LEVOFLOX 500 INFUSION 100 ML
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LEVOFLOX 500 INFUSION 100 ML
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LEVOFLOX 500 INFUSION 100 ML

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LEVOFLOX 500 INFUSION 100 ML

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

156

₹132.6

15 % OFF


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Product DetailsArrow

About LEVOFLOX 500 INFUSION 100 ML

  • LEVOFLOX 500 INFUSION 100 ML contains levofloxacin, a synthetic broad-spectrum antibacterial agent for intravenous administration. Levofloxacin is a fluoroquinolone antibiotic active against a wide range of Gram-positive and Gram-negative bacteria. It functions by inhibiting bacterial topoisomerase IV and DNA gyrase, enzymes essential for DNA replication, transcription, repair, and recombination. This ultimately leads to bacterial cell death.
  • This intravenous formulation is particularly useful for patients who are unable to take oral medication or when a rapid and reliable serum concentration of the antibiotic is required. LEVOFLOX 500 INFUSION is indicated for the treatment of various infections, including pneumonia, bronchitis, urinary tract infections, skin and soft tissue infections, and other susceptible bacterial infections. Its efficacy and broad spectrum make it a valuable tool in combating severe bacterial infections.
  • The 100 ML infusion provides a convenient and precise method of administering the medication. It is crucial to follow the prescribed dosage and administration guidelines provided by a healthcare professional. LEVOFLOX 500 INFUSION should be administered slowly via intravenous infusion to minimize the risk of adverse reactions. As with all antibiotics, it's important to complete the full course of treatment to prevent the development of antibiotic resistance. Regular monitoring by a healthcare provider is essential to ensure the treatment's effectiveness and to manage any potential side effects.
  • LEVOFLOX 500 INFUSION should be used with caution in patients with a history of seizures, tendinitis, or those taking medications that prolong the QT interval. It is also not recommended for use in pregnant or breastfeeding women. Always consult with a healthcare professional before starting any new medication.

Uses of LEVOFLOX 500 INFUSION 100 ML

  • Treatment of Pneumonia
  • Treatment of Bronchitis
  • Treatment of Urinary Tract Infections (UTIs)
  • Treatment of Skin and Soft Tissue Infections
  • Treatment of Prostatic Infections (Prostatitis)
  • Treatment of Acute Sinus Infections
  • Treatment of Certain Sexually Transmitted Infections (STIs)
  • Treatment of Intra-abdominal Infections
  • Treatment of Bone and Joint Infections
  • Treatment After Exposure to Anthrax
  • Treatment of Plague

How LEVOFLOX 500 INFUSION 100 ML Works

  • LEVOFLOX 500 INFUSION 100 ML contains levofloxacin, a synthetic broad-spectrum antibacterial agent belonging to the fluoroquinolone class of antimicrobials. It works by inhibiting bacterial topoisomerase IV and DNA gyrase, enzymes essential for DNA replication, transcription, repair, and recombination in bacteria. By blocking these enzymes, levofloxacin effectively disrupts the bacterial DNA, preventing the bacteria from multiplying and leading to their death.
  • Specifically, DNA gyrase is crucial for the supercoiling of bacterial DNA, a process necessary for packaging the long DNA strands within the bacterial cell. Topoisomerase IV plays a vital role in separating newly replicated DNA during cell division. Levofloxacin preferentially binds to these enzymes, forming stable complexes that interfere with their normal function. This disruption halts bacterial DNA synthesis and ultimately inhibits bacterial growth.
  • The broad-spectrum activity of LEVOFLOX 500 INFUSION 100 ML means it is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as some atypical bacteria. This makes it a valuable treatment option for various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. Because levofloxacin directly targets bacterial DNA processes, it offers a potent mechanism for eradicating bacterial infections, providing relief from symptoms and promoting recovery.
  • When administered intravenously as an infusion, levofloxacin is rapidly distributed throughout the body, reaching high concentrations in various tissues and fluids. This ensures that the drug can effectively target the site of infection. The intravenous route also allows for precise control of the dosage and ensures that the medication is delivered directly into the bloodstream, bypassing the digestive system and achieving optimal therapeutic levels quickly.
  • The effectiveness of levofloxacin is also due to its ability to overcome certain bacterial resistance mechanisms. While some bacteria have developed resistance to other antibiotics, levofloxacin's unique mechanism of action often allows it to remain effective against these resistant strains. However, it is crucial to use levofloxacin judiciously and only when necessary to minimize the development of further resistance. By understanding how levofloxacin works at the molecular level, healthcare professionals can make informed decisions about its use and ensure that patients receive the most appropriate treatment for their bacterial infections. Ultimately, LEVOFLOX 500 INFUSION 100 ML provides a targeted and effective approach to combatting bacterial infections by disrupting their DNA replication processes.

Side Effects of LEVOFLOX 500 INFUSION 100 MLArrow

Possible side effects of LEVOFLOX 500 INFUSION may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, constipation, injection site reactions (pain, redness), elevated liver enzymes. * **Uncommon:** Anxiety, confusion, depression, agitation, tremors, seizures, hallucinations, taste disturbances, visual disturbances, skin rash, itching, urticaria (hives), fungal infections, dyspnea (shortness of breath), weakness, increased sweating, changes in blood sugar levels. * **Rare:** Tendon pain, tendon rupture, peripheral neuropathy (nerve damage), prolongation of the QT interval (a heart rhythm problem), Stevens-Johnson syndrome (a severe skin reaction), toxic epidermal necrolysis (another severe skin reaction), anaphylaxis (severe allergic reaction), liver damage, kidney damage, blood disorders (e.g., anemia, thrombocytopenia), photosensitivity (increased sensitivity to sunlight). **Important Note:** This is not an exhaustive list. Inform your doctor immediately if you experience any unusual or severe side effects.

Safety Advice for LEVOFLOX 500 INFUSION 100 MLArrow

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Allergies

Allergies

Do not use if you are allergic to Levofloxacin or quinolone antibiotics.

Dosage of LEVOFLOX 500 INFUSION 100 MLArrow

  • The recommended dosage of LEVOFLOX 500 INFUSION 100 ML varies depending on the type and severity of the infection being treated, as well as the patient's kidney function. It is crucial to adhere to the dosage prescribed by your physician. The usual dosage for adults with normal kidney function is 500 mg administered intravenously once daily. The infusion should be administered slowly over a period of 60 minutes to minimize the risk of infusion-related reactions.
  • For patients with impaired kidney function, the dosage of LEVOFLOX 500 INFUSION 100 ML may need to be adjusted based on their creatinine clearance. Your doctor will determine the appropriate dosage adjustment based on your individual kidney function. It's important to inform your doctor about any pre-existing kidney conditions before starting treatment with this medication.
  • The duration of treatment with LEVOFLOX 500 INFUSION 100 ML also depends on the type of infection being treated. Treatment duration typically ranges from 7 to 14 days, but may be longer for more severe infections. It is essential to complete the full course of treatment as prescribed by your doctor, even if you start to feel better before the treatment is finished. Stopping treatment prematurely may lead to recurrence of the infection or development of antibiotic resistance.
  • During LEVOFLOX 500 INFUSION 100 ML treatment, patients should maintain adequate hydration by drinking plenty of fluids. This helps to prevent kidney damage and other potential side effects. It is also important to avoid excessive exposure to sunlight, as LEVOFLOX 500 INFUSION 100 ML can increase the risk of sunburn. If you experience any unusual symptoms or side effects during treatment, contact your doctor immediately.
  • Take 'LEVOFLOX 500 INFUSION 100 ML' only as per the prescription by your physician only.

What if I miss my dose of LEVOFLOX 500 INFUSION 100 ML?Arrow

  • As LEVOFLOX 500 INFUSION 100 ML is administered by a healthcare professional, the chances of missing a dose are low. However, if you believe you have missed a dose, inform your doctor or healthcare provider immediately to reschedule the dose as soon as possible. Do not attempt to self-administer or increase the dose to compensate for the missed one.

How to store LEVOFLOX 500 INFUSION 100 ML?Arrow

  • Keep LEVOFLOX 500MG INFUSION 100ML away from the reach of children and pets.
  • Store LEVOFLOX 500MG INFUSION 100ML at room temperature.

Benefits of LEVOFLOX 500 INFUSION 100 MLArrow

  • LEVOFLOX 500 INFUSION 100 ML is a powerful broad-spectrum antibiotic used to treat a wide range of bacterial infections. Its active ingredient, levofloxacin, belongs to the fluoroquinolone class of antibiotics, which are known for their effectiveness against various types of bacteria.
  • One of the primary benefits of LEVOFLOX 500 INFUSION is its ability to combat respiratory tract infections. It is commonly prescribed for conditions such as pneumonia, bronchitis, and sinusitis, where bacterial infection is the underlying cause. Levofloxacin works by inhibiting the bacterial enzymes responsible for DNA replication, effectively stopping the bacteria from multiplying and spreading.
  • LEVOFLOX 500 INFUSION is also highly effective against urinary tract infections (UTIs). UTIs can affect different parts of the urinary system, including the bladder, kidneys, and urethra. Levofloxacin's broad-spectrum activity makes it a suitable choice for treating both simple and complicated UTIs caused by susceptible bacteria.
  • Skin and soft tissue infections are another area where LEVOFLOX 500 INFUSION proves beneficial. These infections can range from minor skin abscesses to more serious conditions like cellulitis. Levofloxacin helps to eradicate the bacteria causing the infection, promoting healing and preventing further complications.
  • In some cases, LEVOFLOX 500 INFUSION may be used to treat bone and joint infections, particularly when caused by susceptible bacteria. These infections can be difficult to treat and often require prolonged antibiotic therapy. Levofloxacin's ability to penetrate bone tissue makes it a valuable option in these situations.
  • Furthermore, LEVOFLOX 500 INFUSION can be used to treat intra-abdominal infections, such as peritonitis. These infections are serious and can be life-threatening, requiring prompt and effective treatment. Levofloxacin's broad spectrum of activity helps to target the various bacteria that may be involved in these infections.
  • LEVOFLOX 500 INFUSION offers the convenience of intravenous administration, which is particularly useful for patients who are unable to take oral medications or who require a higher concentration of the drug in their bloodstream for a faster and more effective response. This makes it suitable for hospitalized patients or those with severe infections.
  • It's important to note that LEVOFLOX 500 INFUSION, like all antibiotics, should only be used to treat bacterial infections. It is not effective against viral infections such as the common cold or flu. Unnecessary use of antibiotics can contribute to antibiotic resistance, which is a growing global health concern. Therefore, it's crucial to use LEVOFLOX 500 INFUSION only when prescribed by a healthcare professional and to complete the full course of treatment as directed, even if symptoms improve before the medication is finished. This helps to ensure that the infection is completely eradicated and reduces the risk of bacteria developing resistance.
  • The infusion form allows for precise dosing and consistent drug levels in the body, optimizing the therapeutic effect. This can be particularly advantageous in patients with impaired absorption or other conditions that may affect the bioavailability of oral medications. LEVOFLOX 500 INFUSION can also be a valuable alternative for patients who experience gastrointestinal side effects from oral antibiotics, as it bypasses the digestive system.
  • LEVOFLOX 500 INFUSION is a valuable tool in the fight against bacterial infections. Its broad-spectrum activity, convenient intravenous administration, and ability to reach various tissues in the body make it an effective treatment option for a wide range of conditions. However, it is essential to use this medication responsibly and under the guidance of a healthcare professional to ensure optimal outcomes and minimize the risk of antibiotic resistance.

How to use LEVOFLOX 500 INFUSION 100 MLArrow

  • LEVOFLOX 500 INFUSION 100 ML is administered intravenously, meaning it's given directly into your vein by a healthcare professional. It's crucial that you do not attempt to self-administer this medication. The infusion will be prepared and administered by a doctor or nurse in a hospital or clinic setting.
  • The dosage and duration of treatment with LEVOFLOX 500 INFUSION 100 ML depend on the type and severity of your infection, as well as your kidney function and overall health. Your doctor will determine the appropriate dose for you. The usual duration of infusion is 60 minutes to minimize the risk of hypotension or other infusion-related reactions. It’s essential to inform your healthcare provider about all your existing medical conditions, especially kidney problems, heart problems, diabetes, or nerve disorders, before starting the infusion.
  • Before the infusion begins, make sure your healthcare provider knows about any medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications can interact with levofloxacin, potentially affecting its efficacy or increasing the risk of side effects. It's particularly important to mention if you are taking blood thinners (like warfarin), NSAIDs (like ibuprofen or naproxen), or medications to control heart rhythm.
  • During the infusion, the healthcare provider will monitor you closely for any signs of adverse reactions, such as changes in heart rate, blood pressure, breathing difficulties, skin rash, or swelling. If you experience any unusual symptoms during or after the infusion, inform your healthcare provider immediately. After the infusion, follow your doctor's instructions carefully. Complete the entire course of treatment, even if you start feeling better, to ensure the infection is fully eradicated and to prevent antibiotic resistance. Staying hydrated is also important; drink plenty of fluids unless your doctor advises otherwise.
  • Levofloxacin can cause side effects like nausea, diarrhea, headache, and dizziness. In rare cases, it can cause more serious side effects, including tendon problems, nerve damage (peripheral neuropathy), and heart rhythm abnormalities. Contact your doctor immediately if you experience severe abdominal pain, muscle weakness, tingling or numbness in your extremities, or palpitations. Avoid prolonged exposure to sunlight during treatment, as levofloxacin can increase your sensitivity to the sun. Use sunscreen and wear protective clothing when outdoors. Store this medicine in a safe place away from children.

Quick Tips for LEVOFLOX 500 INFUSION 100 MLArrow

  • **Understand Your Infection:** LEVOFLOX 500 INFUSION is a powerful antibiotic primarily prescribed for bacterial infections like pneumonia, bronchitis, skin infections, urinary tract infections, and prostatitis. Knowing which infection it's targeting helps you understand its role in your treatment. It works by interfering with the bacteria's DNA, preventing them from multiplying. If you're unsure about the specific infection, always clarify with your doctor or pharmacist.
  • **Proper Administration is Key:** This medication is administered intravenously (IV) by a healthcare professional. The infusion rate and duration are carefully controlled to minimize side effects. Do not attempt to self-administer this medication. If you experience any pain, swelling, or redness at the IV site, inform your nurse or doctor immediately. Ensure the IV line is properly maintained throughout the infusion.
  • **Be Aware of Potential Side Effects:** Like all medications, LEVOFLOX 500 INFUSION can cause side effects. Common ones include nausea, diarrhea, headache, and dizziness. More serious, though less frequent, side effects include tendon pain (tendinitis or tendon rupture), nerve damage (peripheral neuropathy), heart rhythm problems (QT prolongation), and allergic reactions. Report any unusual or persistent symptoms to your healthcare provider promptly. Watch out for signs of an allergic reaction such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing.
  • **Medication Interactions:** LEVOFLOX 500 INFUSION can interact with other medications, potentially affecting how well they work or increasing the risk of side effects. Inform your doctor or pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Specific medications to watch out for include NSAIDs (like ibuprofen), certain heart medications, and blood thinners (like warfarin).
  • **Sun Sensitivity Precautions:** LEVOFLOX 500 INFUSION can increase your sensitivity to the sun. Avoid prolonged sun exposure, tanning beds, and sunlamps while receiving this medication and for several days afterward. Wear protective clothing, use sunscreen with a high SPF (30 or higher), and seek shade when possible. If you experience sunburn, rash, or other skin reactions, contact your doctor.
  • **Hydration is Important:** Maintaining adequate hydration can help minimize some of the side effects associated with LEVOFLOX 500 INFUSION, such as dizziness. Drink plenty of fluids, especially water, throughout the day. However, if you have any fluid restrictions due to underlying medical conditions (like heart failure or kidney disease), consult with your doctor regarding appropriate fluid intake.
  • **Complete the Full Course:** It's crucial to complete the full course of LEVOFLOX 500 INFUSION, even if you start feeling better after a few days. Stopping the medication prematurely can allow the infection to return or become resistant to antibiotics. If you experience severe side effects that make it difficult to complete the course, discuss this with your doctor. They may be able to adjust your dose or switch you to a different medication.
  • **Probiotic Considerations:** Antibiotics like LEVOFLOX 500 INFUSION can disrupt the natural balance of bacteria in your gut, potentially leading to diarrhea or other digestive issues. Consider taking probiotics (such as yogurt with live cultures or probiotic supplements) during and after your treatment to help restore the balance of gut bacteria. However, it is recommended to take probiotics at least 2 hours before or after taking LevoFLOX 500 INFUSION to avoid any interaction. Consult with your doctor or pharmacist to determine the appropriate type and dosage of probiotics for you.

Food Interactions with LEVOFLOX 500 INFUSION 100 MLArrow

  • LEVOFLOX 500 INFUSION 100 ML does not typically have significant interactions with food. It can be administered without regard to meals. However, maintaining consistent eating habits during your treatment course is generally advisable.

FAQs

What is LEVOFLOX 500 INFUSION 100 ML used for?Arrow

LEVOFLOX 500 INFUSION 100 ML is used to treat bacterial infections such as pneumonia, bronchitis, sinus infections, skin infections, and urinary tract infections.

How is LEVOFLOX 500 INFUSION 100 ML administered?Arrow

LEVOFLOX 500 INFUSION 100 ML is administered intravenously (into a vein) by a healthcare professional, usually slowly.

What are the common side effects of LEVOFLOX 500 INFUSION 100 ML?Arrow

Common side effects of LEVOFLOX 500 INFUSION 100 ML include nausea, diarrhea, headache, dizziness, and insomnia.

Is LEVOFLOX 500 INFUSION 100 ML safe for pregnant women?Arrow

It is important to consult with your doctor about the use of LEVOFLOX 500 INFUSION 100 ML during pregnancy, as it may pose a risk to the fetus.

Is LEVOFLOX 500 INFUSION 100 ML safe for breastfeeding women?Arrow

It is important to consult with your doctor about the use of LEVOFLOX 500 INFUSION 100 ML for breastfeeding women, as it may pass into breast milk and affect the infant.

How should LEVOFLOX 500 INFUSION 100 ML be stored?Arrow

LEVOFLOX 500 INFUSION 100 ML should be stored at room temperature, away from direct sunlight and moisture.

Can LEVOFLOX 500 INFUSION 100 ML interact with other medications?Arrow

LEVOFLOX 500 INFUSION 100 ML can interact with certain medications, such as antacids, vitamins, and minerals. It is important to tell your doctor about all the medications you are taking.

What are the symptoms of an overdose of LEVOFLOX 500 INFUSION 100 ML?Arrow

Symptoms of an overdose of LEVOFLOX 500 INFUSION 100 ML may include confusion, dizziness, nausea, vomiting, and seizures.

Is it safe to drink alcohol while taking LEVOFLOX 500 INFUSION 100 ML?Arrow

It is not recommended to drink alcohol while taking LEVOFLOX 500 INFUSION 100 ML, as it may increase the risk of side effects such as dizziness and drowsiness.

What should I do if I miss a dose of LEVOFLOX 500 INFUSION 100 ML?Arrow

If you miss a dose of LEVOFLOX 500 INFUSION 100 ML, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I take other medications with LEVOFLOX 500 INFUSION 100 ML?Arrow

Talk to your doctor or pharmacist before taking other medications with LEVOFLOX 500 INFUSION 100 ML. Some medications can interfere with how LEVOFLOX 500 INFUSION 100 ML works, and this can increase the risk of side effects.

What is the difference between Ciprofloxacin and Levofloxacin?Arrow

Both Ciprofloxacin and Levofloxacin are fluoroquinolone antibiotics, but Levofloxacin is often used at a lower dose and may have a broader spectrum of activity than Ciprofloxacin.

How long does treatment with LEVOFLOX 500 INFUSION 100 ML last?Arrow

The duration of treatment with LEVOFLOX 500 INFUSION 100 ML depends on the type and severity of the infection. Your doctor will determine the length of treatment.

Can LEVOFLOX 500 INFUSION 100 ML treat viral infections?Arrow

No, LEVOFLOX 500 INFUSION 100 ML is an antibiotic and does not treat viral infections like the common cold or flu.

Can LEVOFLOX 500 INFUSION 100 ML cause tendinitis?Arrow

Yes, LEVOFLOX 500 INFUSION 100 ML can cause tendinitis (inflammation of a tendon) or tendon rupture, especially in elderly patients or those taking corticosteroids.

References

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Levofloxacin Injection, solution: Package insert information including composition, usage, and safety data.

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DrugBank entry for Levofloxacin: Comprehensive information on Levofloxacin including its mechanism of action, pharmacokinetics, and therapeutic uses.

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FDA Prescribing Information for Levofloxacin Injection: Official FDA documentation outlining the drug's properties, indications, dosage, and administration.

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Levofloxacin: A Review of Its Use in the Treatment of Bacterial Infections: Article reviewing the use of levofloxacin.

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Comparative safety and efficacy of intravenous levofloxacin and ceftazidime, with or without vancomycin, in the treatment of hospitalized patients with pneumonia.

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Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

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India

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LEVOFLOX 500 INFUSION 100 ML

LEVOFLOX 500 INFUSION 100 ML

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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