NUCOXIA MR 8MG TABLET 10'S

How NUCOXIA MR 8MG TABLET 10'S Works

• NUCOXIA MR 8MG TABLET 10'S is a combination medication designed to alleviate pain and muscle spasms. It contains Etoricoxib and Thiocolchicoside, each contributing uniquely to its therapeutic effects. Etoricoxib, a highly selective COX-2 inhibitor, targets pain and inflammation at their source. Cyclooxygenase-2 (COX-2) is an enzyme responsible for producing prostaglandins, chemicals that promote pain, inflammation, and fever. By selectively inhibiting COX-2, Etoricoxib reduces the production of these prostaglandins, thereby diminishing pain and inflammation, particularly in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gout.
• Thiocolchicoside, the other key ingredient, functions as a muscle relaxant. It works primarily within the central nervous system (CNS) to reduce muscle spasms and associated pain. Its mechanism of action involves acting as a GABA-mimetic agent and a glycine receptor agonist. GABA (gamma-aminobutyric acid) is an inhibitory neurotransmitter that helps to calm nerve activity, while glycine receptors also play a role in inhibiting neuronal excitability. By enhancing these inhibitory pathways, Thiocolchicoside helps to reduce excessive muscle tone and spasms, leading to muscle relaxation and pain relief. It is often used to treat muscle spasms resulting from various conditions, such as back pain, neck pain, and other musculoskeletal disorders.
• The combination of Etoricoxib and Thiocolchicoside in NUCOXIA MR 8MG TABLET 10'S provides a synergistic effect, addressing both the inflammatory component of pain and the muscular component. Etoricoxib reduces inflammation and pain signaling, while Thiocolchicoside relaxes the muscles and reduces spasms. This dual action can lead to more effective pain relief and improved mobility for patients suffering from musculoskeletal conditions. This medicine should be taken as prescribed by the physician, and one should consult in case of any side effects.

Like all medicines, NUCOXIA MR 8MG TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Stomach pain * Heartburn * Nausea * Diarrhea * Indigestion * Increased blood pressure * Swelling in the legs or ankles * Headache * Dizziness * Flu-like symptoms **Uncommon Side Effects (may affect up to 1 in 100 people):** * Gastritis (inflammation of the stomach lining) * Stomach ulcer * Irritable bowel syndrome * Bloating * Acid reflux * Changes in bowel habits * Anxiety * Depression * Insomnia * Tingling or numbness * Taste disturbance * Blurred vision * Ringing in the ears (tinnitus) * Vertigo * Irregular heartbeat * Chest pain * Cough * Shortness of breath * Runny nose * Skin rash * Itching * Muscle cramps * Muscle pain * Fatigue * Weakness * Changes in liver function tests * Changes in kidney function tests **Rare Side Effects (may affect up to 1 in 1,000 people):** * Stomach bleeding * Liver problems * Kidney failure * Severe allergic reactions (anaphylaxis) * Confusion * Hallucinations **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) **Side effects with unknown frequency:** * Heart failure * Stroke This is not an exhaustive list. If you experience any other unusual symptoms, consult your doctor or pharmacist.

• If you miss a dose of Nucoxia MR 8mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep NUCOXIA MR 8MG TAB 1X10 away from the reach of children and pets.
• Store NUCOXIA MR 8MG TAB 1X10 at room temperature.

• Take NUCOXIA MR 8MG TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration, as this can increase the risk of side effects. It's crucial to adhere to your doctor's instructions for optimal results and safety. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Avoid doubling up on doses to compensate for a missed one.
• NUCOXIA MR 8MG TABLET 10'S is often prescribed to relieve pain and inflammation associated with musculoskeletal conditions. Common uses include managing pain from osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also effective for relieving muscle spasms and associated discomfort. The medicine works by reducing the production of substances in the body that cause pain and inflammation. Ensure you understand the specific condition it is treating for you and consult your doctor if you have any questions about its use.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting NUCOXIA MR 8MG TABLET 10'S. This includes over-the-counter drugs, as interactions can occur. Certain medications, such as blood thinners, other NSAIDs, or some antidepressants, can interact with NUCOXIA MR, potentially increasing the risk of bleeding or other adverse effects. Your doctor needs a complete list of your medications to ensure safe and effective treatment.
• Be aware of potential side effects while taking NUCOXIA MR 8MG TABLET 10'S. Common side effects may include stomach upset, nausea, heartburn, diarrhea, or constipation. More serious side effects can include stomach ulcers, bleeding, liver problems, kidney problems, and allergic reactions. Contact your doctor immediately if you experience severe abdominal pain, black or bloody stools, persistent nausea, yellowing of the skin or eyes, difficulty breathing, or swelling of the face, lips, or tongue. Regular monitoring by your doctor can help detect and manage any potential issues early.
• Lifestyle modifications can complement the effects of NUCOXIA MR 8MG TABLET 10'S and improve your overall well-being. Maintaining a healthy weight can reduce stress on joints and muscles. Regular, gentle exercise, such as walking or swimming, can improve mobility and reduce pain. Applying heat or cold packs to affected areas may also provide relief. Ensure you have a balanced diet rich in anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids. Consult your doctor or a physical therapist for personalized advice on lifestyle changes that are appropriate for your condition.

• NUCOXIA MR 8MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of this medication.