lithosun sr 400mg tablet 10's
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LITHOSUN SR 400MG TABLET 10'S

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LITHOSUN SR 400MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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Product DetailsArrow

Content Reviewed By:

Dr. Amit Patel

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About LITHOSUN SR 400MG TABLET 10'S

  • Lithosun SR is a branded formulation of lithium carbonate in a sustained‑release (SR) tablet form. It is primarily used in the management of bipolar affective disorder, particularly for the prevention and treatment of manic and hypomanic episodes, and as a mood stabilizer in patients with recurrent mood fluctuations. Lithium is one of the oldest and most extensively studied mood stabilizing agents and is often considered when long‑term maintenance therapy is required. The sustained‑release formulation is designed to release lithium gradually over time, which may help reduce peak‑related side effects and allow more stable blood levels when taken as prescribed. Lithium acts on several neurotransmitter systems and intracellular signaling pathways in the brain. Although its exact mechanism of action is not fully understood, it is believed to modulate monoamine neurotransmitters, second messenger systems, and neuroprotective pathways, thereby stabilizing mood and reducing the frequency and severity of mood episodes. Because lithium has a narrow therapeutic index, careful dose titration and regular monitoring of serum lithium levels are essential to maintain efficacy while minimizing toxicity. Lithosun SR is usually prescribed and supervised by psychiatrists or physicians experienced in the use of lithium. Before starting therapy, baseline assessments typically include kidney function tests, thyroid function tests, serum electrolytes, and, in some cases, an electrocardiogram, especially in older adults or those with cardiac risk factors. During treatment, periodic monitoring of serum lithium levels, renal function, and thyroid function is recommended. Patients should be educated about the importance of maintaining adequate fluid intake and stable salt consumption, as dehydration, sudden changes in dietary sodium, or use of certain interacting medicines can significantly alter lithium levels and increase the risk of toxicity. Common adverse effects associated with lithium therapy include tremor, increased thirst, increased urination, mild gastrointestinal upset, weight gain, and a feeling of tiredness. More serious but less common effects include lithium toxicity (manifesting as severe tremor, confusion, ataxia, slurred speech, or seizures), kidney impairment, and thyroid dysfunction (hypothyroidism or, less commonly, hyperthyroidism). Because of these potential risks, Lithosun SR should never be started, stopped, or dose‑adjusted without medical supervision. It is not suitable for everyone; people with significant kidney disease, certain heart conditions, or severe dehydration may not be appropriate candidates for lithium therapy. Women who are pregnant, planning pregnancy, or breastfeeding require individualized risk–benefit assessment and close monitoring if lithium is considered. Patients should promptly report any new neurological symptoms, severe gastrointestinal upset, marked drowsiness, or changes in vision, coordination, or consciousness, as these may indicate emerging toxicity and require urgent medical evaluation.

Uses of LITHOSUN SR 400MG TABLET 10'S

  • Mania is a mental health condition characterized by periods of extreme elation, energy, and sometimes delusions.
  • Bipolar disorder is a mental health disorder that causes extreme mood swings, including both manic (high) and depressive (low) episodes.

How LITHOSUN SR 400MG TABLET 10'S Works

  • LITHOSUN SR 400MG TABLET 10'S is a mood stabilizer that functions by modulating the activity of neurotransmitters in the brain. Neurotransmitters are chemical messengers that facilitate communication between nerve cells. In conditions like bipolar disorder, there can be an imbalance in these neurotransmitters, leading to mood swings.
  • This medication works by stabilizing these neurotransmitter levels, particularly by affecting serotonin and dopamine, which are crucial for regulating mood. It helps to reduce the intensity and frequency of manic episodes (periods of abnormally elevated mood) and depressive episodes (periods of profound sadness or hopelessness).
  • Specifically, LITHOSUN SR 400MG TABLET 10'S acts on nerve cells to reduce excessive excitability. By suppressing this abnormal nerve cell activity, it helps to prevent extreme shifts in mood, promoting a more stable and balanced emotional state. It helps to regulate the electrical activity in the brain, preventing erratic firing of neurons that can contribute to mood disturbances. Ultimately, this contributes to a more balanced and stable mood.

Side Effects of LITHOSUN SR 400MG TABLET 10'SArrow

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

  • Tremors
  • Slurred speech
  • Uncoordinated body movements
  • Nausea
  • Acne
  • Increased white blood cell count
  • Memory impairment
  • Hair loss
  • Goiter (enlarged thyroid gland)
  • Skin rash
  • Increased thirst
  • Weight gain
  • Polyuria
  • Diarrhea
  • Vomiting

Safety Advice for LITHOSUN SR 400MG TABLET 10'SArrow

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Hydration, Electrolytes, and General Precautions

Essential for safe use

Stable fluid and salt intake are crucial for safe lithium therapy, as changes in sodium balance and hydration can significantly affect lithium levels.

How to store LITHOSUN SR 400MG TABLET 10'S?Arrow

  • Keep LITHOSUN SR 400MG TAB 1X10 away from the reach of children and pets.
  • Store LITHOSUN SR 400MG TAB 1X10 at room temperature.

Benefits of LITHOSUN SR 400MG TABLET 10'SArrow

  • <b>Mania</b><br>Mania involves an unusually elevated or excited mood. LITHOSUN SR 400MG TABLET 10'S helps to stabilize mood and soothe nerves, preventing the recurrence of manic symptoms. By taking LITHOSUN SR 400MG TABLET 10'S, individuals can experience improved social interactions and greater ease in performing daily tasks. This medication aids in managing the extreme mood swings associated with mania, allowing for a more balanced and fulfilling life.
  • <b>Bipolar disorder</b><br>LITHOSUN SR 400MG TABLET 10'S functions by re-establishing the normal balance of nerve activity in the brain. This can significantly reduce extreme mood changes and feelings of agitation, leading to fewer episodes of low mood. While it may take several weeks for the medication to take full effect, consistent use is crucial. It is typically prescribed for at least six months, and potentially longer, to maintain its effectiveness. Regular intake is essential, and discontinuation should only occur under medical advice. Complementing the medication with a healthy diet and regular exercise can further alleviate the symptoms of bipolar disorder, promoting overall well-being and stability.

How to use LITHOSUN SR 400MG TABLET 10'SArrow

  • Always adhere to your doctor's instructions regarding the dosage and duration of LITHOSUN SR 400MG TABLET 10'S. It's crucial to follow their guidance for optimal results and to minimize potential side effects. Swallow the tablet whole with a glass of water. Avoid altering its form by chewing, crushing, or breaking it, as this could affect how the medication is released and absorbed into your system. For best results and to enhance absorption, LITHOSUN SR 400MG TABLET 10'S should be taken with food. This can also help to reduce any potential stomach upset.
  • Consistency is key when taking medication. Try to take LITHOSUN SR 400MG TABLET 10'S at the same time each day to maintain a steady level of the drug in your bloodstream. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • If you have any questions or concerns about taking LITHOSUN SR 400MG TABLET 10'S, don't hesitate to reach out to your doctor or pharmacist for clarification. They can provide personalized advice based on your individual health condition and other medications you may be taking. Store LITHOSUN SR 400MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.

FAQs

How quickly does LITHOSUN SR 400MG TABLET 10'S work?Arrow

It takes some time before you see improvement in your symptoms after taking LITHOSUN SR 400MG TABLET 10'S. Though it varies from person to person, it may take 1-3 weeks or longer for you to see the full benefits of LITHOSUN SR 400MG TABLET 10'S. Do not stop taking LITHOSUN SR 400MG TABLET 10'S if you feel you are not improving. Instead, discuss it with your doctor.

Does LITHOSUN SR 400MG TABLET 10'S make you sleepy?Arrow

Yes, LITHOSUN SR 400MG TABLET 10'S can cause nervous system disorders like sleepiness and dizziness and feeling confused. It can also cause rapid eye movements, blurred vision, or blind spots in your eyesight. If you experience any of these symptoms, consult your doctor. In addition, avoid driving or operating heavy machinery as it can be hazardous for you.

Is LITHOSUN SR 400MG TABLET 10'S bad for kidneys?Arrow

Yes, LITHOSUN SR 400MG TABLET 10'S may cause kidney problems. LITHOSUN SR 400MG TABLET 10'S is not prescribed in patients who already have severe kidney impairment. The kidney problems may not be reversible and the symptoms include swollen ankles, passing a lot of urine and feeling thirsty. Before starting treatment with LITHOSUN SR 400MG TABLET 10'S, your doctor will get blood tests done to see if your kidney function is normal. During LITHOSUN SR 400MG TABLET 10'S therapy, any gradual or sudden changes in renal function, even within the normal range, may indicate the need for re-evaluation of treatment.

Can LITHOSUN SR 400MG TABLET 10'S cause gain in weight?Arrow

LITHOSUN SR 400MG TABLET 10'S can cause both weight gain or weight loss. You should keep a check on your weight during LITHOSUN SR 400MG TABLET 10'S therapy. If you feel you are gaining or losing too much weight, consult your doctor who will assess whether the change in weight is due to LITHOSUN SR 400MG TABLET 10'S or some other reason.

What is the most important information I should know about LITHOSUN SR 400MG TABLET 10'S?Arrow

LITHOSUN SR 400MG TABLET 10'S therapy should only be started if adequate facilities for assessing LITHOSUN SR 400MG TABLET 10'S levels are available. This is because LITHOSUN SR 400MG TABLET 10'S toxicity is related to increased levels of LITHOSUN SR 400MG TABLET 10'S in blood. LITHOSUN SR 400MG TABLET 10'S toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your LITHOSUN SR 400MG TABLET 10'S levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.

How should LITHOSUN SR 400MG TABLET 10'S be taken?Arrow

Take LITHOSUN SR 400MG TABLET 10'S exactly as prescribed by your doctor. Check with your doctor if you are not sure. It is meant for oral administration and can be taken with or without food. However, if you start following a certain type of diet, talk to your doctor first. Any drastic changes in the amount of water you drink or amount of sodium (salt) in your diet may require more frequent monitoring of LITHOSUN SR 400MG TABLET 10'S levels.

Which medicines decrease LITHOSUN SR 400MG TABLET 10'S levels?Arrow

You should inform your doctor about the medicines you are taking before starting LITHOSUN SR 400MG TABLET 10'S since many medicines interfere with the working of LITHOSUN SR 400MG TABLET 10'S. Some medicines decrease the levels of LITHOSUN SR 400MG TABLET 10'S in blood which means that it will not work well. These include theophylline (for asthma), caffeine, anything containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea used to treat skin conditions.

What is Lithosun SR and what is it used for?Arrow

Lithosun SR is a sustained‑release tablet containing lithium carbonate, a mood stabilizing medicine. It is mainly used in the management of bipolar affective disorder to treat and prevent manic or hypomanic episodes and to help stabilize mood over the long term. It may also be used in certain other mood or psychiatric conditions at the discretion of a specialist, but its primary indication is bipolar disorder.

How does Lithosun SR work in bipolar disorder?Arrow

Lithosun SR contains lithium, which acts on several chemical signaling systems in the brain. It modulates neurotransmitters such as serotonin, norepinephrine, and dopamine, and influences intracellular second messengers and neuroprotective pathways. These combined effects help reduce abnormal mood swings, decrease the intensity and frequency of manic episodes, and support long‑term mood stabilization. The exact mechanism is complex and not fully understood, but lithium has a well‑established clinical benefit in bipolar disorder.

How should Lithosun SR be taken?Arrow

Lithosun SR should be taken exactly as prescribed by your doctor. The sustained‑release tablets are usually swallowed whole with water and should not be crushed or chewed, as this can alter the release profile and increase the risk of side effects. It is generally taken at the same time each day, with or without food, according to your doctor’s instructions. Never change the dose, frequency, or timing on your own; any adjustments must be guided by your clinician based on clinical response and blood lithium levels.

What monitoring is required while taking Lithosun SR?Arrow

Because lithium has a narrow therapeutic range, regular monitoring is essential. Your doctor will arrange periodic blood tests to measure serum lithium levels, usually after steady state is reached and then at intervals or when doses change, when new interacting medicines are started, or if you develop symptoms suggestive of toxicity. Kidney function (serum creatinine, estimated glomerular filtration rate) and thyroid function (TSH, and sometimes free T4) are also monitored periodically. Additional tests, such as electrolytes or an ECG, may be requested based on your age, comorbidities, and other medicines.

What are common side effects of Lithosun SR?Arrow

Common side effects include fine tremor of the hands, increased thirst (polydipsia), increased urination (polyuria), mild nausea, diarrhea or stomach discomfort, weight gain, and a feeling of tiredness or mild cognitive slowing. Some people may experience dry mouth, acne, or mild swelling. These effects are often dose‑related and may improve as the body adjusts or after dose modification. However, any persistent, troublesome, or worsening symptoms should be discussed with your doctor.

What are signs of lithium toxicity I should watch for?Arrow

Signs of possible lithium toxicity include worsening or coarse tremor, unsteady gait or difficulty walking (ataxia), slurred speech, marked drowsiness, confusion, agitation, muscle twitching, blurred or double vision, severe nausea, vomiting, diarrhea, and, in severe cases, seizures or loss of consciousness. If you develop any of these symptoms, especially if more than one is present, you should seek urgent medical attention and inform healthcare providers that you are taking lithium.

Can I drink alcohol while taking Lithosun SR?Arrow

Alcohol is generally not recommended while taking Lithosun SR. Alcohol can worsen drowsiness, impair judgment, and increase the risk of falls or accidents. It may also contribute to dehydration, which can raise lithium levels and increase the risk of toxicity. If you consume alcohol, it should be only after discussing with your doctor, in limited amounts if permitted, and you should be alert to any change in mood, coordination, or alertness.

Is Lithosun SR safe during pregnancy?Arrow

Lithium use during pregnancy requires careful individual risk–benefit assessment. Lithium has been associated with certain fetal cardiac malformations when used in early pregnancy, although the absolute risk is relatively low. Untreated severe bipolar disorder also carries significant risks for both mother and fetus. Decisions about continuing, stopping, or adjusting Lithosun SR in pregnancy must be made jointly with a psychiatrist and obstetrician. Women who are pregnant or planning pregnancy should not stop lithium abruptly on their own but should seek specialist advice promptly.

Can I breastfeed while taking Lithosun SR?Arrow

Lithium passes into breast milk in clinically significant amounts, and infants are sensitive to its effects. Because of the potential risk of lithium toxicity in the breastfed infant, breastfeeding is usually not recommended while the mother is taking Lithosun SR. In some specialized settings, breastfeeding may be considered with very close monitoring of the infant’s lithium levels, kidney and thyroid function, but this requires expert supervision. Discuss feeding options with your psychiatrist and pediatrician before making a decision.

What medicines or conditions can interact with Lithosun SR?Arrow

Several medicines and medical conditions can affect lithium levels or increase the risk of side effects. Common interacting medicines include certain diuretics (especially thiazides), ACE inhibitors, angiotensin receptor blockers, non‑steroidal anti‑inflammatory drugs (NSAIDs), and some other psychotropic agents. Dehydration, low sodium intake, vomiting, diarrhea, fever, and kidney impairment can all raise lithium levels. Always inform every healthcare provider and pharmacist that you are taking lithium, and do not start or stop any prescription, over‑the‑counter medicine, or herbal supplement without checking for interactions.

What should I do if I miss a dose of Lithosun SR?Arrow

If you miss a dose and remember within a relatively short time, take it as soon as you remember unless it is almost time for your next scheduled dose. If it is close to the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects or toxicity. If you frequently forget doses, discuss strategies with your doctor to improve adherence.

References

Book Icon

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lithium. [Updated 2020 Jan 20] (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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Lithium Carbonate [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals :Ltd.; 2022. (online) Available from:

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LITHOSUN SR 400MG TABLET 10'S

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₹65.35

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