PALBINAS 100 CAPSULE 21'S
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PALBINAS 100 CAPSULE 21'S
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PALBINAS 100 CAPSULE 21'S

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PALBINAS 100 CAPSULE 21'S

By GLENMARK PHARMACEUTICALS LIMITED

MRP

6400

₹5120

20 % OFF

₹243.81 Only /

CAPSULE

10

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Product DetailsArrow

About PALBINAS 100 CAPSULE 21'S

  • PALBINAS 100 CAPSULE 21'S contains palbociclib, a targeted therapy that belongs to the class of anticancer drugs known as cyclin-dependent kinase (CDK) inhibitors. It is specifically designed to treat hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced or metastatic breast cancer, where the cancer has spread to other parts of the body. Cancer occurs when cells divide uncontrollably and abnormally. This medication is administered in conjunction with other anticancer drugs to enhance its effectiveness. PALBINAS 100 CAPSULE 21'S works by blocking specific proteins (CDKs) that promote cancer cell growth, thereby slowing down or stopping the spread of cancer.
  • Common side effects associated with PALBINAS 100 CAPSULE 21'S include nausea, vomiting, diarrhea, fatigue, hair loss, dry skin, rash, infections, nosebleeds, decreased appetite, low blood cell counts, swelling of the lips and mouth, changes in taste, dry eyes, blurred vision, and increased tearing. It's important to inform your doctor if any of these side effects become bothersome or persist. Managing these side effects proactively can improve your overall comfort during treatment.
  • Before starting PALBINAS 100 CAPSULE 21'S, inform your healthcare provider if you have any allergies to palbociclib or any of the other ingredients in the capsule. It's crucial to disclose any existing medical conditions, such as infections (e.g., fever, chills, sore throat), liver disorders, kidney disorders, or intolerance to certain sugars. Contact your doctor immediately if you experience symptoms like dry cough, chest pain, or difficulty breathing, as these could indicate lung inflammation. Also, inform your doctor about all medications, supplements, and herbal remedies you are currently taking. Women of childbearing age should use effective birth control during treatment and for at least three weeks after the last dose. PALBINAS 100 CAPSULE 21'S is generally not recommended for adolescents and children under 18 years of age. Regular monitoring and open communication with your healthcare team are essential for safe and effective treatment.

Uses of PALBINAS 100 CAPSULE 21'S

  • Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

Side Effects of PALBINAS 100 CAPSULE 21'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects include blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) and lung inflammation (chest pain, dry cough, or difficulty breathing).

  • Tiredness
  • Hair loss
  • Dry skin, rash
  • Infections
  • Low blood cell counts
  • Decreased of appetite
  • Nausea, vomiting
  • Diarrhea
  • Swelling of lips and mouth
  • Changes in taste
  • Nose bleed
  • Dry eye, blurred vision, increased tearing

Safety Advice for PALBINAS 100 CAPSULE 21'SArrow

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Pregnancy

UNSAFE

It is not recommended to take PALBINAS 100 CAPSULE 21'S during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Dosage of PALBINAS 100 CAPSULE 21'SArrow

  • Take PALBINAS 100 CAPSULE 21'S precisely as instructed by your healthcare provider. This medication is typically prescribed to be taken once daily, and it's crucial to adhere to a consistent schedule by taking it at the same time each day. For optimal absorption and to minimize potential stomach upset, it is recommended to take PALBINAS 100 CAPSULE 21'S with food. Ensure you swallow the capsule whole with a full glass of water. Avoid any alteration to the capsule's form, such as crushing, breaking, or chewing, as this could affect the way the medication is released and absorbed in your body. If you have any difficulties swallowing capsules, discuss this with your doctor or pharmacist, as they may be able to offer alternative formulations or helpful strategies. Always follow your doctor's specific directions regarding dosage and administration.

How to store PALBINAS 100 CAPSULE 21'S?Arrow

  • Keep PALBINAS 100MG CAP 1X21 away from the reach of children and pets.
  • Store PALBINAS 100MG CAP 1X21 at room temperature.

Benefits of PALBINAS 100 CAPSULE 21'SArrow

  • PALBINAS 100 CAPSULE 21'S is a targeted therapy that specifically inhibits the activity of cyclin-dependent kinases 4 and 6 (CDK4/6). These enzymes play a crucial role in cell division and proliferation. By selectively blocking CDK4/6, PALBINAS 100 CAPSULE 21'S disrupts the cell cycle progression, particularly the transition from the G1 to S phase. This disruption effectively halts the uncontrolled growth of cancer cells.
  • The primary mechanism of PALBINAS 100 CAPSULE 21'S involves preventing the phosphorylation of retinoblastoma protein (Rb), a tumor suppressor protein. When CDK4/6 are active, they phosphorylate Rb, which inactivates it and allows cells to progress through the cell cycle. By inhibiting CDK4/6, PALBINAS 100 CAPSULE 21'S keeps Rb in its active, unphosphorylated state. This prevents the cell from entering the S phase, where DNA replication occurs, and thereby suppresses cell division.
  • Through this targeted action, PALBINAS 100 CAPSULE 21'S effectively slows down the growth of cancer cells and prevents them from spreading to other parts of the body. This makes it a valuable treatment option for certain types of cancer, particularly hormone receptor-positive, HER2-negative breast cancer. The medication is often used in combination with other therapies, such as hormone therapy, to achieve optimal results in managing the disease. Its precision targeting helps minimize damage to healthy cells, reducing the severity of side effects often associated with traditional chemotherapy.

How to use PALBINAS 100 CAPSULE 21'SArrow

  • Always adhere to your doctor's instructions when taking PALBINAS 100 CAPSULE 21'S. This medication is intended for once-daily use, and it's crucial to take it at the same time each day to maintain a consistent level in your system. For optimal absorption and to minimize potential stomach upset, take the capsule with food. Swallow the capsule whole with a full glass of water; avoid crushing, breaking, or chewing it, as this could affect how the medication is released and absorbed by your body.
  • Consistency is key when it comes to medication like PALBINAS 100 CAPSULE 21'S. Setting a daily reminder can help you remember to take your dose at the same time each day. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's also important to inform your doctor about any other medications, supplements, or herbal remedies you are currently taking, as they could interact with PALBINAS 100 CAPSULE 21'S. If you experience any unusual side effects while taking this medication, contact your doctor immediately. Remember that this medication is prescribed for your specific condition, and it should not be shared with others, even if they have similar symptoms.
  • Store PALBINAS 100 CAPSULE 21'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. If you have any questions or concerns about how to take this medication properly, don't hesitate to ask your doctor or pharmacist for clarification.

FAQs

Is PALBINAS 100 CAPSULE 21'S a targeted therapy?Arrow

Yes, PALBINAS 100 CAPSULE 21'S is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.

Do you lose hair on PALBINAS 100 CAPSULE 21'S?Arrow

Yes, Taking PALBINAS 100 CAPSULE 21'S can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.

Can children use PALBINAS 100 CAPSULE 21'S?Arrow

No, PALBINAS 100 CAPSULE 21'S is not recommended for adolescents and children under 18.

Does PALBINAS 100 CAPSULE 21'S affect fertility?Arrow

Yes, PALBINAS 100 CAPSULE 21'S may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.

Does PALBINAS 100 CAPSULE 21'S affect blood cell count?Arrow

PALBINAS 100 CAPSULE 21'S might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking PALBINAS 100 CAPSULE 21'S are advised.

Is there any interaction of PALBINAS 100 CAPSULE 21'S with other drugs?Arrow

NULL interaction of PALBINAS 100 CAPSULE 21'S with other drungs

What advice should be followed during PALBINAS 100 CAPSULE 21'S treatment?Arrow

During PALBINAS 100 CAPSULE 21'S treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether PALBINAS 100 CAPSULE 21'S affects your blood cells.

What molecule is used for making PALBINAS 100 CAPSULE 21'S?Arrow

PALBOCICLIB is molecule/combination used for making PALBINAS 100 CAPSULE 21'S.

For which ailments/diseases/conditions is PALBINAS 100 CAPSULE 21'S prescribed?Arrow

PALBINAS 100 CAPSULE 21'S is prescribed for {Oncology} ailments/diseases/conditions.

References

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Pfizer Limited, Electronic medicines compendium (emc)

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Pfizer Labs, US Food and Drug Administration

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Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy

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Palbace; Pfizer

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Ratings & Review

Often get medicines at a cheaper rate. Almost 50% cheaper

vivaan shah

Reviewed on 10-06-2023

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(5/5)

Great experience wonderful experience nice palce for low cost medicine

vast chance

Reviewed on 10-06-2023

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(5/5)

Good service and discount. Help me to get a good discount on some of my daily meds

Yogesh Chawla

Reviewed on 05-08-2023

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(5/5)

Same day dilevery available, Urgent response, Free home delivery above 500

Vikas Yadav

Reviewed on 09-07-2023

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(5/5)

I find medcart really a good farmacy and their service is the most efficient. Highly recommended for reasonably priced medicines

Medha Joshi

Reviewed on 07-03-2024

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(5/5)


Marketer / Manufacturer Details

GLENMARK PHARMACEUTICALS LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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