KYRAB D TABLET 10'S

How KYRAB D TABLET 10'S Works

• KYRAB D TABLET 10'S is a combination medicine designed to address gastrointestinal issues related to acidity and acid reflux, particularly when accompanied by nausea and vomiting. It contains two active ingredients: Rabeprazole and Domperidone, each working through a distinct mechanism to provide comprehensive relief.
• Rabeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid produced in the stomach. The cells in the stomach lining, known as parietal cells, contain 'proton pumps' that secrete acid into the stomach lumen. Rabeprazole selectively binds to and inhibits these proton pumps. This inhibition is not immediate; it requires the drug to be activated in the acidic environment of the parietal cell. Once activated, Rabeprazole irreversibly blocks the pump, thus preventing the secretion of hydrochloric acid (HCl). By suppressing acid production, Rabeprazole helps to heal ulcers, relieve symptoms of acid reflux (heartburn and acid regurgitation), and prevent further damage to the esophagus.
• Domperidone, on the other hand, is a prokinetic agent and antiemetic. It primarily functions by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) of the brain, which is responsible for triggering nausea and vomiting. By blocking dopamine, Domperidone reduces the signals that cause these symptoms. Furthermore, Domperidone enhances gastrointestinal motility. It increases the contractions of the stomach and intestines, helping to move food through the digestive tract more quickly. This action is particularly beneficial in conditions like gastroparesis (delayed gastric emptying), where the stomach empties too slowly. By accelerating gastric emptying and coordinating the contractions of the digestive system, Domperidone reduces feelings of fullness, bloating, and nausea.
• The combined action of Rabeprazole and Domperidone addresses multiple facets of acid reflux and associated symptoms. Rabeprazole reduces acid production, preventing damage to the esophagus and relieving heartburn. Domperidone reduces nausea and vomiting while improving gastric motility, thus preventing acid from refluxing into the esophagus. This synergistic effect makes KYRAB D TABLET 10'S effective in managing conditions such as gastroesophageal reflux disease (GERD) with associated nausea or vomiting and other upper gastrointestinal disorders characterized by acid reflux and impaired gastric motility. The reduction in acid also promotes the healing of any existing esophageal damage or ulcers.
• In summary, KYRAB D TABLET 10'S works by reducing acid production in the stomach via Rabeprazole and controlling nausea and vomiting while enhancing gastric motility via Domperidone, offering comprehensive relief from acid reflux and related symptoms.

Common side effects of KYRAB D Tablet may include nausea, vomiting, heartburn, stomach pain, diarrhea, constipation, dry mouth, dizziness, drowsiness, headache, fatigue, blurred vision, and skin rash or itching. Less common but potentially serious side effects include: severe allergic reactions (anaphylaxis) with symptoms like hives, swelling of the face/lips/tongue/throat, difficulty breathing; irregular heartbeat; muscle weakness or spasms; numbness or tingling; changes in mood or behavior (e.g., anxiety, depression); signs of kidney problems (e.g., changes in urine output); and signs of liver problems (e.g., yellowing of the skin/eyes, dark urine, persistent nausea/vomiting). This is not an exhaustive list, and you should consult your doctor if you experience any unusual symptoms while taking KYRAB D Tablet.

• If you miss a dose of KYRAB D TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep KYRAB D TAB 1X10 away from the reach of children and pets.
• Store KYRAB D TAB 1X10 at room temperature.

• Take KYRAB D TABLET 10'S as directed by your doctor, usually 30 minutes before a meal, to maximize its effectiveness. Adhering to the prescribed dosage and timing is crucial for optimal relief from acid reflux and related symptoms.
• If you miss a dose of KYRAB D TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of side effects.
• Inform your doctor about all the medications, supplements, and herbal products you are currently taking before starting KYRAB D TABLET 10'S. This is important to avoid potential drug interactions that could affect the medication's efficacy or increase the risk of adverse effects. Certain medications may need to be adjusted or monitored closely.
• While taking KYRAB D TABLET 10'S, consider making lifestyle adjustments to manage acid reflux. These may include avoiding trigger foods such as spicy, fatty, or acidic items, eating smaller, more frequent meals, maintaining a healthy weight, and avoiding lying down immediately after eating. Elevating the head of your bed can also help reduce nighttime reflux.
• Long-term use of KYRAB D TABLET 10'S may increase the risk of certain side effects, such as vitamin B12 deficiency or bone fractures. Your doctor may recommend regular monitoring or supplements to mitigate these risks. It's important to discuss the potential benefits and risks of long-term use with your healthcare provider and follow their recommendations.

• KYRAB D TABLET 10'S is generally taken before food. Food does not significantly affect the absorption of the drug. However, it is recommended to take it at least 30 minutes before a meal to ensure optimal effectiveness. Avoid taking it immediately after a heavy meal.