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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Common side effects of Nebistar SA Tablet may include headache, dizziness, fatigue, and nausea. Some individuals might experience slow heartbeat, low blood pressure, shortness of breath, and swelling in the ankles or feet. Less common side effects can include diarrhea, constipation, vomiting, skin rash, itching, and visual disturbances. In rare cases, Nebistar SA Tablet can cause Raynaud's phenomenon (numbness and coldness in fingers and toes), worsening of psoriasis, and confusion or hallucinations. If you experience any severe or persistent side effects, it is crucial to consult your doctor.

Heart and circulation
Use under specialist supervisionNebistar SA affects heart rate, cardiac contractility, and vascular tone, and must be used carefully in patients with pre-existing heart disease.
Nebistar SA Tablet 15's contains nebivolol as an active ingredient. It is primarily used to treat hypertension (high blood pressure).
Nebistar SA Tablet 15's works by relaxing blood vessels and slowing down the heart rate, which lowers blood pressure.
Common side effects of Nebistar SA Tablet 15's include dizziness, fatigue, headache, and slow heart rate.
Nebistar SA Tablet 15's can be taken with or without food, but it's best to take it at the same time each day.
If you miss a dose of Nebistar SA Tablet 15's, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Stopping Nebistar SA Tablet 15's abruptly can cause a sudden increase in blood pressure, so it is advisable to gradually reduce the dose.
Nebistar SA Tablet 15's can interact with certain other medications, such as some heart medications, antidepressants, and antifungals. Consult your doctor before starting any new medication.
The safety of taking Nebistar SA Tablet 15's during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.
It is not known whether Nebistar SA Tablet 15's passes into breast milk. Consult your doctor before breastfeeding.
Nebistar SA Tablet 15's should be stored at room temperature, away from heat and moisture. Keep it out of the reach of children.
Yes, Nebistar SA Tablet 15's can be used to treat heart failure, but only under the supervision of a doctor.
In some cases, Nebistar SA Tablet 15's can affect sexual ability. Talk to your doctor if you are concerned about this.
Symptoms of an overdose of Nebistar SA Tablet 15's may include slow heart rate, low blood pressure, difficulty breathing, and fainting.
Drinking alcohol while taking Nebistar SA Tablet 15's can increase its blood pressure-lowering effect and increase the risk of side effects such as dizziness. It is advisable to avoid alcohol.
It may take a few weeks to see the full effects of Nebistar SA Tablet 15's. It is important to monitor your blood pressure regularly and follow your doctor's instructions.
Nebistar SA is primarily used to treat high blood pressure (essential hypertension) in adults. It combines nebivolol, a beta-blocker, and S-amlodipine, a calcium channel blocker, to lower blood pressure by slowing the heart rate, reducing the force of heart contractions, and relaxing blood vessels. Adequate blood pressure control helps reduce the risk of stroke, heart attack, and other cardiovascular complications.
Nebistar SA contains two active components. Nebivolol selectively blocks beta-1 receptors in the heart, which slows the heart rate and decreases the heart’s workload. It also promotes nitric oxide–mediated vasodilation, helping blood vessels relax. S-amlodipine blocks L-type calcium channels in vascular smooth muscle, leading to dilation of peripheral arteries and reduced vascular resistance. The combined effect is a sustained reduction in blood pressure.
Nebistar SA can generally be taken with or without food. However, it is advisable to take it at the same time each day in a consistent manner, either always with food or always without, to maintain stable absorption. Patients should follow the specific instructions provided by their doctor or on the dispensing label and should not alter the timing or conditions of intake without medical advice.
If you miss a dose of Nebistar SA, take it as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may cause excessive lowering of blood pressure or heart rate. If you frequently forget doses, discuss strategies with your healthcare provider.
Common side effects of Nebistar SA may include headache, dizziness, fatigue, drowsiness, slow heart rate, flushing, ankle or leg swelling, palpitations, nausea, abdominal discomfort, and sleep disturbances. Mild side effects often improve as the body adjusts to treatment. However, if side effects are persistent, troublesome, or severe, such as marked slowing of the heart rate, severe dizziness, breathing difficulty, or significant swelling, medical attention is required.
Nebistar SA can be used in some patients with diabetes, but it requires careful monitoring. Beta-blockers like nebivolol may mask certain symptoms of low blood sugar, such as palpitations and tremors, making hypoglycaemia harder to recognize. Blood glucose levels should be monitored regularly, and antidiabetic therapy may need adjustment. Patients with diabetes should inform their doctor before starting Nebistar SA and report any unusual symptoms promptly.
Nebistar SA should not be stopped abruptly, even if blood pressure becomes well controlled. Sudden discontinuation of beta-blockers can lead to rebound increases in blood pressure, rapid heart rate, or worsening of underlying heart disease. Any change in therapy, including dose reduction or discontinuation, must be done gradually and only under medical supervision. Your doctor will decide if and when it is appropriate to adjust or stop the medicine.
Yes, ankle or leg swelling (peripheral oedema) can occur with S-amlodipine, one of the components of Nebistar SA, due to dilation of peripheral blood vessels. Mild swelling is relatively common and may be dose-related. If swelling is significant, painful, associated with shortness of breath, or rapidly worsening, you should contact your doctor, as dose adjustment, evaluation for heart or kidney issues, or a change in therapy may be necessary.
Use of Nebistar SA during pregnancy is generally not recommended unless the potential benefit clearly outweighs the potential risk to the fetus. Both nebivolol and S-amlodipine may affect fetal circulation and growth. Pregnant women or those planning to become pregnant should inform their doctor before starting this medicine. The doctor may consider alternative antihypertensive agents with a better-established safety profile in pregnancy.
Nebistar SA is not known to be habit-forming or addictive. It does not produce euphoria or craving. However, it is a long-term cardiovascular medication that should be taken regularly as prescribed. Stopping or altering the dose without medical guidance can be harmful, even though the medicine itself does not cause dependence in the conventional sense.
Alcohol can enhance the blood pressure–lowering effect of Nebistar SA and may increase the risk of dizziness, light-headedness, or fainting, especially when standing up quickly. It is advisable to limit or avoid alcohol consumption while on this medicine. Patients who choose to drink should do so cautiously and be alert to symptoms of low blood pressure. Discuss alcohol use with your doctor for individualized advice.
Nebistar SA can be used in elderly patients, but they may be more sensitive to its blood pressure–lowering and heart rate–reducing effects. Treatment is usually started cautiously, with close monitoring of blood pressure, heart rate, kidney function, and any symptoms such as dizziness, falls, or worsening shortness of breath. Dose adjustments may be required based on tolerance and clinical response.
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LUPIN LIMITED
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India
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