MEROFIC SB 1.5GM INJECTION
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MEROFIC SB 1.5GM INJECTION
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MEROFIC SB 1.5GM INJECTION

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MEROFIC SB 1.5GM INJECTION

By GUFIC BIOSCIENCE LIMITED

MRP

1499

₹1499

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Product DetailsArrow

About MEROFIC SB 1.5GM INJECTION

  • MEROFIC SB 1.5GM INJECTION is a potent antibiotic combination designed to combat a wide range of bacterial infections. It contains Meropenem, a broad-spectrum carbapenem antibiotic, and Sulbactam, a beta-lactamase inhibitor. This combination ensures enhanced efficacy against bacteria that have developed resistance to other antibiotics.
  • Meropenem works by inhibiting the synthesis of the bacterial cell wall, leading to bacterial cell death. Sulbactam enhances Meropenem's activity by preventing the breakdown of Meropenem by beta-lactamase enzymes produced by resistant bacteria. By inactivating these enzymes, Sulbactam helps Meropenem reach its target and effectively kill the bacteria.
  • This injection is typically administered intravenously or intramuscularly by a healthcare professional. It is used to treat severe infections such as pneumonia, bloodstream infections, intra-abdominal infections, and skin and soft tissue infections. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's overall health condition.
  • MEROFIC SB 1.5GM INJECTION offers a powerful solution for combating complex bacterial infections, especially those resistant to other commonly used antibiotics. It is crucial to use this medication under the guidance of a healthcare professional to ensure appropriate dosage and minimize the risk of side effects. Common side effects may include nausea, vomiting, diarrhea, and injection site reactions. In rare cases, more serious side effects such as seizures or allergic reactions may occur.

Uses of MEROFIC SB 1.5GM INJECTION

  • Pneumonia (Lung Infection)
  • Skin and Soft Tissue Infections
  • Intra-abdominal Infections
  • Meningitis (Infection of the brain and spinal cord)
  • Septicemia (Blood Infection)
  • Prevention of Surgical Site Infections
  • Urinary Tract Infections (UTIs)
  • Gynecological Infections
  • Infections in Neutropenic Patients (Infections in patients with low white blood cell count)
  • Respiratory Tract Infections

How MEROFIC SB 1.5GM INJECTION Works

  • MEROFIC SB 1.5GM INJECTION is a powerful combination medication containing Meropenem and Sulbactam, designed to combat a wide range of bacterial infections. Meropenem belongs to a class of antibiotics known as carbapenems, while Sulbactam is a beta-lactamase inhibitor. Understanding how each component works is crucial to appreciating the overall effectiveness of this injection.
  • Meropenem works by interfering with the bacteria's ability to build their cell walls. Bacterial cell walls are essential for protecting the bacteria and maintaining their structure. Meropenem inhibits the synthesis of peptidoglycans, which are crucial components of these cell walls. By blocking peptidoglycan synthesis, Meropenem weakens the cell wall, eventually causing the bacterial cell to break open and die. This action makes Meropenem highly effective against many gram-positive and gram-negative bacteria, including those resistant to other antibiotics.
  • However, some bacteria produce enzymes called beta-lactamases, which can break down and inactivate Meropenem. This is where Sulbactam plays a vital role. Sulbactam is a beta-lactamase inhibitor, meaning it binds to beta-lactamase enzymes and prevents them from breaking down Meropenem. By inhibiting beta-lactamase, Sulbactam ensures that Meropenem can reach its target – the bacterial cell wall – without being deactivated. This synergistic effect broadens the spectrum of bacteria that MEROFIC SB 1.5GM INJECTION can effectively target, including bacteria that are resistant to Meropenem alone.
  • In essence, MEROFIC SB 1.5GM INJECTION provides a two-pronged attack on bacterial infections. Meropenem directly kills bacteria by disrupting cell wall synthesis, while Sulbactam protects Meropenem from being broken down by bacterial enzymes. This combination makes MEROFIC SB 1.5GM INJECTION a valuable tool in treating severe and complicated infections, especially those involving resistant bacteria. The coordinated action ensures a higher concentration of active Meropenem at the infection site, leading to more effective bacterial eradication and improved patient outcomes.

Side Effects of MEROFIC SB 1.5GM INJECTIONArrow

Like all medicines, MEROFIC SB 1.5GM INJECTION can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Injection site reactions, including pain, swelling, and inflammation * Headache * Nausea * Vomiting * Diarrhea * Rash * Itching * Increased liver enzymes in the blood * Thrombophlebitis (blood clot in a vein) **Uncommon Side Effects (may affect up to 1 in 100 people):** * Oral thrush (fungal infection in the mouth) * Vaginal thrush * Abdominal pain * Constipation * Changes in blood cell counts (including decreased white blood cells, platelets, and red blood cells) * Hypokalemia (low potassium levels in the blood) * Anxiety * Confusion * Dizziness * Seizures (fits) * Stevens-Johnson Syndrome (a severe skin reaction) * Toxic epidermal necrolysis (another severe skin reaction) * Kidney problems * Liver problems **Rare Side Effects (may affect up to 1 in 1,000 people):** * Pseudomembranous colitis (inflammation of the colon) * Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Hemolytic anemia (destruction of red blood cells) **Not Known (frequency cannot be estimated from the available data):** * Allergic reactions, which may be severe and include difficulty breathing, wheezing, swelling of the face, lips, tongue or throat, and skin rash. **Important Information:** This is not a complete list of all possible side effects. If you experience any unusual symptoms while taking MEROFIC SB 1.5GM INJECTION, talk to your doctor or pharmacist.

Safety Advice for MEROFIC SB 1.5GM INJECTIONArrow

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Allergies

Unsafe

Do not use if you are allergic to Merofic SB 1.5GM Injection or any of its ingredients.

Dosage of MEROFIC SB 1.5GM INJECTIONArrow

  • The dosage of MEROFIC SB 1.5GM INJECTION is determined by several factors, including the severity and type of infection, the patient's age, weight, kidney function, and overall health condition. It is crucial to adhere strictly to the prescribed dosage and administration schedule provided by your healthcare provider. Self-adjusting the dosage or discontinuing the medication prematurely can lead to antibiotic resistance or incomplete treatment of the infection.
  • For adults with normal kidney function, the typical dosage of MEROFIC SB 1.5GM INJECTION ranges from 500 mg to 2 grams administered intravenously every 8 hours. In cases of severe infections, such as pneumonia, intra-abdominal infections, or bloodstream infections, the higher end of the dosage range may be necessary. Patients with impaired kidney function may require dosage adjustments to prevent drug accumulation and potential side effects. Your doctor will carefully assess your kidney function and adjust the dosage accordingly.
  • In pediatric patients, the dosage of MEROFIC SB 1.5GM INJECTION is calculated based on body weight. The usual dosage ranges from 10 to 20 mg per kilogram of body weight, administered intravenously every 8 hours. As with adults, dosage adjustments may be necessary for children with kidney problems. The duration of treatment with MEROFIC SB 1.5GM INJECTION varies depending on the type and severity of the infection, but it typically lasts for 7 to 14 days. It is essential to complete the full course of treatment, even if you start feeling better before the end of the prescribed period.
  • MEROFIC SB 1.5GM INJECTION is administered intravenously, usually over a period of 15 to 30 minutes. The injection should be prepared and administered by a qualified healthcare professional. It is important to monitor patients for any signs of adverse reactions during and after the infusion. Take 'MEROFIC SB 1.5GM INJECTION' only as per the prescription by your physician only.

What if I miss my dose of MEROFIC SB 1.5GM INJECTION?Arrow

  • If you miss a dose of MEROFIC SB 1.5GM INJECTION, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store MEROFIC SB 1.5GM INJECTION?Arrow

  • Keep MEROFIC SB 1000/500MG INJ away from the reach of children and pets.
  • Store MEROFIC SB 1000/500MG INJ at room temperature.

Benefits of MEROFIC SB 1.5GM INJECTIONArrow

  • MEROFIC SB 1.5GM INJECTION is a powerful antibiotic combination, meticulously formulated to combat a wide spectrum of bacterial infections. Its dual-action mechanism, combining Meropenem and Sulbactam, ensures robust efficacy against resistant bacteria, offering a significant advantage in treating severe and life-threatening conditions. Meropenem, a broad-spectrum carbapenem antibiotic, effectively destroys bacteria by interfering with their cell wall synthesis. Sulbactam, a beta-lactamase inhibitor, enhances Meropenem's activity by preventing the breakdown of the antibiotic by bacterial enzymes, thus broadening its spectrum of action.
  • This injection is particularly valuable in treating complicated intra-abdominal infections, such as peritonitis and abscesses, where multiple types of bacteria, including resistant strains, may be present. It is also highly effective against severe pneumonia, including hospital-acquired pneumonia and ventilator-associated pneumonia, offering a critical treatment option for patients in intensive care units. Furthermore, MEROFIC SB 1.5GM INJECTION is a crucial treatment for complicated urinary tract infections (cUTIs), including pyelonephritis, especially when caused by multidrug-resistant bacteria. Its broad-spectrum activity ensures comprehensive coverage against common and uncommon urinary pathogens.
  • MEROFIC SB 1.5GM INJECTION demonstrates notable efficacy in treating skin and soft tissue infections, including cellulitis, necrotizing fasciitis, and diabetic foot infections. These infections often involve a mix of aerobic and anaerobic bacteria, and the combination of Meropenem and Sulbactam provides a synergistic effect, leading to improved clinical outcomes. Additionally, it serves as a vital therapeutic option for bloodstream infections (bacteremia) and sepsis, particularly when caused by Gram-negative bacteria. Its rapid bactericidal action helps control the infection quickly, reducing the risk of septic shock and organ failure.
  • Another significant benefit of MEROFIC SB 1.5GM INJECTION lies in its ability to treat infections in immunocompromised patients, such as those undergoing chemotherapy or organ transplantation. These patients are highly susceptible to opportunistic infections, and this injection provides a reliable defense against a wide range of bacterial pathogens. Moreover, it can be used as an empirical therapy in patients with suspected bacterial infections when the causative organism is unknown, allowing for timely and effective treatment initiation. The combination of Meropenem and Sulbactam minimizes the risk of resistance development compared to single-agent antibiotics, contributing to its long-term effectiveness. It is often reserved for serious infections or when other antibiotics have failed, making it a critical tool in combating antibiotic resistance.
  • MEROFIC SB 1.5GM INJECTION's use is generally reserved for more severe infections, or those where other antibiotics are not suitable due to resistance or patient factors. This targeted approach helps to preserve the effectiveness of other antibiotics and slow the spread of resistance. Finally, because MEROFIC SB 1.5GM INJECTION is administered intravenously, it ensures that the medication is delivered directly into the bloodstream, bypassing the digestive system and achieving high concentrations at the site of infection. This can be particularly important in patients who are unable to take oral medications or who have gastrointestinal issues that may impair absorption.

How to use MEROFIC SB 1.5GM INJECTIONArrow

  • MEROFIC SB 1.5GM INJECTION is typically administered by a healthcare professional in a hospital or clinical setting. It is crucial to follow their instructions carefully regarding dosage and administration schedule. This medication is usually given intravenously (IV) or intramuscularly (IM).
  • For IV administration, the MEROFIC SB 1.5GM INJECTION solution is prepared by reconstituting the powder with a compatible intravenous fluid, such as sterile water for injection or sodium chloride solution. The healthcare provider will determine the appropriate volume of diluent based on the patient's needs and the desired concentration. The reconstituted solution is then slowly injected into a vein over a period of 15 to 30 minutes.
  • For IM administration, the injection is given directly into a large muscle, such as the gluteus maximus (buttocks) or thigh. The healthcare provider will select the appropriate injection site and use proper technique to ensure the medication is delivered effectively.
  • The dosage of MEROFIC SB 1.5GM INJECTION varies depending on the severity and type of infection, the patient's age, weight, and kidney function. It is essential to complete the full course of treatment as prescribed by the doctor, even if you start feeling better before the medication is finished. Stopping the medication prematurely can lead to the infection recurring or becoming resistant to antibiotics.
  • During treatment with MEROFIC SB 1.5GM INJECTION, it is important to stay well-hydrated by drinking plenty of fluids. Monitor for any signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing, and report them to your healthcare provider immediately. Also, inform your doctor about any other medications you are taking, as drug interactions can occur. Regular blood tests may be required to monitor kidney function and other parameters while on this medication.
  • Always adhere to the healthcare provider's instructions and ask any questions you may have regarding the administration or potential side effects of MEROFIC SB 1.5GM INJECTION. Self-administration is strongly discouraged.

Quick Tips for MEROFIC SB 1.5GM INJECTIONArrow

  • Complete the Full Course: Even if you start feeling better, finish the entire course of MEROFIC SB 1.5GM INJECTION as prescribed by your doctor. Stopping early can lead to the infection returning and becoming harder to treat because the bacteria may develop resistance to the antibiotic.
  • Maintain Good Hydration: Drink plenty of fluids while you're on MEROFIC SB 1.5GM INJECTION. Staying hydrated helps your body flush out the infection and can also minimize potential side effects like nausea. Aim for at least 8-10 glasses of water a day, unless your doctor advises otherwise.
  • Report Any Side Effects Promptly: MEROFIC SB 1.5GM INJECTION is a powerful antibiotic, and while generally safe, it can cause side effects. Tell your doctor immediately if you experience severe diarrhea, stomach cramps, skin rash, itching, swelling, or difficulty breathing. Don't wait; prompt reporting helps manage side effects effectively.
  • Inform Your Doctor About All Medications: Before starting MEROFIC SB 1.5GM INJECTION, make sure your doctor knows about all other medications you're taking, including over-the-counter drugs, herbal remedies, and supplements. This helps avoid potential drug interactions that could reduce the effectiveness of the injection or increase the risk of side effects.
  • Follow Storage Instructions Carefully: MEROFIC SB 1.5GM INJECTION is usually administered in a hospital setting, but if you are receiving it at home, adhere strictly to the storage guidelines provided by your healthcare professional. Improper storage can compromise the drug's potency and effectiveness. Always use as directed.

Food Interactions with MEROFIC SB 1.5GM INJECTIONArrow

  • There are no known significant food interactions with MEROFLC SB 1.5GM INJECTION. It can be administered without regard to food.

FAQs

What is MEROFIC SB 1.5GM INJECTION?Arrow

MEROFIC SB 1.5GM INJECTION is an antibiotic used to treat a variety of bacterial infections. It contains a combination of Meropenem and Sulbactam.

What are the uses of MEROFIC SB 1.5GM INJECTION?Arrow

MEROFIC SB 1.5GM INJECTION is used to treat bacterial infections such as pneumonia, meningitis, abdominal infections, urinary tract infections, and skin and soft tissue infections.

How is MEROFIC SB 1.5GM INJECTION administered?Arrow

MEROFIC SB 1.5GM INJECTION is usually administered by a healthcare professional as an injection into a vein. Do not administer it yourself.

What are the common side effects of MEROFIC SB 1.5GM INJECTION?Arrow

Common side effects of MEROFIC SB 1.5GM INJECTION include nausea, vomiting, diarrhea, pain or swelling at the injection site, and headache.

Is MEROFIC SB 1.5GM INJECTION safe during pregnancy?Arrow

There is limited information available regarding the safety of MEROFIC SB 1.5GM INJECTION during pregnancy. It should only be used if the potential benefit justifies the risk.

Is MEROFIC SB 1.5GM INJECTION safe during breastfeeding?Arrow

It is not known whether MEROFIC SB 1.5GM INJECTION is excreted in breast milk. Consult your doctor before breastfeeding.

Can MEROFIC SB 1.5GM INJECTION interact with other medications?Arrow

MEROFIC SB 1.5GM INJECTION can interact with certain medications, such as probenecid and valproic acid. Inform your doctor about all the medications you are taking.

What is the dosage of MEROFIC SB 1.5GM INJECTION?Arrow

The dosage of MEROFIC SB 1.5GM INJECTION varies depending on the severity of the infection and the patient's condition. Your doctor will determine the appropriate dosage.

How to store MEROFIC SB 1.5GM INJECTION?Arrow

Store MEROFIC SB 1.5GM INJECTION at room temperature, away from light and moisture. Keep it out of reach of children and pets.

Are there other brands of Meropenem and Sulbactam available?Arrow

Yes, there are other brands of Meropenem and Sulbactam available in the market. Consult your pharmacist or doctor for more information.

What happens if I miss a dose of MEROFIC SB 1.5GM INJECTION?Arrow

If you miss a dose of MEROFIC SB 1.5GM INJECTION, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can MEROFIC SB 1.5GM INJECTION cause allergic reactions?Arrow

Yes, MEROFIC SB 1.5GM INJECTION can cause allergic reactions in some people. Seek immediate medical attention if you experience any allergic reaction.

What are the symptoms of an overdose of MEROFIC SB 1.5GM INJECTION?Arrow

Symptoms of an overdose of MEROFIC SB 1.5GM INJECTION may include seizures, confusion, and coma. Seek immediate medical attention if you think you have taken too much of the medicine.

Can MEROFIC SB 1.5GM INJECTION cause antibiotic resistance?Arrow

Yes, overuse of antibiotics can lead to antibiotic resistance. Use MEROFIC SB 1.5GM INJECTION only when prescribed by your doctor.

What is the price of MEROFIC SB 1.5GM INJECTION?Arrow

The price of MEROFIC SB 1.5GM INJECTION may vary depending on the pharmacy and location.

References

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DrugBank: Meropenem

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FDA Label: Meropenem for Injection

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European Medicines Agency (EMA): Meronem (Meropenem) EPAR

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NIH - StatPearls: Meropenem

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PubChem: Meropenem

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Ratings & Review

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

Reviewed on 05-12-2022

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(3/5)

Good for generic medicine, quality medicine with affordable rate

nitesh vekariya

Reviewed on 03-02-2024

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(5/5)

You can easily get, Medicines at half the price

Shourya Kharbanda

Reviewed on 30-01-2024

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(5/5)

Best and cheapest medicine.

Shubham Jain

Reviewed on 23-11-2022

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(5/5)

Good place to buy generic medicines

Patel Jinal

Reviewed on 24-05-2023

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(5/5)


Marketer / Manufacturer Details

GUFIC BIOSCIENCE LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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