NGMINE 250MG INJECTION
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NGMINE 250MG INJECTION
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NGMINE 250MG INJECTION

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NGMINE 250MG INJECTION

By SAMARTH LIFE SCIENCES PRIVATE LIMITED

MRP

9350.6

₹7555

19.2 % OFF

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Product DetailsArrow

About NGMINE 250MG INJECTION

  • NGMINE 250MG INJECTION contains bivalirudin, a medication used in cardiology as an anticoagulant (blood thinner). It's often administered during procedures like percutaneous coronary intervention (PCI) or angioplasty to prevent blood clots. It serves as an alternative to heparin, especially for patients at risk of heparin-induced thrombocytopenia (HIT), a serious complication of heparin therapy.
  • This medication is not suitable for individuals with a known hypersensitivity or allergy to bivalirudin or any of its components. Due to its anticoagulant properties, it's contraindicated in patients with active, severe bleeding, such as gastrointestinal or intracranial bleeding, or those with bleeding disorders. It's also generally avoided in patients with severely uncontrolled high blood pressure (hypertension).
  • Patients with severe renal impairment or end-stage renal disease may need dosage adjustments or alternative anticoagulation strategies, as bivalirudin can accumulate, increasing bleeding risk. Caution is advised in patients with coagulation disorders or conditions that predispose them to bleeding.
  • NGMINE 250MG INJECTION is generally not recommended for patients with a significantly low platelet count (thrombocytopenia) or a history of heparin-induced thrombocytopenia (HIT), unless there are no other suitable options. It may not be appropriate for individuals who have recently undergone major surgery or experienced significant trauma due to the heightened risk of bleeding. It's also not typically used as the only anticoagulant in patients with infective endocarditis or other conditions requiring prolonged anticoagulation. While NGMINE 250MG INJECTION can be used in elderly patients, caution is advised. It is typically avoided in pediatric patients.
  • Before using NGMINE 250MG INJECTION, inform your doctor about any pre-existing medical conditions, allergies, and medications you are taking. Regular monitoring of blood parameters is necessary during treatment to ensure safety and effectiveness. If you experience any unusual bleeding or bruising, seek immediate medical attention. This medication should only be administered by qualified healthcare professionals in a controlled medical setting.
  • The use of NGMINE 250MG INJECTION should be carefully evaluated and prescribed by a healthcare provider experienced in managing anticoagulation therapy. They will consider your individual medical history, current health status, and the specific procedure being performed to determine the most appropriate treatment approach. It's crucial to follow your doctor's instructions precisely and attend all scheduled follow-up appointments.

Uses of NGMINE 250MG INJECTION

  • Percutaneous coronary intervention (PCI), a minimally invasive procedure used to open blocked coronary arteries, restoring blood flow to the heart. NGMINE 250MG INJECTION may be relevant in managing complications or supporting the procedure.
  • Heparin-induced thrombocytopenia (HIT), a serious immune reaction to heparin that causes a decrease in platelet count and increases the risk of blood clots. NGMINE 250MG INJECTION might be used as an alternative anticoagulant in patients with HIT.
  • Anticoagulation during cardiac surgery, where medications are needed to prevent blood clots from forming during and after the surgical procedure. NGMINE 250MG INJECTION could be considered within the anticoagulation strategy in specific cardiac surgery scenarios.

Side Effects of NGMINE 250MG INJECTIONArrow

Like all medications, NGMINE 250MG INJECTION can cause side effects, though not everyone experiences them.

  • Bleeding
  • Allergic reactions
  • Thrombosis
  • Bleeding
  • Pain at injection site
  • Headache

Safety Advice for NGMINE 250MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

NGMINE 250MG INJECTION may be used in pregnant women only if the potential benefits outweigh the risks and under the supervision of a healthcare provider.

Dosage of NGMINE 250MG INJECTIONArrow

  • NGMINE 250MG INJECTION is administered intravenously (IV). This means it is given directly into a vein. The precise method and rate of administration will be determined by your healthcare provider, who is trained to administer IV medications safely and effectively.
  • It is absolutely crucial to adhere to the dosing instructions specified on the product packaging or, more importantly, as explicitly directed by your healthcare provider. Never attempt to self-administer this medication.
  • The dosage will be carefully calculated based on individual factors such as your weight, kidney functions, the severity of your condition, and any other medications you may be taking. This personalized approach ensures optimal effectiveness and minimizes the risk of potential side effects. Therefore, any deviation from your doctor's recommendation may be dangerous.
  • If you have any questions or concerns regarding the administration or dosage of NGMINE 250MG INJECTION, please don't hesitate to consult your doctor or healthcare provider for clarification. They are the best resource for addressing any specific questions you might have.

How to store NGMINE 250MG INJECTION?Arrow

  • Keep NGMINE 250MG INJ away from the reach of children and pets.
  • Store NGMINE 250MG INJ at room temperature.

Benefits of NGMINE 250MG INJECTIONArrow

  • NGMINE 250MG INJECTION is a direct thrombin inhibitor, which means it works by directly blocking the action of thrombin. Thrombin is a key enzyme in the coagulation cascade, the process that leads to blood clot formation. By inhibiting thrombin, NGMINE 250MG INJECTION effectively prevents the conversion of fibrinogen into fibrin.
  • Fibrin is a protein that forms the mesh-like structure of a blood clot. When fibrinogen cannot be converted into fibrin, clot formation is significantly reduced. This mechanism is highly beneficial in various clinical settings where preventing or managing blood clots is crucial.
  • One of the primary uses of NGMINE 250MG INJECTION is during percutaneous coronary intervention (PCI). PCI is a procedure used to open blocked coronary arteries. During PCI, there is a risk of clot formation that can impede blood flow. NGMINE 250MG INJECTION helps maintain blood flow by preventing clot formation in the coronary arteries during the procedure.
  • The rapid onset and reversible effects of NGMINE 250MG INJECTION make it a valuable option in situations where anticoagulation is needed quickly and may need to be reversed. This allows for greater control over the patient's coagulation status during and after medical procedures.

How to use NGMINE 250MG INJECTIONArrow

  • NGMINE 250MG INJECTION is administered intravenously (IV), a method that ensures the medication is delivered directly into your bloodstream. This allows for rapid absorption and distribution throughout your body, enabling it to take effect quickly. The precise dosage and frequency of administration will be determined by your healthcare provider based on your individual needs, medical condition, and response to treatment.
  • It is crucial to adhere strictly to the dosing instructions provided by your doctor or found on the product packaging. Never attempt to self-administer this medication. It should only be given by a qualified healthcare professional in a clinical setting where appropriate monitoring and support are available.
  • The healthcare provider will carefully calculate the correct dose and administer it through a sterile IV line. They will also monitor you closely for any potential side effects or adverse reactions during and after the infusion. If you have any concerns or experience any unusual symptoms, inform your healthcare provider immediately.

FAQs

Is there an antidote for NGMINE 250MG INJECTION?Arrow

Unlike some other anticoagulants like heparin, NGMINE 250MG INJECTION does not have a specific antidote. In cases of severe bleeding or the need for rapid reversal, healthcare providers may use supportive measures, such as blood transfusions or other agents, to counteract its effects.

Can I discontinue NGMINE 250MG INJECTION on my own once my procedure is complete?Arrow

No, it is crucial to follow your healthcare provider's instructions regarding the discontinuation of NGMINE 250MG INJECTION. Stopping the medication abruptly without guidance can increase the risk of clot formation or other complications.

Are there any dietary restrictions while taking NGMINE 250MG INJECTION?Arrow

There are no specific dietary restrictions associated with NGMINE 250MG INJECTION. However, it's essential to maintain a balanced diet and stay hydrated, as overall health plays a role in recovery from medical procedures.

How long does the anticoagulant effect of NGMINE 250MG INJECTION last?Arrow

NGMINE 250MG INJECTION has a relatively short half-life, which allows for rapid onset and offset of its anticoagulant effects. The duration of its effect can vary depending on the dosage and individual patient factors.

What should I do if I miss a dose of NGMINE 250MG INJECTION?Arrow

NGMINE 250MG INJECTION is typically administered under medical supervision, so the likelihood of missing a dose is minimal. However, if you have concerns about missed doses, discuss them with your healthcare provider for guidance on how to proceed.

What are the common side effects of NGMINE 250MG INJECTION?Arrow

Common side effects of NGMINE 250MG INJECTION can include bleeding (both minor and major), pain at the injection site, and headache.

Does NGMINE 250MG INJECTION interact with other drugs?Arrow

There is no specific data available on how NGMINE 250MG INJECTION interacts with other drugs. It is important to tell your doctor about all the medications you are taking to avoid any potential interactions.

What precautions should I take while taking NGMINE 250MG INJECTION?Arrow

NGMINE 250 mg injection increases the risk of bleeding, so careful monitoring is crucial, especially in patients with kidney problems who may need dosage adjustments. While it has minimal impact on liver function, severe liver disease should still be monitored. Verify any allergies to heparin and take steps to prevent blood clot formation with appropriate dosing and monitoring. Be cautious of potential drug interactions, be prepared to manage allergic reactions, and use this medication during pregnancy or breastfeeding only when the benefits outweigh the risks. Limited data are available for pediatric use, and elderly patients may require extra monitoring. Additionally, be careful with alcohol consumption and avoid driving or operating heavy machinery if experiencing dizziness or other side effects.

What is Bivalirudin and why is it used in NGMINE 250MG INJECTION?Arrow

Bivalirudin is a molecule used for making NGMINE 250MG INJECTION. It is an anticoagulant, meaning it helps prevent blood clots from forming.

How is NGMINE 250MG INJECTION used for cardiology conditions?Arrow

NGMINE 250MG INJECTION is an anticoagulant, meaning it helps prevent blood clots from forming. It is used during cardiology procedures and in people with certain heart conditions to prevent blood clot formation.

References

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Medicines company, US Food and Drug Administration

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Accord Healthcare, Electronics Medicine compendium (EMC)

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Ratings & Review

Amazing service and customer friendly

Deepak Patel

Reviewed on 05-11-2022

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(3/5)

Good representation and good communication to the cx very helpfull

Sunny Mack

Reviewed on 02-02-2024

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(5/5)

Had a good experience when I went for purchasing medicine. Appreciate the service

Chitrang Shah

Reviewed on 07-11-2022

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(5/5)

Excellent service

Ali Akhtar

Reviewed on 26-07-2023

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(5/5)

All drugs available good service

Jayvadan Lalpara

Reviewed on 23-01-2024

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(5/5)


Marketer / Manufacturer Details

SAMARTH LIFE SCIENCES PRIVATE LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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