NIKORAN OD 10MG TABLET 10'S

How NIKORAN OD 10MG TABLET 10'S Works

• NIKORAN OD 10MG TABLET 10'S is a medication primarily used to manage and prevent angina pectoris, a condition characterized by chest pain or discomfort due to insufficient blood supply to the heart. Its effectiveness stems from the unique dual action mechanism of its active ingredient, Nicorandil.
• Firstly, Nicorandil functions as a potassium channel activator. It opens ATP-sensitive potassium channels in vascular smooth muscle cells. This action leads to the hyperpolarization of these cells, making them less likely to contract. As a result, blood vessels, particularly arteries and arterioles, relax and dilate. This vasodilation reduces the resistance against which the heart has to pump, decreasing the heart's workload and oxygen demand.
• Secondly, Nicorandil has a nitrate-like effect. It gets converted into nitric oxide (NO) within the body. Nitric oxide is a potent vasodilator. It stimulates the production of cyclic GMP (cGMP), a signaling molecule that causes smooth muscle relaxation in blood vessels. This further enhances the dilation of coronary arteries, improving blood flow to the heart muscle. The increased blood flow ensures that the heart receives an adequate supply of oxygen, alleviating and preventing angina symptoms.
• The combined action of potassium channel activation and nitrate-like effects makes NIKORAN OD 10MG TABLET 10'S particularly effective. By reducing both the heart's workload and increasing oxygen supply, it provides relief from chest pain and improves exercise tolerance in individuals with angina. The 'OD' in the name indicates that it is an 'Once Daily' formulation, designed for sustained release of the medication over an extended period, providing a consistent therapeutic effect throughout the day with a single dose.
• In summary, NIKORAN OD 10MG TABLET 10'S works by relaxing blood vessels (both arteries and veins) to reduce the heart's workload (afterload and preload) and by directly dilating the coronary arteries to increase blood flow to the heart muscle. This dual mechanism helps to restore the balance between oxygen supply and demand in the heart, preventing and relieving the symptoms of angina.

Common side effects of NIKORAN OD 10MG TABLET may include headache, dizziness, nausea, vomiting, and flushing. Less common side effects can involve palpitations, weakness, mouth ulcer, skin rashes, itching, and low blood pressure. Serious but rare side effects may include severe allergic reactions (anaphylaxis) and significant drops in blood pressure leading to fainting. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of NIKORAN OD 10MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NIKORAN OD 10MG TAB 1X10 away from the reach of children and pets.
• Store NIKORAN OD 10MG TAB 1X10 in a refrigerator (2 - 8°C). Do not freeze.

• Take NIKORAN OD 10MG TABLET 10'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water. It's usually taken once daily, but your doctor will determine the best dosage and timing for you. Consistency is key for optimal effectiveness.
• Avoid grapefruit and grapefruit juice while taking NIKORAN OD 10MG TABLET 10'S. Grapefruit can interact with the medication, potentially increasing the levels of the drug in your bloodstream and raising the risk of side effects. Check with your doctor or pharmacist if you're unsure about other foods or beverages.
• If you experience dizziness or lightheadedness after taking NIKORAN OD 10MG TABLET 10'S, sit or lie down until the feeling passes. This is a common side effect, especially when you first start taking the medication. Avoid driving or operating machinery until you know how the medicine affects you. Staying hydrated can also help.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting NIKORAN OD 10MG TABLET 10'S. Drug interactions can affect how NIKORAN OD 10MG TABLET 10'S works and increase the risk of side effects. This includes over-the-counter medications as well.
• Do not stop taking NIKORAN OD 10MG TABLET 10'S without consulting your doctor, even if you feel better. Stopping the medication suddenly can worsen your condition. Your doctor will gradually reduce the dosage if necessary. Regular check-ups are important to monitor your progress and adjust your treatment plan as needed.

• NIKORAN OD 10MG TABLET 10'S can be taken with or without food. There are no specific food interactions known for this medication. However, it's always a good practice to maintain a consistent dietary pattern while taking any medication. If you experience any stomach upset, you may find it helpful to take it with food.