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JARDIANCE MET 5/500MG TABLET 10'S

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JARDIANCE MET 5/500MG TABLET 10'S

By BOEHRINGER INGELHEIM INDIA PVT LTD

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₹297.5

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About JARDIANCE MET 5/500MG TABLET 10'S

  • JARDIANCE MET 5/500MG TABLET is a prescription medication designed to help adults with type 2 diabetes manage their blood sugar levels. It combines two active ingredients: empagliflozin and metformin hydrochloride, working synergistically to provide comprehensive glycemic control. Empagliflozin belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood, instead allowing the excess glucose to be excreted through urine. This helps to lower blood sugar levels and can also lead to modest weight loss and blood pressure reduction in some individuals.
  • Metformin hydrochloride, on the other hand, is a biguanide that works primarily by reducing the amount of glucose produced by the liver and improving the body's sensitivity to insulin. Insulin is a hormone that helps glucose enter cells for energy. By making the body more responsive to insulin, metformin helps lower blood sugar levels. The combination of empagliflozin and metformin in JARDIANCE MET offers a dual-action approach to managing type 2 diabetes, addressing both glucose reabsorption in the kidneys and glucose production in the liver, as well as insulin sensitivity.
  • JARDIANCE MET is typically taken orally, once or twice daily, with meals to help reduce gastrointestinal side effects associated with metformin. The dosage is determined by your doctor based on your individual needs and response to treatment. It's important to take JARDIANCE MET exactly as prescribed and to follow your doctor's recommendations regarding diet and exercise. This medication is most effective when used in conjunction with a healthy lifestyle, including a balanced diet and regular physical activity. JARDIANCE MET is not suitable for everyone, and it's important to discuss your medical history and any other medications you are taking with your doctor before starting treatment. Potential side effects may include urinary tract infections, yeast infections, nausea, diarrhea, and dehydration. In rare cases, metformin can cause a serious condition called lactic acidosis, so it's important to be aware of the symptoms and seek medical attention immediately if they occur.
  • This medicine is used with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It may also help to reduce the risk of heart attack, stroke, or death in adults with type 2 diabetes who also have heart disease.

Uses of JARDIANCE MET 5/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart disease (in adults with type 2 diabetes)
  • Improving blood sugar control
  • Used in combination with diet and exercise

How JARDIANCE MET 5/500MG TABLET 10'S Works

  • JARDIANCE MET 5/500MG TABLET is a combination medication containing empagliflozin and metformin, designed to manage blood sugar levels in adults with type 2 diabetes, especially when diet and exercise alone aren't sufficient. Each component contributes uniquely to glycemic control.
  • Empagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Empagliflozin works by blocking SGLT2, preventing the kidneys from reabsorbing glucose. This excess glucose is then excreted in the urine, effectively lowering blood sugar levels. This mechanism is also associated with modest weight loss and blood pressure reduction, providing additional cardiovascular benefits.
  • Metformin, on the other hand, is a biguanide that works primarily by reducing glucose production in the liver. It also enhances insulin sensitivity in muscle tissue, allowing cells to utilize glucose more effectively. Furthermore, metformin slows down the absorption of glucose from the intestines, contributing to a more stable blood sugar level after meals. Metformin is a cornerstone medication in type 2 diabetes management due to its effectiveness and generally favorable safety profile.
  • The combination of empagliflozin and metformin provides a dual mechanism of action, addressing different aspects of glucose regulation. Empagliflozin promotes glucose excretion, while metformin reduces glucose production and improves insulin sensitivity. This synergistic effect can lead to better glycemic control compared to using either medication alone. JARDIANCE MET helps to lower A1C (a measure of average blood sugar levels over 2-3 months), reduce fasting plasma glucose, and improve postprandial (after-meal) glucose levels.
  • By reducing blood sugar levels, JARDIANCE MET helps to prevent or delay the long-term complications of diabetes, such as heart disease, kidney disease, nerve damage, and eye damage. It's crucial to remember that JARDIANCE MET is most effective when used in conjunction with a healthy diet and regular exercise program. Individual results may vary, and it's important to follow your doctor's instructions closely and monitor blood sugar levels regularly.

Side Effects of JARDIANCE MET 5/500MG TABLET 10'SArrow

The following side effects have been reported with Jardiance Met (Empagliflozin/Metformin): **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Hypoglycemia (low blood sugar) – especially when used with other diabetes medications like insulin or sulfonylureas * Urinary tract infections (UTIs) * Thirst * Increased urination **Less Common Side Effects:** * Skin reactions (rash, itching, hives) * Lactic acidosis (a serious metabolic condition – seek immediate medical attention if symptoms like weakness, muscle pain, trouble breathing, stomach pain with nausea/vomiting, feeling cold, dizziness, or irregular heartbeat occur) * Ketoacidosis (a serious condition with high levels of ketones in the blood or urine – seek immediate medical attention if symptoms like nausea, vomiting, abdominal pain, confusion, unusual drowsiness, or difficulty breathing occur) * Dehydration * Yeast infections (genital or skin) * Increased cholesterol levels * Vitamin B12 deficiency * Joint pain **Rare Side Effects:** * Pancreatitis (inflammation of the pancreas) * Severe allergic reactions (anaphylaxis) * Kidney problems * Liver problems **Important Considerations:** This is not a complete list of side effects. Consult your doctor or pharmacist for more information. Seek immediate medical attention if you experience any severe or persistent side effects.

Safety Advice for JARDIANCE MET 5/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Jardiance Met 5/500mg Tablet 10'S if you are allergic to it.

Dosage of JARDIANCE MET 5/500MG TABLET 10'SArrow

  • The recommended dosage of JARDIANCE MET 5/500MG TABLET 10'S varies depending on individual patient needs and tolerability, as determined by your physician. Typically, the starting dose is one tablet taken twice daily with meals to reduce gastrointestinal side effects. The maximum daily dose should not exceed the maximum recommended daily dose of empagliflozin (25 mg) and metformin (2000 mg).
  • Your doctor will adjust the dosage based on your blood sugar levels and how well you tolerate the medication. It is crucial to follow your doctor's instructions precisely and not to alter the dosage without consulting them. Regular monitoring of blood glucose levels is essential to determine the effectiveness of the medication and to make any necessary adjustments.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Consistent timing of doses, ideally with meals, optimizes the medication's effect on blood sugar control throughout the day. Take 'JARDIANCE MET 5/500MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of JARDIANCE MET 5/500MG TABLET 10'S?Arrow

  • If you miss a dose of JARDIANCE MET 5/500MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store JARDIANCE MET 5/500MG TABLET 10'S?Arrow

  • Keep JARDIANCE MET 5/500MG TAB 1X10 away from the reach of children and pets.
  • Store JARDIANCE MET 5/500MG TAB 1X10 at room temperature.

Benefits of JARDIANCE MET 5/500MG TABLET 10'SArrow

  • JARDIANCE MET 5/500MG TABLET 10'S is a combination medication containing empagliflozin and metformin, designed to manage type 2 diabetes effectively. It offers a multi-pronged approach to controlling blood sugar levels, leading to significant health benefits.
  • One of the primary benefits is improved glycemic control. Empagliflozin, an SGLT2 inhibitor, helps the kidneys remove excess glucose from the bloodstream through urine. Metformin, on the other hand, reduces glucose production in the liver and enhances insulin sensitivity, allowing cells to utilize glucose more efficiently. This dual action results in lower HbA1c levels, indicating better long-term blood sugar management.
  • Beyond glycemic control, JARDIANCE MET 5/500MG TABLET 10'S offers cardiovascular benefits. Empagliflozin has been shown to reduce the risk of cardiovascular events, such as heart attack and stroke, in patients with type 2 diabetes and established cardiovascular disease. This makes it a valuable option for individuals with both diabetes and heart conditions.
  • Weight management is another potential benefit. Empagliflozin promotes glucose excretion through urine, leading to calorie loss and potential weight reduction. While not a primary weight-loss medication, it can aid in weight management when combined with a healthy diet and exercise. Metformin can also contribute to modest weight loss in some individuals.
  • JARDIANCE MET 5/500MG TABLET 10'S may also offer renal protection. Studies suggest that empagliflozin can slow the progression of kidney disease in individuals with diabetes. This is particularly important, as diabetes is a leading cause of kidney failure.
  • The convenience of a combination tablet simplifies the treatment regimen. Instead of taking two separate medications, patients can take a single tablet, improving adherence and making it easier to manage their condition. Improved adherence leads to better health outcomes.
  • Furthermore, JARDIANCE MET 5/500MG TABLET 10'S can reduce the risk of certain diabetes-related complications. By controlling blood sugar levels and offering cardiovascular and renal protection, it can help prevent or delay the onset of complications such as nerve damage (neuropathy), eye damage (retinopathy), and kidney disease (nephropathy).
  • It's important to note that JARDIANCE MET 5/500MG TABLET 10'S should be used as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and exercise. Regular monitoring of blood sugar levels and kidney function is also essential. Discuss any concerns or potential side effects with your healthcare provider to ensure safe and effective use of this medication.

How to use JARDIANCE MET 5/500MG TABLET 10'SArrow

  • JARDIANCE MET 5/500MG TABLET 10'S is a combination medication containing empagliflozin and metformin, prescribed to manage type 2 diabetes. It's crucial to use this medication as directed by your healthcare provider. Typically, it is taken orally once or twice daily with meals to minimize stomach upset. The specific dosage will depend on your blood sugar levels, kidney function, and other medications you may be taking. Always swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
  • Consistency is key when taking JARDIANCE MET. Try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Before starting JARDIANCE MET, inform your doctor about all your medical conditions, especially kidney or liver problems, heart failure, bladder cancer, or any history of diabetic ketoacidosis. Also, disclose all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, as drug interactions can occur. Regular monitoring of your blood sugar levels and kidney function is essential while taking this medication. Your doctor may adjust your dosage based on these results. It is important to adhere to a healthy diet and exercise regularly while taking JARDIANCE MET to maximize its effectiveness in managing your diabetes. Contact your healthcare provider immediately if you experience any unusual side effects, such as persistent nausea, vomiting, abdominal pain, unusual tiredness, or symptoms of a urinary tract infection.

Quick Tips for JARDIANCE MET 5/500MG TABLET 10'SArrow

  • Take Jardiance Met exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for managing blood sugar levels effectively. This combination medication works best when taken at the same time each day, ideally with meals, to minimize stomach upset and maximize its glucose-lowering effects. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. Jardiance Met can interact with other drugs, potentially altering their effectiveness or increasing the risk of side effects. Pay close attention to symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, or confusion. Carry a source of fast-acting glucose, like glucose tablets or juice, with you at all times to treat hypoglycemia promptly. Conversely, be aware of symptoms of high blood sugar (hyperglycemia), including increased thirst, frequent urination, and blurred vision, and contact your doctor if these occur.
  • Maintain a healthy lifestyle while taking Jardiance Met. This includes following a balanced diet, engaging in regular physical activity, and managing stress effectively. These lifestyle modifications can significantly improve blood sugar control and overall health. Limit your intake of sugary foods and beverages, and focus on consuming whole grains, lean proteins, and plenty of fruits and vegetables. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Regular check-ups with your doctor are essential for monitoring your blood sugar levels, kidney function, and overall health while taking Jardiance Met. Your doctor may adjust your dosage or treatment plan based on your individual needs and response to the medication.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration is important for kidney function and overall health, especially when taking medications that affect blood sugar levels. Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Alcohol can also interact with Jardiance Met and potentially lead to hypoglycemia. Be cautious when driving or operating machinery until you know how Jardiance Met affects you. The medication can cause dizziness or low blood sugar, which could impair your ability to perform these activities safely. If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or urinary tract infections, contact your doctor for advice.
  • Store Jardiance Met at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Follow proper disposal guidelines for unused or expired medication. Regular monitoring of kidney function is particularly important while taking Jardiance Met. The medication can affect kidney function in some individuals, so your doctor will likely monitor your kidney health periodically through blood tests. Report any signs of a urinary tract infection (UTI), such as burning during urination, frequent urination, or blood in the urine, to your doctor promptly. UTIs are a potential side effect of Jardiance Met and require timely treatment to prevent complications. Familiarize yourself with the signs and symptoms of diabetic ketoacidosis (DKA), a serious complication of diabetes, and seek immediate medical attention if you experience symptoms such as nausea, vomiting, abdominal pain, and difficulty breathing.

Food Interactions with JARDIANCE MET 5/500MG TABLET 10'SArrow

  • Taking Jardiance Met with food may help to reduce stomach upset. However, it is important to take it consistently with regards to meals, either always with food or always without food, to maintain consistent blood sugar control. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis.

FAQs

What is Jardiance Met 5/500mg Tablet 10's and what is it used for?Arrow

Jardiance Met 5/500mg Tablet 10's is a combination medicine containing empagliflozin and metformin. It is used to control blood sugar levels in adults with type 2 diabetes when diet and exercise alone are not enough.

How does Jardiance Met 5/500mg Tablet 10's work?Arrow

Jardiance Met works in two ways: Empagliflozin reduces blood sugar by decreasing the reabsorption of glucose by the kidneys, allowing excess glucose to be excreted in the urine. Metformin reduces glucose production in the liver and improves the body's sensitivity to insulin.

What is the usual dosage of Jardiance Met 5/500mg Tablet 10's?Arrow

The dosage is determined by the doctor based on individual needs. It is usually taken twice daily with meals.

Are there any side effects of Jardiance Met 5/500mg Tablet 10's?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and genital infections. If you experience any serious side effects, contact your doctor immediately.

Can Jardiance Met 5/500mg Tablet 10's interact with other medications?Arrow

Yes, Jardiance Met can interact with certain medications, such as insulin, diuretics, and some blood pressure medications. Tell your doctor about all the medications you are taking.

How should Jardiance Met 5/500mg Tablet 10's be stored?Arrow

Store it at room temperature, away from moisture and heat. Keep out of reach of children.

Is Jardiance Met 5/500mg Tablet 10's safe during pregnancy?Arrow

Its safety during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is Jardiance Met 5/500mg Tablet 10's safe during breastfeeding?Arrow

Its safety during breastfeeding has not been established. Consult your doctor before breastfeeding.

What happens if I miss a dose of Jardiance Met 5/500mg Tablet 10's?Arrow

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Jardiance Met 5/500mg Tablet 10's cause weight loss?Arrow

Some people may experience slight weight loss with Jardiance Met, but it is not a prescribed medication for weight loss.

Is Jardiance Met 5/500mg Tablet 10's safe for kidneys?Arrow

Jardiance Met should be used with caution in people with kidney disease. Inform your doctor if you have kidney problems.

Is it safe to drink alcohol with Jardiance Met 5/500mg Tablet 10's?Arrow

Drinking alcohol with Jardiance Met should be avoided as it can increase the risk of low blood sugar and other side effects.

Should Jardiance Met 5/500mg Tablet 10's be taken with food?Arrow

Yes, Jardiance Met should be taken with food to help reduce stomach upset.

Can I use Jardiance Met 5/500mg Tablet 10's instead of Glimepiride?Arrow

Talk to your doctor about using Jardiance Met 5/500mg Tablet 10's or Glimepiride. They will suggest the most suitable medicine for your condition.

What is the difference between Jardiance Met 5/500mg Tablet 10's and Metformin?Arrow

Jardiance Met 5/500mg Tablet 10's is a combination medicine that contains Empagliflozin and Metformin. While Metformin is single medicine

References

Book Icon

JARDIANCE (empagliflozin) tablets, for oral use. Full Prescribing Information. Initial U.S. Approval: 2014. Highlights of Prescribing Information. This document contains information on indications and usage, dosage and administration, contraindications, warnings and precautions, adverse reactions, drug interactions, use in specific populations, and patient counseling information for Jardiance.

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Jardiance (empagliflozin) NDA 205297 Pharmacology Review(s)

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JARDIANCE- empagliflozin tablet, film coated. Label from Boehringer Ingelheim Pharmaceuticals, Inc.

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Empagliflozin. DrugBank Online. A comprehensive database of drug information.

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Jardiance: Summary of Product Characteristics. European Medicines Agency.

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Empagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. Dovepress. Published online 2015 Jun 12. doi: 10.2147/DMSO.S66755

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JARDIANCE (empagliflozin) tablets, for oral use. Revised: 03/2020. Label includes updates/revisions.

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Jardiance (empagliflozin) Drug Information: Description, Mechanism of Action, Pharmacology, Pharmacokinetics/Metabolism, Clinical Studies

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JARDIANCE (empagliflozin) tablets, for oral use. Prescribing Information. Boehringer Ingelheim Pharmaceuticals, Inc.

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FDA - Pharmacology Review(s) NDA 205297. Application Number: 205297. Active Ingredient: Empagliflozin

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DailyMed - JARDIANCE- empagliflozin tablet, film coated

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Empagliflozin: a review of its use in the treatment of type 2 diabetes mellitus. Clin Drug Investig. 2015; 35(6): 319–328. Published online 2015 Jun 12. doi: 10.1007/s40261-015-0291-6

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JARDIANCE MET 5/500MG TABLET 10'S

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