MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S
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MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S
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MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

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MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

By ZYDUS LIFESCIENCES LIMITED

MRP

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27995

₹22396

20 % OFF

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10

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Product DetailsArrow

About MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

  • MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S contains the active substance midostaurin. It is an anti-cancer medicine that belongs to the class of medications called tyrosine kinase inhibitors. It is combined with other chemotherapy medications to treat acute myeloid leukemia (AML) in adults with a defect in a gene called FLT3. Acute myeloid leukemia is a form of cancer that starts in certain WBC called myeloid cells in which the body overproduces these cells abnormally. The medicine is also used in adults to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).
  • Do not take MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S if you are allergic to Midostaurin or any other ingredients of this medicine. Before commencing treatment with this medication, proactively inform your healthcare provider about any pre-existing health conditions, including but not limited to infections, heart disorders, lung problems, or breathing difficulties. It is crucial to promptly report any emergent symptoms experienced post-medication intake, such as fever, sore throat, mouth ulcers, persistent cough (with or without mucus production), chest pain, dyspnea, or unusual swelling in any body part, to your attending physician for immediate evaluation and management.
  • MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is not recommended for use in pediatric patients, specifically children and adolescents under the age of 18 years. If you are pregnant, breastfeeding, or actively trying to conceive, it is imperative to discuss these circumstances with your physician before initiating treatment with this medication. Please be aware that MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S has the potential to reduce fertility in both men and women. Therefore, a thorough discussion with your healthcare provider regarding these potential effects is strongly advised before starting therapy. The most commonly reported side effects associated with this medicine include fever accompanied by reduced blood cell counts, nausea, vomiting, headache, musculoskeletal pain, elevated blood glucose levels, and respiratory tract infections. Regular monitoring and management of these side effects are essential throughout the treatment course.

Uses of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

  • Acute myeloid leukemia (AML) is a rapidly progressing cancer of the blood and bone marrow. It's characterized by the overproduction of immature white blood cells, hindering the development of normal blood cells.
  • Aggressive systemic mastocytosis (ASM) is a rare and severe form of mastocytosis. It involves the accumulation of mast cells in various organs, leading to organ damage and dysfunction.
  • Systemic mastocytosis with associated hematological neoplasm (SM-AHN) is a condition where systemic mastocytosis occurs alongside another blood cancer. This combination presents unique challenges for diagnosis and treatment.
  • Mast cell leukemia (MCL) is a very rare and aggressive form of leukemia. It's characterized by a significant increase in mast cells in the blood and bone marrow, leading to organ damage and a poor prognosis.

Side Effects of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Here is a list of possible side effects of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S.

  • Swelling in the lower limbs
  • Skin rash
  • Increased blood sugar levels
  • Abdominal pain
  • Constipation, diarrhea
  • Nausea, vomiting
  • Musculoskeletal pain
  • Headache
  • Bleeding from nose
  • Upper respiratory infection
  • Tiredness
  • Fever
  • Heart failure
  • GI bleeding
  • Fever with decreased blood cell counts
  • Hypersensitivity reactions
  • Kidney problems
  • Pneumonia
  • Blood infection

Safety Advice for MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'SArrow

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Pregnancy

UNSAFE

MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using effective contraception during the treatment and for at least 4 months after your last dose is necessary.

Dosage of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to adhere to your doctor's instructions precisely.
  • Administer MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S exactly as prescribed by your healthcare provider. To ensure proper absorption and minimize potential side effects, consistently take it at the same time each day, without fail.
  • Do not attempt to alter the capsule in any way before consumption. Avoid opening, breaking, crushing, or chewing the capsules. The capsule should be swallowed whole with a full glass of water to facilitate its passage into the stomach.
  • Taking MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S with food is essential. This helps to optimize the absorption of the medication and reduce the likelihood of gastrointestinal discomfort. Follow this instruction diligently to enhance the effectiveness of the treatment.

How to store MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S?Arrow

  • Keep MIDOSTAR 25MG CAP 1X28 away from the reach of children and pets.
  • Store MIDOSTAR 25MG CAP 1X28 at room temperature.

Benefits of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'SArrow

  • MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is a targeted therapy medication classified as a kinase inhibitor. It works by selectively blocking the activity of specific enzymes called kinases, which are crucial for cell growth and division. In particular, MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S demonstrates a potent inhibitory effect on multiple receptor tyrosine kinases, including FLT3 (Fms-like tyrosine kinase 3).
  • FLT3 mutations are commonly found in certain types of blood cancers, such as acute myeloid leukemia (AML). These mutations lead to the overactivation of the FLT3 kinase, driving uncontrolled proliferation and survival of leukemia cells. MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S effectively targets and inhibits the action of these mutated FLT3 kinases, thereby disrupting the signaling pathways that promote cancer cell growth.
  • By blocking the activity of FLT3 and other relevant kinases, MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S helps to slow down or halt the division and growth of abnormal cells expressing FLT3 mutant genes. This mechanism of action makes it a valuable treatment option for patients with AML harboring FLT3 mutations, as it can potentially lead to remission or improved outcomes.

How to use MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It's crucial to adhere to your doctor's instructions meticulously when taking MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S.
  • Administer MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S exactly as prescribed by your healthcare provider. These capsules are designed to be swallowed whole, so avoid opening, breaking, crushing, or chewing them. Doing so could alter the way the medication is absorbed and potentially reduce its effectiveness.
  • To ensure consistent absorption, swallow the capsule whole with a full glass of water. Taking the capsules at the same time each day is highly recommended, as this helps maintain a steady level of the medication in your system. Consistency in timing can significantly contribute to the treatment's success.
  • Furthermore, it is important to take MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S with food. This can help to minimize potential stomach upset and optimize the drug's absorption. If you have any questions or concerns about how to take this medication, or if you experience any unexpected side effects, consult with your doctor or pharmacist for further guidance.

FAQs

What are the cautions of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S?Arrow

Tell your doctor immediately if you start to have swelling of your face, lower limbs or skin, fever, sore throat, mouth ulcers, cough with or without mucous, chest pain or discomfort, trouble breathing, shortness of breath, light-headedness, fainting, dizziness, blue discoloration of your lips, hands or feet.

Can MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S cause vomiting?Arrow

Yes, MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S has a moderate emetic effect and can cause vomiting. Do not take an extra capsule if you have vomited after taking your first dose.

Does MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S cause hair loss?Arrow

No, hair loss is not a side effect of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S. Hair loss can happen due to cancer itself. Consult your doctor if you have excessive hair loss.

How will I be monitored during the treatment with MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S?Arrow

Your doctor will perform regular blood tests during treatment with Rydapt in order to monitor the number of blood cells (white blood cells, red blood cells, and platelets) and electrolytes such as calcium, potassium, and magnesium in your body. Your heart and lung function will also be checked regularly.

How long does it take MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S to work?Arrow

MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

What will happen if I stop taking MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S suddenly?Arrow

Stopping your treatment suddenly may cause your condition to become worse. Do not stop taking your medicine without consulting your doctor.

What are the drug interactions of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S?Arrow

There are no known drug interactions of MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S.

What advice should I follow while taking MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S?Arrow

Do not breastfeed during the treatment with MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S and for at least 4 months after the last dose. Avoid grapefruit juice during the treatment with this medicine. If you vomit after taking this medicine, do not take another capsule to make up the dose. If you are a male patient with a female partner with reproducing potential, use effective contraception during the treatment and for 4 months after the last dose. Your doctor will perform regular blood tests during the treatment to monitor the number of blood cells and electrolytes in your body. Your heart and lung function will also be checked regularly. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

What is MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S made of?Arrow

MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is made of Midostaurin.

What ailments are MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S used to treat?Arrow

MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S is used to treat ailments related to Oncology.

References

Book Icon

Novartis Pharmaceuticals, Electronic Medicines Compendium (EMC), www.medicines.org.uk.

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Novartis Pharmaceuticals, Highlights Of Prescribing Information, Midostaurin.

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Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

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MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

MIDOSTAR 25MG SOFT GELATIN CAPSULE 28'S

MRP

₹

27995

₹22396

20 % OFF

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