arrow

Jardiance Met 12.5/1000mg Tablet is not recommended for use in children.

Can I drive while taking Jardiance Met 12.5/1000mg Tablet?Arrow

Jardiance Met 12.5/1000mg Tablet is unlikely to affect your ability to drive. However, do not drive if you feel dizzy or experience low blood sugar.

What should I tell my doctor before taking Jardiance Met 12.5/1000mg Tablet?Arrow

Before taking Jardiance Met 12.5/1000mg Tablet, tell your doctor if you have kidney or liver disease, heart problems, or any other medical conditions. Also, tell them about all the medications you are taking.

Can Jardiance Met 12.5/1000mg Tablet be taken with or without food?Arrow

Jardiance Met 12.5/1000mg Tablet is generally recommended to be taken with food to minimize the chance of stomach upset.

References

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JARDIANCE (empagliflozin) tablets, Initial U.S. Approval: 2014. See Section 14 Clinical Studies for details on clinical trials involving empagliflozin. This is the FDA label.

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Empagliflozin DrugBank entry. Provides detailed chemical and pharmacological information on empagliflozin, one of the active ingredients in Jardiance Met.

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GLUCOPHAGE (metformin hydrochloride) tablets, for oral use. Full prescribing information; see Section 14 for Clinical Studies. This is the FDA label.

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Metformin DrugBank entry. Provides detailed chemical and pharmacological information on metformin, the other active ingredient in Jardiance Met.

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Jardiance (empagliflozin) EPAR from the European Medicines Agency. Provides detailed scientific assessment and regulatory information.

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RxList entry for Jardiance, providing patient-oriented information and some clinical trial data summaries. Contains references to the primary literature, but summarizes the technical info.

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Empagliflozin: A review of its pharmacology, therapeutic efficacy and safety. Expert Opinion on Drug Metabolism & Toxicology. 2014 Jul;10(7):1031-45. doi: 10.1517/17425255.2014.912484.

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Efficacy and Safety of Empagliflozin Added to Metformin in 780 Patients With Type 2 Diabetes Mellitus. Diabetes Care 2016 Oct; 39(10): 1649-1655. https://doi.org/10.2337/dc15-2172

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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