LOSACAR A TABLET 10'S

How LOSACAR A TABLET 10'S Works

• LOSACAR A Tablet 10's is a combination medication containing Losartan and Amlodipine, working synergistically to manage hypertension (high blood pressure). Losartan, an angiotensin II receptor blocker (ARB), selectively blocks the binding of angiotensin II to the AT1 receptor in various tissues, including the vascular smooth muscle and adrenal gland. Angiotensin II is a potent vasoconstrictor; it narrows blood vessels, increasing blood pressure. By blocking its action, Losartan allows blood vessels to relax and widen, reducing blood pressure. It also reduces the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, further contributing to lower blood volume and blood pressure.
• Amlodipine, on the other hand, is a calcium channel blocker. It inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. This inhibition causes relaxation of vascular smooth muscle, leading to vasodilation (widening of blood vessels) and a decrease in peripheral vascular resistance. The reduced resistance makes it easier for the heart to pump blood, thus lowering blood pressure. Amlodipine also has a mild diuretic effect, further aiding in blood pressure reduction.
• The combination of Losartan and Amlodipine provides a more comprehensive approach to blood pressure control compared to using either medication alone. Losartan addresses the hormonal regulation of blood pressure by blocking angiotensin II, while Amlodipine directly relaxes blood vessels by interfering with calcium influx. This dual mechanism of action can be particularly effective for individuals whose hypertension is not adequately controlled by a single agent. The combined effect results in effective blood pressure management, reducing the risk of cardiovascular events such as stroke, heart attack, and kidney damage. The medication should be taken as prescribed by a healthcare professional, with regular monitoring of blood pressure and kidney function to ensure optimal therapeutic outcomes and to detect any potential side effects.

Like all medicines, Losacar A Tablet can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Dizziness * Vertigo (a feeling of spinning) * Low blood pressure * Weakness * Fatigue * Headache * Increased potassium in the blood * Changes in kidney function, including kidney failure in severe cases * Reduced red blood cells (anemia) * Increased blood urea, serum creatinine and serum potassium in patients with heart failure **Uncommon Side Effects (may affect up to 1 in 100 people):** * Sleepiness * Palpitations * Angina pectoris (chest pain) * Shortness of breath (dyspnea) * Abdominal pain * Constipation * Diarrhea * Nausea * Vomiting * Rash * Itching (pruritus) * Swelling (edema) **Rare Side Effects (may affect up to 1 in 1,000 people):** * Hypersensitivity * Angioedema (swelling of the face, lips, tongue, and/or throat) * Elevated liver enzymes * Hepatitis (inflammation of the liver) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Liver dysfunction **Other Possible Side Effects (frequency not known):** * Flu-like symptoms * Back pain * Urinary tract infection * Impotence * Depression * Migraine * Taste disturbances * Ringing in the ears (tinnitus) * Muscle pain * Joint pain * Pancreatitis * Abnormal liver function * Low sodium levels in the blood **Important Note:** This is not an exhaustive list. If you experience any unusual symptoms while taking Losacar A Tablet, consult your doctor or pharmacist.

• If you miss a dose of Losacar A Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for the missed one.

• Keep LOSACAR A TAB 1X10 away from the reach of children and pets.
• Store LOSACAR A TAB 1X10 at room temperature.

• **Consistency is Key:** Take LOSACAR A TABLET 10'S at the same time each day to maintain a steady level of medication in your bloodstream. This helps ensure consistent blood pressure control. Setting a daily alarm can be a useful reminder to avoid missed doses.
• **Dietary Considerations:** While taking LOSACAR A TABLET 10'S, be mindful of your potassium intake. Avoid excessive consumption of potassium-rich foods like bananas, oranges, and spinach unless your doctor advises otherwise. This medication can affect potassium levels, and maintaining a balance is crucial.
• **Hydration Matters:** Stay well-hydrated by drinking plenty of water throughout the day. Proper hydration supports overall cardiovascular health and can help prevent dizziness or lightheadedness, which are potential side effects of blood pressure medications like LOSACAR A TABLET 10'S.
• **Monitor Your Blood Pressure Regularly:** Even while on medication, regularly monitor your blood pressure at home and keep a log to share with your doctor. This helps track the effectiveness of LOSACAR A TABLET 10'S and allows for timely adjustments to your treatment plan if needed. Use a validated blood pressure monitor and follow your doctor's instructions for accurate readings.
• **Lifestyle Modifications:** Complement LOSACAR A TABLET 10'S with healthy lifestyle changes. Engage in regular physical activity (at least 30 minutes of moderate-intensity exercise most days of the week), maintain a balanced diet low in sodium and saturated fats, and manage stress through relaxation techniques like yoga or meditation. These changes can significantly improve your blood pressure and overall well-being. Also, avoid smoking and limit alcohol consumption, as these can negatively impact blood pressure control.

• LOSACAR A TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of this medication. However, it is advisable to take it at the same time each day to maintain consistent blood levels and to help you remember to take it regularly. If you experience any stomach upset, taking it with food may help.