NEXITO LS TABLET 10'S

How NEXITO LS TABLET 10'S Works

• NEXITO LS TABLET 10'S is a combination medication designed to address symptoms of depression and anxiety by targeting multiple neurotransmitter systems in the brain. It contains two active ingredients: Escitalopram and Levosulpiride. Escitalopram is a selective serotonin reuptake inhibitor (SSRI), while Levosulpiride is an atypical antipsychotic with prokinetic properties.
• Escitalopram primarily works by increasing the levels of serotonin, a neurotransmitter responsible for regulating mood, emotions, and sleep. Serotonin is released by nerve cells in the brain and then reabsorbed. Escitalopram blocks this reabsorption process, allowing more serotonin to remain available in the synaptic cleft (the space between nerve cells). This enhanced serotonin activity helps to alleviate symptoms of depression and anxiety by improving mood, reducing feelings of sadness or hopelessness, and promoting a sense of well-being.
• Levosulpiride, on the other hand, exerts its effects through different mechanisms. It acts as a dopamine receptor antagonist, primarily blocking D2 dopamine receptors in the brain and gastrointestinal tract. By blocking dopamine receptors in the brain, Levosulpiride can help to improve mood and reduce anxiety symptoms. Additionally, its prokinetic properties stimulate gastrointestinal motility, which can be beneficial for individuals experiencing gastrointestinal disturbances related to anxiety or depression, such as nausea, bloating, or constipation. This dual action helps in comprehensive management of the condition.
• In summary, NEXITO LS TABLET 10'S works by combining the antidepressant effects of Escitalopram (increasing serotonin levels) with the anxiolytic and prokinetic effects of Levosulpiride (blocking dopamine receptors and promoting gastrointestinal motility). This synergistic action can provide more effective relief from the symptoms of depression and anxiety compared to using either medication alone. It's important to take this medication as prescribed by your doctor, and to be aware of potential side effects.
• The combination of Escitalopram and Levosulpiride in NEXITO LS provides a multi-faceted approach. Escitalopram elevates serotonin, improving mood regulation and reducing depressive symptoms. Simultaneously, Levosulpiride helps manage anxiety and related gastrointestinal issues by modulating dopamine activity and enhancing digestive function. This combined action can lead to a more comprehensive and effective treatment outcome for patients experiencing both depression and anxiety, addressing both psychological and physical symptoms that often accompany these conditions. Always consult with a healthcare professional for personalized medical advice and treatment.

Common side effects of Nexito LS Tablet may include nausea, constipation, vomiting, diarrhea, dry mouth, increased sweating, fatigue, drowsiness, insomnia (difficulty sleeping), anxiety, restlessness, decreased appetite, weight changes, blurred vision, dizziness, and sexual dysfunction (decreased libido, ejaculatory problems, erectile dysfunction). Uncommon side effects can include muscle pain or cramps, tremor, urinary retention, confusion, agitation, changes in heart rhythm (palpitations), increased blood pressure, and allergic reactions (rash, itching, swelling). Rare but serious side effects can include serotonin syndrome (symptoms include high fever, agitation, confusion, tremors, and rapid heart rate), neuroleptic malignant syndrome (symptoms include fever, muscle rigidity, altered mental status, and autonomic dysfunction), seizures, and suicidal thoughts or behavior. This is not an exhaustive list; other side effects may occur. Consult your doctor if you experience any concerning symptoms.

• If you miss a dose of NEXITO LS Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEXITO LS TAB 1X10 away from the reach of children and pets.
• Store NEXITO LS TAB 1X10 at room temperature.

• Take NEXITO LS TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting them, even if you feel better. This medication is usually taken once daily, with or without food, preferably at the same time each day to maintain consistent blood levels.
• NEXITO LS TABLET 10'S contains escitalopram and clonazepam, which can cause drowsiness or dizziness. Avoid driving, operating heavy machinery, or performing tasks that require alertness until you know how this medication affects you. Be cautious when standing up quickly from a sitting or lying position to minimize dizziness.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting NEXITO LS TABLET 10'S. This is crucial to avoid potential drug interactions. Pay special attention to other medications that also cause drowsiness or affect serotonin levels.
• Alcohol can increase the sedative effects of NEXITO LS TABLET 10'S. It is strongly advised to avoid or limit alcohol consumption while taking this medication to prevent excessive drowsiness and impaired coordination. The combination can also increase the risk of adverse effects.
• If you miss a dose of NEXITO LS TABLET 10'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Sudden discontinuation of this medication can lead to withdrawal symptoms; therefore, consult your doctor before stopping the medication.

• NEXITO LS TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent medicine levels in the body.