MAGADOL ORAL SUSPENSION 60 ML

How MAGADOL ORAL SUSPENSION 60 ML Works

• MAGADOL ORAL SUSPENSION 60 ML is a carefully formulated medication designed to alleviate pain and reduce fever, particularly in children. Its effectiveness stems from the synergistic action of its active ingredient, typically paracetamol (acetaminophen). Paracetamol works primarily by inhibiting the production of prostaglandins in the brain and spinal cord. Prostaglandins are substances that contribute to pain and inflammation. By reducing prostaglandin synthesis, paracetamol effectively diminishes pain signals and lowers the body's temperature.
• Specifically, paracetamol inhibits cyclooxygenase (COX) enzymes, which are crucial for prostaglandin synthesis. While it's a potent inhibitor of COX in the central nervous system, its effect on COX enzymes in peripheral tissues is weaker. This explains why paracetamol is more effective at reducing fever and pain than at reducing inflammation in the body.
• When a child experiences pain or fever, the body's natural response involves the release of prostaglandins. These substances sensitize nerve endings, making them more responsive to pain signals, and also influence the hypothalamus, the brain region responsible for regulating body temperature. Paracetamol, upon ingestion, is absorbed into the bloodstream and readily crosses the blood-brain barrier, allowing it to exert its effects within the central nervous system.
• By inhibiting COX enzymes in the brain, paracetamol reduces the production of prostaglandins. This, in turn, decreases the sensitivity of nerve endings, thereby alleviating pain. Simultaneously, the reduced prostaglandin levels in the hypothalamus help to reset the body's thermostat, leading to a reduction in fever. The oral suspension formulation ensures that the medication is easily administered and absorbed, making it suitable for children who may have difficulty swallowing tablets.
• The precise mechanism of action of paracetamol is still a subject of ongoing research, but the prevailing understanding is that its effects are primarily mediated through the central nervous system. It's also believed that paracetamol may influence other pain pathways and neurotransmitter systems, contributing to its overall analgesic and antipyretic effects. MAGADOL ORAL SUSPENSION provides effective relief from pain and fever by targeting prostaglandin synthesis in the central nervous system, making it a valuable tool in managing these symptoms in pediatric patients.

Like all medicines, MAGADOL ORAL SUSPENSION 60 ML can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Stomach pain * Diarrhea * Constipation * Heartburn **Uncommon side effects (may affect up to 1 in 100 people):** * Headache * Dizziness * Skin rash * Itching * Hives * Anxiety * Difficulty sleeping **Rare side effects (may affect up to 1 in 1,000 people):** * Serious allergic reactions (anaphylaxis) with symptoms such as swelling of the face, lips, tongue, or throat, difficulty breathing, and/or shock. * Liver problems (e.g., jaundice, hepatitis) * Kidney problems * Blood disorders (e.g., anemia, thrombocytopenia, leukopenia) * Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis) **Very rare side effects (may affect up to 1 in 10,000 people):** * Hallucinations * Confusion **If you experience any of the following, stop taking MAGADOL ORAL SUSPENSION 60 ML and seek immediate medical attention:** * Signs of an allergic reaction * Signs of liver problems (e.g., yellowing of the skin or eyes, dark urine, pale stools, persistent nausea or vomiting) * Signs of kidney problems (e.g., changes in urine output, swelling of the ankles or feet) * Severe skin reactions * Unexplained bleeding or bruising This is not a complete list of side effects. If you experience any other unusual symptoms, talk to your doctor or pharmacist.

• If you miss a dose of Magadol Oral Suspension, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep MAGADOL SUSPENSION 60ML away from the reach of children and pets.
• Store MAGADOL SUSPENSION 60ML at room temperature.

• Shake Well Before Use: Always shake the MAGADOL ORAL SUSPENSION 60 ML bottle well before each use. This ensures that the medication is evenly distributed, providing a consistent and accurate dose every time. Uneven distribution can lead to under-dosing or over-dosing, affecting its effectiveness and safety.
• Accurate Dosage is Key: Use the provided measuring device (oral syringe or measuring cup) to administer the correct dose. Household spoons are not accurate and can lead to incorrect dosing. Consult your doctor or pharmacist if you are unsure about the right dosage for your child based on their weight and age.
• Administer with Food or Milk: If the medicine causes stomach upset, give MAGADOL ORAL SUSPENSION 60 ML with food or milk. This can help reduce the irritation to the stomach lining and make it easier for your child to tolerate the medication. However, always follow your doctor's advice.
• Storage Matters: Store MAGADOL ORAL SUSPENSION 60 ML at room temperature, away from direct sunlight, heat, and moisture. Keep it out of reach of children. Proper storage helps maintain the medication's effectiveness and prevents accidental ingestion.
• Monitor for Side Effects: While MAGADOL ORAL SUSPENSION 60 ML is generally safe, monitor your child for any potential side effects such as allergic reactions (rash, itching, swelling), stomach upset, or drowsiness. If you notice any unusual symptoms, contact your doctor immediately. Never exceed the recommended dose.

• MAGADOL ORAL SUSPENSION 60 ML can be taken with or without food. However, if you experience stomach upset, taking it with food may help.
• Avoid taking it with large amounts of high-fiber foods as they can interfere with the absorption of the medicine.