NEOSURF 100MG INJECTION 3 ML
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NEOSURF 100MG INJECTION 3 ML
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NEOSURF 100MG INJECTION 3 ML

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NEOSURF 100MG INJECTION 3 ML

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

7082

₹7082

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About NEOSURF 100MG INJECTION 3 ML

  • NEOSURF 100MG INJECTION 3 ML is a sterile, non-pyrogenic preparation designed to reduce surface tension in the lungs. It contains a phospholipid-rich fraction of bovine lung extract. This injection is primarily used in the treatment of respiratory distress syndrome (RDS) in premature infants. RDS is a condition where the lungs lack a naturally occurring substance called surfactant, which helps keep the air sacs in the lungs open.
  • The active ingredients in NEOSURF work by replacing the missing surfactant in the infant's lungs. This replacement reduces the surface tension in the alveoli (air sacs), allowing the lungs to inflate more easily and improving oxygen exchange. By improving lung function, NEOSURF helps to reduce the work of breathing and improve oxygenation in premature infants with RDS.
  • NEOSURF 100MG INJECTION is administered directly into the infant's trachea (windpipe) by a qualified healthcare professional. The dosage is determined based on the infant's weight and clinical condition. Following administration, the infant is closely monitored for improvements in respiratory function and oxygen saturation. This medication is an important tool in neonatal intensive care units, contributing significantly to improved outcomes for premature infants at risk of or suffering from respiratory distress syndrome.
  • It is crucial to note that NEOSURF should only be administered by trained medical personnel in a controlled hospital setting. Side effects are possible, and healthcare providers are equipped to manage them promptly. Regular monitoring of the infant's respiratory status and overall condition is essential during and after NEOSURF administration to ensure the best possible outcome.

Uses of NEOSURF 100MG INJECTION 3 ML

  • Treatment of Respiratory Distress Syndrome (RDS) in newborns.
  • Improving lung function by reducing surface tension.
  • Supporting lung function in premature infants.
  • Improving survival rates in infants with RDS.
  • Reducing the need for oxygen and ventilators.
  • Reducing lung injury that can occur from ventilation.
  • Opening and stabilizing the lungs in infants with surfactant deficiency.
  • Reducing complications associated with RDS.

How NEOSURF 100MG INJECTION 3 ML Works

  • NEOSURF 100MG INJECTION 3 ML contains Surfactant, a naturally occurring substance in the lungs. Its primary function is to reduce surface tension in the alveoli, the tiny air sacs in the lungs where gas exchange occurs. In premature infants, particularly those born before 34 weeks of gestation, the lungs may not have developed sufficiently to produce enough surfactant on their own. This deficiency leads to a condition called Infant Respiratory Distress Syndrome (IRDS), also known as Hyaline Membrane Disease.
  • In IRDS, the lack of surfactant causes the alveoli to collapse upon exhalation. This collapse makes it extremely difficult for the infant to breathe, requiring them to exert a great deal of effort with each breath. The increased effort can lead to exhaustion and respiratory failure. Furthermore, the collapsed alveoli reduce the surface area available for gas exchange, leading to decreased oxygen levels in the blood and increased carbon dioxide levels.
  • NEOSURF 100MG INJECTION 3 ML works by replenishing the deficient surfactant in the infant's lungs. When administered, the surfactant molecules spread across the surface of the alveoli, reducing surface tension. This allows the alveoli to remain open, or at least partially open, at the end of exhalation. By preventing alveolar collapse, NEOSURF 100MG INJECTION 3 ML significantly reduces the effort required for the infant to breathe.
  • The reduction in breathing effort allows the infant to conserve energy and reduces the risk of respiratory failure. Furthermore, with the alveoli remaining open, a greater surface area is available for gas exchange. This leads to improved oxygen levels in the blood and reduced carbon dioxide levels. Ultimately, NEOSURF 100MG INJECTION 3 ML helps to stabilize the infant's respiratory function, allowing them to breathe more easily and effectively, and supporting their overall health and development.
  • The administration of NEOSURF 100MG INJECTION 3 ML is typically performed by trained medical professionals in a neonatal intensive care unit (NICU). The injection is administered directly into the infant's trachea, usually via an endotracheal tube. The dosage and frequency of administration will depend on the infant's weight and the severity of their condition. Following administration, the infant's respiratory status will be closely monitored to assess their response to the treatment.
  • In summary, NEOSURF 100MG INJECTION 3 ML addresses IRDS by supplying the lungs with the necessary surfactant to reduce surface tension. This action prevents alveolar collapse, eases breathing effort, enhances gas exchange, and stabilizes respiratory function, thereby greatly improving the prognosis for premature infants suffering from this challenging condition.

Side Effects of NEOSURF 100MG INJECTION 3 MLArrow

Possible side effects of Neosurf 100mg Injection (Beractant) may include: * Breathing difficulties (apnea) * Slow heart rate (bradycardia) * Decreased oxygen saturation * Endotracheal tube blockage * Lung Hemorrhage * Mucus plugging * Pulmonary air leaks * Infection * Intracranial hemorrhage * Seizures * Acidosis Less common side effects may include: * Hypertension * Hypotension * Pallor * Peripheral vasoconstriction

Safety Advice for NEOSURF 100MG INJECTION 3 MLArrow

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Allergies

Allergies

Consult your doctor if you are allergic to NEOSURF 100MG INJECTION 3 ML.

Dosage of NEOSURF 100MG INJECTION 3 MLArrow

  • The recommended dosage of NEOSURF 100MG INJECTION 3 ML varies significantly depending on the patient's age, weight, medical condition, and the specific purpose of the treatment. It's crucial to adhere strictly to the dosage prescribed by your physician. This injection is typically administered intravenously by a healthcare professional in a hospital or clinical setting.
  • For neonates, the dosage is usually calculated based on their body weight and gestational age. The healthcare provider will carefully monitor the infant's response to the medication and adjust the dosage accordingly. The injection is administered slowly over a specified period, as determined by the doctor, to minimize the risk of side effects.
  • In adults, the dosage and frequency of administration depend on the severity and nature of the condition being treated. The physician will consider factors such as kidney function and other medications the patient is taking before determining the appropriate dose. Regular monitoring of blood parameters may be required to ensure the medication is effective and safe.
  • The duration of treatment with NEOSURF 100MG INJECTION 3 ML also varies. Some patients may require only a single dose, while others may need multiple doses over several days or weeks. It is essential to complete the full course of treatment as prescribed by your doctor, even if you start to feel better before the treatment is finished. Abruptly stopping the medication without consulting your doctor can lead to a relapse or worsening of your condition.
  • Take 'NEOSURF 100MG INJECTION 3 ML' only as per the prescription by your physician only. If you have any questions or concerns about your dosage, please consult with your doctor or pharmacist.

What if I miss my dose of NEOSURF 100MG INJECTION 3 ML?Arrow

  • As this medication is administered by a healthcare professional, the chances of missing a dose are low. However, if you believe you have missed a scheduled dose, inform your doctor or healthcare provider immediately to reschedule the dose as soon as possible.
  • Do not attempt to self-administer a missed dose.

How to store NEOSURF 100MG INJECTION 3 ML?Arrow

  • Keep NEOSURF 100MG INJ 3ML away from the reach of children and pets.
  • Store NEOSURF 100MG INJ 3ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of NEOSURF 100MG INJECTION 3 MLArrow

  • NEOSURF 100MG INJECTION 3 ML is a crucial medication primarily used to treat and prevent respiratory distress syndrome (RDS) in premature infants. RDS is a condition where a premature baby's lungs are not fully developed, leading to a deficiency in surfactant, a substance that helps keep the air sacs in the lungs open. By administering NEOSURF, we aim to improve lung function significantly.
  • The primary benefit of NEOSURF is the rapid improvement in oxygenation. Upon administration, it quickly spreads throughout the lungs, reducing surface tension and allowing the alveoli (air sacs) to inflate more easily. This results in improved gas exchange, leading to higher oxygen levels in the infant's blood and reduced need for supplemental oxygen.
  • NEOSURF reduces the work of breathing for premature infants. Without sufficient surfactant, each breath requires significant effort, leading to exhaustion and potential respiratory failure. By supplementing the infant's natural surfactant, NEOSURF decreases the effort needed for each breath, conserving energy and preventing respiratory muscle fatigue.
  • NEOSURF significantly lowers the risk of complications associated with RDS. These complications include pneumothorax (collapsed lung), pulmonary interstitial emphysema (air leaks in the lung tissue), and intraventricular hemorrhage (bleeding in the brain). By improving lung function and reducing the need for mechanical ventilation, NEOSURF helps minimize the occurrence of these serious issues.
  • Furthermore, NEOSURF reduces the need for and duration of mechanical ventilation. Mechanical ventilation, while life-saving, can also damage delicate premature lungs. NEOSURF often allows infants to breathe more effectively on their own, shortening the time they need to be on a ventilator, thereby reducing the risk of ventilator-induced lung injury.
  • Another key benefit is improved survival rates for premature infants with RDS. Clinical studies have consistently demonstrated that surfactant replacement therapy, such as with NEOSURF, leads to a significant increase in survival rates among premature babies struggling with respiratory distress. This is achieved through the combination of improved oxygenation, reduced complications, and decreased need for prolonged ventilation.
  • NEOSURF can lead to shorter hospital stays for premature infants. By effectively treating RDS and preventing its complications, NEOSURF contributes to a faster recovery. This can result in earlier discharge from the neonatal intensive care unit (NICU) and a reduced overall cost of care.
  • The medication promotes better long-term respiratory health. Early and effective treatment with NEOSURF can help prevent chronic lung disease, such as bronchopulmonary dysplasia (BPD), a condition that can cause long-term breathing difficulties. By supporting healthy lung development from the start, NEOSURF contributes to improved respiratory outcomes throughout the child's life.
  • NEOSURF is easy to administer via direct tracheal instillation, ensuring it reaches the lungs quickly and efficiently. Healthcare professionals administer it, and its targeted delivery minimizes systemic exposure, maximizing its therapeutic effect while reducing potential side effects.
  • Finally, NEOSURF aids in faster overall recovery and development. By minimizing the impact of RDS, premature infants can conserve energy and focus on growth and development. This can lead to improved weight gain, better neurological outcomes, and a smoother transition to independent living.

How to use NEOSURF 100MG INJECTION 3 MLArrow

  • NEOSURF 100MG INJECTION 3 ML is administered intravenously by a healthcare professional. It is typically given as a slow intravenous infusion to minimize potential side effects. The dosage and duration of treatment will depend on the patient's condition, weight, and response to therapy. Prior to administration, the solution should be visually inspected for particulate matter and discoloration. Do not use if the solution is cloudy or contains precipitates.
  • Before starting NEOSURF treatment, inform your doctor about your complete medical history, including any allergies, pre-existing conditions, and current medications. This information is crucial for determining the appropriate dosage and monitoring for potential interactions. Ensure that your healthcare provider is aware of any kidney or liver problems you may have, as these conditions can affect how your body processes the medication.
  • During the infusion, your healthcare provider will closely monitor your vital signs, including blood pressure, heart rate, and respiratory rate. This is to ensure your safety and to detect any adverse reactions early on. If you experience any unusual symptoms, such as difficulty breathing, chest pain, or swelling, inform your healthcare provider immediately.
  • After the infusion, follow your healthcare provider's instructions carefully. They may recommend certain dietary modifications or lifestyle changes to support your recovery. It's essential to attend all follow-up appointments to monitor your progress and adjust the treatment plan as needed. Report any persistent or worsening symptoms to your doctor promptly.
  • NEOSURF should only be used under the supervision of a qualified healthcare professional. Self-medication is strictly discouraged, as it can lead to serious health complications. If you have any questions or concerns about NEOSURF, consult your doctor or pharmacist for personalized guidance.

Quick Tips for NEOSURF 100MG INJECTION 3 MLArrow

  • **Use Under Medical Supervision:** NEOSURF 100MG INJECTION 3 ML should only be administered by trained healthcare professionals in a hospital or clinical setting. Self-administration is strictly prohibited due to the potential for serious side effects.
  • **Monitor Vital Signs:** During and after NEOSURF 100MG INJECTION 3 ML administration, closely monitor the patient's vital signs, including blood pressure, heart rate, and respiratory rate. Report any significant changes or abnormalities to the medical team immediately.
  • **Inform Your Doctor About Existing Conditions:** Before receiving NEOSURF 100MG INJECTION 3 ML, inform your doctor about all your existing medical conditions, including heart problems, kidney disease, liver disease, or any allergies. This will help them assess the risks and benefits of the medication.
  • **Be Aware of Potential Side Effects:** NEOSURF 100MG INJECTION 3 ML may cause side effects such as nausea, vomiting, headache, dizziness, or injection site reactions. Report any persistent or severe side effects to your doctor promptly. Also, inform your doctor if you experience any allergic reactions like rashes, itching, or swelling.
  • **Drug Interactions:** Inform your doctor or pharmacist about all other medicines, herbal products, and supplements you are currently taking before starting NEOSURF 100MG INJECTION 3 ML. This is important to avoid potential drug interactions that may affect the medication's effectiveness or increase the risk of side effects. Some medicines may interfere with how NEOSURF 100MG INJECTION 3 ML works.

Food Interactions with NEOSURF 100MG INJECTION 3 MLArrow

  • NEOSURF 100MG INJECTION 3 ML is administered by a healthcare professional, so food interactions are unlikely. However, always inform your doctor about all medications, supplements, and dietary habits before receiving the injection.

FAQs

What is Neosurf 100mg Injection 3ml used for?

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Neosurf 100mg Injection 3ml is used to treat Respiratory Distress Syndrome (RDS) in newborn infants.

How does Neosurf 100mg Injection 3ml work?

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Neosurf 100mg Injection 3ml works by replacing surfactant in the lungs, helping infants breathe more easily.

What is the usual dosage of Neosurf 100mg Injection 3ml?

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The dosage depends on the infant's weight and the severity of RDS. It should be determined by a doctor.

What are the common side effects of Neosurf 100mg Injection 3ml?

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Common side effects may include changes in heart rate, decreased oxygen saturation, and airway obstruction.

How should Neosurf 100mg Injection 3ml be stored?

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It should be stored according to the instructions on the label. Generally, it is refrigerated.

Can Neosurf 100mg Injection 3ml interact with other medications?

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It's important to inform the doctor about potential drug interactions.

Is Neosurf 100mg Injection 3ml safe for premature infants?

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Yes, Neosurf 100mg Injection 3ml is specifically designed to treat RDS in premature infants.

What to do in case of an overdose of Neosurf 100mg Injection 3ml?

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Neosurf 100mg Injection 3ml is administered by a healthcare professional, so overdose is unlikely. If there is a concern, seek immediate medical attention.

Can Neosurf 100mg Injection 3ml cure RDS in infants?

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Neosurf 100mg Injection 3ml helps reduce the symptoms of RDS and improves lung function, giving the infant time to recover.

How is Neosurf 100mg Injection 3ml administered?

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It is typically administered into the lungs through an endotracheal tube.

What is the difference between Neosurf and other surfactant replacement products?

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Neosurf is a synthetic surfactant, while other products may be animal-derived.

How are infants monitored during treatment with Neosurf 100mg Injection 3ml?

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Infants are closely monitored for heart rate, oxygen levels, and breathing.

May a repeat dose of Neosurf 100mg Injection 3ml be needed?

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In some cases, a repeat dose may be needed depending on the infant's response.

What happens if the infant does not improve after using Neosurf 100mg Injection 3ml?

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Other treatment options will be considered, and the infant's condition will be monitored more closely.

Can Neosurf 100mg Injection 3ml cause long-term health problems?

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Long-term effects of Neosurf 100mg Injection 3ml are not widely documented, but the short-term benefits outweigh the risk of RDS.

References

Book Icon

DailyMed - NEOSTIGMINE METHYLSULFATE injection. This provides detailed information including composition, indications, dosage, and adverse effects. While not specific to 'NEOSURF' (likely a brand variation), it covers Neostigmine Methylsulfate.

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DrugBank - Neostigmine. Comprehensive chemical and pharmacological information on Neostigmine, including its mechanism of action, pharmacokinetics, and interactions.

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PubMed Central. Search 'Neostigmine' to find research articles on its clinical use, pharmacology, and related studies.

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FDA Orange Book. Check for approved drug products containing Neostigmine Methylsulfate.

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UpToDate - Neostigmine drug information. Clinical information for healthcare professionals, including dosing, indications, and contraindications (requires subscription).

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CIPLA PHARMACEUTICAL COMPANY LIMITED

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NEOSURF 100MG INJECTION 3 ML

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