ONIVYDE 43MG/10ML INJECTION
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ONIVYDE 43MG/10ML INJECTION
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ONIVYDE 43MG/10ML INJECTION

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ONIVYDE 43MG/10ML INJECTION

By SERVIER INDIA PRIVATE LIMITED

MRP

₹

99000

₹89100

10 % OFF

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Product DetailsArrow

About ONIVYDE 43MG/10ML INJECTION

  • ONIVYDE 43MG/10ML INJECTION is an anti-cancer medicine, also known as a cytostatic. It contains Irinotecan hydrochloride trihydrate. This medicine is used to treat advanced colon and rectal cancer in adults. It might be used by itself or together with other cancer treatments. Colon and rectal cancer commonly affects people over 50 and can be influenced by genetics and lifestyle factors.
  • The most common side effects of ONIVYDE 43MG/10ML INJECTION are low blood cell counts (affecting red blood cells, white blood cells, and platelets – this is called myelosuppression or bone marrow suppression) and diarrhea, which can sometimes be severe. Other common side effects include feeling sick (nausea), vomiting, stomach pain, constipation, feeling tired (fatigue), fever, infections (including serious ones like sepsis), changes in liver tests (abnormal bilirubin), hair loss, and weight loss. It's important to tell your doctor if these side effects are severe, bothersome, or don't go away. Also, inform your doctor if you have ongoing issues with your gut, like chronic inflammatory bowel disease or a blocked intestine, or if you have recently received any 'live' vaccines.
  • Before starting treatment with ONIVYDE 43MG/10ML INJECTION, tell your doctor about *all* your medical conditions. This includes if you are allergic to this medicine or any of its ingredients. It's very important to mention if you have or have ever had liver problems (including jaundice), kidney issues, heart problems, asthma, high blood pressure, high cholesterol, or severe diarrhea. Your doctor also needs to know if you smoke or have received radiation therapy in the past. Be sure to tell your doctor about *all* medicines you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements, as they could interact with ONIVYDE. To prevent pregnancy during and for a period after treatment, both men and women receiving this injection must use effective birth control. Your doctor will arrange for regular blood tests before and during your treatment. These tests are crucial to monitor your blood cell counts, liver function, and overall health, helping the doctor adjust your treatment plan and manage potential side effects safely. Maintaining good hydration and nutrition during treatment is also often recommended; discuss this with your healthcare team. Always follow your doctor's instructions carefully regarding dosage and appointments.

Uses of ONIVYDE 43MG/10ML INJECTION

  • Treats colon and rectum (large intestine) cancer that has spread.

Side Effects of ONIVYDE 43MG/10ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. This safety advice description is specific to ONIVYDE 43MG/10ML INJECTION.

Safety Advice for ONIVYDE 43MG/10ML INJECTIONArrow

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Pregnancy

UNSAFE

ONIVYDE 43MG/10ML INJECTION is unsafe during pregnancy as it may harm the developing baby. Women with potential childbearing use effective contraceptives during and after six months after treatment.

Dosage of ONIVYDE 43MG/10ML INJECTIONArrow

  • Your treatment with ONIVYDE 43MG/10ML INJECTION requires careful administration exactly as directed by your doctor. This medication is given directly into your vein by a trained healthcare professional in a hospital or clinic setting. It is crucial that you do not attempt to self-administer ONIVYDE 43MG/10ML INJECTION at home.
  • Before you begin treatment with this medicine, your physician will likely recommend a specific genetic test, often called a DNA test. This test helps understand how your body processes certain medications, which can influence how effective ONIVYDE 43MG/10ML INJECTION might be for you and help identify potential risks. Your doctor will determine the precise dose of ONIVYDE 43MG/10ML INJECTION and the length of your treatment course. This decision is highly personalized and depends on several factors, including your age, body weight, the specific disease being treated, your general health, and how your body responds to the medication. The dosage schedule is carefully planned to optimize the treatment effect while managing potential side effects. Regular follow-up appointments will be scheduled to monitor your progress and adjust the dose or duration if necessary.

How to store ONIVYDE 43MG/10ML INJECTION?Arrow

  • Keep ONIVYDE 43MG INJ 10ML away from the reach of children and pets.
  • Store ONIVYDE 43MG INJ 10ML at room temperature.

Benefits of ONIVYDE 43MG/10ML INJECTIONArrow

  • Irinotecan is a chemotherapy medication used to treat certain types of cancer. It's administered in an inactive form called a prodrug. Once inside the body, particularly in the liver, special enzymes transform Irinotecan into its highly active substance known as SN-38. This active form, SN-38, works by targeting and inhibiting a key enzyme inside cells called Topoisomerase I. Topoisomerase I plays a crucial role in managing DNA; it helps untangle the DNA strands during important processes like cell division, allowing the genetic information to be accessed and copied. By blocking Topoisomerase I, SN-38 prevents the DNA from relaxing and unwinding properly. This interference leads to breaks and severe damage in the cancer cell's DNA. With damaged DNA that cannot be repaired or replicated, the cancer cells are unable to divide, grow, or spread effectively. This mechanism ultimately prevents the uncontrolled multiplication of cancer cells, helping to slow down tumor growth and manage the disease.

How to use ONIVYDE 43MG/10ML INJECTIONArrow

  • ONIVYDE 43MG/10ML INJECTION is administered strictly according to the instructions provided by your healthcare professional. This medicine is specifically designed to be given directly into your vein (intravenously) and is not suitable for self-administration. A trained healthcare provider in a hospital or clinic setting will perform the administration, ensuring the medicine is delivered correctly and safely into your bloodstream. It is crucial that you do not attempt to inject this medicine yourself.
  • Before you begin treatment with ONIVYDE 43MG/10ML INJECTION, your physician will likely recommend certain tests, including a specific DNA test. This test, often looking at the UGT1A1 gene, helps your doctor understand how your body might process the medicine and predict potential side effects. Your physician will use the results of these tests, along with factors such as your age, body weight, overall health condition, and the specific characteristics of your disease, to determine the precise dosage and the duration of your treatment plan.
  • Adhering exactly to the dosage, schedule, and duration prescribed by your physician is vital for the effectiveness and safety of your treatment. Do not miss any scheduled appointments for receiving ONIVYDE 43MG/10ML INJECTION. It is important to communicate immediately with your healthcare team about any side effects, concerns, or changes in your health status during the course of treatment. This ongoing communication helps ensure that your therapy remains as safe and effective as possible.

FAQs

Do you lose your hair with ONIVYDE 43MG/10ML INJECTION?Arrow

Hair loss can be a possible side effect of using ONIVYDE 43MG/10ML INJECTION. It is recommended to discuss this potential side effect with your doctor for further information and guidance.

Does ONIVYDE 43MG/10ML INJECTION cause liver damage?Arrow

ONIVYDE 43MG/10ML INJECTION may cause liver impairment or damage. Inform your physician before starting treatment if you have liver disease or jaundice. Your doctor may adjust the dose based on your medical condition.

What are the serious side effects of ONIVYDE 43MG/10ML INJECTION?Arrow

Some serious side effects of ONIVYDE 43MG/10ML INJECTION are early and late, diarrhea, allergic reactions, kidney impairment, lung problems, and low levels of RBC, WBC, and platelets in the blood.

How to prevent diarrhea while taking ONIVYDE 43MG/10ML INJECTION?Arrow

Drink large amounts of water and rehydration fluids to prevent diarrhea. It is advised to take antidiarrheal medicines, including loperamide.

What should I do if I miss a dose of ONIVYDE 43MG/10ML INJECTION?Arrow

If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose of ONIVYDE 43MG/10ML INJECTION.

What are the potential interactions of ONIVYDE 43MG/10ML INJECTION with other drugs?Arrow

It is important to inform your doctor about all medications, supplements, and herbal products you are currently taking before starting treatment with ONIVYDE 43MG/10ML INJECTION. This is because it may interact with certain substances, potentially affecting its effectiveness or increasing the risk of side effects. Your doctor can assess potential interactions and adjust your treatment plan if necessary.

What special precautions should I take regarding kidney issues and diarrhea while using ONIVYDE 43MG/10ML INJECTION?Arrow

ONIVYDE 43MG/10ML INJECTION should be used cautiously in patients with kidney disease or those on dialysis. Diarrhea is a common side effect and can be serious, especially if it starts more than 24 hours after administration. It requires immediate treatment and close monitoring to prevent dehydration and life-threatening imbalances.

How should I manage diarrhea and other side effects while taking ONIVYDE 43MG/10ML INJECTION?Arrow

If you experience diarrhea, drink plenty of water and rehydration fluids immediately. Avoid laxatives and stool softeners unless advised by your doctor. Take antidiarrheal medicines like loperamide as recommended. Notify your doctor about any serious side effects. Do not stop the medicine or double the dose without consulting your doctor.

What is the main component of ONIVYDE 43MG/10ML INJECTION?Arrow

ONIVYDE 43MG/10ML INJECTION contains IRINOTECAN as its main molecule or active component.

What is ONIVYDE 43MG/10ML INJECTION used for?Arrow

ONIVYDE 43MG/10ML INJECTION is an anti-cancer medication used in the treatment of specific types of cancers. It works by targeting and killing cancer cells.

References

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Accord Healthcare Limited, Electronic Medicines Compendium (EMC)

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Pharmacia & Upjohn Co, US Food & Drug Administration

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Ratings & Review

Awesome experience every time i get medicine on time and they have delivery on time also staff are very cooperative and knowledgeable

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Reviewed on 22-06-2023

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Excellent service

Ali Akhtar

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Reviewed on 26-07-2023

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(5/5)

Nice service All required drugs are available 😊

Meet Dobariya

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Reviewed on 13-01-2024

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(5/5)

Geniune medicines available at good discounts

Vaishali Parikh

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Reviewed on 05-12-2022

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(5/5)

Good

tarif Malek

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Reviewed on 15-01-2024

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(5/5)

Marketer / Manufacturer Details

SERVIER INDIA PRIVATE LIMITED

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ONIVYDE 43MG/10ML INJECTION

ONIVYDE 43MG/10ML INJECTION

MRP

₹

99000

₹89100

10 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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