MYCURIT 3 TABLET 10'S

How MYCURIT 3 TABLET 10'S Works

• MYCURIT 3 TABLET 10'S is a combination medication designed to combat tuberculosis (TB), a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. This tablet contains a synergistic blend of three active ingredients: Isoniazid, Rifampicin, and Pyrazinamide. Each component plays a crucial role in disrupting the growth and spread of TB bacteria within the body.
• Isoniazid, also known as isonicotinylhydrazine (INH), works primarily by inhibiting the synthesis of mycolic acids, essential components of the bacterial cell wall of Mycobacterium tuberculosis. By interfering with mycolic acid production, Isoniazid weakens the cell wall, making the bacteria more vulnerable and preventing their replication. Specifically, Isoniazid targets the enzyme InhA, which is involved in the synthesis of mycolic acids. This action effectively stops the bacteria from multiplying and spreading.
• Rifampicin functions through a different mechanism. It inhibits bacterial DNA-dependent RNA polymerase, an enzyme crucial for bacterial RNA synthesis. By binding to this enzyme, Rifampicin prevents the bacteria from transcribing DNA into RNA, effectively halting protein synthesis and, consequently, bacterial growth. Rifampicin's broad-spectrum activity allows it to target actively growing as well as dormant or semi-dormant TB bacteria, making it a vital component in eradicating the infection.
• Pyrazinamide's mechanism of action is somewhat complex and not fully understood. However, it is believed to disrupt the transport functions across the cell membrane and interfere with the production of mycolic acid. Pyrazinamide is a prodrug, meaning it converts into its active form, pyrazinoic acid (POA), inside the body. This conversion is facilitated by the bacterial enzyme pyrazinamidase. POA lowers the pH inside the TB bacteria, creating an acidic environment that inhibits their growth and survival. Pyrazinamide is particularly effective against TB bacteria that are located within macrophages (immune cells), an environment where other anti-TB drugs may not be as effective.
• The combined action of Isoniazid, Rifampicin, and Pyrazinamide in MYCURIT 3 TABLET 10'S provides a potent and comprehensive approach to treating tuberculosis. By attacking the TB bacteria through multiple pathways, this combination therapy increases the likelihood of successful treatment, reduces the risk of drug resistance, and shortens the overall duration of therapy. It's crucial to follow the prescribed dosage and treatment duration as directed by a healthcare professional to ensure the complete eradication of the infection and prevent the development of drug-resistant strains.

Common side effects of Mycurit 3 Tablet may include nausea, vomiting, stomach pain, loss of appetite, skin rash, itching, and headache. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, pale stools), allergic reactions (such as swelling of the face, lips, tongue, or throat, difficulty breathing), and changes in blood counts. Other reported side effects are fatigue, dizziness, and gastrointestinal disturbances. This is not an exhaustive list, and patients should consult their doctor for a complete list and medical advice if they experience any unusual symptoms.

• If you miss a dose of Mycurit 3 Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep MYCURIT 3 TAB 1X10 away from the reach of children and pets.
• Store MYCURIT 3 TAB 1X10 at room temperature.

• **Take Mycurit 3 Tablet as Directed:** Always follow your doctor's instructions regarding dosage and timing. Do not self-medicate or alter the prescribed regimen without consulting your healthcare provider, even if you feel better.
• **Complete the Full Course:** Even if your symptoms improve quickly, it's crucial to complete the entire course of Mycurit 3 Tablet as prescribed. Stopping early can lead to a recurrence of the infection or the development of drug resistance. This ensures the infection is fully eradicated and prevents future complications.
• **Take with Food:** To minimize potential stomach upset, it is generally recommended to take Mycurit 3 Tablet with food. This helps to reduce nausea and improve absorption of the medication. Always adhere to your doctor's recommendations on how to take the medication.
• **Avoid Alcohol:** While taking Mycurit 3 Tablet, avoid consuming alcohol. Alcohol can interact with the medication, increasing the risk of side effects such as liver damage, nausea, and vomiting. Combining alcohol and this medication can also reduce the effectiveness of the treatment.
• **Be Aware of Potential Side Effects:** Be aware of potential side effects, such as nausea, vomiting, diarrhea, skin rash, or changes in liver function. If you experience any unusual or severe side effects, contact your doctor immediately. Early reporting allows for timely management and prevents serious complications. Regular monitoring, especially liver function tests, may be advised during treatment.
• **Store Properly:** Store Mycurit 3 Tablet in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children. Proper storage helps maintain the medication's effectiveness and prevents accidental ingestion.
• **Inform Your Doctor About Other Medications:** Before starting Mycurit 3 Tablet, inform your doctor about all other medications, supplements, and herbal products you are taking. This helps to avoid potential drug interactions that could affect the medication's effectiveness or increase the risk of side effects. This includes over-the-counter medications as well.

• MYCURIT 3 Tablet 10'S can be taken with or without food. However, it is generally recommended to take it after food to avoid stomach upset. Avoid taking it with grapefruit juice as it may increase the concentration of the medicine in your blood.