MEGASCAB PLUS LOTION 50 ML

How MEGASCAB PLUS LOTION 50 ML Works

• MEGASCAB PLUS LOTION 50 ML is a comprehensive formulation designed to combat scabies and lice infestations effectively. Its mechanism of action involves a multi-pronged approach, targeting the parasites at different stages of their life cycle. The lotion contains two key active ingredients: Permethrin and Ivermectin, which work synergistically to eradicate the infestation and provide relief from associated symptoms.
• Permethrin, a synthetic pyrethroid, acts as a neurotoxin to the scabies mites and lice. Upon application, Permethrin is absorbed into the parasite's nervous system, disrupting the sodium channels responsible for nerve signal transmission. This disruption leads to paralysis and eventual death of the mites and lice. Permethrin's effect is primarily targeted at the adult parasites, effectively eliminating the active infestation.
• Ivermectin, an antiparasitic agent, complements Permethrin's action by targeting the parasites through a different mechanism. Ivermectin binds to glutamate-gated chloride ion channels in the nerve and muscle cells of the parasites. This binding increases the permeability of the cell membrane to chloride ions, leading to hyperpolarization of the nerve and muscle cells. Hyperpolarization results in paralysis and death of the parasites. Ivermectin is effective against both adult parasites and their larvae, providing a more comprehensive treatment.
• The combined action of Permethrin and Ivermectin ensures a high success rate in eliminating scabies and lice infestations. The lotion's formulation allows for topical application, delivering the active ingredients directly to the affected areas. This localized delivery minimizes systemic absorption and reduces the risk of adverse effects. Moreover, the lotion base helps to soothe the skin, alleviating itching and inflammation associated with the infestation.
• In summary, MEGASCAB PLUS LOTION 50 ML works by paralyzing and killing scabies mites and lice through the neurotoxic effects of Permethrin and Ivermectin. Permethrin disrupts nerve signal transmission by affecting sodium channels, while Ivermectin increases cell membrane permeability to chloride ions, leading to hyperpolarization. This dual-action approach ensures comprehensive eradication of the infestation, providing effective relief from symptoms and preventing recurrence when used as directed.

Like all medicines, MEGASCAB PLUS LOTION 50 ML can cause side effects, although not everybody gets them. **Common Side Effects:** * Itching * Mild burning sensation * Dry skin * Redness or rash **Uncommon Side Effects:** * More severe skin irritation * Swelling * Blisters * Hives **Rare Side Effects:** * Allergic reactions (difficulty breathing, swelling of the face, lips, tongue, or throat) * Numbness or tingling **Important Considerations:** * If any of these side effects become severe or persistent, stop using MEGASCAB PLUS LOTION 50 ML and consult your doctor or pharmacist immediately. * This is not a complete list of all possible side effects. If you notice any other unusual effects, contact your doctor or pharmacist.

• If you forget to apply MEGASCAB PLUS LOTION, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed one and continue with your regular schedule. Do not double the application to make up for a missed dose.

• Keep MEGASCAB PLUS LOTION 50ML away from the reach of children and pets.
• Store MEGASCAB PLUS LOTION 50ML at room temperature.

• **Wash and Dry:** Before applying MEGASCAB PLUS LOTION, ensure the affected skin areas are thoroughly washed with soap and water and then patted dry. This helps the lotion absorb effectively.
• **Apply Thinly:** Apply a thin layer of MEGASCAB PLUS LOTION to all affected areas, not just the spots where you see visible symptoms. Scabies mites can burrow under seemingly unaffected skin. For head lice, ensure the lotion covers the entire scalp and hair, from root to tip.
• **Leave-on Time:** For scabies, leave the lotion on for the duration specified by your doctor, typically 8-12 hours. For head lice, the duration might be shorter, so follow the instructions closely. Setting a timer can help you remember when to wash it off.
• **Wash Off Thoroughly:** After the recommended time, wash off the lotion completely with soap and water. Use a gentle shampoo for hair to ensure no residue remains. Rinse thoroughly to prevent skin irritation.
• **Treat All Family Members:** Scabies and head lice are highly contagious. If one family member is infected, treat all close contacts simultaneously to prevent re-infestation, even if they don't show symptoms. Consult a doctor before treating infants or pregnant women.
• **Clean Bedding and Clothing:** Wash all bedding, clothing, and towels used within the last three days in hot water and dry them on high heat. Items that cannot be washed should be dry-cleaned or sealed in a plastic bag for at least 72 hours to kill any mites or lice.
• **Avoid Re-infestation:** After treatment, avoid close contact with infested individuals and environments. Regularly check for any signs of re-infestation and consult a doctor if symptoms return.
• **Moisturize:** MEGASCAB PLUS LOTION can sometimes cause dryness. Use a gentle, fragrance-free moisturizer after washing off the lotion to soothe and hydrate the skin.
• **Consult a Doctor:** If symptoms persist or worsen after treatment, consult a doctor. They may recommend a different treatment or investigate other potential causes of your skin condition.
• **Proper Disposal:** Dispose of the MEGASCAB PLUS LOTION container properly, following local regulations. Keep out of reach of children.

• There are no known food interactions with MEGASCAB PLUS LOTION 50 ML. It is a topical medication, and its absorption into the bloodstream is minimal. Therefore, it is unlikely to be affected by the food you consume. However, if you experience any unusual side effects, consult your doctor.