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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

General Safety and Monitoring
Use only under medical supervisionMisoprost 200 is a potent medicine that should only be used on prescription and under the supervision of a qualified healthcare professional familiar with its indications, contraindications, and monitoring requirements.
MISOPROST 200MCG TABLET 4'S contains a medicine called Misoprostol. It helps in medical termination of the pregnancy. It is prescribed along with another medicine called Mifepristone. It is only used to terminate a pregnancy which should not be more than 63 days old, counting from the first day of the last menstrual period. It works by increasing the contractions of the uterus. It may also be used in the prevention or treatment of post-delivery bleeding and for cervical ripening.
This medicine is administered only in a clinic or healthcare facility under the supervision of a gynaecologist.
For medical termination of pregnancy: You may experience abdominal cramping, diarrhea, stomach pain, and nausea immediately after taking MISOPROST 200MCG TABLET 4'S. You may also have vaginal bleeding within 4 hours of taking MISOPROST 200MCG TABLET 4'S. You may also be asked to stay at the clinic or healthcare center for at least 3 hours after taking this medicine. After 14 days of taking Mifepristone (pill you took before MISOPROST 200MCG TABLET 4'S) your gynaecologist may run some blood tests or perform ultrasonography to confirm whether pregnancy has been terminated or not.
No, studies have shown that this medicine does not impair the fertility of the women. Your future chances of getting pregnant are as equal as of those who have not taken this medicine.
The common side effects of using MISOPROST 200MCG TABLET 4'S are abdominal pain, abdominal cramping, nausea, diarrhea, dizziness, uterine contractions, pelvic pain, and shivering. If you experience a very heavy vaginal bleeding or if any of these side effects bother you please consult with your gynaecologist.
Misoprost 200 tablet is a prescription medicine that contains misoprostol, a synthetic analogue of prostaglandin E1. It is used for specific gynecological and obstetric indications, such as medical termination of pregnancy in combination with other medicines, cervical ripening, induction or augmentation of labor in selected settings, and management of certain types of pregnancy loss according to local protocols. It is also used for prevention of gastric and duodenal ulcers in high‑risk patients taking NSAIDs. The strength "200" usually refers to 200 micrograms of misoprostol per tablet.
Misoprost 200 works by mimicking the action of natural prostaglandin E1. In the uterus, it increases the frequency and intensity of uterine contractions and softens the cervix, which helps in expelling uterine contents or facilitating labor, depending on the clinical indication and protocol. In the gastrointestinal tract, misoprostol reduces gastric acid secretion and increases mucus and bicarbonate production, thereby protecting the stomach lining from damage, particularly in patients taking NSAIDs. These effects are dose‑ and route‑dependent and must be carefully controlled by a clinician.
Approved uses of misoprostol vary by country, but commonly include prevention of NSAID‑induced gastric and duodenal ulcers in high‑risk adults and, in combination with other medicines, medical termination of intrauterine pregnancy under defined conditions. It is also used for cervical ripening before certain gynecological procedures and, in some settings, for induction of labor or management of early pregnancy loss and postpartum hemorrhage according to institutional protocols. Because indications and legal status differ between regions, patients should rely on local guidelines and a specialist’s prescription rather than assuming a particular use.
No. Misoprost 200 should never be used for self‑managed abortion without medical supervision. Medical termination of pregnancy requires proper assessment of gestational age, confirmation of intrauterine pregnancy, exclusion of ectopic pregnancy, evaluation of anemia and other risk factors, and clear counseling about the procedure and follow‑up. Incorrect dose, route, or timing can lead to incomplete abortion, severe bleeding, infection, or uterine rupture, and may endanger your life. Use of misoprostol for termination of pregnancy is also regulated by law, and must follow national regulations and be supervised by a qualified clinician.
Common side effects of Misoprost 200 include abdominal pain, uterine cramping, diarrhea, nausea, vomiting, chills, and transient fever. Headache and dizziness may also occur. When used for obstetric or gynecologic indications, vaginal bleeding and passage of clots or tissue are expected effects but can sometimes become excessive. Serious but less common adverse effects include heavy or prolonged bleeding, severe abdominal pain, uterine rupture (especially in women with previous cesarean section or uterine surgery), infection, severe allergic reactions, and significant dehydration due to persistent diarrhea or vomiting. Any severe or unexpected symptom requires urgent medical evaluation.
Misoprost 200 is contraindicated in ongoing desired pregnancy because it can cause uterine contractions, miscarriage, or fetal harm. It is used intentionally in controlled settings for medical termination of pregnancy, induction of labor, or management of pregnancy loss, but only under specialist supervision and in accordance with legal and clinical guidelines. If misoprostol is taken inadvertently in early pregnancy, there is a risk of pregnancy loss and potential congenital anomalies in surviving fetuses. Pregnant women should never take Misoprost 200 for ulcer prevention or any non‑obstetric indication. If accidental exposure occurs, immediate consultation with an obstetrician is essential.
Misoprostol is converted to an active metabolite that appears in breast milk in small amounts. Available data suggest that short‑term use is generally compatible with breastfeeding, particularly when used in the immediate postpartum period for obstetric indications. However, infants should be monitored for loose stools or irritability. For prolonged use, such as ulcer prevention, the risk–benefit balance should be carefully assessed by the prescribing clinician. Breastfeeding mothers should always inform their doctor before starting Misoprost 200 so that timing of doses and monitoring of the infant can be planned appropriately.
Yes. Misoprost 200 should be used with caution in patients with cardiovascular disease, hypotension or hypertension, inflammatory bowel disease, dehydration, or conditions where strong uterine contractions may pose a risk, such as previous cesarean section or major uterine surgery, uterine malformations, or multiple pregnancy, depending on the indication. It should also be used carefully in patients with severe liver or kidney impairment, as drug handling may be altered. In all such cases, the decision to use misoprostol, and the dose and route, must be individualized by a specialist, with close monitoring for adverse effects.
Alcohol is not known to have a direct pharmacological interaction with misoprostol, but combining the two is generally discouraged. Alcohol can worsen gastrointestinal irritation, increase the risk of dehydration if vomiting or diarrhea occur, and impair judgment, which is particularly concerning when you need to monitor bleeding, pain, or other symptoms closely. If Misoprost 200 is being used for obstetric or gynecologic purposes, avoiding alcohol is strongly advised so that you can recognize and respond promptly to any complications. Discuss alcohol use with your clinician before starting therapy.
Very heavy bleeding after taking Misoprost 200 is a medical emergency. Seek immediate care if you soak more than two large sanitary pads per hour for two consecutive hours, pass very large clots, feel dizzy, faint, have a racing heartbeat, or experience severe abdominal pain. Do not drive yourself if you feel unwell; arrange for someone to accompany you or call emergency services. Inform the treating team about the exact medicines and doses you have taken, the time of intake, and any previous uterine surgery or medical conditions. Prompt evaluation may include physical examination, blood tests, ultrasound, and interventions to control bleeding.
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CIPLA PHARMACEUTICAL COMPANY LIMITED
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India
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