nise 100mg tablet 15's
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NISE 100MG TABLET 15'S

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NISE 100MG TABLET 15'S

By DR REDDY'S LABORATORIES LIMITED

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134.53

₹114.35

15 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About NISE 100MG TABLET 15'S

  • Nise tablet is a brand of nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used for short-term relief of pain and inflammation. It is commonly prescribed for conditions such as acute pain, dental pain, musculoskeletal pain, painful periods (dysmenorrhea), and sometimes for pain associated with osteoarthritis or soft tissue injuries, when other safer options are not suitable or effective. Nimesulide works mainly by inhibiting cyclo-oxygenase (COX) enzymes and reducing the production of prostaglandins, substances in the body that cause pain, swelling, and fever. Because of its potential to cause serious side effects, especially on the liver, Nise tablet is restricted or discouraged in many guidelines and should only be used under strict medical supervision, for the shortest duration and at the lowest effective dose. It is not a first-line painkiller; medicines like paracetamol or ibuprofen are usually preferred initially. Nise is generally intended for adults; its use in children is limited or not recommended in many countries due to safety concerns. Common side effects may include nausea, vomiting, stomach pain, heartburn, diarrhea, dizziness, and headache. More serious but less common side effects include liver injury (hepatitis, jaundice), severe skin reactions, kidney problems, gastrointestinal bleeding or ulcers, and severe allergic reactions. Any sign of yellowing of the skin or eyes, dark urine, unusual fatigue, severe abdominal pain, vomiting blood, or black, tarry stools requires immediate medical attention and stopping the medicine. Nise tablet should be avoided in people with active liver disease, a history of liver damage related to nimesulide or other drugs, active peptic ulcer or gastrointestinal bleeding, severe kidney impairment, uncontrolled heart failure, or known allergy to nimesulide or other NSAIDs. It should also be avoided in late pregnancy and used with great caution, if at all, in early pregnancy and during breastfeeding, strictly on a doctor’s advice. Patients should inform their doctor about all other medicines they are taking, including over-the-counter painkillers, blood thinners, blood pressure medicines, and herbal supplements, because of the risk of interactions and additive side effects. Self-medication with Nise tablet, especially for long periods or at high doses, is unsafe. Always follow your doctor’s instructions and never exceed the prescribed duration of therapy.

Uses of NISE 100MG TABLET 15'S

  • Managing and treating fever effectively.
  • Providing relief from various types of pain and discomfort.

How NISE 100MG TABLET 15'S Works

  • NISE 100MG TABLET 15'S is a non-steroidal anti-inflammatory drug (NSAID) that provides relief from pain and inflammation. It functions by targeting the body's production of specific chemical messengers responsible for triggering pain and inflammation. When these chemical messengers are blocked, the sensations of pain are reduced, and swelling and redness associated with inflammation subside. This helps to alleviate discomfort and improve mobility in affected areas. NISE 100MG TABLET 15'S effectively reduces the production of prostaglandins, which are key contributors to inflammation. By inhibiting the cyclooxygenase (COX) enzymes, which are crucial for prostaglandin synthesis, this medication helps to manage conditions characterized by pain, swelling, and stiffness. Furthermore, its mechanism of action extends to reducing fever, making it a versatile option for various ailments.
  • NISE 100MG TABLET 15'S works by targeting the source of pain and inflammation, providing effective relief. Its mechanism focuses on inhibiting the production of prostaglandins, substances in the body that contribute to inflammation, pain, and fever. By blocking the cyclooxygenase (COX) enzymes responsible for prostaglandin synthesis, NISE 100MG TABLET 15'S reduces the levels of these inflammatory mediators. This action helps alleviate symptoms like pain, swelling, and redness. Moreover, by reducing prostaglandin production, NISE 100MG TABLET 15'S also helps to lower fever, making it beneficial in managing various conditions associated with pain, inflammation, and elevated body temperature.
  • The medication's impact on prostaglandin production is pivotal in managing inflammatory conditions. NISE 100MG TABLET 15'S interferes with the COX enzymes, thereby reducing the synthesis of prostaglandins and providing relief from associated symptoms. This targeted action makes it a suitable choice for addressing a range of conditions where pain and inflammation are primary concerns.

Side Effects of NISE 100MG TABLET 15'SArrow

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

  • Nausea
  • Diarrhea
  • Vomiting
  • Increased liver enzymes

Safety Advice for NISE 100MG TABLET 15'SArrow

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Stomach and Intestines

Risk of ulcers and bleeding

Like other NSAIDs, Nise tablet can cause irritation of the stomach lining, leading to gastritis, ulcers, or gastrointestinal bleeding.

Dosage of NISE 100MG TABLET 15'SArrow

  • For children:
  • The dosage of NISE 100MG TABLET 15'S for children is typically based on their body weight. It is important to follow the prescribed dose by a healthcare provider. The recommended dose is usually around 5 to 10 milligrams per kilogram of body weight per day, divided into two to three doses.
  • For adults:
  • For adults, the typical dosage of NISE 100MG TABLET 15'S is 100 to 200 milligrams twice daily. However, the exact dosage may vary depending on the specific condition being treated and individual factors. It is important to follow the instructions provided by a healthcare professional and not exceed the recommended dose or duration of treatment.

How to store NISE 100MG TABLET 15'S?Arrow

  • Keep NISE 100MG TAB 1X15 away from the reach of children and pets.
  • Store NISE 100MG TAB 1X15 at room temperature.

Benefits of NISE 100MG TABLET 15'SArrow

  • <b>Fever Treatment</b><br>NISE 100MG TABLET 15'S is effective in reducing high temperatures (fever). It functions by inhibiting the production of specific chemical messengers responsible for triggering fever. Your doctor might prescribe it alone or in conjunction with other medications to manage your fever effectively. Adhere to your doctor's instructions and take it consistently as directed for optimal results. This medication provides relief by targeting the root cause of the fever, helping you feel better and recover faster.
  • <b>Pain Relief</b><br>NISE 100MG TABLET 15'S serves as a reliable solution for alleviating various aches and pains. It acts by interfering with chemical signals in the brain that transmit pain sensations. It proves beneficial in relieving pain associated with headaches, migraines, nerve discomfort, toothaches, sore throats, menstrual discomfort, arthritis, and muscle soreness. When taken at the correct dosage, this medicine is widely used and rarely produces adverse effects. It's a trusted option for managing pain and improving your overall comfort.
  • To maximize the benefits, it's important to adhere to the prescribed dosage and duration. Avoid exceeding the recommended dose or prolonging the treatment unnecessarily, as this could lead to potential health risks. Generally, it's advisable to use the lowest effective dose for the shortest duration required to achieve pain relief. If your symptoms persist or worsen, consult your doctor for further evaluation and guidance.

How to use NISE 100MG TABLET 15'SArrow

  • Always take NISE 100MG TABLET 15'S exactly as your doctor has instructed. The prescribed dosage and duration of treatment are determined by your doctor, based on your specific medical condition and response to the medication. Ensure you follow these instructions carefully for optimal results.
  • Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet, as this can affect how the medication is absorbed and utilized by your body. The tablet is designed to release the medication in a controlled manner, and altering its form can disrupt this process.
  • It is generally recommended to take NISE 100MG TABLET 15'S with food. This can help to reduce the risk of stomach upset or other gastrointestinal side effects. If you experience any discomfort, try taking the tablet immediately after a meal or with a snack.
  • If you have any questions or concerns about how to take NISE 100MG TABLET 15'S, do not hesitate to ask your doctor or pharmacist for clarification. They can provide personalized guidance based on your individual needs.

FAQs

Is NISE 100MG TABLET 15'S an antibiotic?Arrow

NISE 100MG TABLET 15'S is not an antibiotic, it belongs to the class of medicines known as non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) which helps in relieving pain associated with various disease conditions.

Can I take NISE 100MG TABLET 15'S with paracetamol?Arrow

NISE 100MG TABLET 15'S and paracetamol belong to the same class of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. However, please consult your doctor before using the two medicines together.

Does NISE 100MG TABLET 15'S contain aspirin?Arrow

NISE 100MG TABLET 15'S is a non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug). It does not contain aspirin.

Is NISE 100MG TABLET 15'S safe?Arrow

NISE 100MG TABLET 15'S is safe to use if taken at prescribed dose and duration as advised by your doctor.

Can I take NISE 100MG TABLET 15'S for headache?Arrow

NISE 100MG TABLET 15'S can be taken for a headache only when advised by your doctor.

Does NISE 100MG TABLET 15'S make you drowsy (feeling sleepy)?Arrow

NISE 100MG TABLET 15'S does not make you feel drowsy at prescribed doses. However, an overdose of NISE 100MG TABLET 15'S can make you drowsy (feeling sleepy).

Does NISE 100MG TABLET 15'S contain sulphur?Arrow

No, NISE 100MG TABLET 15'S does not contain sulphur.

What does NISE 100MG TABLET 15'S treat or used for?Arrow

NISE 100MG TABLET 15'S is used to treat acute pain, painful osteoarthritis (degeneration of joints) and primary dysmenorrhea (painful menstruation) in adolescents and adults above 12 years old.

Can I take NISE 100MG TABLET 15'S with ibuprofen?Arrow

NISE 100MG TABLET 15'S can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, taking the two medicines together is not advisable as it may increase the potential for gastric ulceration and bleeding. Please consult your doctor before taking the two medicines together.

Can I take NISE 100MG TABLET 15'S with aspirin?Arrow

NISE 100MG TABLET 15'S can be taken with aspirin. No drug-drug interactions have been clinically observed between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

Is NISE 100MG TABLET 15'S safe?Arrow

Yes, NISE 100MG TABLET 15'S is safe if taken for prescribed duration in prescribed doses as advised by your doctor.

Is NISE 100MG TABLET 15'S banned?Arrow

No, NISE 100MG TABLET 15'S is not banned in India. However, as per the Ministry of Health and Family Welfare, NISE 100MG TABLET 15'S is banned for children under 12 years of age

Is NISE 100MG TABLET 15'S safe during breastfeeding?Arrow

It is not known if NISE 100MG TABLET 15'S is secreted in milk. So, any medicines containing NISE 100MG TABLET 15'S are not to be used during breastfeeding.

Is NISE 100MG TABLET 15'S safe in pregnancy?Arrow

No, NISE 100MG TABLET 15'S is not safe to be used in pregnancy especially in the last three months. There have been reports of kidney failure in newborn babies if the mother was taking NISE 100MG TABLET 15'S in the late stage of pregnancy. Consult your doctor before taking any medicine during pregnancy.

Is NISE 100MG TABLET 15'S safe in asthma?Arrow

NISE 100MG TABLET 15'S is reported to be safe in patients with asthma if taken as advised by your doctor. However, always share your disease history with the doctor in case you have asthma and you are advised to take other medicines.

What is Nise tablet used for?Arrow

Nise tablet contains nimesulide, an NSAID used for short-term relief of pain and inflammation. Doctors may prescribe it for acute musculoskeletal pain, dental pain, painful periods (dysmenorrhea), and sometimes for pain related to osteoarthritis or soft tissue injuries when other safer painkillers are not suitable or effective. It is not intended for long-term use and should only be taken under medical supervision.

How does Nise tablet work in the body?Arrow

Nise tablet works by inhibiting cyclo-oxygenase (COX) enzymes and reducing the formation of prostaglandins, which are chemicals that promote pain, inflammation, and fever. By lowering prostaglandin levels, Nise helps decrease pain and swelling. It may also have some additional actions on inflammatory mediators and free radicals, but its main effect is through prostaglandin inhibition, similar to other NSAIDs.

Is Nise tablet safe for the liver?Arrow

Nise tablet can be harmful to the liver in some people. Nimesulide has been associated with liver injury ranging from mild elevation of liver enzymes to severe hepatitis and, rarely, liver failure. It should not be used in patients with existing liver disease or a history of liver damage related to nimesulide or other drugs. Treatment should be as short as possible, and any symptoms such as yellowing of the skin or eyes, dark urine, severe fatigue, nausea, or abdominal pain require immediate medical attention and stopping the medicine. Regular monitoring may be advised if used even for a short period in higher-risk patients.

Can I take Nise tablet if I have kidney problems?Arrow

Nise tablet should be used with great caution in people with kidney problems and is generally avoided in those with moderate to severe kidney impairment. NSAIDs can reduce blood flow to the kidneys and may worsen kidney function, especially in patients who are dehydrated, elderly, or taking other medicines that affect the kidneys. If you have any kidney disease, you must inform your doctor before taking Nise. Your doctor may choose an alternative painkiller or use the lowest effective dose for the shortest time with close monitoring.

Is Nise tablet safe during pregnancy?Arrow

Nise tablet is not considered safe during pregnancy, especially in the third trimester. Like other NSAIDs, nimesulide can affect the fetal heart and blood circulation (ductus arteriosus), reduce amniotic fluid, and increase the risk of complications during delivery. In the first and second trimesters, it should only be used if clearly needed and if the potential benefit outweighs the risks, and even then, for the shortest possible duration. Pregnant women or those planning pregnancy should consult their doctor for safer alternatives such as paracetamol.

Can I take Nise tablet while breastfeeding?Arrow

Nise tablet is generally not recommended during breastfeeding. Nimesulide may pass into breast milk, and there is limited safety data for infants. Because of the potential risk of serious side effects, including liver toxicity, doctors usually advise avoiding Nise while breastfeeding. If pain relief is needed, your doctor will typically recommend safer alternatives. Never start Nise on your own while nursing without explicit medical advice.

Is it safe to drive or operate machines after taking Nise tablet?Arrow

Nise tablet can cause side effects such as dizziness, drowsiness, and visual disturbances in some people. If you experience any of these symptoms after taking Nise, you should avoid driving, operating heavy machinery, or performing tasks that require full alertness. If you feel normal and have no such symptoms, driving may be acceptable, but you should still be cautious, especially when taking the medicine for the first time or in combination with other drugs that can cause drowsiness.

Can I drink alcohol while taking Nise tablet?Arrow

Alcohol should be avoided while taking Nise tablet. Both alcohol and nimesulide can irritate the stomach lining and increase the risk of gastrointestinal bleeding and ulcers. In addition, both substances can stress the liver, raising the risk of liver damage. Combining them may significantly increase the chance of serious side effects. If you have consumed alcohol, inform your doctor before taking Nise, and do not drink during the course of treatment.

What should I do if I am allergic to painkillers like ibuprofen or aspirin?Arrow

If you have a history of allergy or severe reactions to NSAIDs such as ibuprofen, aspirin, or diclofenac, you should inform your doctor before taking Nise tablet. Symptoms like wheezing, shortness of breath, chest tightness, swelling of the face or throat, severe skin rash, or a history of aspirin-sensitive asthma are warning signs. People with such histories may also react to nimesulide. In that case, Nise is usually avoided, and your doctor will choose a different class of pain reliever that is safer for you.

Can I use Nise tablet for long-term pain conditions like arthritis?Arrow

Nise tablet is not recommended for long-term or chronic use, even in conditions like arthritis. Due to its potential for serious side effects, particularly liver toxicity and gastrointestinal complications, it is intended only for short-term management of acute pain episodes. For chronic conditions, doctors usually prefer other medicines with a better-established long-term safety profile, along with non-drug measures such as physiotherapy and lifestyle changes. Never continue Nise beyond the duration advised by your doctor.

What should I tell my doctor before starting Nise tablet?Arrow

Before starting Nise tablet, inform your doctor about any history of liver disease, kidney disease, stomach ulcers or bleeding, heart disease, high blood pressure, asthma, bleeding disorders, or severe allergies to any medicines. Also share all medicines you are currently taking, including over-the-counter painkillers, blood thinners, blood pressure drugs, diuretics, antidepressants, and herbal or dietary supplements. Mention if you are pregnant, planning pregnancy, or breastfeeding. This information helps your doctor decide whether Nise is appropriate for you and how to use it as safely as possible.

References

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ScienceDirect. Nimesulide. (online) Available from:

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PubChem. Nimesulide. (online) Available from:

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Nimesulide. [2004]. (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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Nimesulide [Summary of Product Characteristics]. Brescia, Italy: Magis Farmaceutici Srl; 2022. (online) Available from:

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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