MATINY 400 TABLET 10'S

How MATINY 400 TABLET 10'S Works

• MATINY 400 TABLET 10'S contains Imatinib, a tyrosine kinase inhibitor. This medication is designed to target and block specific enzymes, known as tyrosine kinases, that are crucial for the growth and spread of certain cancer cells. By inhibiting these enzymes, MATINY 400 TABLET 10'S effectively disrupts the signaling pathways that promote uncontrolled cell division and proliferation in various types of cancers, including chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GIST), and other rare cancers.
• In chronic myeloid leukemia (CML), the Philadelphia chromosome leads to the formation of the BCR-ABL tyrosine kinase, which is constitutively active and drives the uncontrolled growth of myeloid cells. Imatinib specifically binds to the ATP-binding site of the BCR-ABL tyrosine kinase, preventing it from phosphorylating its target proteins. This inhibition effectively shuts down the downstream signaling pathways, such as the STAT, MAPK, and PI3K pathways, which are essential for cell survival, proliferation, and differentiation. As a result, the growth of CML cells is suppressed, and they undergo apoptosis (programmed cell death).
• In gastrointestinal stromal tumors (GISTs), mutations in the KIT or PDGFRA tyrosine kinase receptors are common. These mutations lead to the constitutive activation of the receptor, promoting tumor growth. Imatinib also inhibits the KIT and PDGFRA tyrosine kinases, thereby blocking the signaling pathways that drive GIST cell proliferation and survival. By inhibiting these kinases, Imatinib reduces tumor size, prevents metastasis, and improves patient outcomes.
• Furthermore, Imatinib can also inhibit other tyrosine kinases like ABL, ARG, and certain receptor tyrosine kinases, contributing to its efficacy in various other cancers. Its targeted action minimizes harm to normal cells, reducing the severity of side effects compared to traditional chemotherapy. The drug is administered orally and is absorbed into the bloodstream, reaching the tumor cells and exerting its inhibitory effects. Regular monitoring and dosage adjustments may be required based on individual patient response and tolerance. Overall, MATINY 400 TABLET 10'S works by selectively inhibiting specific tyrosine kinases, disrupting cancer cell signaling, and promoting cell death, leading to disease control and improved patient outcomes.
• In summary, MATINY 400 TABLET 10'S works by targeting specific tyrosine kinases that fuel the growth of cancer cells. By blocking these enzymes, the medicine cuts off the signals that tell the cells to multiply uncontrollably. This helps to slow down or stop the progression of the disease, giving patients a better chance at managing their condition and improving their quality of life. It is essential to take this medication exactly as prescribed by your healthcare provider to achieve the best possible results. Always consult your doctor for any questions or concerns regarding your treatment.

Common side effects of Matiny 400 Tablet may include nausea, vomiting, diarrhea, abdominal pain, fatigue, muscle cramps, skin rash, and edema (swelling). Less common but potentially serious side effects include liver problems (such as jaundice or elevated liver enzymes), heart problems (such as heart failure or irregular heartbeat), kidney problems, bleeding, infections, and severe skin reactions. Other possible side effects are decreased blood cell counts (anemia, leukopenia, thrombocytopenia), loss of appetite, changes in taste, headache, dizziness, insomnia, peripheral neuropathy, and respiratory problems. This is not an exhaustive list, and it's crucial to consult with your doctor or pharmacist for a complete understanding of potential side effects and their management.

• If you miss a dose of MATINY 400 Tablet, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed.

• Keep MATINY 400 TAB 1X10 away from the reach of children and pets.
• Store MATINY 400 TAB 1X10 at room temperature.

• Take MATINY 400 exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this could affect the effectiveness of the treatment and potentially lead to serious health consequences. This ensures optimal therapeutic outcomes and minimizes the risk of complications.
• MATINY 400 should be taken with food to enhance absorption and reduce the risk of gastrointestinal side effects such as nausea, vomiting, or stomach upset. Consistently taking it with meals helps maintain stable blood levels of the medication and improves tolerability. Make sure to take it with a substantial meal.
• It is crucial to maintain consistent dosing intervals for MATINY 400, ideally taking it at the same time each day. This helps maintain a steady concentration of the drug in your system, which is essential for its efficacy. Use a timer or other reminder system to avoid missing doses.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting MATINY 400. Drug interactions can significantly impact the effectiveness and safety of MATINY 400. Some medications may increase or decrease its levels in your body, leading to adverse effects or reduced efficacy. Be especially cautious about drugs that affect liver enzymes.
• Regular monitoring of blood counts and liver function is essential while taking MATINY 400. These tests help to detect any potential side effects early on, allowing for timely intervention and adjustment of the treatment plan. Adhere to your doctor's schedule for blood tests and other necessary evaluations to ensure your safety and the effectiveness of the treatment. If you experience any unusual symptoms such as fatigue, jaundice, or easy bleeding, contact your doctor immediately.
• Store MATINY 400 tablets in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage helps maintain the integrity and efficacy of the drug. Do not use MATINY 400 if the tablets appear damaged or discolored.

• MATINY 400 TABLET 10'S should be taken with food to improve absorption and reduce the risk of gastrointestinal side effects.
• Avoid consuming grapefruit or grapefruit juice while taking this medication, as it can significantly increase the concentration of imatinib in your blood, potentially leading to increased side effects.
• Maintain a consistent diet while on MATINY 400 TABLET 10'S. Significant changes in your diet may affect the absorption and effectiveness of the medication.
• If you experience nausea or stomach upset, try taking the medication with smaller, more frequent meals.
• Consult your doctor or pharmacist if you have specific dietary concerns or restrictions while taking MATINY 400 TABLET 10'S.