NINTENIB 100 CAPSULE 10'S
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NINTENIB 100 CAPSULE 10'S
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NINTENIB 100 CAPSULE 10'S

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NINTENIB 100 CAPSULE 10'S

By BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

MRP

750

₹637.5

15 % OFF

₹63.75 Only /

CAPSULE

10

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Product DetailsArrow

About NINTENIB 100 CAPSULE 10'S

  • NINTENIB 100 CAPSULE 10'S contains the active ingredient Nintedanib, a tyrosine kinase inhibitor used in the treatment of idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung disease, and systemic sclerosis-associated interstitial lung disease. If you are taking blood-thinning medications or have recently had surgery, consult your doctor before starting this medication. It is crucial to use effective contraception while taking this capsule and for three months after the final dose. Due to potential interactions that can reduce their effectiveness, birth control pills may not be the most reliable option; therefore, discuss alternative contraception methods with your healthcare provider.
  • Before commencing treatment with NINTENIB 100 CAPSULE 10'S, inform your doctor about any pre-existing medical conditions, especially liver or heart problems. Your doctor may order liver function tests at regular intervals during the first three months of treatment to monitor your liver health. It is also important to inform your doctor if you have a history of bleeding disorders or blood clots (arterial thromboembolic events). NINTENIB 100 CAPSULE 10'S has the potential to cause liver function impairment (hepatic impairment) and embryo-fetal toxicity, so caution is advised.
  • It is essential to consult your doctor about any underlying health conditions you may have. Common side effects associated with NINTENIB 100 CAPSULE 10'S include nausea, vomiting, diarrhea, fever, skin ulcers, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss, and hypertension. Seek immediate medical attention if you experience any concerning side effects. Regular monitoring and open communication with your healthcare provider are important to manage potential adverse reactions effectively and ensure the safe use of this medication.

Uses of NINTENIB 100 CAPSULE 10'S

  • Idiopathic pulmonary fibrosis, a chronic and progressive lung disease characterized by the thickening and scarring of lung tissue, leading to impaired breathing and reduced oxygen levels in the blood. This condition's cause is often unknown.
  • Chronic fibrosing lung diseases that exhibit a progressive phenotype, indicating a gradual worsening of lung function and an increase in fibrosis over time. These diseases often have complex underlying mechanisms.
  • Systemic sclerosis, also known as scleroderma, is a chronic autoimmune disease that affects the connective tissue, leading to fibrosis in the skin, blood vessels, and internal organs, including the lungs.

Side Effects of NINTENIB 100 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects include bronchitis, myocardial infarction, bleeding problems, pneumonia, major bleeding, yellow eyes, dark urine, pain in the upper right side of the stomach, severe stomach cramps, bloating, fever, and chills, chest pressure or pain on the left side of the body and increased protein in the urine (proteinuria). Common side effects include nausea, vomiting, diarrhea, fever, skin ulcer, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss and hypertension.

  • Bronchitis
  • Myocardial infarction
  • Bleeding problems
  • Pneumonia
  • Major bleeding
  • Yellow eyes, dark urine, pain in the upper right side of the stomach
  • Severe stomach cramps, bloating, fever, and chills
  • Chest pressure or pain on the left side of the body
  • Increased protein in the urine (proteinuria)
  • Nausea, vomiting, diarrhea
  • Fever
  • Skin ulcer
  • Gastrointestinal perforation
  • Altered liver function values
  • Decreased appetite
  • Headache
  • Weight loss
  • Hypertension

Safety Advice for NINTENIB 100 CAPSULE 10'SArrow

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Pregnancy

UNSAFE

NINTENIB 100 CAPSULE 10'S is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment.

Dosage of NINTENIB 100 CAPSULE 10'SArrow

  • Take NINTENIB 100 CAPSULE 10'S exactly as your physician prescribes. Adhere strictly to their guidance for optimal results. This medication is intended for oral administration. Ensure you swallow the capsule whole with a full glass of water. It is crucial that you do not crush, chew, break, or open the capsule, as this could affect the way the medicine is released and absorbed in your body.
  • The dosage and duration of treatment with NINTENIB 100 CAPSULE 10'S will be determined by your doctor, considering factors such as your age, body weight, overall health status, and the specific condition being treated. It is essential to follow their instructions precisely and complete the full course of treatment, even if you start feeling better.
  • Do not discontinue taking NINTENIB 100 CAPSULE 10'S without first consulting your doctor. Abruptly stopping the medication may lead to a worsening of your condition or the development of withdrawal symptoms. If you have any concerns or experience any side effects, inform your doctor promptly.

How to store NINTENIB 100 CAPSULE 10'S?Arrow

  • Keep NINTENIB 100MG CAP 1X10 away from the reach of children and pets.
  • Store NINTENIB 100MG CAP 1X10 at room temperature.

Benefits of NINTENIB 100 CAPSULE 10'SArrow

  • NINTENIB 100 CAPSULE 10'S works by targeting and inhibiting multiple receptor tyrosine kinases (RTKs) enzymes. These RTKs play a crucial role in the development and progression of lung fibrosis, a condition characterized by the excessive scarring of lung tissue. By inhibiting these enzymes, NINTENIB 100 CAPSULE 10'S effectively reduces the formation and accumulation of fibrous tissue in the lungs, helping to slow down the progression of the disease. This targeted approach helps to preserve lung function and improve the quality of life for individuals affected by lung fibrosis. The medication's mechanism of action focuses on interrupting the signaling pathways that promote fibrosis, offering a therapeutic benefit by limiting the extent of scarring and its associated respiratory complications.
  • By specifically blocking the activity of RTKs, NINTENIB 100 CAPSULE 10'S addresses the underlying mechanisms driving lung fibrosis. This can lead to a reduction in symptoms such as shortness of breath and coughing, as well as improved lung capacity and overall respiratory function. The medication is designed to interfere with the fibrotic process at a cellular level, providing a targeted approach to managing the disease. Clinical studies have shown that NINTENIB 100 CAPSULE 10'S can significantly slow the decline in lung function associated with fibrosis, offering patients a valuable treatment option.

How to use NINTENIB 100 CAPSULE 10'SArrow

  • Always take NINTENIB 100 CAPSULE 10'S exactly as your doctor has advised. It is crucial to follow their instructions precisely for the best possible outcome. If you have any doubts or uncertainties, don't hesitate to consult your doctor or pharmacist for clarification.
  • Swallow the capsule whole with a full glass of water. Avoid crushing, chewing, or opening the capsule, as this could affect how the medication is absorbed and works in your body. Taking it whole ensures that the medication is released properly.
  • Your doctor will determine the most appropriate dosage and treatment duration based on your individual circumstances, including your age, body weight, and the specific characteristics of your condition. It's essential to adhere to their prescribed regimen diligently.
  • Consistency is key to the effectiveness of NINTENIB 100 CAPSULE 10'S. Try to take it at the same time each day to maintain a steady level of the medication in your system. This will help optimize its therapeutic benefits.
  • Do not discontinue taking NINTENIB 100 CAPSULE 10'S without first consulting your doctor. Even if you start to feel better, it's important to complete the full course of treatment as prescribed. Stopping prematurely could lead to a relapse or other complications. If you experience any troublesome side effects, discuss them with your doctor, who may adjust your dosage or recommend alternative treatments.

FAQs

How does NINTENIB 100 CAPSULE 10'S work in the body?Arrow

NINTENIB 100 CAPSULE 10'S works by inhibiting several signaling pathways involved in the formation of scar tissue in the lungs. It targets the activity of certain enzymes and growth factors that promote the growth of fibroblasts, which are the cells responsible for producing collagen and other proteins that form scar tissue in the lungs.

Can NINTENIB 100 CAPSULE 10'S cure idiopathic pulmonary fibrosis (IPF)?Arrow

This medicine is not a cure for idiopathic pulmonary fibrosis (IPF). It is a medication that can help slow the progression of the disease by reducing the formation of scar tissue in the lungs. It is important to continue taking NINTENIB 100 CAPSULE 10'S as your doctor prescribes, even if you start feeling better.

How can I manage diarrhea while taking NINTENIB 100 CAPSULE 10'S?Arrow

If you experience diarrhea while taking NINTENIB 100 CAPSULE 10'S, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter medications or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.

Can NINTENIB 100 CAPSULE 10'S cause liver damage?Arrow

Nintedanib may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking NINTENIB 100 CAPSULE 10'S. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

What dosage of NINTENIB 100 CAPSULE 10'S should I take?Arrow

Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking NINTENIB 100 CAPSULE 10'S unless your doctor advises you to stop. As with all medications, it is important to follow the dosage instructions provided by your healthcare provider and to consult them for any questions or concerns.

Why is liver enzyme getting elevated during treatment with NINTENIB 100 CAPSULE 10'S?Arrow

The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the NINTENIB 100 CAPSULE 10'S.

NULL interaction of NINTENIB 100 CAPSULE 10'S with other drugsArrow

There are no known interactions of NINTENIB 100 CAPSULE 10'S with other drugs.

What advice should I follow while taking NINTENIB 100 CAPSULE 10'S?Arrow

Inform your physician if you have bleeding problems, hypertension, heart problems or weak blood vessels. Inform your physician if you experience allergic reactions to NINTENIB 100 CAPSULE 10'S. Notify your physician if you have recently undergone a surgery as this medicine affects the process of wound healing. Consult your physician and use an effective method of contraception while on this treatment and even after the treatment for three months. Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor. Avoid smoking while taking NINTENIB 100 CAPSULE 10'S because it may reduce the effectiveness of the medicine.

What is NINTENIB 100 CAPSULE 10'S made of?Arrow

NINTEDANIB is molecule/combination used for making NINTENIB 100 CAPSULE 10'S.

For which ailments/diseases/conditions is NINTENIB 100 CAPSULE 10'S typically prescribed?Arrow

NINTENIB 100 CAPSULE 10'S is typically prescribed for ailments/diseases/conditions related to Oncology.

References

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Boehringer Ingelheim Pharmaceuticals. Inc

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Boehringer Ingelheim, Electronics Medicines Compendium (EMC)

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Boehringer Ingelheim, U.S. Food and Drug Administration

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Lutz Wollin et al., Mode of action of Nintedanib capsule in the treatment of idiopathic pulmonary fibrosis, Eur Respir J. 2015 May; 45(5): 1434–1445

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Marketer / Manufacturer Details

BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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