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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

General Safety and Chronic Use
Requires close monitoringLong-term or repeated courses of Omnacortil 10 increase the risk of systemic side effects including osteoporosis, muscle weakness, Cushingoid features, cataracts, glaucoma, and increased susceptibility to infections.
OMNACORTIL 10MG TABLET 10'S belongs to the class of corticosteroids which has anti-inflammatory properties. It works by suppressing the inflammation associated with many diseases, for example, arthritis. Therefore, OMNACORTIL 10MG TABLET 10'S is used for the treatment of a number of inflammatory and auto-immune conditions.
It is advisable to take OMNACORTIL 10MG TABLET 10'S for the duration prescribed by your doctor. Do not stop the treatment suddenly or take for a longer period than recommended by your doctor.
No, OMNACORTIL 10MG TABLET 10'S does not contain penicillin. OMNACORTIL 10MG TABLET 10'S belongs to a group of medicines called steroids.
Yes, OMNACORTIL 10MG TABLET 10'S does expire. All the medicines come with an expiry date mentioned on the pack. You must check the expiry date before using any medicine.
No, OMNACORTIL 10MG TABLET 10'S is not a painkiller. OMNACORTIL 10MG TABLET 10'S belongs to a group of medicines called steroids which are anti-inflammatory in nature. The medicine can help in pain relief which is caused due to inflammation.
OMNACORTIL 10MG TABLET 10'S is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
OMNACORTIL 10MG TABLET 10'S has immunosuppressant properties which means it suppresses the body’s immune system. Hence, OMNACORTIL 10MG TABLET 10'S is used for the treatment of a number of inflammatory and auto-immune conditions.
Yes, OMNACORTIL 10MG TABLET 10'S is a glucocorticoid. It belongs to a group of medicines called steroids (corticosteroids).
Certain antibiotics may increase the metabolism of OMNACORTIL 10MG TABLET 10'S and hence decrease its effects. So, if you are already taking antibiotics then it may be necessary to adjust the dose of OMNACORTIL 10MG TABLET 10'S accordingly. Hence, consult your doctor before taking OMNACORTIL 10MG TABLET 10'S with antibiotics.
Yes, OMNACORTIL 10MG TABLET 10'S can be taken with paracetamol. No drug-drug interactions have been reported when used together. However, in some cases interactions may occur. Please consult your doctor before taking the two medicines together.
Omnacortil 10 is a prescription medicine that contains prednisolone, a synthetic corticosteroid (glucocorticoid). Prednisolone reduces inflammation and suppresses the immune response. It is used in a variety of conditions such as allergic disorders, asthma exacerbations, certain skin diseases, autoimmune conditions, and some kidney and blood disorders. The exact strength and formulation should be confirmed on the pack and with your pharmacist or doctor.
Omnacortil 10 may be prescribed for acute and chronic inflammatory or allergic conditions. These include asthma and chronic obstructive airway disease exacerbations, severe allergic reactions, urticaria and other allergic skin diseases, eczema and dermatitis, rheumatoid arthritis and other autoimmune joint diseases, inflammatory bowel disease, nephrotic syndrome, certain blood disorders such as immune thrombocytopenia, and some autoimmune or connective tissue diseases. It may also be used in specific cancer or transplant protocols under specialist supervision.
Take Omnacortil 10 exactly as prescribed by your doctor. It is usually taken by mouth with water, preferably with or after food to reduce stomach irritation. Many clinicians advise taking the full daily dose in the morning to align with the body’s natural cortisol rhythm and to reduce sleep disturbance, but follow the schedule given by your prescriber. Do not change the dose, frequency, or duration on your own, and do not stop the medicine suddenly if you have been taking it for more than a short course unless your doctor instructs you to taper it.
You should not stop Omnacortil 10 abruptly if you have been taking it for more than a short period, as sudden discontinuation can lead to adrenal insufficiency. This occurs because long-term corticosteroid use suppresses the body’s own cortisol production. Stopping suddenly may cause fatigue, weakness, low blood pressure, nausea, and in severe cases, a medical emergency. Your doctor will usually reduce the dose gradually (tapering) to allow your adrenal glands to recover. Always follow the tapering schedule provided by your healthcare professional.
Common side effects of Omnacortil 10 (prednisolone) include increased appetite, weight gain, fluid retention and swelling, mood changes such as irritability or euphoria, difficulty sleeping, indigestion or stomach discomfort, and increased blood pressure or blood sugar in susceptible individuals. With longer-term use, there is a risk of Cushingoid appearance (round face, central weight gain), thinning of the skin, easy bruising, acne, muscle weakness, osteoporosis, cataracts or glaucoma, and increased susceptibility to infections. Not everyone experiences these effects, but you should report any troublesome or unexpected symptoms to your doctor.
Yes. Prednisolone can increase blood sugar levels and may worsen existing diabetes or unmask a tendency to diabetes. It can also cause fluid retention and may raise blood pressure, particularly in people with pre-existing hypertension or cardiovascular disease. If you have diabetes or high blood pressure, your doctor may need to adjust your other medications and monitor your readings more closely while you are taking Omnacortil 10. Inform your healthcare provider promptly if you notice increased thirst, frequent urination, headaches, or swelling of the ankles or feet.
Alcohol intake should be limited while taking Omnacortil 10. Both alcohol and prednisolone can irritate the stomach lining and increase the risk of gastritis or peptic ulcer disease, especially at higher doses or with prolonged use. Excessive alcohol consumption may therefore increase the risk of gastrointestinal bleeding. Occasional small amounts of alcohol may be permissible for some patients, but this should be discussed with your doctor, particularly if you have a history of stomach ulcers, liver disease, or heavy alcohol use.
Systemic corticosteroids like prednisolone are used during pregnancy only when clearly needed and when the expected benefit to the mother outweighs potential risks to the fetus. Prednisolone crosses the placenta, and long-term or high-dose use in pregnancy has been associated with potential risks such as reduced fetal growth and, rarely, effects on the baby’s adrenal function. However, uncontrolled maternal disease can also harm the pregnancy. If you are pregnant or planning to become pregnant, do not start or stop Omnacortil 10 without consulting your obstetrician or treating specialist. The dose and duration should be kept as low and as short as possible consistent with disease control.
Prednisolone passes into breast milk in small amounts. At low to moderate doses, many guidelines consider it compatible with breastfeeding, especially if doses are taken immediately after a feed and there is a gap before the next feeding. However, higher or prolonged doses may pose a risk of adrenal suppression or growth effects in the infant, although this is uncommon. Decisions should be individualized. Discuss your specific dose and treatment duration with your doctor and your child’s pediatrician to determine whether breastfeeding can continue and whether any monitoring of the infant is needed.
Yes. Omnacortil 10 can interact with several medicines. Drugs that affect liver enzymes, such as certain anticonvulsants (for example, phenytoin, carbamazepine), rifampicin, and some antifungals or HIV medicines, can alter prednisolone levels. Nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of stomach ulcers when combined with corticosteroids. Prednisolone may also affect the action of blood thinners such as warfarin and some antidiabetic medicines. Live vaccines (for example, some forms of measles, mumps, rubella, varicella, and certain oral vaccines) are generally avoided during treatment with immunosuppressive doses of corticosteroids. Always inform your doctor and pharmacist about all medicines, supplements, and vaccines you are taking or planning to receive.
Prednisolone suppresses the immune system and can increase your susceptibility to infections or worsen existing infections. You should avoid close contact with people who have contagious illnesses such as chickenpox, measles, or influenza, especially if you have not had these infections or been vaccinated. Inform your doctor immediately if you develop fever, sore throat, persistent cough, painful urination, or any signs of infection. If you have a history of tuberculosis, hepatitis, or other chronic infections, your doctor may screen and monitor you more closely. Do not receive live vaccines without explicit approval from your treating physician while on immunosuppressive doses.
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