LEUCOWEL 15MG INJECTION
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LEUCOWEL 15MG INJECTION
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LEUCOWEL 15MG INJECTION

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LEUCOWEL 15MG INJECTION

By GETWELL ONCOLOGY PVT LTD

MRP

₹

112

₹75

33.04 % OFF

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Product DetailsArrow

About LEUCOWEL 15MG INJECTION

  • LEUCOWEL 15MG INJECTION contains leucovorin calcium, a substance closely related to folic acid, a vital vitamin. It belongs to the class of folic acid analogs and plays a crucial role in mitigating the adverse effects of methotrexate, a medication used in the treatment of specific cancers. It is also a valuable antidote for individuals who have accidentally overdosed on methotrexate or similar drugs. Furthermore, it is used in conjunction with other anticancer agents in the treatment of colorectal cancer, which originates in the colon or rectum. LEUCOWEL 15MG INJECTION also addresses anemia resulting from folic acid deficiency.
  • This medication works by providing the body with a form of folic acid that can be readily used, especially when methotrexate interferes with the body's ability to utilize folic acid effectively. By supplementing with leucovorin calcium, the harmful effects of methotrexate on healthy cells can be minimized, allowing for a more targeted approach to cancer treatment. In cases of overdose, LEUCOWEL 15MG INJECTION helps to restore the balance of folic acid in the body, counteracting the toxic effects of the drug.
  • It is crucial to avoid LEUCOWEL 15MG INJECTION if you have a known allergy to leucovorin calcium, calcium folinate, or any of the other ingredients in the formulation. It is also contraindicated in individuals with specific types of anemia, such as pernicious anemia or megaloblastic anemia, which are characterized by vitamin B12 deficiency. Prior to commencing treatment, inform your healthcare provider about any pre-existing conditions, including anemia, kidney, heart, or liver problems, as well as any medications you are currently taking, particularly those used for seizure management. Immediately report any symptoms such as wheezing, breathing difficulties, skin rash, itching, hives, or swelling of the lips, face, or tongue to your physician.

Uses of LEUCOWEL 15MG INJECTION

  • Addressing Methotrexate Overdose and Toxicity: Comprehensive strategies to manage and mitigate the risks associated with methotrexate overdose, including recognizing symptoms, administering antidotes, and providing supportive care.
  • Preventing the Harmful Effects of Methotrexate or Similar Medications: Strategies to minimize the adverse effects of methotrexate and related drugs, focusing on dosage adjustments, monitoring for side effects, and utilizing protective agents.
  • Colorectal Cancer: Understanding, treating and managing colorectal cancer. This may include information about LEUCOWEL 15MG INJECTION as part of the treatment plan.
  • Anemia: Addressing anemia, including diagnosis, treatment options (potentially involving LEUCOWEL 15MG INJECTION in specific cases), and management strategies to improve red blood cell production and overall health.

Side Effects of LEUCOWEL 15MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for LEUCOWEL 15MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of LEUCOWEL 15MG INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of LEUCOWEL 15MG INJECTIONArrow

  • A qualified physician or nurse specializing in cancer chemotherapy will administer LEUCOWEL 15MG INJECTION to you. This ensures the medication is given safely and effectively. The precise dosage and the length of your treatment will be determined by your doctor, who will carefully consider several factors.
  • These factors include the specific type of cancer you have, how advanced it is, your overall health, and how well your body responds to the medication. Your doctor may also adjust the dose based on any other medications you are taking or any pre-existing medical conditions you have.
  • LEUCOWEL 15MG INJECTION is typically administered either intravenously (directly into a vein) or intramuscularly (directly into a muscle). The method of administration will depend on your specific condition and the recommendations of your doctor. The intravenous route allows the medication to enter the bloodstream quickly, while the intramuscular route allows for a slower, more sustained release of the drug.
  • Throughout your treatment, your doctor will closely monitor your progress and adjust the dosage of LEUCOWEL 15MG INJECTION as needed. Regular blood tests and other evaluations will be performed to assess how well the medication is working and to check for any potential side effects. It's important to attend all scheduled appointments and to communicate any concerns or side effects you experience to your doctor or nurse promptly.

How to store LEUCOWEL 15MG INJECTION?Arrow

  • Keep LEUCOWEL 15MG INJ 5X2ML away from the reach of children and pets.
  • Store LEUCOWEL 15MG INJ 5X2ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of LEUCOWEL 15MG INJECTIONArrow

  • LEUCOWEL 15MG INJECTION is a medication that works against the effects of drugs like methotrexate, which block an enzyme called dihydrofolate reductase. Methotrexate and similar drugs are used to treat certain cancers and autoimmune diseases, but they can also harm healthy cells. LEUCOWEL 15MG INJECTION helps to protect these cells by providing a form of folate that the cells can use, even when dihydrofolate reductase is blocked. This reduces the side effects of the methotrexate.
  • In cases of anemia caused by folic acid deficiency, LEUCOWEL 15MG INJECTION provides the body with the necessary folic acid to produce red blood cells. Folic acid is essential for the formation of DNA and other genetic material in cells, and a lack of it can lead to anemia. By supplying folic acid, LEUCOWEL 15MG INJECTION helps to restore normal red blood cell production and alleviate the symptoms of anemia.
  • LEUCOWEL 15MG INJECTION is also used in combination with the chemotherapy drug 5-fluorouracil (5-FU) to treat colorectal cancer. It enhances the effects of 5-FU by binding to an enzyme called thymidylate synthase, which is important for DNA synthesis. This binding makes 5-FU more effective at blocking DNA synthesis in cancer cells, leading to their death. Essentially, LEUCOWEL 15MG INJECTION acts as a booster for 5-FU, increasing its ability to kill cancer cells.

How to use LEUCOWEL 15MG INJECTIONArrow

  • LEUCOWEL 15MG INJECTION will be administered to you by a trained physician or nurse who specializes in cancer chemotherapy. The dosage and duration of your treatment will be determined by your doctor, taking into account several factors such as the specific type and stage of your disease, its severity, your overall health condition, and how well you respond to the medication. It is crucial to adhere to the prescribed treatment plan and attend all scheduled appointments to ensure the medication's effectiveness and to monitor any potential side effects.
  • The method of administration, whether intravenously (directly into your vein) or intramuscularly (directly into your muscle), will depend on your individual disease condition and the specific characteristics of the medication. Intravenous administration allows the drug to enter your bloodstream directly for rapid distribution throughout your body. Intramuscular administration involves injecting the medication into a muscle, allowing for a slower, more sustained release of the drug into your system.
  • Your healthcare provider will carefully explain the administration process and address any concerns you may have. They will also monitor you closely during and after the injection to ensure your safety and well-being. Do not hesitate to ask any questions you may have about LEUCOWEL 15MG INJECTION or your treatment plan. Open communication with your healthcare team is essential for a successful treatment outcome.

FAQs

Why is LEUCOWEL 15MG INJECTION given 24 hours after methotrexate?Arrow

LEUCOWEL 15MG INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can LEUCOWEL 15MG INJECTION cause swelling?Arrow

LEUCOWEL 15MG INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can LEUCOWEL 15MG INJECTION cause seizures?Arrow

There is no evidence that LEUCOWEL 15MG INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for LEUCOWEL 15MG INJECTION to work?Arrow

LEUCOWEL 15MG INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with LEUCOWEL 15MG INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of LEUCOWEL 15MG INJECTION with other drungsArrow

There is no known interaction of LEUCOWEL 15MG INJECTION with other drugs.

What is the advice related to LEUCOWEL 15MG INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much LEUCOWEL 15MG INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

Which molecule/combination is used for making LEUCOWEL 15MG INJECTION?Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making LEUCOWEL 15MG INJECTION.

For which ailments/diseases/conditions LEUCOWEL 15MG INJECTION is prescribed?Arrow

LEUCOWEL 15MG INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet]

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Ratings & Review

Very good customer approach

Ketan Sarkar

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Reviewed on 20-01-2024

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(5/5)

Good for generic medicine, quality medicine with affordable rate

nitesh vekariya

•

Reviewed on 03-02-2024

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(5/5)

Good experience with best medicine purchase at affordablee prices.

Aman Rohit M

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Reviewed on 05-02-2024

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(5/5)

Genuine products

monalisha satapathy

•

Reviewed on 05-08-2023

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(5/5)

Excellent service & approach

Raju Palkhade

•

Reviewed on 18-01-2024

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(5/5)

Marketer / Manufacturer Details

GETWELL ONCOLOGY PVT LTD

Country of Origin -

India

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LEUCOWEL 15MG INJECTION

LEUCOWEL 15MG INJECTION

MRP

₹

112

₹75

33.04 % OFF

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