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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Most side effects are temporary and resolve as your body adapts to the medication. However, if any side effects persist or cause concern, it's important to consult your doctor.

Other Precautions
Tendons, nervous system, and cardiac monitoringFluoroquinolones, including ofloxacin, are associated with an increased risk of tendonitis and tendon rupture, particularly in older adults, patients on systemic corticosteroids, and those with kidney, heart, or lung transplants. Any tendon pain, swelling, or difficulty moving a limb should prompt immediate discontinuation and medical review.
Yes, the use of OF 200MG TABLET 10'S can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
No, do not stop taking OF 200MG TABLET 10'S and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Yes, use of OF 200MG TABLET 10'S is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take OF 200MG TABLET 10'S. Inform your doctor if you feel any kind of muscle pain while using this medicine.
OF 200 tablet, containing ofloxacin 200 mg, is used to treat a range of bacterial infections, including certain urinary tract infections, respiratory tract infections (such as bronchitis and some types of pneumonia), skin and soft tissue infections, and specific gastrointestinal infections like infectious diarrhoea caused by susceptible bacteria. It is prescribed only when the treating clinician believes that the likely causative organisms are sensitive to ofloxacin.
OF 200 tablet works by inhibiting bacterial enzymes called DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication, repair, and transcription. By blocking these enzymes, ofloxacin prevents bacteria from multiplying and repairing themselves, leading to bacterial cell death and resolution of the infection, provided the organism is susceptible and the full prescribed course is completed.
Symptomatic improvement with OF 200 tablet often begins within 48 to 72 hours of starting therapy, although this can vary depending on the site and severity of infection, the patient’s overall health, and bacterial susceptibility. Fever and pain may gradually reduce, but it is important to continue taking the medicine for the entire prescribed duration even if symptoms improve early, to ensure complete eradication of the infection and to reduce the risk of resistance or relapse.
No. OF 200 tablet is an antibiotic effective only against certain bacterial infections. It has no activity against viruses and should not be used for viral illnesses such as the common cold, seasonal flu, or most sore throats. Using antibiotics inappropriately for viral infections offers no benefit and contributes to the development of antibiotic resistance, making future bacterial infections harder to treat.
Common side effects of OF 200 tablet include nausea, vomiting, abdominal pain, diarrhoea, indigestion, headache, dizziness, and trouble sleeping. Some people may experience a metallic taste in the mouth or mild skin rash. These effects are usually mild and transient. However, if symptoms are persistent, severe, or associated with signs of dehydration or allergic reaction, medical advice should be sought promptly.
Yes. Although uncommon, OF 200 tablet can cause serious adverse effects, including tendonitis and tendon rupture (especially in the Achilles tendon), peripheral neuropathy (numbness, tingling, burning sensations), central nervous system effects such as confusion, agitation, hallucinations, or seizures, severe allergic reactions, and disturbances in heart rhythm (QT prolongation) in predisposed individuals. It can also cause severe, persistent diarrhoea due to Clostridioides difficile infection. Any sudden tendon pain, muscle weakness, severe diarrhoea, chest palpitations, or neurological or psychiatric symptoms require immediate medical evaluation and discontinuation of the drug under medical supervision.
Products containing aluminium or magnesium (such as many antacids), as well as supplements or preparations containing iron, zinc, or calcium in high amounts, can reduce the absorption of ofloxacin if taken at the same time. While normal dietary intake of milk and dairy is usually acceptable, large amounts of calcium‑fortified products or mineral supplements should not be taken simultaneously with OF 200 tablet. Your doctor or pharmacist may advise separating such products and the tablet by several hours to maintain adequate antibiotic levels.
If you miss a dose of OF 200 tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. If the next dose is near, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or extra doses to make up for a missed one, as this increases the risk of side effects without improving effectiveness. If you frequently forget doses, discuss strategies for adherence with your healthcare provider.
Use of OF 200 tablet during pregnancy is generally avoided unless the potential benefit clearly outweighs the potential risk, as fluoroquinolones have raised concerns in animal studies regarding effects on developing cartilage. During breastfeeding, ofloxacin can pass into breast milk, and there is theoretical risk to the infant’s developing joints and gut flora. Decisions about use in pregnancy or lactation must be made by a doctor after carefully weighing alternatives, and in some cases an alternative antibiotic with a more established safety profile may be preferred.
You should stop taking OF 200 tablet and seek urgent medical care if you develop sudden tendon pain, swelling, or difficulty moving a joint; severe or bloody diarrhoea; signs of an allergic reaction such as widespread rash, itching, swelling of the face, lips, or throat, or difficulty breathing; severe dizziness or fainting; new or worsening confusion, agitation, hallucinations, or seizures; or chest pain and palpitations. These may indicate serious adverse reactions that require immediate assessment and alternative treatment.
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J B CHEMICALS AND PHARMACEUTICALS LTD
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India
Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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