LIGNOGESIC GEL 30 GM

How LIGNOGESIC GEL 30 GM Works

• LIGNOGESIC GEL 30 GM is a topical analgesic gel formulated to provide localized pain relief. It combines the synergistic actions of its active ingredients to effectively target and alleviate various types of discomfort, including muscle aches, joint pain, and minor injuries. Here’s a breakdown of how each component contributes to its overall efficacy:
• **Lidocaine (Lignocaine):** Lidocaine is a local anesthetic that works by blocking nerve signals in the body. When applied topically, it penetrates the skin and inhibits the transmission of pain signals from the affected area to the brain. Specifically, lidocaine blocks sodium channels in nerve cell membranes. These channels are essential for the generation and propagation of action potentials, which are the electrical signals that nerves use to communicate. By blocking these channels, lidocaine prevents the nerves from firing and transmitting pain signals, thus providing localized numbness and pain relief.
• **Diclofenac:** Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. It works by inhibiting the production of prostaglandins, which are hormone-like substances that contribute to inflammation, pain, and fever. Diclofenac blocks cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are responsible for converting arachidonic acid into prostaglandins. By inhibiting COX enzymes, diclofenac reduces the synthesis of prostaglandins, thereby reducing inflammation and pain in the treated area.
• **Methyl Salicylate:** Methyl salicylate is a counterirritant that provides a soothing sensation and helps to distract from the underlying pain. It works by causing vasodilation (widening of blood vessels) in the treated area. This increases blood flow to the surface of the skin, creating a warming sensation. This warming effect helps to relieve muscle stiffness and soreness. Additionally, the increased blood flow can help to reduce inflammation by promoting the removal of inflammatory mediators from the affected area. The counterirritant effect also distracts the brain from the deeper pain sensations.
• **Menthol:** Menthol is another counterirritant that produces a cooling sensation. Like methyl salicylate, it helps to distract from the pain. Menthol activates cold-sensitive receptors in the skin, specifically TRPM8 receptors. This activation creates a cooling sensation that can help to relieve pain and discomfort. Additionally, menthol has mild analgesic properties and can help to reduce muscle spasms.
• In summary, LIGNOGESIC GEL 30 GM works through a multi-faceted approach: lidocaine numbs the area by blocking nerve signals, diclofenac reduces inflammation by inhibiting prostaglandin synthesis, and methyl salicylate and menthol provide counterirritant effects that distract from the pain and promote relaxation. The combined effect is a powerful and effective way to manage localized pain and inflammation.

Like all medicines, LIGNOGESIC GEL 30 GM can cause side effects, although not everybody gets them. Common side effects may include: * Application site reactions: redness, itching, burning, or irritation. * Skin rash Uncommon side effects may include: * Allergic reactions: hives, swelling of the face, lips, tongue, or throat. * Numbness or tingling. Rare side effects may include: * Severe allergic reaction (anaphylaxis): difficulty breathing, wheezing, rapid heartbeat, dizziness, or fainting. * Changes in heart rate. * Muscle twitching. If you experience any of these side effects, especially if they are severe or persistent, stop using LIGNOGESIC GEL 30 GM and consult your doctor or pharmacist immediately. This is not an exhaustive list, and other side effects may occur. It's always important to inform your doctor about any side effects you experience while using this medication.

• As this medicine is for external use, missing a dose is unlikely. Use it as per your need.

• Keep LIGNOGESIC GEL 30GM away from the reach of children and pets.
• Store LIGNOGESIC GEL 30GM at room temperature.

• **Use Sparingly and as Directed:** Lignogesic Gel should be applied in a thin layer to the affected area only as needed. Avoid excessive application, as it can increase the risk of side effects. Always follow your doctor's instructions or the directions on the product label.
• **Avoid Contact with Eyes and Mucous Membranes:** Be extremely careful to prevent the gel from coming into contact with your eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse the area thoroughly with cool water immediately.
• **Do Not Apply to Broken or Irritated Skin:** Lignogesic Gel is not suitable for application to broken skin, open wounds, or areas with significant irritation or inflammation. Applying it to these areas can increase absorption and potentially lead to adverse effects.
• **Monitor for Allergic Reactions:** While rare, allergic reactions to lidocaine or other ingredients in the gel are possible. Watch for signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing. Discontinue use and seek medical attention immediately if any of these symptoms occur.
• **Inform Your Doctor About Other Medications:** Before using Lignogesic Gel, inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medicines, and herbal supplements. This is important to prevent potential drug interactions that could affect the gel's efficacy or increase the risk of side effects. Be especially mindful if you are taking other local anesthetics, antiarrhythmics, or medications that affect heart rhythm.

• LIGNOGESIC GEL 30 GM is for external use only and is unlikely to interact with food. However, it is always best to consult your doctor or pharmacist if you have any concerns about potential interactions with food or other medications.