NUPARP 200 TABLET 60'S
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NUPARP 200 TABLET 60'S
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NUPARP 200 TABLET 60'S

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NUPARP 200 TABLET 60'S

By ZYDUS LIFESCIENCES LIMITED

MRP

41500

₹26500

36.14 % OFF

₹441.67 Only /

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10

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Composition

Product DetailsArrow

About NUPARP 200 TABLET 60'S

  • NUPARP 200 TABLET 60'S contains rucaparib as its active ingredient. Rucaparib belongs to a class of medications known as PARP (poly ADP-ribose polymerase) inhibitors and functions as an anti-cancer medicine. This medication is prescribed to sustain the therapeutic effects of prior treatments for specific types of recurrent ovarian cancer, fallopian tube cancer (which transports eggs from the ovaries to the uterus), and primary peritoneal cancer (cancer of the tissue lining the abdomen) in adult patients who have previously shown a complete or partial response to other chemotherapy regimens.
  • It is also indicated for treating certain cancers in individuals with specific BRCA gene mutations who have already undergone at least two lines of chemotherapy. Additionally, it serves as maintenance therapy immediately following chemotherapy that has successfully reduced the tumor size. Before taking NUPARP 200 TABLET 60'S, inform your doctor if you are allergic to rucaparib or any of the inactive ingredients in the tablet. This medicine can potentially lower blood cell counts, so regular blood tests will be required before starting and throughout the treatment, as advised by your healthcare provider. Contact your doctor immediately if you develop any symptoms.
  • Inform your doctor if you experience nausea, vomiting, diarrhea, or abdominal pain during treatment, as this medication can affect your digestive system. NUPARP 200 TABLET 60'S is not intended for use in children under the age of 18. If you are pregnant, breastfeeding, suspect you may be pregnant, or are planning to become pregnant, notify your doctor before starting treatment with this medication. Women of childbearing potential must use effective contraception while taking this medication.
  • Regular monitoring and open communication with your healthcare team are crucial for managing potential side effects and ensuring the safe and effective use of NUPARP 200 TABLET 60'S. Always follow your doctor's instructions carefully and report any concerns promptly. This approach will help to optimize your treatment outcomes and overall well-being throughout the duration of your therapy.

Uses of NUPARP 200 TABLET 60'S

  • Ovarian cancer: This cancer starts in the ovaries, which are part of the female reproductive system and produce eggs.
  • Fallopian tube cancer: This cancer develops in the fallopian tubes, which carry eggs from the ovaries to the uterus.
  • Primary peritoneal cancer: This is a rare cancer that develops in the lining of the abdomen, called the peritoneum.
  • Prostate cancer: NUPARP 200 TABLET 60'S is used to treat prostate cancer, which affects the prostate gland in men.

Side Effects of NUPARP 200 TABLET 60'SArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. With NUPARP 200 TABLET 60'S, common and serious side effects can occur.

  • Rash
  • Constipation
  • Decrease in appetite
  • Diarrhea, indigestion
  • Nausea, vomiting
  • Changes in the blood count
  • Shortness of breath
  • Tiredness
  • Severe anemia
  • Hypersensitivity reactions
  • Sepsis (blood infection)
  • Pneumonia

Safety Advice for NUPARP 200 TABLET 60'SArrow

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Pregnancy

UNSAFE

Do not take NUPARP 200 TABLET 60'S if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 6 months after the last dose.

Dosage of NUPARP 200 TABLET 60'SArrow

  • NUPARP 200 TABLET 60'S is an orally administered prescription medication. Its dosage and duration are determined by your physician, factoring in the specific disease being treated and other individual patient characteristics. Adhere strictly to your doctor's instructions regarding its use.
  • For optimal results, take NUPARP 200 TABLET 60'S at the same time each day, irrespective of meals. The tablet should be swallowed whole with water; do not crush, chew, or break it. Consistent timing helps maintain a steady level of medication in your system.
  • If you miss a dose of NUPARP 200 TABLET 60'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double your dose to make up for a missed one. If you have any concerns about missed doses, consult your healthcare provider.
  • It is crucial to complete the entire course of treatment as prescribed by your doctor, even if you start feeling better. Stopping the medication prematurely could lead to a recurrence of the infection or the development of resistance. Regular follow-up appointments with your doctor are essential to monitor your progress and address any concerns you may have.

How to store NUPARP 200 TABLET 60'S?Arrow

  • Keep NUPARP 200MG TAB 1X60 away from the reach of children and pets.
  • Store NUPARP 200MG TAB 1X60 at room temperature.

Benefits of NUPARP 200 TABLET 60'SArrow

  • NUPARP 200 TABLET 60'S belongs to a class of medications known as PARP inhibitors. It functions by targeting and inhibiting poly (ADP-ribose) polymerase (PARP) enzymes, specifically PARP-1, PARP-2, and PARP-3. These enzymes are crucial for DNA repair mechanisms within cells. By blocking PARP's activity, NUPARP 200 TABLET 60'S disrupts the ability of cancer cells to repair their damaged DNA. This ultimately leads to the accumulation of DNA damage, which triggers cell death in cancer cells.
  • NUPARP 200 TABLET 60'S is particularly effective in cancers with deficiencies in DNA repair pathways, such as those with BRCA mutations. These mutations impair the cells' ability to fix damaged DNA, making them more susceptible to the effects of PARP inhibition. When cancer cells can no longer repair their DNA, they become unstable and undergo apoptosis, a process of programmed cell death.
  • In essence, NUPARP 200 TABLET 60'S acts as a targeted therapy that exploits a vulnerability in cancer cells, leading to their destruction. The precise mechanism of action is to prevent DNA repair, thus the cancerous cells self destructs and does not grow. This inhibitory action is very critical in treatment. It is prescribed to patients with certain types of cancers and should be taken as directed by healthcare professional.

How to use NUPARP 200 TABLET 60'SArrow

  • NUPARP 200 TABLET 60'S is a prescription medication that is taken orally. Your doctor will determine the appropriate dosage and duration of treatment, taking into account your specific medical condition, its severity, and other relevant factors. It's crucial to strictly adhere to your doctor's instructions when taking this medicine.
  • For optimal results, take NUPARP 200 TABLET 60'S at the same time each day. You can take it with or without food, as per your doctor's recommendation. Consistency in timing helps maintain a steady level of the medication in your system.
  • It's important to swallow the tablet whole with a glass of water. Avoid breaking, chewing, crushing, or otherwise altering the tablet, as this can affect how the medication is absorbed and works in your body. If you have any difficulties swallowing tablets, discuss this with your doctor or pharmacist, who can provide alternative solutions.
  • If you miss a dose of NUPARP 200 TABLET 60'S, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

FAQs

Is it safe to administer NUPARP 200 TABLET 60'S in patients with kidney disease?Arrow

Yes, it is safe to administer NUPARP 200 TABLET 60'S in patients with kidney disease. No dose adjustments are necessary. Inform your physician if you have kidney disorders before initiating the therapy.

What should I tell my healthcare provider before taking NUPARP 200 TABLET 60'S?Arrow

Inform your physician about all your past medical and medication history, including over-the-counter medicines, nutritional or vitamin supplements that you are taking.

I am a male patient. Do I have to use contraception during the treatment with this medicine?Arrow

Yes, male patient with female partner of reproductive potential should use effective contraception during the treatment and for 3 months after the last dose of NUPARP 200 TABLET 60'S.

Do I have to wear sunscreen while taking NUPARP 200 TABLET 60'S?Arrow

Yes, this medicine makes your skin more sensitive to sunlight. Wear sunscreen during the treatment after consulting your doctor.

How long do I have to take NUPARP 200 TABLET 60'S?Arrow

The duration of your treatment depends on your disease condition and severity. Your doctor will decide your dose, and duration of your treatment.

Does NUPARP 200 TABLET 60'S interact with other drugs?Arrow

There are no known interactions of NUPARP 200 TABLET 60'S with other drugs.

What precautions should I take during treatment with NUPARP 200 TABLET 60'S?Arrow

You may get sunburn easily during treatment with NUPARP 200 TABLET 60'S. Keep out of direct sunlight and wear protective clothing that covers your head, arms, and legs. Use sunscreen and lip balm with a sun protection factor (SPF) after consulting your doctor. If you vomit after taking the medicine, do not take an extra dose. Take your next dose at the regular time. Do not stop taking this medicine without talking to your doctor. Your doctor may do lab tests to check the therapy's effectiveness or monitor the unwanted side effects.

Which molecule/combination is used for making NUPARP 200 TABLET 60'S?Arrow

RUCAPARIB is molecule/combination used for making NUPARP 200 TABLET 60'S.

For what conditions is NUPARP 200 TABLET 60'S prescribed?Arrow

NUPARP 200 TABLET 60'S is prescribed for Oncology.

Does NUPARP 200 TABLET 60'S help in treating cancer?Arrow

NUPARP 200 TABLET 60'S is used to treat certain types of cancer.

References

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Rubraca 250mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk.

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HIGHLIGHTS OF PRESCRIBING INFORMATION - Rucaparib.

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Shirley M. Rucaparib: A Review in Ovarian Cancer. Targeted Oncology. [2019 Apr 1];14(2):237–46.

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Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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