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OFLOTAS IV INJECTION 100 ML

Name: OFLOTAS IV INJECTION 100 ML
Brand: INTAS PHARMACEUTICALS LIMITED
Price: 23 INR
Availability: Discontinued

OFLOTAS IV INJECTION 100 ML

By INTAS PHARMACEUTICALS LIMITED

MRP

₹

118

₹23

80.51 % OFF

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Composition

OFLOXACIN 200 MG / 100ML

Product Details

About OFLOTAS IV INJECTION 100 ML

OFLOTAS IV INJECTION 100 ML is a potent intravenous antibiotic solution designed for combating a wide range of bacterial infections. It contains Ofloxacin as its active ingredient, a fluoroquinolone antibiotic known for its broad-spectrum activity. This formulation is specifically intended for use in hospital settings where controlled administration and monitoring are feasible.
Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for bacterial DNA replication, transcription, repair, and recombination. By blocking these enzymes, Ofloxacin effectively halts bacterial growth and proliferation, leading to the eradication of the infection. The intravenous route ensures rapid and complete bioavailability, making it particularly useful in severe or complicated infections where oral administration is not suitable or effective.
OFLOTAS IV INJECTION is indicated for the treatment of various infections, including but not limited to respiratory tract infections such as pneumonia and bronchitis, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. Its efficacy extends to infections caused by both Gram-positive and Gram-negative bacteria, making it a versatile option in empirical therapy while awaiting culture results.
The 100 ML presentation allows for convenient and accurate dosing, minimizing the risk of medication errors. Each vial is carefully manufactured under stringent quality control standards to ensure sterility and stability, safeguarding patient safety. It is essential that OFLOTAS IV INJECTION is administered by qualified healthcare professionals who can monitor the patient for potential adverse reactions such as nausea, vomiting, diarrhea, or more serious events like allergic reactions or tendon damage.
Prior to administration, healthcare providers should carefully assess the patient's medical history, including any known allergies or pre-existing conditions, to minimize the risk of complications. Dosage adjustments may be necessary in patients with impaired renal function. OFLOTAS IV INJECTION should be used with caution in elderly patients and children due to the potential for adverse effects on cartilage development. This medication is a valuable tool in the fight against serious bacterial infections when used appropriately and under strict medical supervision.

Uses of OFLOTAS IV INJECTION 100 ML

Treatment of Pneumonia
Treatment of Urinary Tract Infections (UTIs)
Treatment of Skin and Soft Tissue Infections
Treatment of Intra-abdominal Infections
Treatment of Bone and Joint Infections
Treatment of Septicemia (Blood Infection)
Treatment of Respiratory Tract Infections
Treatment of Complicated Surgical Infections
Treatment of Pelvic Inflammatory Disease (PID)
Treatment of Prostatitis (Prostate Gland Infection)
Treatment of Anthrax (Post-Exposure Prophylaxis)

How OFLOTAS IV INJECTION 100 ML Works

OFLOTAS IV INJECTION 100 ML contains Ofloxacin, a synthetic broad-spectrum antibacterial agent belonging to the fluoroquinolone class. It is designed to combat a wide array of bacterial infections by targeting essential bacterial enzymes, namely DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA replication, transcription, repair, and recombination. By inhibiting these enzymes, Ofloxacin effectively disrupts bacterial DNA metabolism, leading to bacterial cell death.
Specifically, Ofloxacin binds to DNA gyrase and topoisomerase IV, preventing them from performing their essential functions. DNA gyrase is responsible for supercoiling DNA, a process necessary for packaging the long DNA strands into the bacterial cell. Topoisomerase IV, on the other hand, plays a vital role in separating newly replicated DNA strands during cell division. When Ofloxacin inhibits these enzymes, the bacterial DNA becomes unstable and fragmented, ultimately leading to the cessation of bacterial growth and reproduction.
The broad-spectrum activity of Ofloxacin allows it to be effective against a variety of Gram-positive and Gram-negative bacteria, as well as some atypical bacteria. This makes it a valuable tool in treating a range of infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. The intravenous administration of OFLOTAS IV INJECTION 100 ML ensures rapid and complete bioavailability of the drug, allowing it to reach the site of infection quickly and efficiently. The mechanism of action of Ofloxacin provides a targeted approach to eradicating bacterial infections while minimizing the impact on host cells, contributing to its efficacy and safety profile.
In simpler terms, imagine bacterial DNA as a tangled ball of yarn. Enzymes like DNA gyrase are like tiny machines that keep the yarn organized and allow the bacteria to grow and multiply. Ofloxacin acts like a wrench thrown into these machines, causing the yarn to become even more tangled and ultimately breaking the machine down. This prevents the bacteria from replicating, leading to their demise and clearing the infection. Because it's given intravenously, the medication quickly gets into the bloodstream and starts working to fight the bacteria throughout the body.

Side Effects of OFLOTAS IV INJECTION 100 ML

Diarrhea
Nausea
vomiting
Headache
Dizziness
Insomnia
Skin rash and itching
Abdominal pain and discomfort
Joint and muscle pain
Photosensitivity or increased sensitivity to sunlight
Changes in taste and smell

Safety Advice for OFLOTAS IV INJECTION 100 ML

Allergies

Do not use OFLOTAS IV Injection 100 ml if you are allergic to it.

Dosage of OFLOTAS IV INJECTION 100 ML

The recommended dosage of OFLOTAS IV INJECTION 100 ML varies significantly depending on the type and severity of the infection being treated, as well as the patient's overall health, renal function, and other concurrent medications. It is crucial to adhere strictly to the dosage prescribed by your healthcare provider. A typical adult dosage may range from 200 to 400 mg administered intravenously over a period of 30 to 60 minutes, every 12 hours. For more severe infections, the dosage might be adjusted upwards, but this should only be done under the direct supervision of a physician.
The duration of treatment also depends on the infection's nature and the patient's response to therapy. Treatment courses commonly last from 7 to 14 days, but in some cases, longer durations may be necessary. It is essential to complete the entire course of treatment, even if symptoms improve before the course is finished, to ensure complete eradication of the infection and prevent the development of antibiotic resistance. Premature discontinuation of the injection could result in a relapse of the infection or the emergence of resistant bacteria.
Patients with impaired renal function may require dosage adjustments to prevent the accumulation of the drug in the body and reduce the risk of adverse effects. Your doctor will assess your kidney function and adjust the dosage accordingly. It's imperative to inform your healthcare provider about any existing kidney problems before starting treatment with OFLOTAS IV INJECTION 100 ML. Similarly, it is important to discuss all other medications you are currently taking, as drug interactions can occur. Take 'OFLOTAS IV INJECTION 100 ML' only as per the prescription by your physician only.

What if I miss my dose of OFLOTAS IV INJECTION 100 ML?

If you miss a dose of Oflotas IV Injection, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
Contact your doctor immediately if you miss a dose or more.

How to store OFLOTAS IV INJECTION 100 ML?

Keep OFLOTAS IV INJ 100ML away from the reach of children and pets.
Store OFLOTAS IV INJ 100ML at room temperature.

Benefits of OFLOTAS IV INJECTION 100 ML

Oflotas IV Injection 100 ml is a potent broad-spectrum antibiotic belonging to the fluoroquinolone class, meticulously formulated for intravenous administration to combat a wide array of bacterial infections. Its efficacy stems from its ability to inhibit bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, and repair. By disrupting these processes, Oflotas effectively halts bacterial growth and eliminates the infection.
One of the primary benefits of Oflotas IV Injection lies in its ability to treat severe and complicated infections. It is particularly useful when oral medication is not feasible, or when a rapid and high concentration of the antibiotic is required in the bloodstream. This makes it an invaluable asset in hospital settings and for patients who are unable to take oral medication due to vomiting, difficulty swallowing, or impaired absorption.
Oflotas IV Injection is highly effective against a diverse range of bacterial pathogens, including Gram-positive and Gram-negative bacteria. This broad-spectrum activity makes it suitable for treating various infections such as respiratory tract infections (including pneumonia and bronchitis), urinary tract infections (UTIs), skin and soft tissue infections, bone and joint infections, intra-abdominal infections, and gynecological infections. Its versatility ensures comprehensive coverage against a wide range of bacterial threats.
In respiratory tract infections, Oflotas IV Injection is particularly effective in treating severe pneumonia, including hospital-acquired pneumonia. It helps to eradicate the bacteria causing the infection, reduce inflammation, and alleviate symptoms such as cough, fever, and shortness of breath, promoting faster recovery and improved respiratory function.
For urinary tract infections (UTIs), including complicated UTIs and pyelonephritis (kidney infection), Oflotas IV Injection provides rapid relief by targeting the bacteria responsible for the infection. It helps to reduce symptoms such as frequent urination, burning sensation during urination, and abdominal pain, while preventing the infection from spreading to the kidneys and causing more severe complications.
In skin and soft tissue infections, such as cellulitis, abscesses, and wound infections, Oflotas IV Injection helps to control the infection, prevent its spread, and promote wound healing. It is especially useful in cases where the infection is deep-seated or resistant to other antibiotics. By eradicating the bacteria and reducing inflammation, Oflotas IV Injection facilitates faster recovery and minimizes the risk of complications.
Oflotas IV Injection is also valuable in treating bone and joint infections (osteomyelitis and septic arthritis) by penetrating the infected tissues and eradicating the bacteria. It helps to reduce pain, swelling, and stiffness in the affected joints, while preventing long-term damage to the bones and joints. Its ability to reach these difficult-to-access areas makes it a critical tool in managing these severe infections.
Furthermore, Oflotas IV Injection plays a crucial role in treating intra-abdominal infections such as peritonitis and abscesses, which can be life-threatening. By controlling the infection and preventing its spread to other organs, it helps to stabilize the patient's condition and improve their chances of survival. In gynecological infections, such as pelvic inflammatory disease (PID), Oflotas IV Injection helps to eradicate the bacteria, reduce inflammation, and prevent long-term complications such as infertility.
Another significant advantage of Oflotas IV Injection is its ease of administration. As an intravenous formulation, it allows for direct delivery into the bloodstream, ensuring rapid and complete absorption. This is particularly important in critically ill patients where time is of the essence. The intravenous route also bypasses the gastrointestinal tract, minimizing the risk of drug interactions and ensuring consistent drug levels in the body.
Overall, Oflotas IV Injection 100 ml is a valuable asset in the fight against severe bacterial infections. Its broad-spectrum activity, rapid onset of action, and ease of administration make it an indispensable tool for healthcare professionals in managing a wide range of infectious diseases, ultimately improving patient outcomes and saving lives.

How to use OFLOTAS IV INJECTION 100 ML

OFLOTAS IV INJECTION 100 ML is administered intravenously, meaning it's given directly into a vein. This should always be done by a qualified healthcare professional in a hospital or clinical setting. Self-administration is strictly prohibited.
The dosage and duration of treatment with OFLOTAS IV INJECTION are determined by your doctor based on the type and severity of your infection, your kidney function, and your overall health. It's crucial to follow your doctor's instructions precisely. Never adjust the dose or stop the treatment prematurely, even if you start feeling better, as this can lead to antibiotic resistance or recurrence of the infection.
Before the injection, your doctor or nurse will assess your condition and confirm if you are allergic to any medications, especially quinolones. They will also check your medical history for any pre-existing conditions like heart problems, diabetes, or nervous system disorders, which may affect the use of OFLOTAS IV.
The injection is usually given slowly over a period of 60 minutes to minimize the risk of side effects such as dizziness, nausea, or irritation at the injection site. During the infusion, you will be closely monitored for any signs of adverse reactions, such as rash, itching, swelling, or difficulty breathing. Inform your healthcare provider immediately if you experience any unusual symptoms.
Maintain adequate hydration during the course of treatment. Drink plenty of fluids to help flush the medication from your system and prevent kidney problems. Avoid excessive exposure to sunlight or UV radiation, as OFLOTAS IV can increase your sensitivity to the sun. Use sunscreen and wear protective clothing when outdoors.
If you are taking other medications, including over-the-counter drugs and herbal supplements, inform your doctor. OFLOTAS IV can interact with certain medications, affecting their effectiveness or increasing the risk of side effects. Some medications may need to be adjusted or avoided altogether during treatment with OFLOTAS IV. Continue taking OFLOTAS IV INJECTION for the full prescribed length of time, even if your symptoms improve after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.
In case of any missed dose, consult your doctor immediately to seek advice on how to proceed. Do not self-adjust the dosage or timing. Proper adherence to the prescribed regimen is crucial for the successful treatment of the infection. Seek immediate medical attention if you experience severe side effects such as seizures, hallucinations, or severe abdominal pain.

Quick Tips for OFLOTAS IV INJECTION 100 ML

**Use as Directed:** Always administer OFLOTAS IV INJECTION 100 ML exactly as prescribed by your doctor. Adhering to the prescribed dosage and duration is crucial for optimal effectiveness and to minimize the risk of side effects. Never self-adjust the dose or discontinue treatment without consulting your healthcare provider.
**Administered by Healthcare Professionals:** OFLOTAS IV INJECTION 100 ML should only be administered by trained healthcare professionals in a clinical setting. This ensures proper administration, monitoring for potential adverse reactions, and immediate access to medical support if needed. Do not attempt to self-administer this medication.
**Hydration is Key:** Maintain adequate hydration while receiving OFLOTAS IV INJECTION 100 ML. Drinking plenty of fluids helps to support kidney function and can reduce the risk of certain side effects. Consult your doctor about the appropriate amount of fluid intake for you during treatment.
**Inform Your Doctor About Existing Conditions and Medications:** Before starting OFLOTAS IV INJECTION 100 ML, inform your doctor about all your existing medical conditions, especially any kidney or liver problems, heart conditions, or neurological disorders. Also, provide a comprehensive list of all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This information helps your doctor to assess potential drug interactions and ensure safe and effective treatment.
**Be Aware of Potential Side Effects:** Like all medications, OFLOTAS IV INJECTION 100 ML can cause side effects. Common side effects may include nausea, vomiting, diarrhea, and injection site reactions. More serious side effects are rare but can include allergic reactions, seizures, and tendon problems. If you experience any unusual or concerning symptoms, seek immediate medical attention. Report any side effects to your doctor promptly.

Food Interactions with OFLOTAS IV INJECTION 100 ML

OFLOTAS IV INJECTION 100 ML is generally administered by a healthcare professional and is unlikely to be affected by food. However, it is best to follow your doctor's instructions regarding diet while on medication.

FAQs

What is OFLOTAS IV INJECTION 100 ML used for?

OFLOTAS IV INJECTION 100 ML is used to treat various bacterial infections, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and bone and joint infections.

How is OFLOTAS IV INJECTION 100 ML administered?

OFLOTAS IV INJECTION 100 ML is administered intravenously (IV) by a healthcare professional. It is usually given as an intravenous infusion.

What are the common side effects of OFLOTAS IV INJECTION 100 ML?

Common side effects of OFLOTAS IV INJECTION 100 ML may include nausea, vomiting, diarrhea, headache, and injection site reactions.

How should OFLOTAS IV INJECTION 100 ML be stored?

OFLOTAS IV INJECTION 100 ML should be stored at room temperature, away from direct sunlight and heat.

Is OFLOTAS IV INJECTION 100 ML safe during pregnancy?

The safety of OFLOTAS IV INJECTION 100 ML during pregnancy has not been established. It should only be used if clearly needed and prescribed by a doctor.

Is OFLOTAS IV INJECTION 100 ML safe during breastfeeding?

OFLOTAS IV INJECTION 100 ML may be excreted in breast milk. It is important to consult a doctor before using it while breastfeeding.

Can OFLOTAS IV INJECTION 100 ML interact with other medications?

OFLOTAS IV INJECTION 100 ML can interact with certain medications, such as anticoagulants and theophylline. Inform your doctor about all the medications you are taking.

What are the symptoms of an overdose of OFLOTAS IV INJECTION 100 ML?

Symptoms of an overdose of OFLOTAS IV INJECTION 100 ML may include nausea, vomiting, dizziness, confusion, and seizures.

What should I do if I miss a dose of OFLOTAS IV INJECTION 100 ML?

If you miss a dose of OFLOTAS IV INJECTION 100 ML, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

What is the duration of treatment with OFLOTAS IV INJECTION 100 ML?

The duration of treatment with OFLOTAS IV INJECTION 100 ML depends on the type and severity of the infection. Your doctor will determine the duration of treatment.

Is it safe to drink alcohol while taking OFLOTAS IV INJECTION 100 ML?

It is not recommended to drink alcohol while taking OFLOTAS IV INJECTION 100 ML, as it can increase the risk of side effects.

Is OFLOTAS IV INJECTION 100 ML safe for children?

OFLOTAS IV INJECTION 100 ML should be used with caution in children and only under the advice of a doctor.

What are the serious side effects of OFLOTAS IV INJECTION 100 ML?

Serious side effects of OFLOTAS IV INJECTION 100 ML may include allergic reactions, tendinitis, and nerve damage. Seek immediate medical attention if you experience any of these side effects.

What precautions should I take while taking OFLOTAS IV INJECTION 100 ML?

While taking OFLOTAS IV INJECTION 100 ML, inform your doctor about all your medical conditions and allergies. Avoid prolonged exposure to sunlight and drink plenty of fluids.

What is the mechanism of action of OFLOTAS IV INJECTION 100 ML?

OFLOTAS IV INJECTION 100 ML works by inhibiting the DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication, transcription, and repair.

References

Ofloxacin in 5% Dextrose Injection - FDA Package Insert. This FDA document provides detailed information about Ofloxacin intravenous injection, including its composition, clinical pharmacology, indications, dosage, and safety information. While not specific to 'OFLOTAS IV', it covers the general drug.

DrugBank entry for Ofloxacin. DrugBank provides detailed chemical and pharmaceutical information about Ofloxacin, including its structure, properties, uses, and interactions.

PubMed Central. A free archive of biomedical and life sciences literature. Searching for 'Ofloxacin intravenous' or 'Ofloxacin pharmacokinetics' will yield research articles on the drug's properties and uses.

European Medicines Agency. The EMA website contains scientific guidelines and information on authorized medicines in the European Union. Searching for Ofloxacin will provide regulatory information.

Micromedex. A comprehensive drug information database that contains information about Ofloxacin, including its uses, dosages, side effects, and interactions. (Subscription required)

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INTAS PHARMACEUTICALS LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

OFLOTAS IV INJECTION 100 ML

OFLOTAS IV INJECTION 100 ML

Product Details

About OFLOTAS IV INJECTION 100 ML

Uses of OFLOTAS IV INJECTION 100 ML

How OFLOTAS IV INJECTION 100 ML Works

Side Effects of OFLOTAS IV INJECTION 100 ML

Safety Advice for OFLOTAS IV INJECTION 100 ML

Dosage of OFLOTAS IV INJECTION 100 ML

What if I miss my dose of OFLOTAS IV INJECTION 100 ML?

How to store OFLOTAS IV INJECTION 100 ML?

Benefits of OFLOTAS IV INJECTION 100 ML

How to use OFLOTAS IV INJECTION 100 ML

Quick Tips for OFLOTAS IV INJECTION 100 ML

Food Interactions with OFLOTAS IV INJECTION 100 ML

FAQs

What is OFLOTAS IV INJECTION 100 ML used for?

How is OFLOTAS IV INJECTION 100 ML administered?

What are the common side effects of OFLOTAS IV INJECTION 100 ML?

How should OFLOTAS IV INJECTION 100 ML be stored?

Is OFLOTAS IV INJECTION 100 ML safe during pregnancy?

Is OFLOTAS IV INJECTION 100 ML safe during breastfeeding?

Can OFLOTAS IV INJECTION 100 ML interact with other medications?

What are the symptoms of an overdose of OFLOTAS IV INJECTION 100 ML?

What should I do if I miss a dose of OFLOTAS IV INJECTION 100 ML?

What is the duration of treatment with OFLOTAS IV INJECTION 100 ML?

Is it safe to drink alcohol while taking OFLOTAS IV INJECTION 100 ML?

Is OFLOTAS IV INJECTION 100 ML safe for children?

What are the serious side effects of OFLOTAS IV INJECTION 100 ML?

What precautions should I take while taking OFLOTAS IV INJECTION 100 ML?

What is the mechanism of action of OFLOTAS IV INJECTION 100 ML?

References

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