MAXBRIM PF BAK FREE SUSPENSION 5 ML

How MAXBRIM PF BAK FREE SUSPENSION 5 ML Works

• MAXBRIM PF BAK FREE SUSPENSION 5 ML is a medication primarily used to manage intraocular pressure in conditions like glaucoma or ocular hypertension. Its effectiveness stems from the synergistic action of its two active ingredients: brimonidine and timolol.
• Brimonidine, an alpha-2 adrenergic receptor agonist, works by reducing the production of aqueous humor, the fluid inside the eye. It achieves this by activating alpha-2 receptors in the ciliary body, the structure responsible for aqueous humor secretion. Activation of these receptors inhibits the enzyme adenylate cyclase, which is involved in aqueous humor production. Additionally, brimonidine enhances the outflow of aqueous humor through the uveoscleral pathway, further reducing intraocular pressure. Essentially, brimonidine lowers the amount of fluid being produced in the eye and increases the rate at which it drains, leading to a decrease in pressure.
• Timolol, on the other hand, is a non-selective beta-adrenergic receptor blocker. It primarily reduces intraocular pressure by decreasing aqueous humor production. Timolol acts on the ciliary epithelium, blocking beta-adrenergic receptors. This blockage reduces the activity of adenylate cyclase, which in turn lowers the production of aqueous humor. Unlike brimonidine, timolol does not significantly affect the outflow of aqueous humor; its main mechanism is to reduce the inflow. By blocking beta receptors, timolol effectively slows down the rate at which the eye produces fluid, thereby lowering the pressure.
• The combination of brimonidine and timolol provides a dual mechanism for controlling intraocular pressure. Brimonidine decreases aqueous humor production and increases outflow, while timolol primarily decreases aqueous humor production. This complementary action results in a more effective and sustained reduction in intraocular pressure compared to either medication used alone. The BAK-free (benzalkonium chloride-free) formulation minimizes the risk of ocular surface toxicity and irritation, making it suitable for long-term use, especially in patients with pre-existing ocular surface disease or those who require chronic glaucoma management. By working together, these ingredients help to protect the optic nerve from damage caused by elevated intraocular pressure, thus preserving vision.

Possible side effects of MAXBRIM PF BAK FREE SUSPENSION 5 ML may include: * **Common Side Effects:** * Eye irritation or discomfort * Temporary blurred vision * Stinging or burning sensation in the eye * Dry eyes * Watery eyes * Foreign body sensation * Redness of the eye * Itching of the eye * **Uncommon Side Effects:** * Allergic reactions (rash, itching, swelling) * Eye pain * Eyelid swelling * Changes in vision * Sensitivity to light * Headache * Dizziness **Note:** This is not an exhaustive list. If you experience any unusual or severe side effects, stop using the medication and consult your doctor immediately.

• If you miss a dose of MAXBRIM PF BAK FREE SUSPENSION 5 ML, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep MAXBRIM PF (BAK FREE) SUSPENSION 5ML away from the reach of children and pets.
• Store MAXBRIM PF (BAK FREE) SUSPENSION 5ML at room temperature.

• **Wash Your Hands:** Always wash your hands thoroughly before using MAXBRIM PF BAK FREE SUSPENSION 5 ML to prevent contamination and infection. Clean hands ensure you're not introducing harmful bacteria into your eyes.
• **Proper Instillation Technique:** Tilt your head back slightly and gently pull down your lower eyelid to create a small pocket. Hold the dropper above your eye and squeeze out the prescribed number of drops. Avoid touching your eye or eyelashes with the dropper tip to maintain sterility.
• **Avoid Contact Lenses:** If you wear contact lenses, remove them before using MAXBRIM PF BAK FREE SUSPENSION 5 ML. Wait at least 15 minutes after applying the drops before reinserting your lenses, unless otherwise directed by your doctor. This prevents interaction between the medication and your lenses.
• **Close Eye Gently:** After instilling the drops, close your eye gently for 1-2 minutes. Avoid blinking excessively or rubbing your eyes, as this can reduce the effectiveness of the medication. Gentle closure allows the medication to be absorbed properly.
• **Storage Instructions:** Store MAXBRIM PF BAK FREE SUSPENSION 5 ML at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not use the medication if it changes color or contains particles. Proper storage ensures the medication remains effective and safe.

• While using MAXBRIM PF BAK FREE SUSPENSION 5 ML, there are no known significant interactions with food. You can use this medicine without regard to food intake. However, it is always recommended to follow your doctor's advice regarding the use of this medicine.