MERINETHOL 50MG TABLET 10'S
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MERINETHOL 50MG TABLET 10'S
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MERINETHOL 50MG TABLET 10'S

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MERINETHOL 50MG TABLET 10'S

By RMPL PHARMA LLP

MRP

75

₹57

24 % OFF

₹5.7 Only /

Tablet

10

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Product DetailsArrow

About MERINETHOL 50MG TABLET 10'S

  • MERINETHOL 50MG TABLET 10'S is an anti-cancer medication classified as a purine antagonist, with Mercaptopurine as its active ingredient. It is primarily used in the treatment of acute lymphoblastic leukemia (ALL). ALL is a cancer of the blood and bone marrow, characterized by an overproduction of immature, dysfunctional white blood cells (lymphoblasts) that accumulate in these areas.
  • Before receiving any vaccinations, consult your doctor or nurse. While taking this medication, avoid live vaccines (such as polio, measles, mumps, and rubella) unless your doctor deems it safe. Some vaccines may cause infection during treatment with this drug. Yellow fever vaccination should also be avoided due to the risk of serious illness. Your doctor may order blood and urine tests to monitor kidney function and uric acid levels. Uric acid, a natural substance in the body, can increase during treatment. High uric acid levels can harm the kidneys, potentially requiring dose adjustments. Lower initial doses may be advisable for patients with impaired kidney function due to slower drug elimination and cumulative effects. Dosage reduction should also be considered for patients with impaired liver function.
  • During treatment, your doctor will regularly monitor white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent complications. Inform your doctor about any pre-existing liver disorders, heart failure, high blood cholesterol, or hypertension. This medication can cause liver problems, necessitating weekly liver function tests. Report any hypersensitivity reactions like itchy skin or rashes to your doctor. This tablet contains lactose, which some individuals may have difficulty digesting. If you have lactose intolerance, inform your doctor before starting treatment, as it can cause bloating and abdominal pain. Adhering closely to your doctor's instructions and attending all scheduled appointments will help ensure the safest and most effective treatment possible with MERINETHOL 50MG TABLET 10'S. Regular communication with your healthcare provider about any side effects or concerns is crucial.
  • It's also important to maintain a healthy lifestyle during treatment, including a balanced diet and adequate hydration. Avoid alcohol consumption, as it can further stress the liver. Be vigilant about hygiene to minimize the risk of infections, as this medication can weaken your immune system. Discuss any other medications or supplements you are taking with your doctor to avoid potential drug interactions. Remember that managing ALL is a complex process and MERINETHOL 50MG TABLET 10'S is just one part of the overall treatment plan, which may also include chemotherapy, radiation therapy, or stem cell transplant.

Uses of MERINETHOL 50MG TABLET 10'S

  • Acute lymphoblastic leukemia: This is a type of cancer that affects the blood and bone marrow. In this condition, the bone marrow produces too many immature lymphocytes (a type of white blood cell).

Side Effects of MERINETHOL 50MG TABLET 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Nausea, vomiting
  • Anemia
  • Fever or infection (sore throat, sore mouth, or urinary problems)
  • Unexplained bruising or bleeding
  • Low white blood cell and platelet count

Safety Advice for MERINETHOL 50MG TABLET 10'SArrow

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Pregnancy

UNSAFE

MERINETHOL 50MG TABLET 10'S is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of MERINETHOL 50MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of MERINETHOL 50MG TABLET 10'S based on your specific medical condition, its severity, and other individual health factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medicine. Deviating from the prescribed dosage or schedule can impact the effectiveness of the treatment and potentially lead to adverse effects.
  • For optimal results, take MERINETHOL 50MG TABLET 10'S at the same time each day. This helps maintain a consistent level of the medication in your body. You can take the tablet either with or without food, depending on your preference and how your body responds to it.
  • It is important to swallow the tablet whole with a sufficient amount of water. Do not attempt to chew, crush, or break the tablet, as this may affect the way the medication is absorbed and processed by your body. Altering the tablet's form can change its intended release mechanism.
  • To ensure proper absorption of MERINETHOL 50MG TABLET 10'S, avoid consuming milk or dairy products for at least one hour before and two hours after taking the medication. Dairy products can interfere with the absorption of the active ingredients, potentially reducing the drug's effectiveness. If you have any questions or concerns about dietary restrictions while taking this medication, consult with your doctor or pharmacist.

How to store MERINETHOL 50MG TABLET 10'S?Arrow

  • Keep MERINETHOL 50MG TAB 1X10 away from the reach of children and pets.
  • Store MERINETHOL 50MG TAB 1X10 at room temperature.

Benefits of MERINETHOL 50MG TABLET 10'SArrow

  • MERINETHOL 50MG TABLET 10'S is a chemotherapy medication that disrupts the way cancer cells grow and multiply. It achieves this by interfering with the synthesis of DNA and RNA, the essential building blocks of cells. This interference inhibits nucleotide synthesis, a crucial process for cell replication, effectively slowing down cancer cell growth.
  • Furthermore, MERINETHOL 50MG TABLET 10'S has an immunosuppressive effect, meaning it can weaken the body's immune system. While this might seem counterintuitive, it can be beneficial in certain cancers where the immune system is overactive or contributes to the disease's progression. It also activates enzymes that are capable of directly killing cancer cells, contributing to its overall anti-cancer activity.
  • Often, MERINETHOL 50MG TABLET 10'S is administered in conjunction with other chemotherapy drugs. This combination therapy approach is designed to enhance the overall effectiveness of the treatment, targeting cancer cells through multiple mechanisms and increasing the chances of successful remission. The specific combination of drugs and the dosage will be determined by your doctor based on your individual condition and treatment plan.

How to use MERINETHOL 50MG TABLET 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with MERINETHOL 50MG TABLET 10'S, taking into account your specific medical condition, overall health, and other relevant factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • For optimal results, take MERINETHOL 50MG TABLET 10'S exactly as prescribed by your healthcare provider. Consistency is key; try to take the tablet at the same time each day. This helps maintain a steady level of the medication in your body, maximizing its effectiveness.
  • You can take MERINETHOL 50MG TABLET 10'S either with or without food, depending on your preference and how your stomach tolerates it. However, it's essential to swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet, as this could affect how the medication is absorbed.
  • To ensure proper absorption of the medication, it's important to take MERINETHOL 50MG TABLET 10'S at least one hour before or two hours after consuming milk or other dairy products. The calcium in dairy can interfere with the absorption of the medication, reducing its effectiveness. If you have any concerns about dietary interactions, consult your doctor or pharmacist.

FAQs

What happens if you take MERINETHOL 50MG TABLET 10'S with milk?Arrow

Taking MERINETHOL 50MG TABLET 10'S with milk may decrease the absorption and effectiveness of the medication. This is because the calcium in milk can bind to mercaptopurine, forming an insoluble complex that reduces the amount of the drug that can be absorbed by the body.

Can I drink alcohol while taking MERINETHOL 50MG TABLET 10'S?Arrow

It is generally advised to avoid drinking alcohol while taking MERINETHOL 50MG TABLET 10'S, as alcohol can increase the risk of liver damage.

What is the complication of MERINETHOL 50MG TABLET 10'S?Arrow

MERINETHOL 50MG TABLET 10'S can also cause more serious complications, such as bone marrow suppression, which can lead to decreased production of blood cells and an increased risk of infections, bleeding, and anaemia.

Which enzyme is responsible for metabolism of MERINETHOL 50MG TABLET 10'S?Arrow

The metabolism of MERINETHOL 50MG TABLET 10'S involves several enzymes, including thiopurine S-methyltransferase (TPMT), and xanthine oxidase (XO). Among these enzymes, TPMT is primarily responsible for the metabolism of mercaptopurine. TPMT converts mercaptopurine into 6-methylmercaptopurine, which is then further metabolised into inactive compounds that are excreted from the body.

What is the recommended dose of this drug?Arrow

For the treatment of acute lymphoblastic leukaemia (ALL), the recommended dose for adults and children is approximately 1.5 to 2.5 milligrams per kilogram of body weight taken orally once a day, usually in combination with other chemotherapy medications.

What you should know while taking MERINETHOL 50MG TABLET 10'S?Arrow

You should have caution while taking this MERINETHOL 50MG TABLET 10'S, it can cause liver problems like jaundice, hepatomegaly and anorexia.

What is the interaction of MERINETHOL 50MG TABLET 10'S with other drugs?Arrow

There is NULL interaction of MERINETHOL 50MG TABLET 10'S with other drugs

What advice should I follow while taking MERINETHOL 50MG TABLET 10'S?Arrow

It is advised to consult the physician if you experience fever, sore throat, jaundice, nausea, vomiting, signs of local infection, bleeding from any site, or symptoms suggestive of anaemia. Women of childbearing potential should be advised to avoid becoming pregnant. It is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. This medicine passes into the breast milk. Hence, it is not recommended to breastfeed during this treatment. It is recommended to limit your alcohol intake or avoid it altogether during the treatment. While you are taking this drug, you are more sensitive to the sun and UV light. Just make sure to limit your exposure to sunlight and UV light, wear protective clothing and use a sun cream with a high sun protection factor (SPF). Low blood sugar (sweating more than usual, nausea, dizziness, confusion, etc.) has sometimes been seen in children, mainly in children under the age of six or with a low body mass index. Talk to your child's doctor if this happens.

What is MERINETHOL 50MG TABLET 10'S made of?Arrow

MERINETHOL 50MG TABLET 10'S is made of MERCAPTOPURINE molecule/combination.

For what diseases MERINETHOL 50MG TABLET 10'S is used?Arrow

MERINETHOL 50MG TABLET 10'S is used for treating diseases like Oncology and Gastroenterology.

References

Book Icon

Aspen Pharma Trading Limited, Electronic medicines compendium (emc)

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Purinethol® (mercaptopurine) 50-mg scored tablets caution. Available at:

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Mercaptopurine - HPRA. Available at:

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Marketer / Manufacturer Details

RMPL PHARMA LLP

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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