NEBISTAR LN 2.5MG TABLET 10'S

How NEBISTAR LN 2.5MG TABLET 10'S Works

• NEBISTAR LN 2.5MG TABLET 10'S is a combination medication designed to manage high blood pressure and related heart conditions. It contains two active ingredients: Nebivolol and S-Amlodipine. Each component works through different mechanisms to achieve a synergistic effect in lowering blood pressure and improving cardiovascular health.
• Nebivolol is a beta-blocker, specifically a beta-1 selective adrenergic receptor blocker. This means it primarily targets beta-1 receptors located in the heart. By blocking these receptors, Nebivolol slows down the heart rate and reduces the force with which the heart contracts. This leads to a decrease in cardiac output, which is the amount of blood the heart pumps out per minute. A lower cardiac output results in lower blood pressure. Additionally, Nebivolol has a unique property of stimulating the release of nitric oxide (NO) from the endothelial cells lining the blood vessels. Nitric oxide is a vasodilator, meaning it helps to relax and widen blood vessels, further contributing to the reduction in blood pressure. This dual action of reducing cardiac output and promoting vasodilation makes Nebivolol an effective component in managing hypertension.
• S-Amlodipine, on the other hand, is a calcium channel blocker. It works by blocking the entry of calcium ions into the smooth muscle cells of the blood vessel walls and heart muscle cells. Calcium ions are essential for muscle contraction. By reducing the calcium influx, S-Amlodipine causes the smooth muscles in the blood vessel walls to relax, leading to vasodilation. This vasodilation reduces the resistance against which the heart has to pump, thereby lowering blood pressure. Furthermore, S-Amlodipine's action on the heart muscle cells helps to reduce the force of contraction, contributing to a further decrease in blood pressure.
• The combination of Nebivolol and S-Amlodipine in NEBISTAR LN 2.5MG TABLET 10'S provides a comprehensive approach to managing hypertension. Nebivolol reduces cardiac output and promotes vasodilation through nitric oxide release, while S-Amlodipine induces vasodilation by blocking calcium channels. This dual mechanism helps to effectively lower blood pressure and reduce the workload on the heart. This combination is particularly useful for individuals who require multiple mechanisms of action to control their blood pressure effectively, potentially reducing the need for multiple medications and improving adherence to the treatment regimen. Always take this medication as prescribed by your healthcare provider.

The following side effects may occur with NEBISTAR LN 2.5MG TABLET: **Common Side Effects:** * Headache * Dizziness * Fatigue * Nausea * Diarrhea * Constipation * Cold extremities (hands and feet) * Slow heart rate * Low blood pressure **Uncommon Side Effects:** * Sleep disturbances (insomnia) * Nightmares * Depression * Anxiety * Visual disturbances * Bronchospasm (wheezing) * Dyspnea (shortness of breath) * Impotence * Skin rash * Itching * Muscle cramps * Peripheral edema (swelling of ankles and feet) * AV block (a type of heart rhythm problem) * Exacerbation of intermittent claudication (leg pain on exertion) **Rare Side Effects:** * Dry mouth * Hallucinations * Psychosis * Confusion * Thrombocytopenia (low platelet count) * Raynaud's phenomenon (reduced blood flow to fingers and toes) **Very Rare Side Effects:** * Allergic reactions * Hepatitis (liver inflammation) **If you experience any of these side effects, especially if they are severe or persistent, consult your doctor.**

• If you miss a dose of NEBISTAR LN 2.5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEBISTAR LN 2.5MG TAB 1X10 away from the reach of children and pets.
• Store NEBISTAR LN 2.5MG TAB 1X10 at room temperature.

• Take NEBISTAR LN 2.5MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen maximizes its effectiveness in managing your condition.
• NEBISTAR LN 2.5MG TABLET 10'S can be taken with or without food, but try to take it at the same time each day to maintain a consistent level of medication in your system. This helps in better management of blood pressure and heart rate.
• Inform your doctor about all other medications, supplements, or herbal remedies you are currently taking before starting NEBISTAR LN 2.5MG TABLET 10'S. This medication can interact with other substances, potentially affecting its efficacy or increasing the risk of side effects. Common interactions include other blood pressure medications, certain antidepressants, and some heart medications.
• Monitor your blood pressure and heart rate regularly while taking NEBISTAR LN 2.5MG TABLET 10'S. Keep a record of these measurements and share them with your doctor during check-ups. This data helps your doctor assess how well the medication is working and adjust your treatment plan if necessary. If you notice significant changes or experience unusual symptoms, contact your doctor promptly.
• Be aware of potential side effects such as dizziness, fatigue, or slow heart rate. If you experience any of these side effects, especially if they are persistent or bothersome, inform your doctor. Avoid sudden changes in posture, especially when getting up from a sitting or lying position, to minimize dizziness. Stay hydrated and maintain a balanced diet to help manage potential side effects. If you experience any serious side effects such as shortness of breath or chest pain, seek immediate medical attention.

• NEBISTAR LN 2.5MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels.